• 3584 Citations
  • 30 h-Index
1982 …2019
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Personal profile

Education

  • 美國貝勒醫學院生化系博士

Research Interests

  • DNA疫苗
  • 基因治療
  • 致癌基因
  • 抑癌基因
  • MST3

Fingerprint Dive into the research topics where Ming-Derg Lai is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Neoplasms Medicine & Life Sciences
DNA Vaccines Medicine & Life Sciences
Urinary Bladder Neoplasms Medicine & Life Sciences
Hepatitis B virus Medicine & Life Sciences
Endoplasmic Reticulum Stress Medicine & Life Sciences
DNA Medicine & Life Sciences
Small Interfering RNA Medicine & Life Sciences
Indoleamine-Pyrrole 2,3,-Dioxygenase Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1995 2018

Research Output 1982 2019

  • 3584 Citations
  • 30 h-Index
  • 127 Article
  • 3 Review article
  • 3 Patent
  • 1 Chapter
1 Citation (Scopus)

Cancer immunotherapy: Silencing intracellular negative immune regulators of dendritic cells

Liu, Y. H., Yeh, I. J., Lai, M. D., Liu, K. T., Kuo, P. L. & Yen, M. C., 2019 Jan 1, In : Cancers. 11, 1, 108.

Research output: Contribution to journalReview article

Open Access
Immunotherapy
Dendritic Cells
Small Interfering RNA
Neoplasms
DNA Vaccines
4 Citations (Scopus)

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

Wang, S. M., Lim, S. W., Wang, Y. H., Lin, H. Y., Lai, M. D., Ko, C. Y. & Wang, Y-M., 2018 Jun, In : Redox Biology. 16, p. 104-112 9 p.

Research output: Contribution to journalArticle

CCAAT-Enhancer-Binding Protein-delta
Oxidative stress
Reactive Oxygen Species
Astrocytes
Oxidative Stress
1 Citation (Scopus)

Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation

Weng, T. Y., Wu, H. F., Li, C. Y., Hung, Y. H., Chang, Y. W., Chen, Y. L., Hsu, H. P., Chen, Y. H., Wang, C. Y., Chang, J. Y. & Lai, M. D., 2018 Dec 1, In : Scientific reports. 8, 1, 8216.

Research output: Contribution to journalArticle

Mutation
Neoplasms
B-Lymphocytes
Lung
Cytokines
6 Citations (Scopus)

Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells

Sun, Z., Wang, C. Y., Lawson, D. A., Kwek, S., Velozo, H. G., Owyong, M., Lai, M. D., Fong, L., Wilson, M., Su, H., Werb, Z. & Cooke, D. L., 2018 Jan 1, In : Oncotarget. 9, 13, p. 10945-10961 17 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Transcriptome
Endothelial Cells
Breast Neoplasms
Genes
7 Citations (Scopus)

Argininosuccinate lyase interacts with cyclin A2 in cytoplasm and modulates growth of liver tumor cells

Hung, Y. H., Huang, H. L., Chen, W. C., Yen, M. C., Cho, C. Y., Weng, T. Y., Wang, C. Y., Chen, Y. L., Chen, L. T. & Lai, M. D., 2017 Feb, In : Oncology Reports. 37, 2, p. 969-978 10 p.

Research output: Contribution to journalArticle

Cyclin A2
Argininosuccinate Lyase
Cytoplasm
Liver
Growth

Thesis

Study of MicroRNA Processing Machinery on Drug-resistant Colon Cancer

Author: 煥文, 陳., 2018 Jul 20

Supervisor: Lai, M. (Supervisor)

Student thesis: Master's Thesis

The Contribution of Altered Metabolism in Lipid and Amino Acid to Cancer Development

Author: 妤萱, 洪., 2017 Jul 3

Supervisor: Lai, M. (Supervisor)

Student thesis: Doctoral Thesis

The Role of CD34 Family Protein in Breast Cancer

Author: 苡議, 林., 2018 Jul 13

Supervisor: Lai, M. (Supervisor)

Student thesis: Master's Thesis

The Role of Endoplasmic Reticulum Stress at the Rostral Ventrolateral Medulla in Neurogenic Hypertension

Author: 詠梅, 趙., 2014 Jan 7

Supervisor: Lai, M. (Supervisor)

Student thesis: Doctoral Thesis

探討星狀膠質細胞CEBPD 在神經性發炎中參與抗細胞凋亡及活性氧之形成

Author: 紹銘, 王., 2016 Nov 15

Supervisor: Lai, M. (Supervisor)

Student thesis: Doctoral Thesis