• 3749 Citations
  • 31 h-Index
1989 …2019
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Research Output 1989 2019

  • 3749 Citations
  • 31 h-Index
  • 212 Article
  • 5 Letter
  • 3 Review article
  • 1 Conference article
2019
1 Citation (Scopus)
Bisoprolol
neurons
Neurons
Depolarization
Clamping devices
1 Citation (Scopus)
Open Access
Photosensitizing Agents
Membranes
Lighting
verteporfin
Dithiothreitol
5 Citations (Scopus)
ivabradine
Neurons
linopirdine
Endocrine Cells
Reducing Agents
Kaurane Diterpenes
Croton
Diterpenes
Euphorbiaceae
Euphorbia
Nalbuphine
Narcotic Antagonists
Opioid Receptors
Inhibitory Concentration 50
Neurons
Open Access
Ganoderma
spores
Spores
Cations
Chemical activation
3 Citations (Scopus)

Evidence for effective multiple K+current inhibitions by Tolvaptan, a non-peptide antagonist of vasopressin V2 receptor

Lu, T. L., Chang, W. T., Chan, C. H. & Wu, S. N., 2019 Jan 1, In : Frontiers in Pharmacology. 10, FEB, 76.

Research output: Contribution to journalArticle

Open Access
Vasopressin Receptors
flupirtine
Inappropriate ADH Syndrome
Calcium-Activated Potassium Channels
Neuroendocrine Cells
Open Access
Prolyl-Hydroxylase Inhibitors
hypoxia
inhibitors
Depolarization
Prolyl Hydroxylases

High effectiveness in actions of carfilzomib on delayed-rectifier K+ current and on spontaneous action potentials

So, E. C., Liu, P. Y., Lee, C. C. & Wu, S. N., 2019 Jan 1, In : Frontiers in Pharmacology. 10, 1163.

Research output: Contribution to journalArticle

Open Access
Action Potentials
Vascular Smooth Muscle
Smooth Muscle Myocytes
Neuroendocrine Cells
Proteasome Inhibitors

MST3 is involved in ENaC-mediated hypertension

Lu, T. J., Kan, W. C., Yang, S. S., Jiang, S. T., Wu, S. N., Ling, P., Bao, B. Y., Lin, C. Y., Yang, Z. Y., Weng, Y. P., Chan, C. H. & Lu, T. L., 2019 Jan 1, In : American Journal of Physiology - Renal Physiology. 317, 7, p. F30-F42

Research output: Contribution to journalArticle

Epithelial Sodium Channels
Phosphotransferases
Hypertension
Hypernatremia
Hypokalemia
5 Citations (Scopus)
Cyclooxygenase 2
Analgesics
Ions
parecoxib
Cyclooxygenase 2 Inhibitors
2 Citations (Scopus)

The biochemical and electrophysiological profiles of amniotic fluid-derived stem cells following Wnt signaling modulation cardiac differentiation

Liu, Y. W., Fang, Y. H., Su, C. T., Hwang, S. M., Liu, P. Y. & Wu, S. N., 2019 Dec 1, In : Cell Death Discovery. 5, 1, 59.

Research output: Contribution to journalArticle

Open Access
Amniotic Fluid
Stem Cells
Cardiac Myocytes
Action Potentials
Myosin Light Chains
Open Access
AMPA Receptors
Potassium
Sodium
Electric potential
Neurons
2 Citations (Scopus)

The Protective Role of Peroxisome Proliferator-Activated Receptor-Gamma in Seizure and Neuronal Excitotoxicity

Hung, T. Y., Chu, F. L., Wu, D. C., Wu, S. N. & Huang, C. W., 2019 Aug 15, In : Molecular Neurobiology. 56, 8, p. 5497-5506 10 p.

Research output: Contribution to journalArticle

pioglitazone
Peroxisome Proliferator-Activated Receptors
PPAR gamma
Seizures
Pilocarpine
2018
2 Citations (Scopus)
Angiotensin II Type 1 Receptor Blockers
Cardiac Myocytes
Potassium
Sodium
Action Potentials
6 Citations (Scopus)

Defective trafficking of Kv2.1 channels in MPTP-induced nigrostriatal degeneration

Chao, R. Y., Cheng, C. H., Wu, S-N. & Chen, P., 2018 Feb 1, In : Journal of Neurochemistry. 144, 4, p. 483-497 15 p.

