• 890 Citations
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19972020
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Research Output 1997 2019

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Article
2019

Age-Dependent Relationship Between Plasma Aβ40 and Aβ42 and Total Tau Levels in Cognitively Normal Subjects

Lue, L. F., Pai, M. C., Chen, T. F., Hu, C. J., Huang, L. K., Lin, W. C., Wu, C. C., Jeng, J. S., Blennow, K., Sabbagh, M. N., Yan, S. H., Wang, P. N., Yang, S. Y., Hatsuta, H., Morimoto, S., Takeda, A., Itoh, Y., Liu, J., Xie, H. & Chiu, M. J., 2019 Sep 3, In : Frontiers in Aging Neuroscience. 11, 222.

Research output: Contribution to journalArticle

Open Access
Biomarkers
Age Groups
Alzheimer Disease
Neurofibrillary Tangles
Amyloid Plaques
2 Citations (Scopus)
Exercise
Interleukin-15
Brain-Derived Neurotrophic Factor
Insulin-Like Growth Factor I
Cytokines
1 Citation (Scopus)

Factors Influencing Family Surrogates’ Intention with Regard to Do-Not-Resuscitate Directive for Patients with Dementia

Fang, Y. C., Pai, M-C., Wang, L-C., Yang, Y. P., Li, C-Y., Lee, F. P. & Wang, J-J., 2019 Jan 1, In : Clinical Gerontologist. 42, 5, p. 495-503 9 p.

Research output: Contribution to journalArticle

dementia
Dementia
Taiwan
Musculoskeletal Diseases
spouse

Predictors of caregiver burden and care costs for older persons with dementia in Taiwan

Ku, L-J. E., Chang, S-M., Pai, M-C. & Hsieh, H. M., 2019 Jun 1, In : International Psychogeriatrics. 31, 6, p. 885-894 10 p.

Research output: Contribution to journalArticle

Taiwan
Caregivers
Dementia
Costs and Cost Analysis
Interviews

The Role of Methylated Circulating Nucleic Acids as a Potential Biomarker in Alzheimer’s Disease

Pai, M-C., Kuo, Y-M., Wang, I. F., Chiang, P-M. & Tsai, K-J., 2019 Apr 1, In : Molecular Neurobiology. 56, 4, p. 2440-2449 10 p.

Research output: Contribution to journalArticle

Nucleic Acids
Alzheimer Disease
Biomarkers
Amyloid
Relapsing-Remitting Multiple Sclerosis
2018
7 Citations (Scopus)
Exercise
Insulin-Like Growth Factor I
Cognitive Dysfunction
Brain-Derived Neurotrophic Factor
Vascular Endothelial Growth Factor A

Development and validation of a dementia screening tool for primary care in Taiwan: Brain Health Test

Tsai, P. H., Liu, J. L., Lin, K. N., Chang, C. C., Pai, M-C., Wang, W. F., Huang, J. P., Hwang, T. J. & Wang, P. N., 2018 Apr 1, In : PloS one. 13, 4, e0196214.

Research output: Contribution to journalArticle

dementia
Taiwan
Dementia
Brain
Primary Health Care
1 Citation (Scopus)

Predictive Models for Evaluating Cognitive Ability in Dementia Diagnosis Applications Based on Inertia- and Gait-Related Parameters

Wang, W. H., Hsu, Y. L., Chung, P-C. & Pai, M-C., 2018 Apr 15, In : IEEE Sensors Journal. 18, 8, p. 3338-3350 13 p.

Research output: Contribution to journalArticle

gait
inertia
Feedforward neural networks
floating
Feature extraction
2017

Long-term care services use and reasons for non-use by elders with dementia and their families

Shih, P. Y., Ku, L-J. E., Pai, M-C. & Liu, L-F., 2017 Aug 1, In : Taiwan Journal of Public Health. 36, 4, p. 375-385 11 p.

Research output: Contribution to journalArticle

Long-Term Care
Dementia
Caregivers
Telephone
Logistic Models
11 Citations (Scopus)
dementia
Caregivers
Statistical Factor Analysis
caregiver
Dementia
4 Citations (Scopus)

Sundown Syndrome, Sleep Quality, and Walking Among Community-Dwelling People With Alzheimer Disease

Shih, Y. H., Wang, J-J., Shih, Y. H., Pai, M-C. & Huang, Y. C., 2017 May 1, In : Journal of the American Medical Directors Association. 18, 5, p. 396-401 6 p.

