Jung-Ying Tzeng

Visiting Professor

  • 3889 Citations
  • 19 h-Index
19982019
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Research Output 1998 2019

  • 3889 Citations
  • 19 h-Index
  • 53 Article
  • 2 Comment/debate
  • 2 Letter
  • 2 Review article
2019

Efficient Signal Inclusion With Genomic Applications

Jeng, X. J., Zhang, T. & Tzeng, J. Y., 2019 Oct 2, In : Journal of the American Statistical Association. 114, 528, p. 1787-1799 13 p.

Research output: Contribution to journalArticle

Genomics
Proportion
Single nucleotide Polymorphism
Inclusion
Adaptive Procedure

Genetic loci determining total immunoglobulin E levels from birth through adulthood

Yao, T. C., Chung, R. H., Lin, C. Y., Tsai, P. C., Chang, W. C., Yeh, K. W., Tsai, M. H., Liao, S. L., Hua, M. C., Lai, S. H., Chen, L. C., Chang, S. W., Yu, Y. W., Hsu, J. Y., Chang, S. C., Cheng, W. C., Hu, D., Hong, X., Burchard, E. G., Wang, X. & 3 others, Tzeng, J-Y., Tsai, H. J. & Huang, J. L., 2019 Mar 1, In : Allergy: European Journal of Allergy and Clinical Immunology. 74, 3, p. 621-625 5 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Identifying individual risk rare variants using protein structure guided local tests (POINT)

West, R. M., Lu, W., Rotroff, D. M., Kuenemann, M. A., Chang, S. M., Wu, M. C., Wagner, M. J., Buse, J. B., Motsinger-Reif, A. A., Fourches, D. & Tzeng, J. Y., 2019 Feb 1, In : PLoS Computational Biology. 15, 2, e1006722.

Research output: Contribution to journalArticle

Open Access
Protein Structure
protein structure
Aggregation
Agglomeration
Kernel Machines

Reference equations for spirometry in healthy Asian children aged 5 to 18 years in Taiwan

Chang, S. M., Tsai, H. J., Tzeng, J. Y., Yeh, K. W., Chen, L. C., Lai, S. H., Liao, S. L., Hua, M. C., Tsai, M. H., Huang, J. L. & Yao, T. C., 2019 Nov, In : World Allergy Organization Journal. 12, 11, 100074.

Research output: Contribution to journalArticle

Open Access
Spirometry
Taiwan
Lung
Linear Models
Reference Values
2018

A Powerful Test for SNP Effects on Multivariate Binary Outcomes Using Kernel Machine Regression

Davenport, C. A., Maity, A., Sullivan, P. F. & Tzeng, J-Y., 2018 Apr 1, In : Statistics in Biosciences. 10, 1, p. 117-138 22 p.

Research output: Contribution to journalArticle

Kernel Machines
Binary Outcomes
Single Nucleotide Polymorphism
Regression
Polymorphism
5 Citations (Scopus)

Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study

Green, A. J., Hoyo, C., Mattingly, C. J., Luo, Y., Tzeng, J. Y., Murphy, S. K., Buchwalter, D. B. & Planchart, A., 2018 Jul 1, In : International Journal of Obesity. 42, 7, p. 1285-1295 11 p.

Research output: Contribution to journalArticle

Zebrafish
Cadmium
Obesity
Heavy Metals
Epigenomics

Inference on phenotype-specific effects of genes using multivariate kernel machine regression

Maity, A., Zhao, J., Sullivan, P. F. & Tzeng, J-Y., 2018 Feb 1, In : Genetic Epidemiology. 42, 1, p. 64-79 16 p.

Research output: Contribution to journalArticle

Phenotype
Genes
Genetic Markers
Antipsychotic Agents
Clinical Trials
1 Citation (Scopus)

On the substructure controls in rare variant analysis: Principal components or variance components?

Luo, Y., Maity, A., Wu, M. C., Smith, C., Duan, Q., Li, Y. & Tzeng, J-Y., 2018 Apr 1, In : Genetic Epidemiology. 42, 3, p. 276-287 12 p.

Research output: Contribution to journalArticle

Principal Component Analysis
Population
Analysis of Variance

Reexamining dis/similarity-based tests for rare-variant association with case-control samples

Wang, C., Tzeng, J-Y., Wu, P. Z., Preisig, M. & Hsiao, C. K., 2018 May 1, In : Genetics. 209, 1, p. 105-113 9 p.

Research output: Contribution to journalArticle

Open Access
Phenotype
Individuality
Sample Size
Single Nucleotide Polymorphism
Power (Psychology)

Rejoinder to “A note on testing and estimation in marker-set association study using semiparametric quantile regression kernel machine”

Kong, D., Maity, A., Hsu, F. C. & Tzeng, J-Y., 2018 Jun 1, In : Biometrics. 74, 2, p. 767-768 2 p.

