Research Output per year
Research Output 1985 2019
- 1 - 50 out of 122 results
- Publication Year, Title (descending)
A p53/TIAF1/WWOX triad exerts cancer suppression but may cause brain protein aggregation due to p53/WWOX functional antagonism
Chou, P. Y., Lin, S. R., Lee, M. H., Schultz, L., Sze, C-I. & Chang, N-S., 2019 Jul 17, In : Cell Communication and Signaling. 17, 1, 76.Research output: Contribution to journal › Article
Editorial: WW Domain Proteins in Signaling, Cancer Growth, Neural Diseases, and Metabolic Disorders
Chang, N. S., Lin, R., Sze, C. I. & Aqeilan, R. I., 2019 Aug 2, In : Frontiers in Oncology. 9, 719.Research output: Contribution to journal › Editorial
Strategies by which WWOX-deficient metastatic cancer cells utilize to survive via dodging, compromising, and causing damage to WWOX-positive normal microenvironment
Chou, P. Y., Lai, F. J., Chen, Y. A., Sie, Y. D., Kuo, H. L., Su, W. P., Wu, C. Y., Liu, T. Y., Wen, K. Y., Hsu, L-J., Sze, C-I. & Chang, N-S., 2019 Dec 1, In : Cell Death Discovery. 5, 1, 97.Research output: Contribution to journal › Article
WW domain-containing proteins YAP and TAZ in the hippo pathway as key regulators in stemness maintenance, tissue homeostasis, and tumorigenesis
Chen, Y. A., Lu, C. Y., Cheng, T. Y., Pan, S. H., Chen, H. F. & Chang, N-S., 2019 Jan 1, In : Frontiers in Oncology. 9, FEB, 60.Research output: Contribution to journal › Review article
Chasing the signaling run by tri-molecular time-lapse FRET microscopy
Kuo, H. L., Ho, P. C., Huang, S. S. & Chang, N. S., 2018 Dec 1, In : Cell Death Discovery. 4, 1, 45.Research output: Contribution to journal › Article
Fast and improved bioimaging via temporal focusing multiphoton excitation microscopy with binary digital-micromirror-device holography
Sie, Y. D., Chang, C-Y., Lin, C. Y., Chang, N-S., Campagnola, P. J. & Chen, S. J., 2018 Jan 1, In : Journal of Biomedical Optics. 23, 11, 116502.Research output: Contribution to journal › Article
Natural zeolite for adsorbing and release of functional materials
Hovhannisyan, V. A., Dong, C. Y., Lai, F. J., Chang, N. S. & Chen, S. J., 2018 Sep 1, In : Journal of Biomedical Optics. 23, 9, 091411.Research output: Contribution to journal › Article
Phosphorylation/de-phosphorylation in specific sites of tumor suppressor WWOX and control of distinct biological events
Huang, S. S. & Chang, N-S., 2018 Jan 1, In : Experimental Biology and Medicine. 243, 2, p. 137-147 11 p.Research output: Contribution to journal › Review article
WWOX phosphorylation, signaling, and role in neurodegeneration
Liu, C. C., Ho, P. C., Lee, I. T., Chen, Y. A., Chu, C-H., Teng, C. C., Wu, S-N., Sze, C-I., Chiang, M. F. & Chang, N-S., 2018 Aug 15, In : Frontiers in Neuroscience. 12, AUG, 563.Research output: Contribution to journal › Review article
Hyaluronan activates Hyal-2/WWOX/Smad4 signaling and causes bubbling cell death when the signaling complex is overexpressed
Hsu, L. J., Hong, Q., Chen, S. T., Kuo, H. L., Schultz, L., Heath, J., Lin, S. R., Lee, M. H., Li, D. Z., Li, Z. L., Cheng, H. C., Armand, G. & Chang, N. S., 2017 Jan 1, In : Oncotarget. 8, 12, p. 19137-19155 19 p.Research output: Contribution to journal › Article
Zfra restores memory deficits in Alzheimer's disease triple-transgenic mice by blocking aggregation of TRAPPC6AΔ, SH3GLB2, tau, and amyloid β, and inflammatory NF-κB activation
Lee, M. H., Shih, Y. H., Lin, S. R., Chang, J. Y., Lin, Y. H., Sze, C-I., Kuo, Y-M. & Chang, N-S., 2017 Jun 1, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 2, p. 189-204 16 p.Research output: Contribution to journal › Article
Bubbling cell death: A hot air balloon released from the nucleus in the cold
Chang, N-S., 2016 Jun 1, In : Experimental Biology and Medicine. 241, 12, p. 1306-1315 10 p.Research output: Contribution to journal › Review article