Research output: Contribution to journalArticle

Somnambulism
Independent Living
Alzheimer Disease
Sleep
Walking
2 Citations (Scopus)

Visual hallucinations in Alzheimer’s disease is significantly associated with clinical diagnostic features of dementia with Lewy bodies

Chiu, P. Y., Hsu, M. H., Wang, C. W., Tsai, C. T. & Pai, M. C., 2017 Oct, In : PloS one. 12, 10, e0186886.

Research output: Contribution to journalArticle

Lewy Body Disease
Eye movements
dementia
Hallucinations
Alzheimer disease
2016
11 Citations (Scopus)

Alzheimer's disease with cerebrovascular disease: current status in the Asia–Pacific region

Chen, C., Homma, A., Mok, V. C. T., Krishnamoorthy, E., Alladi, S., Meguro, K., Abe, K., Dominguez, J., Marasigan, S., Kandiah, N., Kim, S. Y., Lee, D. Y., De Silva, H. A., Yang, Y. H., Pai, M-C., Senanarong, V. & Dash, A., 2016 Oct 1, In : Journal of Internal Medicine. 280, 4, p. 359-374 16 p.

Research output: Contribution to journalArticle

Cerebrovascular Disorders
Alzheimer Disease
Dementia
Behavioral Symptoms
Neuroimaging
6 Citations (Scopus)

Cross-cultural study of caregiver burden for Alzheimer's disease in Japan and Taiwan: Result from Dementia Research in Kumamoto and Tainan (DeReKaT)

Matsushita, M., Pai, M-C., Jhou, C. Y., Koyama, A. & Ikeda, M., 2016 Jul 1, In : International Psychogeriatrics. 28, 7, p. 1125-1132 8 p.

Research output: Contribution to journalArticle

Taiwan
Caregivers
Dementia
Japan
Alzheimer Disease
17 Citations (Scopus)
dementia
economic impact
Taiwan
disease severity
Dementia
7 Citations (Scopus)

Real-world evaluation of compliance and preference in Alzheimer’s disease treatment: An observational study in Taiwan

Lai, T. H., Wang, W. F., Yip, B. S., Yang, Y. W., Peng, G. S., Tsai, S. J., Liao, Y. C. & Pai, M-C., 2016 Mar 30, In : Patient Preference and Adherence. 10, p. 383-390 8 p.

Research output: Contribution to journalArticle

Rivastigmine
Taiwan
dementia
Compliance
Observational Studies
8 Citations (Scopus)

The incidence and recurrence of getting lost in community-dwelling people with Alzheimer's disease: A two and a half-year follow-up

Pai, M-C. & Lee, C. C., 2016 May 1, In : PloS one. 11, 5, e0155480.

Research output: Contribution to journalArticle

Independent Living
Alzheimer disease
Aptitude
Alzheimer Disease
caregivers
6 Citations (Scopus)

The Role of Physical Fitness in the Neurocognitive Performance of Task Switching in Older Persons with Mild Cognitive Impairment

Tsai, C-L., Pai, M-C., Ukropec, J. & Ukropcová, B., 2016 Jun 22, In : Journal of Alzheimer's Disease. 53, 1, p. 143-159 17 p., JAD151093.

Research output: Contribution to journalArticle

Physical Fitness
Task Performance and Analysis
Cognitive Dysfunction
Evoked Potentials
Reaction Time
2015
4 Citations (Scopus)

Real-world evaluation of compliance and preference in Alzheimer’s disease treatment

Pai, M-C., Aref, H., Bassil, N., Kandiah, N., Lee, J. H., Srinivasan, A. V., diTommaso, S. & Yuksel, O., 2015 Nov 3, In : Clinical Interventions in Aging. 10, p. 1779-1788 10 p.