Research output: Contribution to journalArticle

2017
Binary Response
Small Sample Size
Screening
Regression
Posterior Mean
19 Citations (Scopus)

Maternal blood cadmium, lead and arsenic levels, nutrient combinations, and offspring birthweight

Luo, Y., McCullough, L. E., Tzeng, J. Y., Darrah, T., Vengosh, A., Maguire, R. L., Maity, A., Samuel-Hodge, C., Murphy, S. K., Mendez, M. A. & Hoyo, C., 2017 Apr 24, In : BMC Public Health. 17, 1, 354.

Research output: Contribution to journalArticle

Open Access
Arsenic
Cadmium
Metals
Mothers
Poisons
2016
2 Citations (Scopus)

Across-Platform Imputation of DNA Methylation Levels Incorporating Nonlocal Information Using Penalized Functional Regression

Zhang, G., Huang, K. C., Xu, Z., Tzeng, J. Y., Conneely, K. N., Guan, W., Kang, J. & Li, Y., 2016 May 1, In : Genetic Epidemiology. 40, 4, p. 333-340 8 p.

Research output: Contribution to journalArticle

DNA Methylation
Methylation
DNA Fingerprinting
Acute Myeloid Leukemia
Epigenomics
5 Citations (Scopus)

Detection of gene-gene interactions using multistage sparse and low-rank regression

Hung, H., Lin, Y. T., Chen, P., Wang, C. C., Huang, S. Y. & Tzeng, J. Y., 2016 Mar 1, In : Biometrics. 72, 1, p. 85-94 10 p.

Research output: Contribution to journalArticle

Rank Regression
gene interaction
Screening
Genes
screening
3 Citations (Scopus)

Rare Variants Association Analysis in Large-Scale Sequencing Studies at the Single Locus Level

Jeng, X. J., Daye, Z. J., Lu, W. & Tzeng, J. Y., 2016 Jun, In : PLoS Computational Biology. 12, 6, e1004993.

Research output: Contribution to journalArticle

Open Access
Sequencing
Locus
loci
gene
Molecular Sequence Annotation
5 Citations (Scopus)

Testing and estimation in marker-set association study using semiparametric quantile regression kernel machine

Kong, D., Maity, A., Hsu, F. C. & Tzeng, J. Y., 2016 Jun 1, In : Biometrics. 72, 2, p. 364-371 8 p.

Research output: Contribution to journalArticle

Kernel Machines
Semiparametric Regression
Quantile Regression
Vitamins
Homocysteine
2015
5 Citations (Scopus)

A Fast Multiple-Kernel Method With Applications to Detect Gene-Environment Interaction

Marceau, R., Lu, W., Holloway, S., Sale, M. M., Worrall, B. B., Williams, S. R., Hsu, F. C. & Tzeng, J-Y., 2015 Sep 1, In : Genetic Epidemiology. 39, 6, p. 456-468 13 p.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Vitamins
Genes
Stroke
Homocysteine
3 Citations (Scopus)

A New Method for Detecting Associations with Rare Copy-Number Variants

The Swedish Schizophrenia Consortium, 2015 Jan 1, In : PLoS genetics. 11, 10, e1005403.

Research output: Contribution to journalArticle

Open Access
DNA Copy Number Variations
methodology
loci
behavior disorders
Gene Dosage

A penalized likelihood approach for investigating gene-drug interactions in pharmacogenetic studies

Neely, M. L., Bondell, H. D. & Tzeng, J-Y., 2015 Jun 1, In : Biometrics. 71, 2, p. 529-537 9 p.

Research output: Contribution to journalArticle

Drug interactions
pharmacogenomics
drug interactions
Penalized Likelihood
Drug Interactions
11 Citations (Scopus)

Assessing gene-environment interactions for common and rare variants with binary traits using gene-trait similarity regression

Zhao, G., Marceau, R., Zhang, D. & Tzeng, J. Y., 2015 Mar 1, In : Genetics. 199, 3, p. 695-710 16 p.

Research output: Contribution to journalArticle

Open Access
Gene-Environment Interaction
Genetic Heterogeneity
Genetic Models
Environmental Exposure
Genetic Markers
6 Citations (Scopus)

Complete effect-profile assessment in association studies with multiple genetic and multiple environmental factors

Wang, Z., Maity, A., Luo, Y., Neely, M. L. & Tzeng, J-Y., 2015 Feb 1, In : Genetic Epidemiology. 39, 2, p. 122-133 12 p.

Research output: Contribution to journalArticle

Gene-Environment Interaction
Genes
Genome-Wide Association Study
98 Citations (Scopus)

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

Cross-Disorder Working Group of the Psychiatric Genomics Consortium, 2015 Feb 5, In : American Journal of Human Genetics. 96, 2, p. 283-294 12 p.