Research output: Contribution to journalArticle

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Parkinson Disease
Dopaminergic Neurons
Protein Transport
Neurons
2 Citations (Scopus)
Chemical activation
Cells
Cell Line
Neuroendocrine Cells
Monoterpenes
4 Citations (Scopus)

Huntington mice demonstrate diminished pain response in inflammatory pain model

Lin, Y. C., Hsiao, H. T., Wu, S-N. & Liu, Y-C., 2018 Jan 1, In : Anesthesia and analgesia. 126, 2, p. 661-669 9 p.

Research output: Contribution to journalArticle

Huntington Disease
Pain
Spinal Cord
Spinal Ganglia
Cytokines
4 Citations (Scopus)
Miniature Postsynaptic Potentials
Rotenone
Electron Transport
Neurons
Niflumic Acid
4 Citations (Scopus)
Acid Sensing Ion Channels
Olfactory Receptor Neurons
Neurons
Chemical activation
Ion Channels
7 Citations (Scopus)

Pioglitazone, a PPAR-γ activator, stimulates BK Ca but suppresses IK M in hippocampal neurons

Chen, T. S., Lai, M. C., Hung, T. Y., Lin, K. M., Huang, C. W. & Wu, S. N., 2018 Aug 29, In : Frontiers in Pharmacology. 9, AUG, 977.

Research output: Contribution to journalArticle

pioglitazone
Peroxisome Proliferator-Activated Receptors
Neurons
Large-Conductance Calcium-Activated Potassium Channels
Apamin
3 Citations (Scopus)

Sodium Metabisulfite: Effects on Ionic Currents and Excitotoxicity

Lai, M. C., Hung, T. Y., Lin, K. M., Sung, P-S., Wu, S. J., Yang, C. S., Wu, Y-J., Tsai, J. J., Wu, S-N. & Huang, C-W., 2018 Jul 1, In : Neurotoxicity Research. 34, 1

Research output: Contribution to journalArticle

Sodium Channels
Pilocarpine
Clamping devices
Neurons
Rats

Stimulatory action of telmisartan, an antagonist of angiotensin II receptor, on voltage-gated Na + current: Experimental and theoretical studies

Chang, T. T., Yang, C. J., Lee, Y. C. & Wu, S-N., 2018 Jan 1, In : Chinese Journal of Physiology. 61, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Angiotensin Receptor Antagonists
Theoretical Models
Neurons
Neuroendocrine Cells
Peroxisome Proliferator-Activated Receptors
5 Citations (Scopus)

The comprehensive electrophysiological study of curcuminoids on delayed-rectifier K+ currents in insulin-secreting cells

Kuo, P-C., Yang, C. J., Lee, Y. C., Chen, P., Liu, Y-C. & Wu, S-N., 2018 Jan 15, In : European Journal of Pharmacology. 819, p. 233-241 9 p.

Research output: Contribution to journalArticle

Curcumin
Insulin-Secreting Cells
Insulin
Membrane Potentials
Nicorandil

The Novel Effect of Immunomodulator-Glatiramer Acetate on Epileptogenesis and Epileptic Seizures

Lai, M. C., Lin, K. M., Yeh, P. S., Wu, S-N. & Huang, C-W., 2018 Oct 1, In : Cellular Physiology and Biochemistry. 50, 1, p. 169-178 10 p.

Research output: Contribution to journalArticle

Immunologic Factors
Epilepsy
Seizures
Interleukin-1
Pilocarpine
6 Citations (Scopus)

WWOX phosphorylation, signaling, and role in neurodegeneration

Liu, C. C., Ho, P. C., Lee, I. T., Chen, Y. A., Chu, C. H., Teng, C. C., Wu, S. N., Sze, C. I., Chiang, M. F. & Chang, N. S., 2018 Aug 15, In : Frontiers in Neuroscience. 12, AUG, 563.

Research output: Contribution to journalReview article

Amyloid
Phosphorylation
Genetic Suppression
Glycogen Synthase Kinase 3
Proteins
2017
3 Citations (Scopus)

Important modifications by sugammadex, a modified γ-cyclodextrin, of ion currents in differentiated NSC-34 neuronal cells

Hsu, H. T., Lo, Y. C., Huang, Y. M., Tseng, Y. T. & Wu, S. N., 2017 Jan 3, In : BMC Neuroscience. 18, 1, 6.