Research output: Contribution to journalArticle

Compliance
Alzheimer Disease
Rivastigmine
Caregivers
Patient Compliance
1 Citation (Scopus)
Alzheimer Disease
Caregivers
Interviews
Psychology
Patient-Centered Care
2014
21 Citations (Scopus)

Apolipoprotein C-III is an amyloid-β-binding protein and an early marker for Alzheimer's disease

Shih, Y. H., Tsai, K. J., Lee, C. W., Shiesh, S. C., Chen, W. T., Pai, M. C. & Kuo, Y. M., 2014 Jan 1, In : Journal of Alzheimer's disease : JAD. 41, 3, p. 855-865 11 p.

Research output: Contribution to journalArticle

Apolipoprotein C-III
Amyloidogenic Proteins
Carrier Proteins
Alzheimer Disease
Apolipoprotein A-I
44 Citations (Scopus)

Gait and balance analysis for patients with Alzheimer's disease using an inertial-sensor-based wearable instrument

Hsu, Y. L., Chung, P-C., Wang, W. H., Pai, M-C., Wang, C. Y., Lin, C. W., Wu, H. L. & Wang, J-S., 2014 Nov 1, In : IEEE Journal of Biomedical and Health Informatics. 18, 6, p. 1822-1830 9 p., 6824156.

Research output: Contribution to journalArticle

Gait
Alzheimer Disease
Sensors
Aptitude
Decomposition
39 Citations (Scopus)
Prefrontal Cortex
Short-Term Memory
Reaction Time
Aptitude
Transcranial Direct Current Stimulation
3 Citations (Scopus)
Nootropic Agents
Taiwan
Cholinesterase Inhibitors
Health Care Costs
Dementia

Use of ICT in dementia from assessment to intervention: The Taiwanese contribution to the SafEE project

Wang, W. H., Chung, P-C., Hsu, Y. L. & Pai, M-C., 2014 Jan 1, In : Gerontechnology. 13, 2, p. 82-83 2 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
Gyroscopes
Gait
Equipment and Supplies
2013
10 Citations (Scopus)
Azepines
Amyloid Precursor Protein Secretases
Psoriasis
Alanine
Alzheimer Disease
12 Citations (Scopus)

Impaired translation of spatial representation in young onset Alzheimer's disease patients

Pai, M-C. & Yang, Y. C., 2013, In : Current Alzheimer Research. 10, 1, p. 95-103 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Aptitude
Age of Onset
Spatial Navigation
16 Citations (Scopus)

Montreal Cognitive Assessment and Mini-Mental State Examination performance in patients with mild-to-moderate dementia with Lewy bodies, Alzheimer's disease, and normal participants in Taiwan

Wang, C. S. M., Pai, M-C., Chen, P. L., Hou, N. T., Chien, P. F. & Huang, Y. C., 2013 Nov 1, In : International Psychogeriatrics. 25, 11, p. 1839-1848 10 p.

Research output: Contribution to journalArticle

Lewy Body Disease
Taiwan
Dementia
Alzheimer Disease
Lewy Bodies
2012
10 Citations (Scopus)

Development of a questionnaire on everyday navigational ability to assess topographical disorientation in Alzheimer's disease

Pai, M-C., Lee, C. C., Yang, Y. C., Lee, Y. T., Chen, K. C., Lin, S. H., Jheng, S. S., Sun, P. W. & Cheng, P. J., 2012 Jan 1, In : American Journal of Alzheimer's Disease and other Dementias. 27, 1, p. 65-72 8 p.

Research output: Contribution to journalArticle

Confusion
Aptitude
Alzheimer Disease
Caregivers
Agnosia

Future memory (過去的記憶 未來的想像)

Pai, M-C., 2012 Jul, In : 科學發展.

Research output: Contribution to journalArticle

Reach patient’s heart (Chinese).

Pai, M-C., 2012, In : Journal of Taiwan Medical Association.

Research output: Contribution to journalArticle

9 Citations (Scopus)
Alzheimer Disease
Aptitude
Visual Acuity
Recognition (Psychology)
Efficiency
1 Citation (Scopus)

Two gloves and one sock syndrome after a pontine hemorrhage

Wu, Y-J. & Pai, M-C., 2012 Jul 1, In : Neurologist. 18, 4, p. 196-198 3 p.

