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Pai-Sheng Chen

Assistant Professor

  • 1301 Citations
  • 16 h-Index
20052019

Research output per year

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Personal profile

Education

  • Ph.D., National Taiwan University

Research Interests

  • Tumor Biology
  • microRNA
  • Molecular cancer therapeutics

Experience

  • 2012/07~present Assistant Professor, Department of Medical Laboratory Science and Biotechnology, National Cheng-Kung University
  • 2010/08 - 2012/07Postdoctoral Fellow, Department of Oncology, College of Medicine, National Taiwan University
  • 2009/02 - 2010/07 Postdoctoral Fellow, Genomic Research Center, College of Medicine, National Taiwan University

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Projects

研究 Dicer 蛋白失調在大腸直腸癌進展中的角色: 從功能及調控的探討到可能的治療契機-探討大腸癌中Dicer泛素化依賴之細胞自噬降解途徑之功能性機制(2/3)

Chen, P.

17-08-01 → 18-07-31

Project: Research project

解開HIF-1 alpha調控DGCR8-Exo10RRP6複合體進而促進乳癌腫瘤生成之機制

Chen, P.

17-08-01 → 18-07-31

Project: Research project

研究 Dicer 蛋白失調在大腸直腸癌進展中的角色: 從功能及調控的探討到可能的治療契機-探討大腸癌中Dicer泛素化依賴之細胞自噬降解途徑之功能性機制(1/3)

Chen, P.

16-08-01 → 17-07-31

Project: Research project

缺氧誘發因子1alpha抑制Dicer表現以及miRNA生合成之機制探討

Chen, P.

16-08-01 → 17-07-31

Project: Research project

缺氧誘發因子1alpha抑制Dicer表現以及miRNA生合成之機制探討

Chen, P.

15-08-01 → 16-07-31

Project: Research project

Research Output

BIRC5/Survivin is a novel ATG12–ATG5 conjugate interactor and an autophagy-induced DNA damage suppressor in human cancer and mouse embryonic fibroblast cells

Lin, T. Y., Chan, H. H., Chen, S. H., Sarvagalla, S., Chen, P. S., Coumar, M. S., Cheng, S. M., Chang, Y. C., Lin, C. H., Leung, E. & Cheung, C. H. A., 2019 Jan 1, (Accepted/In press) In : Autophagy.

Research output: Contribution to journal › Review article

Open Access
    • 3 Citations (Scopus)

    Mutation of the PTCH1 gene predicts recurrence of breast cancer

    Wang, C. Y., Chang, Y. C., Kuo, Y. L., Lee, K. T., Chen, P. S., Cheung, C. H. A., Chang, C. P., Phan, N. N., Shen, M. R. & Hsu, H. P., 2019 Nov 8, In : Scientific reports. 9, 1, 1 p., 16359.

    Research output: Contribution to journal › Article

    Open Access

    • TARBP2-enhanced resistance during tamoxifen treatment in breast cancer

    Wang, M. Y., Huang, H. Y., Kuo, Y. L., Lo, C., Sun, H. Y., Lyu, Y. J., Chen, B. R., Li, J. N. & Chen, P. S., 2019 Feb, In : Cancers. 11, 2, 210.

    Research output: Contribution to journal › Article

    Open Access
    • 2 Citations (Scopus)

    TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma

    Lai, H. H., Li, C. W., Hong, C. C., Sun, H. Y., Chiu, C. F., Ou, D. L. & Chen, P. S., 2019 Apr, In : Molecular Oncology. 13, 4, p. 928-945 18 p.

    Research output: Contribution to journal › Article

    Open Access
    • 3 Citations (Scopus)

    TARBP2-mediated destabilization of Nanog overcomes sorafenib resistance in hepatocellular carcinoma

    Lai, H., Li, C., Hong, C., Sun, H., Chiu, C., Ou, D. & Chen, P-S., 2019 Jan 18, In : Molecular Oncology.

    Research output: Contribution to journal › Article