Research output: Contribution to journalArticle

Open Access
Major Depressive Disorder
Bipolar Disorder
Psychiatry
Schizophrenia
Sample Size
5 Citations (Scopus)

Module-based association analysis for omics data with network structure

Wang, Z., Maity, A., Hsiao, C. K., Voora, D., Kaddurah-Daouk, R. & Tzeng, J. Y., 2015 Mar 30, In : PloS one. 10, 3, e0122309.

Research output: Contribution to journalArticle

Open Access
Information Services
Metabolites
data analysis
Genes
Topology
9 Citations (Scopus)

Proper Use of Allele-Specific Expression Improves Statistical Power for cis-eQTL Mapping with RNA-Seq Data

Hu, Y. J., Sun, W., Tzeng, J. Y. & Perou, C. M., 2015 Jul 3, In : Journal of the American Statistical Association. 110, 511, p. 962-974 13 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Statistical Power
Gene
Sequencing
Haplotype
361 Citations (Scopus)

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

The Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium & International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 2015 Feb 17, In : Nature Neuroscience. 18, 2, p. 199-209 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Histones
Psychiatry
Post-Synaptic Density
Genomics
21 Citations (Scopus)

The association between lower educational attainment and depression owing to shared genetic effects? Results in ∼25 000 subjects

Peyrot, W. J., Lee, S. H., Milaneschi, Y., Abdellaoui, A., Byrne, E. M., Esko, T., De Geus, E. J. C., Hemani, G., Hottenga, J. J., Kloiber, S., Levinson, D. F., Lucae, S., Martin, N. G., Medland, S. E., Metspalu, A., Milani, L., Noethen, M. M., Potash, J. B., Rietschel, M., Rietveld, C. A. & 300 others, Ripke, S., Shi, J., Willemsen, G., Zhu, Z., Boomsma, D. I., Wray, N. R., Penninx, B. W. J. H., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., Blackwood, D. H., Cichon, S., Heath, A. C., Holsboer, F., Madden, P. A., McGuffin, P., Muglia, P., Pergadia, M. L., Lin, D., Müller-Myhsok, B., Steinberg, S., Grabe, H. J., Lichtenstein, P., Magnusson, P., Perlis, R. H., Preisig, M., Smoller, J. W., Stefansson, K., Uher, R., Kutalik, Z., Tansey, K. E., Teumer, A., Viktorin, A., Barnes, M. R., Bettecken, T., Binder, E. B., Breuer, R., Castro, V. M., Churchill, S. E., Coryell, W. H., Craddock, N., Craig, I. W., Czamara, D., Degenhardt, F., Farmer, A. E., Fava, M., Frank, J., Gainer, V. S., Gallagher, P. J., Gordon, S. D., Goryachev, S., Gross, M., Guipponi, M., Henders, A. K., Herms, S., Hickie, I. B., Hoefels, S., Hoogendijk, W., Iosifescu, D. V., Ising, M., Jones, I., Jones, L., Jung-Ying, T., Knowles, J. A., Kohane, I. S., Kohli, M. A., Korszun, A., Landen, M., Lawson, W. B., Lewis, G., Macintyre, D., Maier, W., Mattheisen, M., McGrath, P. J., McIntosh, A., McLean, A., Middeldorp, C. M., Middleton, L., Montgomery, G. M., Murphy, S. N., Nauck, M., Nolen, W. A., Nyholt, D. R., O'Donovan, M., Oskarsson, H., Pedersen, N., Scheftner, W. A., Schulz, A., Schulze, T. G., Shyn, S. I., Sigurdsson, E., Slager, S. L., Smit, J. H., Stefansson, H., Steffens, M., Thorgeirsson, T., Tozzi, F., Treutlein, J., Uhr, M., Van Den Oord, E. J., Van Grootheest, G., Völzke, H., Weilburg, J. B., Willemsen, G., Zitman, F. G., Neale, B., Daly, M., Sullivan, P. F., Agrawal, A., Albrecht, E., Z Alizadeh, B., Allik, J., Amin, N., Attia, J. R., Bandinelli, S., Barnard, J., Bastardot, F., E Baumeister, S., Beauchamp, J., Benjamin, D. J., Benke, K. S., Bennett, D. A., Berger, K., Bielak, L. F., Bierut, L. J., Boatman, J. A., Boyle, P. A., Bültmann, U., Campbell, H., Cesarini, D., Chabris, C. F., Cherkas, L., Chung, M. K., Conley, D., Cucca, F., Davey-Smith, G., Davies, G., De Andrade, M., De Jager, P. L., De Leeuw, C., De Neve, J. E., Deary, I. J., Dedoussis, G. V., Deloukas, P., Derringer, J., Dimitriou, M., Eiriksdottir, G., Eklund, N., Elderson, M. F., Eriksson, J. G., Evans, D. S., Evans, D. M., Faul, J. D., Fehrmann, R., Ferrucci, L., Fischer, K., Franke, L., Garcia, M. E., Gieger, C., Gjessing, H. K., Groenen, P. J. F., Grönberg, H., Gudnason, V., Hägg, S., Hall, P., Harris, J. R., Harris, J. M., Harris, T. B., Hastie, N. D., Hayward, C., Heath, A. C., Hernandez, D. G., Hoffmann, W., Hofman, A., Hofman, A., Holle, R., Holliday, E. G., Holzapfel, C., Iacono, W. G., Ibrahim-Verbaas, C. A., Illig, T., Ingelsson, E., Jacobsson, B., Järvelin, M. R., Jhun, M. A., Johannesson, M., Joshi, P. K., Jugessur, A., Kaakinen, M., Kähönen, M., Kanoni, S., Kaprio, J., Kardia, S. L. R., Karjalainen, J., Kirkpatrick, R. M., Koellinger, P. D., Kolcic, I., Kowgier, M., Kristiansson, K., Krueger, R. F., Kutalik, Z., Lahti, J., Laibson, D., Latvala, A., Launer, L. J., Lawlor, D. A., Lethimäki, T., Li, J., Lichtenstein, P., Lichtner, P. K., Liewald, D. C., Lin, P., Lind, P. A., Liu, Y., Lohman, K., Loitfelder, M., Madden, P. A., Magnusson, P. K. E., Mäkinen, T. E., Vidal, P. M., Martin, N. W., Masala, M., McGue, M., McMahon, G., Meirelles, O., Meyer, M. N., Mielck, A., Milani, L., Miller, M. B., Montgomery, G. W., Mukherjee, S., Myhre, R., Nuotio, M. L., J Oldmeadow, C., Oostra, B. A., Palmer, L. J., Palotie, A., Perola, M., Petrovic, K. E., Peyser, P. A., Polašek, O., Posthuma, D., Preisig, M., Quaye, L., Räikkönen, K., Raitakari, O. T., Realo, A., Reinmaa, E., Rice, J. P., Ring, S. M., Ripatti, S., Rivadeneira, F., Rizzi, T. S., Rudan, I., Rustichini, A., Salomaa, V., Sarin, A. P., Schlessinger, D., Schmidt, H., Schmidt, R., Scott, R. J., Shakhbazov, K., Smith, A. V., Smith, J. A., Snieder, H., St Pourcain, B., Starr, J. M., Sul, J. H., Surakka, I., Svento, R., Tanaka, T., Terracciano, A., Teumer, A., Thurik, A. R., Tiemeier, H., Timpson, N. J., Uitterlinden, A. G., Van Der Loos, M. J. H. M., Van Duijn, C. M., Van Rooij, F. J. A., Van Wagoner, D. R., Vartiainen, E., Viikari, J., Visscher, P. M., Vitart, V., Vollenweider, P. K., Völzke, H., Vonk, J. M., Waeber, G., Weir, D. R., Wellmann, J., Westra, H. J., Wichmann, H. E., Widen, E., Wilson, J. F., Wright, A. F., Yang, J., Yu, L. & Zhao, W., 2015 Jun 26, In : Molecular Psychiatry. 20, 6, p. 735-743 9 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Depression
Single Nucleotide Polymorphism
Genomics
Mental Disorders
2014
4 Citations (Scopus)