Research output: Contribution to journalArticle

Cyclodextrins
Ions
Sugammadex
Neuromuscular Blocking Agents
Membranes
13 Citations (Scopus)

Stimulatory actions of a novel thiourea derivative on large-conductance, calcium-activated potassium channels

Wu, S-N., Chern, J. H., Shen, S., Chen, H. H., Hsu, Y. T., Lee, C. C., Chan, M. H., Lai, M. C. & Shie, F. S., 2017 Dec 1, In : Journal of Cellular Physiology. 232, 12, p. 3409-3421 13 p.

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Thiourea
Derivatives
Calcium-Activated Potassium Channels
Tolbutamide
4 Citations (Scopus)

Synergistic inhibition of delayed rectifier K + and voltage-gated Na + currents by artemisinin in pituitary tumor (GH 3 ) cells

So, E. C., Wu, S-N., Wu, P-C., Chen, H. Z. & Yang, C. J., 2017 Jun 1, In : Cellular Physiology and Biochemistry. 41, 5, p. 2053-2066 14 p.

Research output: Contribution to journalArticle

Pituitary Neoplasms
Action Potentials
Iloprost
Neuroendocrine Cells
Endocrine Cells
2016
16 Citations (Scopus)

Estrogen ameliorates microglial activation by inhibiting the Kir2.1 inward-rectifier K+ channel

Wu, S. Y., Chen, Y. W., Tsai, S. F., Wu, S. N., Shih, Y. H., Jiang-Shieh, Y. F., Yang, T. T. & Kuo, Y. M., 2016 Mar 10, In : Scientific reports. 6, 22864.

Research output: Contribution to journalArticle

Inwardly Rectifying Potassium Channel
Estradiol
Dopaminergic Neurons
Estrogens
Parkinson Disease
8 Citations (Scopus)

Evidence for the Inhibition by Temozolomide, an Imidazotetrazine Family Alkylator, of Intermediate-Conductance Ca 2+ -Activated K + Channels in Glioma Cells

Yeh, P. S., Wu, S. J., Hung, T. Y., Huang, Y. M., Hsu, C. W., Sze, C-I., Hsieh, Y. J., Huang, C-W. & Wu, S-N., 2016 Jan 1, In : Cellular Physiology and Biochemistry. 38, 5, p. 1727-1742 16 p.

Research output: Contribution to journalArticle

temozolomide
Alkylating Agents
Glioma
Small Interfering RNA
Chlorzoxazone
10 Citations (Scopus)

Resveratrol attenuates cortical neuron activity: Roles of large conductance calcium-activated potassium channels and voltage-gated sodium channels

Wang, Y. J., Chan, M. H., Chen, L., Wu, S-N. & Chen, H. H., 2016 May 21, In : Journal of biomedical science. 23, 1, 47.

Research output: Contribution to journalArticle

Large-Conductance Calcium-Activated Potassium Channels
Voltage-Gated Sodium Channels
Neurons
Action Potentials
Sodium
2015
7 Citations (Scopus)

Actions of KMUP-1, a xanthine and piperazine derivative, on voltage-gated Na+ and Ca2+-activated K+ currents in GH3 pituitary tumour cells

Lo, Y. C., Tseng, Y. T., Liu, C. M., Wu, B. N. & Wu, S. N., 2015 Nov 1, In : British Journal of Pharmacology. 172, 21, p. 5110-5122 13 p.

Research output: Contribution to journalArticle

Xanthine
Pituitary Neoplasms
Ions
Calcium-Activated Potassium Channels
Architectural Accessibility
6 Citations (Scopus)

Arecoline inhibits intermediate-conductance calcium-activated potassium channels in human glioblastoma cell lines

So, E. C., Huang, Y. M., Hsing, C. H., Liao, Y. K. & Wu, S-N., 2015 Jul 5, In : European Journal of Pharmacology. 758, p. 177-187 11 p.