Research output: Contribution to journalArticle

Paresthesia
Hand
Hemorrhage
Brain Stem
Leg
3 Citations (Scopus)

Validation of the route map recall test for getting lost behavior in Alzheimer's disease patients

Wang, T-Y., Kuo, Y. C., Ma, H-I., Lee, C. C. & Pai, M-C., 2012 Nov 1, In : Archives of Clinical Neuropsychology. 27, 7, p. 781-789 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Trail Making Test
Sensitivity and Specificity
Psychometrics
Reproducibility of Results
2011
3 Citations (Scopus)

Topographical disorientation in a patient with late-onset blindness with multiple acute ischemic brain lesions

Han, Y. H., Pai, M-C. & Hong, C. T., 2011 Feb 1, In : Journal of Clinical Neuroscience. 18, 2, p. 283-285 3 p.

Research output: Contribution to journalArticle

Confusion
Blindness
Occipital Lobe
Parietal Lobe
Brain
21 Citations (Scopus)
Evoked Potentials
Alzheimer Disease
Aptitude
Recognition (Psychology)
Single photon emission computed tomography
Normal Distribution
Normal distribution
Single-Photon Emission-Computed Tomography
Alzheimer Disease

Navigational impairment after brain damage.

Pai, M-C., 2010 Jun, In : Science Development.

Research output: Contribution to journalArticle

2009
27 Citations (Scopus)

Cognitive map in patients with mild Alzheimer's disease: A computer-generated arena study

Jheng, S. S. & Pai, M-C., 2009 Jun 8, In : Behavioural Brain Research. 200, 1, p. 42-47 6 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Hand
Learning
Education
Aptitude
2008
1 Citation (Scopus)

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

Sung, P-S. & Pai, M-C., 2008 Dec, In : Acta Neurologica Taiwanica. 17, 4, p. 295-296 2 p.

Research output: Contribution to journalArticle

CADASIL
Notch Receptors
Dominant Genes
Vascular Dementia
Cerebral Infarction
20 Citations (Scopus)

Cognitive function and blood methylmercury in adults living near a deserted chloralkali factory

Chang, J. W., Pai, M-C., Chen, H-L., Guo, H-R., Su, H-J. & Lee, C-C., 2008 Nov 1, In : Environmental Research. 108, 3, p. 334-339 6 p.

Research output: Contribution to journalArticle

methylmercury
Cognition
Industrial plants
Blood
blood
23 Citations (Scopus)

Comparative cognitive effects of levetiracetam and topiramate in intractable epilepsy

Huang, C-W., Pai, M-C. & Tsai, J. J., 2008 Oct 1, In : Psychiatry and Clinical Neurosciences. 62, 5, p. 548-553 6 p.

Research output: Contribution to journalArticle

etiracetam
Cognition
Pharmaceutical Preparations
Aptitude
Epilepsy
1 Citation (Scopus)

Topographical disorientation: viewpoint from behavioral neurology.

Pai, M-C., 2008 Dec, In : Acta Neurologica Taiwanica.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Transient amnesia in a patient with left temporal tumor: Symptomatic transient global amnesia or an epileptic amnesia?

Huang, C. F. & Pai, M-C., 2008 May 1, In : Neurologist. 14, 3, p. 196-200 5 p.

Research output: Contribution to journalArticle

Transient Global Amnesia
Amnesia
Neoplasms
Migraine Disorders
Anterograde Amnesia
2007
30 Citations (Scopus)

Genotype and plasma concentration of cystatin C in patients with late-onset Alzheimer disease

Chuo, L. J., Sheu, W. H. H., Pai, M-C. & Kuo, Y-M., 2007 Mar 1, In : Dementia and Geriatric Cognitive Disorders. 23, 4, p. 251-257 7 p.

Research output: Contribution to journalArticle

Cystatin C
Alzheimer Disease
Genotype
Alleles
Control Groups
1 Citation (Scopus)

Late onset buerger's disease with multiple cerebral infarcts

Huang, W-W., Wu, C-H., Li, C. F. & Pai, M-C., 2007 Mar 1, In : Tzu Chi Medical Journal. 19, 1, p. 28-31 4 p.

Research output: Contribution to journalArticle

Thromboangiitis Obliterans
Cyanosis
Hypesthesia
Ulnar Artery
Hemianopsia
2006
4 Citations (Scopus)
Taiwan
Dementia
Cognition
Aptitude
Decision Making