Analysis of gene-gene interactions using gene-trait similarity regression

Wang, X., Epstein, M. P. & Tzeng, J-Y., 2014 Jan 1, In : Human Heredity. 78, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Open Access
Genes
Genome-Wide Association Study
Warfarin
Principal Component Analysis
Least-Squares Analysis
8 Citations (Scopus)

Gene-level pharmacogenetic analysis on survival outcomes using gene-trait similarity regression

Tzeng, J. Y., Lu, W. & Hsu, F. C., 2014 Jun, In : Annals of Applied Statistics. 8, 2, p. 1232-1255 24 p.

Research output: Contribution to journalArticle

Open Access
Stroke
Genes
Regression
Gene
Proportional Hazards Model
157 Citations (Scopus)

Heritability and genomics of gene expression in peripheral blood

Wright, F. A., Sullivan, P. F., Brooks, A. I., Zou, F., Sun, W., Xia, K., Madar, V., Jansen, R., Chung, W., Zhou, Y. H., Abdellaoui, A., Batista, S., Butler, C., Chen, G., Chen, T. H., D'Ambrosio, D., Gallins, P., Ha, M. J., Hottenga, J. J., Huang, S. & 19 others, Kattenberg, M., Kochar, J., Middeldorp, C. M., Qu, A., Shabalin, A., Tischfield, J., Todd, L., Tzeng, J-Y., Van Grootheest, G., Vink, J. M., Wang, Q., Wang, W., Wang, W., Willemsen, G., Smit, J. H., De Geus, E. J., Yin, Z., Penninx, B. W. J. H. & Boomsma, D. I., 2014 Jan 1, In : Nature Genetics. 46, 5, p. 430-437 8 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Genomics
Gene Expression
Genetic Transcription
Genes
4 Citations (Scopus)

Integrative gene set analysis of multi-platform data with sample heterogeneity

Hu, J. & Tzeng, J. Y., 2014 Jun 1, In : Bioinformatics. 30, 11, p. 1501-1507 7 p.

