• 259 Citations
  • 9 h-Index
20082020
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Research Output 2008 2020

  • 259 Citations
  • 9 h-Index
  • 21 Article
  • 1 Letter
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Article
2020

A selective Aurora-A 5′-UTR siRNA inhibits tumor growth and metastasis

Lai, C. H., Chen, R. Y., Hsieh, H. P., Tsai, S. J., Chang, K. C., Yen, C. J., Huang, Y. C., Liu, Y. W., Lee, J. C., Lai, Y. C., Hung, L. Y. & Lin, B. W., 2020 Mar 1, In : Cancer Letters. 472, p. 97-107 11 p.

Research output: Contribution to journalArticle

5' Untranslated Regions
Small Interfering RNA
Neoplasm Metastasis
Growth
Neoplasms
2019
Open Access
Colorectal Neoplasms
oxaliplatin
human ERBB2 protein
Fluorescence In Situ Hybridization
Therapeutics
3 Citations (Scopus)

MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway

Chu, C. A., Lee, C. T., Lee, J. C., Wang, Y. W., Huang, C. T., Lan, S. H., Lin, P. C., Lin, B. W., Tian, Y. F., Liu, H. S. & Chow, N. H., 2019 May, In : EBioMedicine. 43, p. 270-281 12 p.

Research output: Contribution to journalArticle

Open Access
Class III Phosphatidylinositol 3-Kinases
Autophagy
Tumors
Colorectal Neoplasms
Genes
2018
1 Citation (Scopus)

The EGF/hnRNP Q1 axis is involved in tumorigenesis via the regulation of cell cycle-related genes

Wang, Y. C., Chang, K-C., Lin, P-W., Lee, J-C., Lai, C. H., Lin, L. J., Yen, Y., Lin, C. S., Yang, S. J., Lin, P-C., Lee, C-T. & Hung, L-Y., 2018 Jun 1, In : Experimental and Molecular Medicine. 50, 6, 70.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
cdc Genes
Epidermal Growth Factor
Carcinogenesis
Genes
2017
23 Citations (Scopus)

Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness

Hou, P. C., Li, Y. H., Lin, S. C., Lin, S. C., Lee, J. C., Lin, B. W., Liou, J. P., Chang, J. Y., Kuo, C. C., Liu, Y. M., Sun, H. S. & Tsai, S. J., 2017 Aug 15, In : Cancer Research. 77, 16, p. 4305-4316 12 p.

Research output: Contribution to journalArticle

Dual-Specificity Phosphatases
Dual Specificity Phosphatase 2
Colonic Neoplasms
Down-Regulation
Neoplasms
6 Citations (Scopus)
Mucinous Adenocarcinoma
Adenocarcinoma
CpG Islands
Survival
Phenotype
7 Citations (Scopus)

Translational upregulation of Aurora-A by hnRNP Q1 contributes to cell proliferation and tumorigenesis in colorectal cancer

Lai, C. H., Huang, Y. C., Lee, J. C., Tseng, J. T. C., Chang, K. C., Chen, Y. J., Ding, N. J., Huang, P. H., Chang, W. C., Lin, B. W., Chen, R. Y., Wang, Y. C., Lai, Y. C. & Hung, L. Y., 2017 Jan 1, In : Cell Death and Disease. 8, 1, e2555.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoproteins
Colorectal Neoplasms
Carcinogenesis
Up-Regulation
Cell Proliferation
2016
3 Citations (Scopus)

Epigenetic silencing of miR-137 contributes to early colorectal carcinogenesis by impaired Aurora-A inhibition

Huang, Y. C., Lee, C. T., Lee, J. C., Liu, Y. W., Chen, Y. J., Tseng, J. T., Kang, J. W., Sheu, B. S., Lin, B. W. & Hung, L. Y., 2016 Jan 1, In : Oncotarget. 7, 47, p. 76852-76866 15 p.

Research output: Contribution to journalArticle

Polyps
Epigenomics
Carcinogenesis
Colorectal Neoplasms
Colonic Neoplasms
17 Citations (Scopus)

Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer

Chien, C. W., Hou, P. C., Wu, H. C., Chang, Y. L., Lin, S. C., Lin, S. C., Lin, B. W., Lee, J. C., Chang, Y. J., Sun, H. S. & Tsai, S. J., 2016 Nov 10, In : Oncogene. 35, 45, p. 5872-5881 10 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Colonic Neoplasms
Pharmaceutical Preparations
Oncogenes
Antibodies
2015
4 Citations (Scopus)

Health-related quality of life and cost comparison of adjuvant capecitabine versus 5-fluorouracil/leucovorin in stage III colorectal cancer patients

Chen, H. H., Chen, W. T. L., Lee, H. C., Lin, J. K., Fang, C. Y., Chou, Y. H., Lin, P. C., Lin, B. W., Huang, C. C., Yeh, C. H., Hsu, H. H., Chen, H. C., Ting, W. C., Yang, M. C. & Tan, E. C. H., 2015 Jan 1, In : Quality of Life Research. 24, 2, p. 473-484 12 p.