HYAL-2-WWOX-SMAD4 signaling in cell death and anticancer response
Hsu, L-J., Chiang, M. F., Sze, C-I., Su, W. P., Yap, Y. V., Lee, I. T., Kuo, H. L. & Chang, N-S., 2016 Dec 6, In : Frontiers in Cell and Developmental Biology. 4, DEC, 141.Research output: Contribution to journal › Review article
Role of WW Domain-Containing oxidoreductase WWOX in driving T cell acute lymphoblastic leukemia maturation
Huang, S. S., Su, W. P., Lin, H. P., Kuo, H. L., Wei, H. L. & Chang, N-S., 2016 Aug 12, In : Journal of Biological Chemistry. 291, 33, p. 17319-17331 13 p.Research output: Contribution to journal › Article
Zfra induction of memory anticancer response via a novel immune cell
Su, W. P., Wang, W. J., Sze, C. I. & Chang, N. S., 2016 Sep 1, In : OncoImmunology. 5, 9, e1213935.Research output: Contribution to journal › Article
A cascade of protein aggregation bombards mitochondria for neurodegeneration and apoptosis under WWOX deficiency
Sze, C. I., Kuo, Y. M., Hsu, L. J., Fu, T. F., Chiang, M. F., Chang, J. Y. & Chang, N. S., 2015 Sep 10, In : Cell Death and Disease. 6, 9, e1881.Research output: Contribution to journal › Comment/debate
Expression of WW domain–Containing oxidoreductase WWOX in pterygium
Huang, Y-H., Chang, N-S. & Tseng, S. H., 2015 Jun 25, In : Molecular Vision. 21, p. 711-717 7 p.Research output: Contribution to journal › Article
Fabrication of three-dimensional multi-protein microstructures for cell migration and adhesion enhancement
Da Sie, Y., Li, Y. C., Chang, N. S., Campagnola, P. J. & Chen, S. J., 2015 Jan 1, In : Biomedical Optics Express. 6, 2, p. 480-490 11 p.Research output: Contribution to journal › Article
Introduction to a Thematic Issue for WWOX
Chang, N-S., 2015 Mar 25, In : Experimental Biology and Medicine. 240, 3, p. 281-284 4 p.Research output: Contribution to journal › Article
Strategies of oncogenic microbes to deal with WW domain-containing oxidoreductase
Chang, Y., Lan, Y. Y., Hsiao, J-R. & Chang, N-S., 2015 Mar 25, In : Experimental Biology and Medicine. 240, 3, p. 329-337 9 p.Research output: Contribution to journal › Article
Trafficking protein particle complex 6A delta (TRAPPC6AΔ) is an extracellular plaque-forming protein in the brain
Chang, J. Y., Lee, M. H., Lin, S. R., Yang, L. Y., Sun, H-F., Sze, C-I., Hong, Q., Lin, Y-S., Chou, Y. T., Hsu, L-J., Jan, M. S., Gong, C. X. & Chang, N-S., 2015 Jan 1, In : Oncotarget. 6, 6, p. 3578-3589 12 p.Research output: Contribution to journal › Article
UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperatures
Chen, S. J., Lin, P. W., Lin, H. P., Huang, S. S., Lai, F. J., Sheu, H. M., Hsu, L. J. & Chang, N. S., 2015 Jan 1, In : Oncotarget. 6, 10, p. 8007-8018 12 p.Research output: Contribution to journal › Article
WWOX suppresses prostate cancer cell progression through cyclin D1-mediated cell cycle arrest in the G1 phase
Lin, J. T., Li, H. Y., Chang, N-S., Lin, C. H., Chen, Y. C. & Lu, P-J., 2015 Feb 1, In : Cell Cycle. 14, 3, p. 408-416 9 p.Research output: Contribution to journal › Article
Zfra activates memory Hyal-2+ CD3- CD19- spleen cells to block cancer growth, stemness, and metastasis in vivo
Lee, M. H., Su, W. P., Wang, W. J., Lin, S. R., Lu, C. Y., Chen, Y. A., Chang, J. Y., Huang, S. S., Chou, P. Y., Ye, S. R., Chen, S. J., He, H., Liu, T. H., Chou, Y. T., Hsu, L. J., Lai, F. J., Chen, S. J., Lee, H. C., Kakhniashvili, D., Goodman, S. R. & 1 others, , 2015 Jan 1, In : Oncotarget. 6, 6, p. 3737-3751 15 p.Research output: Contribution to journal › Article
Folate deficiency-induced oxidative stress contributes to neuropathy in young and aged zebrafish - Implication in neural tube defects and Alzheimer's diseases