Research output: Contribution to journalArticle

Genes
Gene
Genomics
Mann-Whitney Statistic
Statistics
3 Citations (Scopus)

Pathway-Guided Identification of Gene-Gene Interactions

Wang, X., Zhang, D. & Tzeng, J. Y., 2014 Nov 1, In : Annals of Human Genetics. 78, 6, p. 478-491 14 p.

Research output: Contribution to journalArticle

Genes
Single Nucleotide Polymorphism
Sample Size
Weights and Measures
2013
618 Citations (Scopus)

A mega-Analysis of genome-wide association studies for major depressive disorder

Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, 2013 Apr 1, In : Molecular Psychiatry. 18, 4, p. 497-511 15 p.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
Major Depressive Disorder
Single Nucleotide Polymorphism
Bipolar Disorder
Genome
1120 Citations (Scopus)

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., Akil, H., Amin, F., Andreassen, O. A., Anjorin, A., Anney, R., Anttila, V., Arking, D. E., Asherson, P. & 350 others, Azevedo, M. H., Backlund, L., Badner, J. A., Bailey, A. J., Banaschewski, T., Barchas, J. D., Barnes, M. R., Barrett, T. B., Bass, N., Battaglia, A., Bauer, M., Bayés, M., Bellivier, F., Bergen, S. E., Berrettini, W., Betancur, C., Bettecken, T., Biederman, J., Binder, E. B., Black, D. W., Blackwood, D. H. R., Bloss, C. S., Boehnke, M., Boomsma, D. I., Breen, G., Breuer, R., Bruggeman, R., Cormican, P., Buccola, N. G., Buitelaar, J. K., Bunney, W. E., Buxbaum, J. D., Byerley, W. F., Byrne, E. M., Caesar, S., Cahn, W., Cantor, R. M., Casas, M., Chakravarti, A., Chambert, K., Choudhury, K., Cichon, S., Cloninger, C. R., Collier, D. A., Cook, E. H., Coon, H., Cormand, B., Corvin, A., Coryell, W. H., Craig, D. W., Craig, I. W., Crosbie, J., Cuccaro, M. L., Curtis, D., Czamara, D., Datta, S., Dawson, G., Day, R., De Geus, E. J., Degenhardt, F., Djurovic, S., Donohoe, G. J., Doyle, A. E., Duan, J., Dudbridge, F., Duketis, E., Ebstein, R. P., Edenberg, H. J., Elia, J., Ennis, S., Etain, B., Fanous, A., Farmer, A. E., Ferrier, I. N., Flickinger, M., Fombonne, E., Foroud, T., Frank, J., Franke, B., Fraser, C., Freedman, R., Freimer, N. B., Freitag, C. M., Friedl, M., Frisén, L., Gallagher, L., Gejman, P. V., Georgieva, L., Gershon, E. S., Geschwind, D. H., Giegling, I., Gill, M., Gordon, S. D., Gordon-Smith, K., Green, E. K., Greenwood, T. A., Grice, D. E., Gross, M., Grozeva, D., Guan, W., Gurling, H., De Haan, L., Haines, J. L., Hakonarson, H., Hallmayer, J., Hamilton, S. P., Hamshere, M. L., Hansen, T. F., Hartmann, A. M., Hautzinger, M., Heath, A. C., Henders, A. K., Herms, S., Hickie, I. B., Hipolito, M., Hoefels, S., Holmans, P. A., Holsboer, F., Hoogendijk, W. J., Hottenga, J. J., Hultman, C. M., Hus, V., Ingason, A., Ising, M., Jamain, S., Jones, E. G., Jones, I., Jones, L., Tzeng, J. Y., Kähler, A. K., Kahn, R. S., Kandaswamy, R., Keller, M. C., Kennedy, J. L., Kenny, E., Kent, L., Kim, Y., Kirov, G. K., Klauck, S. M., Klei, L., Knowles, J. A., Kohli, M. A., Koller, D. L., Konte, B., Korszun, A., Krabbendam, L., Krasucki, R., Kuntsi, J., Kwan, P., Landén, M., Långström, N., Lathrop, M., Lawrence, J., Lawson