Research output: Contribution to journalArticle

Leucovorin
Fluorouracil
Colorectal Neoplasms
Quality of Life
Costs and Cost Analysis
2014
9 Citations (Scopus)

Overexpression of Aurora-C interferes with the spindle checkpoint by promoting the degradation of Aurora-B

Lin, B. W., Wang, Y. C., Chang-Liao, P. Y., Lin, Y. J., Yang, S. T., Tsou, J. H., Chang, K. C., Liu, Y. W., Tseng, J. T., Lee, C. T., Lee, J. C. & Hung, L. Y., 2014 Mar, In : Cell Death and Disease. 5, 3, e1106.

Research output: Contribution to journalArticle

M Phase Cell Cycle Checkpoints
Aurora Kinase B
Nocodazole
Neoplasms
Chromosome Segregation
11 Citations (Scopus)

STK31 Is a Cell-Cycle Regulated Protein That Contributes to the Tumorigenicity of Epithelial Cancer Cells

Kuo, P-L., Huang, Y. L., Hsieh, C. C. J., Lee, J-C., Lin, P-W. & Hung, L-Y., 2014 Mar 25, In : PloS one. 9, 3, e93303.

Research output: Contribution to journalArticle

Cell Cycle Proteins
Protein-Serine-Threonine Kinases
cell cycle
epithelial cells
Epithelial Cells
2013
5 Citations (Scopus)
Rectal Neoplasms
Neoplasms
Surgeons
Lymph Nodes
Anus Neoplasms
2011
21 Citations (Scopus)

Aberrantly expressed AURKC enhances the transformation and tumourigenicity of epithelial cells

Tsou, J. H., Chang, K-C., Chang-Liao, P. Y., Yang, S. T., Lee, C-T., Chen, Y-P., Lee, Y. C., Lin, P-W., Lee, J-C., Shen, M-R., Chuang, C. K., Chang, W. C., Wang, J-M. & Hung, L-Y., 2011 Oct 1, In : Journal of Pathology. 225, 2, p. 243-254 12 p.

Research output: Contribution to journalArticle

Epithelial Cells
Neoplasms
Colorectal Neoplasms
Thyroid Neoplasms
Uterine Cervical Neoplasms
9 Citations (Scopus)
Pulmonary Infarction
Taiwan
Systemic Lupus Erythematosus
Retrospective Studies
Antiphospholipid Syndrome
66 Citations (Scopus)

Overexpression of pyruvate dehydrogenase kinase 3 increases drug resistance and early recurrence in colon cancer

Lu, C. W., Lin, S-C., Chien, C. W., Lin, S-C., Lee, C-T., Lin, P-W., Lee, J-C. & Tsai, S-J., 2011 Sep 1, In : American Journal of Pathology. 179, 3, p. 1405-1414 10 p.

Research output: Contribution to journalArticle

Drug Resistance
Colonic Neoplasms
Recurrence
Neoplasms
Hypoxia-Inducible Factor 1
2010
12 Citations (Scopus)

Secondary Aortocolic Fistula: Case Report and Review of the Literature

Luo, C-Y., Lai, C-H., Wen, J-S. & Lin, P-W., 2010 Jan 1, In : Annals of Vascular Surgery. 24, 2, p. 256.e5-256.e12

Research output: Contribution to journalArticle

Fistula
Prostheses and Implants
Iliac Artery
Transplants
Laparotomy
14 Citations (Scopus)

Translational up-regulation of Aurora-A in EGFR-overexpressed cancer

Lai, C. H., Tseng, J. T., Lee, Y. C., Chen, Y. J., Lee, J. C., Lin, B. W., Huang, T. C., Liu, Y. W., Leu, T. H., Liu, Y. W., Chen, Y. P., Chang, W. C. & Hung, L. Y., 2010 Jun 1, In : Journal of Cellular and Molecular Medicine. 14, 6 B, p. 1520-1531 12 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Up-Regulation
Epidermal Growth Factor
Neoplasms
Exons
2009
Ileal Diseases
X Ray Computed Tomography
Behcet Syndrome
Ileum
Abdominal Pain
2008
45 Citations (Scopus)

Regulation of CD151 by hypoxia controls cell adhesion and metastasis in colorectal cancer

Chien, C. W., Lin, S. C., Lai, Y. Y., Lin, B. W., Lin, S. C., Lee, J. C. & Tsai, S. J., 2008 Dec 15, In : Clinical Cancer Research. 14, 24, p. 8043-8051 9 p.

Research output: Contribution to journalArticle

Cell Adhesion
Colorectal Neoplasms
Neoplasm Metastasis
Neoplasms
Hypoxia-Inducible Factor 1