Kao, T. T., Chu, C. Y., Lee, G. H., Hsiao, T. H., Cheng, N. W., Chang, N. S., Chen, B. H. & Fu, T. F., 2014 Jan 1, In : Neurobiology of Disease. 71, 1, p. 234-244 11 p.Research output: Contribution to journal › Article
MODIFIED HYALURONAN AND USES THEREOF IN CANCER TREATMENT
Chang, N-S., 2014 Sep 18, Patent No. 9375447Research output: Patent
Visualization of subunit interactions and ternary complexes of protein phosphatase 2A in mammalian cells
Shu-Ting, M., Shang-Ju, C., Tai-Yu, L., Yu-Ling, C., Cheng-En, C., Spencer, C. H. K., Kelie, M. R., Yung-Cheng, C., Chang, N-S., Brian, E. W. & Chiang, C-W., 2014 Dec 23, In : PLoS ONE. 9, 12Research output: Contribution to journal › Article
WW domain-containing oxidoreductase in neuronal injury and neurological diseases
Chang, H. T., Liu, C. C., Chen, S. T., Yap, Y. V., Chang, N-S. & Sze, C-I., 2014 Jan 1, In : Oncotarget. 5, 23, p. 11792-11799 8 p.Research output: Contribution to journal › Article
WWOX suppresses KLF5 expression and breast cancer cell growth
Ge, F., Chen, W., Yang, R., Zhou, Z., Chang, N-S., Chen, C., Zou, T., Liu, R., Tan, J. & Ren, G., 2014 Jan 1, In : Chinese Journal of Cancer Research. 26, 5, p. 511-516 6 p.Research output: Contribution to journal › Article
Assessing current therapeutic approaches to decode potential resistance mechanisms in glioblastomas
Sze, C-I., Su, W. P., Chiang, M. F., Lu, C. Y., Chen, Y. A. & Chang, N-S., 2013 Dec 24, In : Frontiers in Oncology. 3 MAR, Article 00059.Research output: Contribution to journal › Short survey
Expression of WW domain-containing oxidoreductase WOX1 in human nervous system tumors
Chiang, M. F., Chen, S. T., Lo, C. P., Sze, C-I., Chang, N-S. & Chen, Y. J., 2013 Jan 1, In : Analytical Cellular Pathology. 36, 5-6, p. 133-147 15 p.Research output: Contribution to journal › Article
High-throughput fabrication of gray-level biomicrostructures via temporal focusing excitation and laser pulse control
Li, Y. C., Cheng, L. C., Chang, C-Y., Lin, C. Y., Chang, N-S., Campagnola, P. J., Dong, C. Y. & Chen, S. J., 2013 Jul 1, In : Journal of Biomedical Optics. 18, 7, 075004.Research output: Contribution to journal › Article
Tumor suppressor WWOX and p53 alterations and drug resistance in glioblastomas
Chiang, M. F., Chou, P. Y., Wang, W. J., Sze, C-I. & Chang, N-S., 2013 Dec 24, In : Frontiers in Oncology. 3 MAR, Article 00043.Research output: Contribution to journal › Article
WW domain-containing oxidoreductase is involved in upregulation of matrix metalloproteinase 9 by Epstein-Barr virus latent membrane protein 2A
Lan, Y. Y., Wu, S. Y., Lai, H. C., Chang, N-S., Chang, F. H., Tsai, M. H., Su, I. J. & Chang, Y., 2013 Jul 12, In : Biochemical and Biophysical Research Communications. 436, 4, p. 672-676 5 p.Research output: Contribution to journal › Article
WWOX suppresses autophagy for inducing apoptosis in methotrexate-treated human squamous cell carcinoma
Tsai, C. W., Lai, F. J., Sheu, H. M., Lin, Y. S., Chang, T. H., Jan, M. S., Chen, S. M., Hsu, P. C., Huang, T. T., Huang, T. C., Sheen, M. C., Chen, S. T., Chang, W. C., Chang, N. S. & Hsu, L. J., 2013 Sep 1, In : Cell Death and Disease. 4, 9, e792.Research output: Contribution to journal › Article
Investigation of two-photon excited fluorescence increment via crosslinked bovine serum albumin
Lin, C. Y., Lien, C. H., Cho, K. C., Chang, C-Y., Chang, N-S., Campagnola, P. J., Dong, C. Y. & Chen, S. J., 2012 Jun 18, In : Optics Express. 20, 13, p. 13669-13676 8 p.Research output: Contribution to journal › Article
Overexpression of WW domain-containing oxidoreductase WOX1 preferentially induces apoptosis in human glioblastoma cells harboring mutant p53
Chiang, M. F., Yeh, S. T., Liao, H. F., Chang, N-S. & Chen, Y. J., 2012 Sep 1, In : Biomedicine and Pharmacotherapy. 66, 6, p. 433-438 6 p.Research output: Contribution to journal › Article