, W. B., Leboyer, M., Ledbetter, D. H., Lee, P. H., Lencz, T., Lesch, K. P., Levinson, D. F., Lewis, C. M., Li, J., Lichtenstein, P., Lieberman, J. A., Lin, D. Y., Linszen, D. H., Liu, C., Lohoff, F. W., Loo, S. K., Lord, C., Lowe, J. K., Lucae, S., Macintyre, D. J., Madden, P. A. F., Maestrini, E., Magnusson, P. K. E., Mahon, P. B., Maier, W., Malhotra, A. K., Mane, S. M., Martin, C. L., Martin, N. G., Mattheisen, M., Matthews, K., Mattingsdal, M., Mccarroll, S. A., Mcghee, K. A., Mcgough, J. J., Mcgrath, P. J., Mcguffin, P., Mcinnis, M. G., Mcintosh, A., Mckinney, R., Mclean, A. W., Mcmahon, F. J., Mcmahon, W. M., Mcquillin, A., Medeiros, H., Medland, S. E., Meier, S., Melle, I., Meng, F., Meyer, J., Middeldorp, C. M., Middleton, L., Milanova, V., Miranda, A., Monaco, A. P., Montgomery, G. W., Moran, J. L., Moreno-De-Luca, D., Morken, G., Morris, D. W., Morrow, E. M., Moskvina, V., Muglia, P., Mühleisen, T. W., Muir, W. J., Müller-Myhsok, B., Murtha, M., Myers, R. M., Myin-Germeys, I., Neale, M. C., Nelson, S. F., Nievergelt, C. M., Nikolov, I., Nimgaonkar, V., Nolen, W. A., Nöthen, M. M., Nurnberger, J. I., Nwulia, E. A., Nyholt, D. R., O'dushlaine, C., Oades, R. D., Olincy, A., Oliveira, G., Olsen, L., Ophoff, R. A., Osby, U., Owen, M. J., Palotie, A., Parr, J. R., Paterson, A. D., Pato, C. N., Pato, M. T., Penninx, B. W., Pergadia, M. L., Pericak-Vance, M. A., Pickard, B. S., Pimm, J., Piven, J., Posthuma, D., Potash, J. B., Poustka, F., Propping, P., Puri, V., Quested, D. J., Quinn, E. M., Ramos-Quiroga, J. A., Rasmussen, H. B., Raychaudhuri, S., Rehnström, K., Reif, A., Ribasés, M., Rice, J. P., Rietschel, M., Roeder, K., Roeyers, H., Rossin, L., Rothenberger, A., Rouleau, G., Ruderfer, D., Rujescu, D., Sanders, A. R., Sanders, S. J., Santangelo, S. L., Sergeant, J. A., Schachar, R., Schalling, M., Schatzberg, A. F., Scheftner, W. A., Schellenberg, G. D., Scherer, S. W., Schork, N. J., Schulze, T. G., Schumacher, J., Schwarz, M., Scolnick, E., Scott, L. J., Shi, J., Shilling, P. D., Shyn, S. I., Silverman, J. M., Slager, S. L., Smalley, S. L., Smit, J. H., Smith, E. N., Sonuga-Barke, E. J. S., St. Clair, D., State, M., Steffens, M., Steinhausen, H. C., Strauss, J. S., Strohmaier, J., Stroup, T. S., Sutcliffe, J. S., Szatmari, P., Szelinger, S., Thirumalai, S., Thompson, R. C., Todorov, A. A., Tozzi, F., Treutlein, J., Uhr, M., Van Den Oord, E. J. C. G., Van Grootheest, G., Van Os, J., Vicente, A. M., Vieland, V. J., Vincent, J. B., Visscher, P. M., Walsh, C. A., Wassink, T. H., Watson, S. J., Weissman, M. M., Werge, T., Wienker, T. F., Wijsman, E. M., Willemsen, G., Williams, N., Willsey, A. J., Witt, S. H., Xu, W., Young, A. H., Yu, T. W., Zammit, S., Zandi, P. P., Zhang, P., Zitman, F. G., Zöllner, S., Devlin, B., Kelsoe, J. R., Sklar, P., Daly, M. J., O'donovan, M. C., Craddock, N., Sullivan, P. F., Smoller, J. W., Kendler, K. S. & Wray, N. R., 2013 Sep 1, In : Nature Genetics. 45, 9, p. 984-994 11 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Single Nucleotide Polymorphism
Psychiatry
Schizophrenia
Bipolar Disorder
6 Citations (Scopus)

