Nan-Shan Chang

Professor

  • 2499 Citations
  • 27 h-Index
1985 …2020
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Personal profile

Education

  • 1984 PhD, Immunology,Medical Univ. of S. Carolina Charleston, S. Carolina.

Research Interests

  • Apoptosis Signaling
  • Signal transduction

Experience

  • 1977 winter Research Assistant, Tungkang Marine Laboratory, Tungkang, Taiwan
  • 1978/7~1980/7 Teaching Assistant, National Taiwan Normal Univ., Department of Biology
  • 1982 Teaching Assistant of Dental Microbiology for one semester, Medical Univ. of South Carolina, Dept. of Basic & Clinical Immunology & Microbiology
  • 1985/1~1986/12 Post Doctoral Fellow, The Samuel Roberts Noble Foundation, Immunology Section
  • 1987/1~1989/6 Instructor, University of Massachusetts Medical Center, Department of Biochemistry
  • 1989/09~ Adjunct Associate Professor, Medical University of South Carolina, College of Dental Medicine
  • 1989/7~1995/6 Assistant Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility
  • 1991/01~ Consultant, GlycoMed Research Incorporated, Hastings on Hudson, NY
  • 1995/7~2005/12 Associate Scientist and Laboratory Director, Guthrie Research Institute, Laboratory of Molecular Immunology & Protein/Peptide Microsequencing Core Facility
  • 1996/3~2006/8 Adjunct Research Associate Professor, Upstate Medical University at Syracuse, Department of Immunology and Microbiology & Integrated Medicine
  • 2006/11~ Distinguished Professor,Institute of Molecular Medicine, College of Medicine, National Cheng Kung University
  • 2006/11~ Professor, Institute of Molecular Medicine, College of Medicine, National Cheng Kung University
  • 2010/08~2016/07 Director, Institute of Molecular Medicine, College of Medicine, National Cheng Kung University

Fingerprint Dive into the research topics where Nan-Shan Chang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Apoptosis Medicine & Life Sciences
Oxidoreductases Medicine & Life Sciences
Tumor Necrosis Factor-alpha Medicine & Life Sciences
Hyaluronoglucosaminidase Medicine & Life Sciences
Cell Death Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Proteins Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2007 2020

Research Output 1985 2019

A p53/TIAF1/WWOX triad exerts cancer suppression but may cause brain protein aggregation due to p53/WWOX functional antagonism

Chou, P. Y., Lin, S. R., Lee, M. H., Schultz, L., Sze, C-I. & Chang, N-S., 2019 Jul 17, In : Cell Communication and Signaling. 17, 1, 76.

Research output: Contribution to journalArticle

Open Access
Brain
Agglomeration
Chemical activation
Apoptosis
Cell Movement

Strategies by which WWOX-deficient metastatic cancer cells utilize to survive via dodging, compromising, and causing damage to WWOX-positive normal microenvironment

Chou, P. Y., Lai, F. J., Chen, Y. A., Sie, Y. D., Kuo, H. L., Su, W. P., Wu, C. Y., Liu, T. Y., Wen, K. Y., Hsu, L-J., Sze, C-I. & Chang, N-S., 2019 Dec 1, In : Cell Death Discovery. 5, 1, 97.

Research output: Contribution to journalArticle

Open Access
Neoplasms
Cellular Microenvironment
Hyaluronoglucosaminidase
Growth
Neoplasm Metastasis
2 Citations (Scopus)

WW domain-containing proteins YAP and TAZ in the hippo pathway as key regulators in stemness maintenance, tissue homeostasis, and tumorigenesis

Chen, Y. A., Lu, C. Y., Cheng, T. Y., Pan, S. H., Chen, H. F. & Chang, N-S., 2019 Jan 1, In : Frontiers in Oncology. 9, FEB, 60.

Research output: Contribution to journalReview article

Open Access
Carcinogenesis
Homeostasis
Stem Cells
Maintenance
Regeneration

Chasing the signaling run by tri-molecular time-lapse FRET microscopy

Kuo, H. L., Ho, P. C., Huang, S. S. & Chang, N-S., 2018 Dec 1, In : Cell Death Discovery. 4, 1, 45.

Research output: Contribution to journalArticle

Open Access
Energy Transfer
Microscopy
Signal Transduction
Proteins
Cell Death

Fast and improved bioimaging via temporal focusing multiphoton excitation microscopy with binary digital-micromirror-device holography

Sie, Y. D., Chang, C-Y., Lin, C. Y., Chang, N-S., Campagnola, P. J. & Chen, S. J., 2018 Jan 1, In : Journal of Biomedical Optics. 23, 11, 116502.

Research output: Contribution to journalArticle

Digital devices
Holography
holography
Microscopic examination
microscopy

Thesis

Investigating cancer stem cell sphere explosion via bubbling cell death

Author: 佩娟, 何., 2018 Aug 29

Supervisor: Chang, N. (Supervisor)

Student thesis: Master's Thesis

Investigating the role of Zfra and ANR40 in cancer suppression

Author: 彥瑋, 陳., 2017 Aug 29

Supervisor: Chang, N. (Supervisor)

Student thesis: Master's Thesis

Potential role of extracellular vesicles in regulating cancer cell death

Author: 湘鈴, 郭., 2017 Sep 1

Supervisor: Chang, N. (Supervisor)

Student thesis: Master's Thesis