• 4930 Citations
  • 37 h-Index
1992 …2020
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Personal profile

Education

  • 1993 PhD, Graduate Institute of Pharmacology ,National Taiwan University

Experience

  • 1991/08~1994/07 Teaching assistant, Department of Pharmacology College of Medicine, National Taiwan University, Taipei, Taiwan
  • 1994/08~1995/07 Lecturer, Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  • 1995/08~2000/07 Associate Professor, Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  • 1997/08~1998/04 Visiting Scholar, Department of Biology University of California at San Diego USA (Mentor: Mu-ming Poo, Ph.D.)
  • 2000/08 Professor, Department of Pharmacology, College of Medicine, National Cheng Kung University,Tainan, Taiwan
  • 2001/01- 2001/02 Visiting Professor, Department of Neurophysiology, University of Tokyo, Faculty of Medicine, Tokyo, Japan (Mentor: Tomoyuki Takahashi, Ph.D.)
  • 2002/08~2008/07 Chairman, Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  • 2005/08 Distinguished Professor, Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  • 2008/05~2010/07 Chairman, Institute of Bioinformatics, College of Bioscience and Biotechnology, National Cheng Kung University,Tainan, Taiwan
  • 2008/05~2010/07 Chairman, Institute of Biosignal Transduction, College of Bioscience and Biotechnology,National Cheng Kung University, Tainan, Taiwan
  • 2010/08~2013/07 Chairman, Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan
  • 2013/02~2013/07 Acting Dean, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwan
  • 2013/02~2017/07 Adjunct Professor, The Institute for Neural Regenerative Medicine, College of Medical Science and Biotechnology, Taipei Medical University,Taipei, Taiwan
  • 2013/08 Chair Professor, Department of Pharmacology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  • 2014/08~present Chairman, Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Research Interests

  • Elucidate the cellular and molecular mechanisms underlying the long-term synaptic plasticity, metaplasticity and structural plasticity
  • Study the cellular and molecular mechanisms involved in the generation of neurological disorders including stress-related psychiatric disorders, drug addiction and pain
  • Investigate the cellular and molecular mechanisms underlying the developmental processes and regulation of adult neurogenesis

Fingerprint Dive into the research topics where Kuei-Sen Hsu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Long-Term Potentiation Medicine & Life Sciences
Neuronal Plasticity Medicine & Life Sciences
Neurons Medicine & Life Sciences
Synapses Medicine & Life Sciences
Synaptic Transmission Medicine & Life Sciences
Excitatory Postsynaptic Potentials Medicine & Life Sciences
Hippocampus Medicine & Life Sciences
Long-Term Synaptic Depression Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1995 2020

Research Output 1992 2019

  • 4930 Citations
  • 37 h-Index
  • 133 Article
  • 8 Review article
  • 1 Chapter
  • 1 Comment/debate

Conditional deletion of CC2D1A reduces hippocampal synaptic plasticity and impairs cognitive function through RAC1 hyperactivation

Yang, C. Y., Yu, T. H., Wen, W. L., Ling, P. & Hsu, K. S., 2019 Jun 19, In : Journal of Neuroscience. 39, 25, p. 4959-4975 17 p.

Research output: Contribution to journalArticle

Neuronal Plasticity
Cognition
Neurons
Hippocampus
Sumoylation

Correction to: Rescue of Methyl-CpG Binding Protein 2 Dysfunction-induced Defects in Newborn Neurons by Pentobarbital (Neurotherapeutics, (2015), 12, 2, (477-490), 10.1007/s13311-015-0343-0)

Ma, D., Yoon, S. I., Yang, C. H., Marcy, G., Zhao, N., Leong, W. Y., Ganapathy, V., Han, J., Van Dongen, A. M. J., Hsu, K. S., Ming, G. L., Augustine, G. J. & Goh, E. L. K., 2019 Jan 1, In : Neurotherapeutics.

Research output: Contribution to journalComment/debate

Open Access
Methyl-CpG-Binding Protein 2
Pentobarbital
Publications
Neurons
2 Citations (Scopus)

Infantile Amnesia Is Related to Developmental Immaturity of the Maintenance Mechanisms for Long-Term Potentiation

Tsai, T. C., Huang, C. C. & Hsu, K-S., 2019 Feb 1, In : Molecular Neurobiology. 56, 2, p. 907-919 13 p.

Research output: Contribution to journalArticle

Amnesia
Long-Term Potentiation
Maintenance
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Long-Term Memory

Interplay between a Mental Disorder Risk Gene and Developmental Polarity Switch of GABA Action Leads to Excitation-Inhibition Imbalance

Kang, E., Song, J., Lin, Y., Park, J., Lee, J. H., Hussani, Q., Gu, Y., Ge, S., Li, W., Hsu, K. S., Berninger, B., Christian, K. M., Song, H. & Ming, G. L., 2019 Aug 6, In : Cell Reports. 28, 6, p. 1419-1428.e3

Research output: Contribution to journalArticle

Open Access
Developmental Genes
Mental Disorders
gamma-Aminobutyric Acid
Neurons
Parvalbumins
1 Citation (Scopus)

Perineuronal Nets Restrict the Induction of Long-Term Depression in the Mouse Hippocampal CA1 Region

Khoo, G. H., Lin, Y. T., Tsai, T. C. & Hsu, K-S., 2019 Sep 15, In : Molecular Neurobiology. 56, 9, p. 6436-6450 15 p.

Research output: Contribution to journalArticle

Hippocampal CA1 Region
Depression
Parvalbumins
Neuronal Plasticity
Interneurons

Thesis

Impact of prenatal stress on hippocampal neuroplasticity

Author: 哲銘, 葉., 2014 Aug 1

Supervisor: Hsu, K. (Supervisor)

Student thesis: Doctoral Thesis

Neural circuitries and neurobiological mechanisms relevant to stress resilience

Author: 迪侖, 周., 2016 Aug 3

Supervisor: Hsu, K. (Supervisor)

Student thesis: Doctoral Thesis

Perineuronal nets restrict the induction of long-term depression in the mouse hippocampal CA1 region

Author: 原富, 邱., 2018 Aug 13

Supervisor: Hsu, K. (Supervisor)

Student thesis: Master's Thesis

Role of NADPH oxidases in sepsis-induced changes in seizure susceptibility and cognitive function

Author: 婉愉, 黃., 2019

Supervisor: Hsu, K. (Supervisor)

Student thesis: Doctoral Thesis

The role of oxytocin in the hippocampal synaptic plasticity and adult neurogenesis

Author: 郁婷, 林., 2016 Jul 5

Supervisor: Hsu, K. (Supervisor)

Student thesis: Doctoral Thesis