Statistical considerations in biosimilar assessment using biosimilarity index

Zhang, A., Tzeng, J. Y. & Chow, S. C., 2013, In : Journal of Bioequivalence and Bioavailability. 5, 5

Research output: Contribution to journalArticle

Open Access
Biosimilar Pharmaceuticals
Consumer Product Safety
Biological Products
Names
Pharmaceutical Preparations
2012
43 Citations (Scopus)

Don't give up on GWAS

on behalf of 96 Psychiatric Genetics Investigators, 2012 Jan 1, In : Molecular Psychiatry. 17, 1, p. 2-3 2 p.

Research output: Contribution to journalLetter

Open Access
46 Citations (Scopus)

Multivariate Phenotype Association Analysis by Marker-Set Kernel Machine Regression

Maity, A., Sullivan, P. F. & Tzeng, J. I., 2012 Nov 1, In : Genetic Epidemiology. 36, 7, p. 686-695 10 p.

Research output: Contribution to journalArticle

Phenotype
Antipsychotic Agents
Genes
Antibodies
9 Citations (Scopus)

On the aggregation of multimarker information for marker-set and sequencing data analysis: Genotype collapsing vs. Similarity collapsing

Pongpanich, M., Neely, M. L. & Tzeng, J. Y., 2012 Dec 1, In : Frontiers in Genetics. 2, JAN, Article 110.

Research output: Contribution to journalArticle

Open Access
Genotype
Genetic Markers
Signal-To-Noise Ratio
Noise
Phenotype
2011
3 Citations (Scopus)

Combining an Evolution-guided Clustering Algorithm and Haplotype-based LRT in Family Association Studies

Lee, M. H., Tzeng, J. Y., Huang, S. Y. & Hsiao, C. K., 2011 May 19, In : BMC Genetics. 12, 48.

Research output: Contribution to journalArticle

Open Access
Haplotypes
Cluster Analysis
Uncertainty
Single Nucleotide Polymorphism
Genotype
55 Citations (Scopus)

Studying gene and gene-environment effects of uncommon and common variants on continuous traits: A marker-set approach using gene-trait similarity regression

Tzeng, J. Y., Zhang, D., Pongpanich, M., Smith, C., McCarthy, M. I., Sale, M. M., Worrall, B. B., Hsu, F. C., Thomas, D. C. & Sullivan, P. F., 2011 Aug 12, In : American Journal of Human Genetics. 89, 2, p. 277-288 12 p.

Research output: Contribution to journalArticle

Open Access
Linkage Disequilibrium
Gene Frequency
Genes
Alleles
Genotype
2010
9 Citations (Scopus)

A comprehensive approach to haplotype-specific analysis by penalized likelihood

Tzeng, J-Y. & Bondell, H. D., 2010 Jan 1, In : European Journal of Human Genetics. 18, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

Open Access
Haplotypes
Genome
Weights and Measures
14 Citations (Scopus)

A quality control algorithm for filtering SNPs in genome-wide association studies

Pongpanich, M., Sullivan, P. F. & Tzeng, J. Y., 2010 May 25, In : Bioinformatics. 26, 14, p. 1731-1737 7 p., btq272.

Research output: Contribution to journalArticle

Single nucleotide Polymorphism
Genome-Wide Association Study
Nucleotides
Quality Control
Polymorphism
4 Citations (Scopus)

Evaluating haplotype effects in case-control studies via penalized-likelihood approaches: Prospective or retrospective analysis?

Koehler, M. L., Bondell, H. D. & Tzeng, J. Y., 2010 Dec 1, In : Genetic Epidemiology. 34, 8, p. 892-911 20 p.

Research output: Contribution to journalArticle

Haplotypes
Case-Control Studies
Genetic Models
Rheumatoid Arthritis
Phenotype
3 Citations (Scopus)

Haplotype-based pharmacogenetic analysis for longitudinal quantitative traits in the presence of dropout

Tzeng, J. Y., Lu, W., Farmen, M. W., Liu, Y. & Sullivan, P. F., 2010 Mar 1, In : Journal of Biopharmaceutical Statistics. 20, 2, p. 334-350 17 p.

Research output: Contribution to journalArticle

Haplotype
Drop out
Haplotypes
Interaction Effects
Missing at Random
2009
4 Citations (Scopus)

A regression-based association test for case-control studies that uses inferred ancestral haplotype similarity

Liu, Y., Li, Y. J., Satten, G. A., Allen, A. S. & Tzeng, J. Y., 2009 Aug 18, In : Annals of Human Genetics. 73, 5, p. 520-526 7 p.

Research output: Contribution to journalArticle

Haplotypes
Case-Control Studies
Single Nucleotide Polymorphism
Linkage Disequilibrium
Gene Frequency
5 Citations (Scopus)

Erratum: Genomewide association for schizophrenia in the CATIE study: Results of stage 1 (Molecular Psychiatry (2008) 13 (570-584) DOI: 10.1038/mp.2008.25)

Sullivan, P. F., Lin, D., Tzeng, J-Y., Van Den Oord, E., Perkins, D., Stroup, T. S., Wagner, M., Lee, S., Wright, F. A., Zou, F., Liu, W., Downing, A. M., Lieberman, J. & Close, S. L., 2009 Dec 1, In : Molecular Psychiatry. 14, 12, 1 p.

Research output: Contribution to journalComment/debate

Open Access
37 Citations (Scopus)

Gene-trait similarity regression for multimarker-based association analysis

Tzeng, J. Y., Zhang, D., Chang, S. M., Thomas, D. C. & Davidian, M., 2009 Sep 1, In : Biometrics. 65, 3, p. 822-832 11 p.

