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Po-Hsien Huang

Associate Professor

 https://orcid.org/0000-0002-2997-5181
  • 851 Citations
  • 11 h-Index
20092019
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Personal profile

Education

  • 美國俄亥俄州立大學藥學系博士

Research Interests

  • 表觀基因及表觀遺傳調控
  • 腫瘤標誌物

Experience

  • 2018/07 ~ 迄今 國立成功大學生物化學科暨生物化學暨分子生物學研究所 副教授

Fingerprint Dive into the research topics where Po-Hsien Huang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Histone Deacetylase Inhibitors Medicine & Life Sciences
Epigenomics Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Prostatic Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Histones Medicine & Life Sciences
Methylation Medicine & Life Sciences
Succinic Acid Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2018

藉由生物力學的研究探討與纖維化相關疾病之病理機制-探討基質硬度對胰臟星狀細胞活化及胰臟癌發展的影響(2/3)

Huang, P.

17-08-01 → 18-07-31

Project: Research project

探討整合素跨膜受體蛋白於KRAS基因去依存性胰臟癌之治療標靶特性

Huang, P.

17-08-01 → 18-07-31

Project: Research project

探討整合素跨膜受體蛋白於KRAS基因去依存性胰臟癌之治療標靶特性

Huang, P.

16-08-01 → 17-07-31

Project: Research project

藉由生物力學的研究探討與纖維化相關疾病之病理機制-探討基質硬度對胰臟星狀細胞活化及胰臟癌發展的影響(1/3)

Huang, P.

16-08-01 → 17-07-31

Project: Research project

VAV1所調控之目標基因於胰臟癌中的功能與角色之探討

Huang, P.

15-08-01 → 16-07-31

Project: Research project

Research Output 2009 2019

  • 851 Citations
  • 11 h-Index
  • 15 Article
  • 2 Review article

Pancreatic stellate cells activated by mutant KRAS-mediated PAI-1 upregulation foster pancreatic cancer progression via IL-8

Wang, H. C., Lin, Y. L., Hsu, C. C., Chao, Y. J., Hou, Y. C., Chiu, T. J., Huang, P. H., Tang, M. J., Chen, L. T. & Shan, Y. S., 2019 Jan 1, In : Theranostics. 9, 24, p. 7168-7183 16 p.

Research output: Contribution to journal › Article

Open Access
Pancreatic Stellate Cells
Plasminogen Activator Inhibitor 1
Interleukin-8
Pancreatic Neoplasms
Up-Regulation
5 Citations (Scopus)

Pharmacological strategies to target oncogenic KRAS signaling in pancreatic cancer

Chuang, H. C., Huang, P-H., Kulp, S. K. & Chen, C. S., 2017 Mar 1, In : Pharmacological Research. 117, p. 370-376 7 p.

Research output: Contribution to journal › Review article

Pancreatic Neoplasms
Pharmacology
Nucleotide Motifs
History
Ligands
4 Citations (Scopus)

TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1

Huang, P. H., Lu, P. J., Ding, L. Y., Chu, P. C., Hsu, W. Y., Chen, C. S., Tsao, C. C., Chen, B. H., Lee, C. T., Shan, Y. S. & Chen, C. S., 2017 Apr 20, In : Oncogene. 36, 16, p. 2202-2214 13 p.

Research output: Contribution to journal › Article

Pancreatic Neoplasms
Epigenomics
Phenotype
Epithelial-Mesenchymal Transition
gemcitabine
7 Citations (Scopus)

Suppression of Tumor Growth and Muscle Wasting in a Transgenic Mouse Model of Pancreatic Cancer by the Novel Histone Deacetylase Inhibitor AR-42

Henderson, S. E., Ding, L. Y., Mo, X., Bekaii-Saab, T., Kulp, S. K., Chen, C. S. & Huang, P-H., 2016 Jan 1, In : Neoplasia (United States). 18, 12, p. 765-774 10 p.

Research output: Contribution to journal › Article

Histone Deacetylase Inhibitors
Pancreatic Neoplasms
Transgenic Mice
Muscles
Histone Deacetylases
11 Citations (Scopus)

Histone deacetylase inhibitor AR42 regulates telomerase activity in human glioma cells via an Akt-dependent mechanism

Yang, Y. L., Huang, P. H., Chiu, H. C., Kulp, S. K., Chen, C. S., Kuo, C. J., Chen, H. D. & Chen, C. S., 2013 May 24, In : Biochemical and Biophysical Research Communications. 435, 1, p. 107-112 6 p.

Research output: Contribution to journal › Article

Histone Deacetylase Inhibitors
Telomerase
Human Activities
Glioma
Histone Deacetylases