Nan-Shan Chang

Professor

  • 2327 Citations
  • 26 h-Index
1985 …2018
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Personal profile

Education

  • 1984 PhD, Immunology,Medical Univ. of S. Carolina Charleston, S. Carolina.

Research Interests

  • Apoptosis Signaling
  • Signal transduction

Experience

  • 1977 winter Research Assistant, Tungkang Marine Laboratory, Tungkang, Taiwan
  • 1978/7~1980/7 Teaching Assistant, National Taiwan Normal Univ., Department of Biology
  • 1982 Teaching Assistant of Dental Microbiology for one semester, Medical Univ. of South Carolina, Dept. of Basic & Clinical Immunology & Microbiology
  • 1985/1~1986/12 Post Doctoral Fellow, The Samuel Roberts Noble Foundation, Immunology Section
  • 1987/1~1989/6 Instructor, University of Massachusetts Medical Center, Department of Biochemistry
  • 1989/09~ Adjunct Associate Professor, Medical University of South Carolina, College of Dental Medicine
  • 1989/7~1995/6 Assistant Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility
  • 1991/01~ Consultant, GlycoMed Research Incorporated, Hastings on Hudson, NY
  • 1995/7~2005/12 Associate Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility
  • 1996/3~2006/8 Adjunct Research Associate Professor, Upstate Medical University at Syracuse, Department of Immunology and Microbiology & Integrated Medicine
  • 2006/11~ Distinguished Professor,Institute of Molecular Medicine, College of Medicine, National Cheng Kung University
  • 2006/11~ Professor, Institute of Molecular Medicine, College of Medicine, National Cheng Kung University
  • 2010/08~2016/07 Director, Institute of Molecular Medicine, College of Medicine, National Cheng Kung University

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  • 2 Similar Profiles
Apoptosis Medicine & Life Sciences
Oxidoreductases Medicine & Life Sciences
Tumor Necrosis Factor-alpha Medicine & Life Sciences
Hyaluronoglucosaminidase Medicine & Life Sciences
Cell Death Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Cell death Chemical Compounds
Transforming Growth Factors Medicine & Life Sciences

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Projects 2007 2018

WWOX磷酸化控制免疫細胞成熟

Chang, N.

17-08-0118-07-31

Project: Research projectResearch

WWOX磷酸化和免疫調節

Chang, N.

16-08-0117-07-31

Project: Research projectResearch

抑制 WWOX 蛋白激活並誘導在體內生成幹細胞

Chang, N.

15-08-0116-07-31

Project: Research projectResearch

Research Output 1985 2018

Fast and improved bioimaging via temporal focusing multiphoton excitation microscopy with binary digital-micromirror-device holography

Sie, Y. D., Chang, C. Y., Lin, C. Y., Chang, N-S., Campagnola, P. J. & Chen, S. J., 2018 Jan 1, In : Journal of Biomedical Optics. 23, 11, 116502.

Research output: Contribution to journalArticle

Digital devices
Ultrafast lasers
Fluorescence microscopy
Holography
Medical imaging

Natural zeolite for adsorbing and release of functional materials

Hovhannisyan, V. A., Dong, C. Y., Lai, F. J., Chang, N-S. & Chen, S. J., 2018 Sep 1, In : Journal of Biomedical Optics. 23, 9, 091411.

Research output: Contribution to journalArticle

Zeolites
Functional materials
Spectrometry
Microscopic examination
drugs
1 Citations

Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events

Huang, S. S. & Chang, N-S., 2018 Jan 1, In : Experimental Biology and Medicine. 243, 2, p. 137-147 11 p.

Research output: Contribution to journalReview article

Phosphorylation
Tumors
Disease Progression
Neoplasms
Alzheimer Disease

WWOX phosphorylation, signaling, and role in neurodegeneration

Liu, C. C., Ho, P. C., Lee, I. T., Chen, Y. A., Chu, C-H., Teng, C. C., Wu, S-N., Sze, C-I., Chiang, M. F. & Chang, N-S., 2018 Aug 15, In : Frontiers in Neuroscience. 12, AUG, 563.

Research output: Contribution to journalReview article

Amyloid
Phosphorylation
Genetic Suppression
Proteins
Alcohol Dehydrogenase
3 Citations

Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed

Hsu, L-J., Hong, Q., Chen, S. T., Kuo, H. L., Schultz, L., Heath, J., Lin, S. R., Lee, M. H., Li, D. Z., Li, Z. L., Cheng, H. C., Armand, G. & Chang, N-S., 2017 Jan 1, In : Oncotarget. 8, 12, p. 19137-19155 19 p.

Research output: Contribution to journalArticle

Hyaluronic Acid
Cell Death
Transforming Growth Factor beta
Hyaluronoglucosaminidase
Membranes