Research output: Contribution to journalArticle

Haplotypes
haplotypes
Genes
Regression
Haplotype
284 Citations (Scopus)

Genome-wide association for major depressive disorder: A possible role for the presynaptic protein piccolo

Sullivan, P. F., De Geus, E. J. C., Willemsen, G., James, M. R., Smit, J. H., Zandbelt, T., Arolt, V., Baune, B. T., Blackwood, D., Cichon, S., Coventry, W. L., Domschke, K., Farmer, A., Fava, M., Gordon, S. D., He, Q., Heath, A. C., Heutink, P., Holsboer, F., Hoogendijk, W. J. & 29 others, Hottenga, J. J., Hu, Y., Kohli, M., Lin, D., Lucae, S., MacIntyre, D. J., Maier, W., McGhee, K. A., McGuffin, P., Montgomery, G. W., Muir, W. J., Nolen, W. A., Nöthen, M. M., Perlis, R. H., Pirlo, K., Posthuma, D., Rietschel, M., Rizzu, P., Schosser, A., Smit, A. B., Smoller, J. W., Tzeng, J. Y., Van Dyck, R., Verhage, M., Zitman, F. G., Martin, N. G., Wray, N. R., Boomsma, D. I. & Penninx, B. W. J. H., 2009 Apr 1, In : Molecular Psychiatry. 14, 4, p. 359-375 17 p.

Research output: Contribution to journalArticle

Open Access
Major Depressive Disorder
Single Nucleotide Polymorphism
Genome
Proteins
Overlapping Genes
301 Citations (Scopus)

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

Cichon, S., Craddock, N., Daly, M., Faraone, S. V., Gejman, P. V., Kelsoe, J., Lehner, T., Levinson, D. F., Moran, A., Sklar, P., Sullivan, P. F., Anney, R., Gill, M., Corvin, A., Buitelaar, J., Franke, B., Elia, J., Hakonarson, H., Kent, L., McGough, J. & 103 others, Smalley, S., Ophoff, R., Mick, E., Santangelo, S., Ferreira, M., Purcell, S., Ruderfer, D., Smoller, J., Perlis, R., Neale, B., Stone, J., Nisenbaum, L., Thapar, A., Moskvina, V., Holmans, P., O'Donovan, M., Owen, M., Todd, R., Todorov, A., Rice, J., Devlin, B., Arking, D., Chakravarti, A., Potash, J. B., Pulver, A., Buxbaum, J. D., Cook, E., Peltonen, L., Suvisaari, J., Piven, J., Lin, D., Sullivan, P., Rouleau, G., Awadalla, P., Schellenberg, G., Scherer, S., Sutcliffe, J., Szatmari, P., Vieland, V., Andreassen, O. A., Frigessi, A., Blackwood, D., Muir, W., Boehnke, M., Burmeister, M., Flickinger, M., Guan, W., Li, J., Scott, L., Breuer, R., Rietschel, M., Schulze, T., Greenwood, T., Schork, N., Gurling, H., Muglia, P., Upmanyu, R., Tozzi, F., Noethen, M., Wienker, T., Steffens, M., Nurnberger, J., Kendler, K., Riley, B., van den Oord, E., Boomsma, D., de Geus, E., Hoogendijk, W., Penninx, B., Willemsen, A. H. M., Posthuma, D., Coryell, W., Hamilton, S., Kloiber, S., Lucae, S., Ripke, S., Lawson, W. B., Lewis, C., McGuffin, P., Martin, N., Wray, N., McGrath, P., Weissman, M. M., Offord, J., Scheftner, W. A., Slager, S., Fanous, A., Hultman, C., Kivikko, S., Laurent, C., Lencz, T., Malhotra, A., Mowry, B., Holliday, E., Sanders, A., Schwab, S., Wildenaver, D., St. Clair, D., Dudbridge, F., Pickering, E., Posthuma, D., Sebat, J. & Tzeng, J. Y., 2009 May 1, In : American Journal of Psychiatry. 166, 5, p. 540-556 17 p.

Research output: Contribution to journalReview article

Single Nucleotide Polymorphism
Psychiatry
History
Meta-Analysis
Linkage Disequilibrium
2008
280 Citations (Scopus)

Genomewide association for schizophrenia in the CATIE study: Results of stage 1

Sullivan, P. F., Lin, D., Tzeng, J. Y., Van Den Oord, E., Perkins, D., Stroup, T. S., Wagner, M., Lee, S., Wright, F. A., Zou, F., Liu, W., Downing, A. M., Lieberman, J. & Close, S. L., 2008 Jun, In : Molecular Psychiatry. 13, 6, p. 570-584 15 p.

Research output: Contribution to journalArticle

Open Access
Single Nucleotide Polymorphism
Schizophrenia
Phenotype
Diagnostic and Statistical Manual of Mental Disorders
Quality Control
2007
57 Citations (Scopus)

Haplotype-based association analysis via variance-components score test

Tzeng, J-Y. & Zhang, D., 2007 Jan 1, In : American Journal of Human Genetics. 81, 5, p. 927-938 12 p.

Research output: Contribution to journalArticle

Open Access
Haplotypes
Analysis of Variance
Likelihood Functions
Single Nucleotide Polymorphism
Cluster Analysis