Prc contributes to Escherichia coli evasion of classical complement-mediated serum killing
Wang, C. Y., Wang, S. W., Huang, W. C., Kim, K. S., Chang, N. S., Wang, Y. H., Wu, M. H. & Teng, C. H., 2012 Oct 1, In : Infection and Immunity. 80, 10, p. 3399-3409 11 p.Research output: Contribution to journal › Article
Spatiotemporal focusing-based widefield multiphoton microscopy for fast optical sectioning
Cheng, L. C., Chang, C-Y., Lin, C. Y., Cho, K. C., Yen, W. C., Chang, N-S., Xu, C., Dong, C. Y. & Chen, S. J., 2012 Apr 9, In : Optics Express. 20, 8, p. 8939-8948 10 p.Research output: Contribution to journal › Article
TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death
Chang, J. Y., Chiang, M. F., Lin, S. R., Lee, M. H., He, H., Chou, P. Y., Chen, S. J., Chen, Y. A., Yang, L. Y., Lai, F. J., Hsieh, C. C., Hsieh, T. H., Sheu, H. M., Sze, C-I. & Chang, N-S., 2012 Apr 1, In : Cell Death and Disease. 3, 4, e302.Research output: Contribution to journal › Article
WW Domain-containing oxidoreductase is a potential receptor for sex steroid hormones
Chang, N-S., 2012, Unknown Publisher.Research output: Book/Report › Book
WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3Β
Wang, H. Y., Juo, L. I., Lin, Y. T., Hsiao, M., Lin, J. T., Tsai, C. H., Tzeng, Y. H., Chuang, Y. C., Chang, N-S., Yang, C. N. & Lu, P-J., 2012 Jun 1, In : Cell Death and Differentiation. 19, 6, p. 1049-1059 11 p.Research output: Contribution to journal › Article
Identification of an in vivo MEK/WOX1 complex as a master switch for apoptosis in t cell leukemia
Lin, H. P., Chang, J. Y., Lin, S. R., Lee, M. H., Huang, S. S., Hsu, L-J. & Chang, N-S., 2011 May 1, In : Genes and Cancer. 2, 5, p. 550-562 13 p.Research output: Contribution to journal › Article
Solanum incanum extract (SR-T100) induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway
Wu, C. H., Liang, C. H., Shiu, L. Y., Chang, L. C., Lin, T. S., Lan, C. C. E., Tsai, J-C., Wong, T-W., Wei, K. J., Lin, T. K., Chang, N-S. & Sheu, H. M., 2011 Aug 1, In : Journal of Dermatological Science. 63, 2, p. 83-92 10 p.Research output: Contribution to journal › Article
Imaging live cell membranes via surface plasmon-enhanced fluorescence and phase microscopy
He, R. Y., Lin, C. Y., Su, Y. D., Chiu, K. C., Chang, N-S., Wu, H-L. & Chen, S. J., 2010 Feb 15, In : Optics Express. 18, 4, p. 3649-3659 11 p.Research output: Contribution to journal › Article
Signaling from membrane receptors to tumor suppressor WW domain-containing oxidoreductase
Chang, J. Y., He, R. Y., Lin, H. P., Hsu, L-J., Lai, F. J., Hong, Q., Chen, S. J. & Chang, N-S., 2010 Jul 1, In : Experimental Biology and Medicine. 235, 7, p. 796-804 9 p.Research output: Contribution to journal › Short survey
Study of cell-biosubstrate contacts via surface plasmon polariton phase microscopy
Su, Y. D., Chiu, K. C., Chang, N-S., Wu, H-L. & Chen, S. J., 2010 Sep 13, In : Optics Express. 18, 19, p. 20125-20135 11 p.Research output: Contribution to journal › Article
TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease
Lee, M. H., Lin, S. R., Chang, J. Y., Schultz, L., Heath, J., Hsu, L. J., Kuo, Y. M., Hong, Q., Chiang, M. F., Gong, C. X., Sze, C. I. & Chang, N. S., 2010 Dec 1, In : Cell Death and Disease. 1, 12, e110.Research output: Contribution to journal › Article
Zfra is a small wizard in the mitochondrial apoptosis
Dudekula, S., Lee, M. H., Hsu, L-J., Chen, S. J. & Chang, N-S., 2010 Jan 1, In : Aging. 2, 12, p. 1023-1029 7 p.Research output: Contribution to journal › Article
Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells
Hong, Q., Sze, C-I., Lin, S. R., Lee, M. H., He, R. Y., Schultz, L., Chang, J. Y., Chen, S. J., Boackle, R. J., Hsu, L-J. & Chang, N-S., 2009 Jun 1, In : PloS one. 4, 6, e5755.Research output: Contribution to journal › Article