Research output: Contribution to journalArticle

Intermediate-Conductance Calcium-Activated Potassium Channels
Arecoline
Glioblastoma
Cell Line
Calcium-Activated Potassium Channels
26 Citations (Scopus)

Defined MicroRNAs Induce Aspects of Maturation in Mouse and Human Embryonic-Stem-Cell-Derived Cardiomyocytes

Lee, D. S., Chen, J. H., Lundy, D. J., Liu, C. H., Hwang, S. M., Pabon, L., Shieh, R. C., Chen, C. C., Wu, S. N., Yan, Y. T., Lee, S. T., Chiang, P. M., Chien, S., Murry, C. E. & Hsieh, P. C. H., 2015 Sep 29, In : Cell Reports. 12, 12, p. 1960-1967 8 p.

Research output: Contribution to journalArticle

Stem cells
MicroRNAs
Cardiac Myocytes
Embryonic Stem Cells
Endothelial cells

Evaluation of microvasculature at the auditory midbrain-the benefits of sectioning at a tangential angle

So, E. C., Lu, H. P., Hsing, C. H., Wu, S. N., Chang, Y. K. & Poon, P. W. F., 2015 Jan 1, In : Microscopy Research and Technique. 78, 1, p. 105-110 6 p.

Research output: Contribution to journalArticle

Inferior Colliculi
Mesencephalon
Microvessels
Blood Vessels
Brain
3 Citations (Scopus)

Inhibitory actions by ibandronate sodium, a nitrogen-containing bisphosphonate, on calcium-activated potassium channels in Madin-Darby canine kidney cells

Wu, S-N., Chen, H. Z., Chou, Y. H., Huang, Y. M. & Lo, Y. C., 2015 Aug 1, In : Toxicology Reports. 2, p. 1182-1193 12 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Madin Darby Canine Kidney Cells
Diphosphonates
Nitrogen
ibandronic acid
3 Citations (Scopus)

Investigations on contribution of glial inwardly-rectifying K+ current to membrane potential and ion flux: An experimental and theoretical study

Wu, S-N., Huang, Y. M., Kao, C. A., Chen, B. S. & Lo, Y. C., 2015 Jan 1, In : Kaohsiung Journal of Medical Sciences. 31, 1, p. 9-17 9 p.

Research output: Contribution to journalArticle

Neuroglia
Membrane Potentials
Theoretical Models
Ions
Neurons
1 Citation (Scopus)

Reversal by Ranolazine of Doxorubicin-Induced Prolongation in the Inactivation of Late Sodium Current in Rat Dorsal Root Ganglion Neurons

Wu, S. N., So, E. C., Liao, Y. K. & Huang, Y. M., 2015 May 1, In : Pain Medicine (United States). 16, 5, p. 1032-1034 3 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)
oxaliplatin
Platinum
Glioma
4 Citations (Scopus)

The inhibitory actions by lacosamide, a functionalized amino acid, on voltage-gated Na+ currents

Huang, C-W., Hung, T. Y. & Wu, S-N., 2015 Feb 6, In : Neuroscience. 287, p. 125-136 12 p.

Research output: Contribution to journalArticle

Amino Acids
lacosamide
Neurons
Convulsants
Drug Interactions
4 Citations (Scopus)
HSP90 Heat-Shock Proteins
Pancreatic Ducts
Cell Line
Epithelial Cells
Fluids and Secretions
2014
13 Citations (Scopus)
Motor Neurons
Flavonoids
Potassium
linopirdine
flupirtine
3 Citations (Scopus)
Intermediate-Conductance Calcium-Activated Potassium Channels
Diphosphonates
Osteoclasts
Nitrogen
Sodium
4 Citations (Scopus)

Effects of midazolam on ion currents and membrane potential in differentiated motor neuron-like NSC-34 and NG108-15 cells

So, E. C., Wu, K. C., Kao, F. C. & Wu, S. N., 2014 Feb 5, In : European Journal of Pharmacology. 724, 1, p. 152-160 9 p.

Research output: Contribution to journalArticle

Midazolam
Motor Neurons
Membrane Potentials
Ions
Action Potentials
3 Citations (Scopus)

High effectiveness of triptolide, an active diterpenoid triepoxide, in suppressing Kir-channel currents from human glioma cells

Cheung So, E., Lo, Y. C., Chen, L. T., Kao, C. A. & Wu, S. N., 2014 Sep 5, In : European Journal of Pharmacology. 738, p. 332-341 10 p.

Research output: Contribution to journalArticle

Diterpenes
Glioma
Ions
Inwardly Rectifying Potassium Channel
triptolide
2 Citations (Scopus)

Stimulation of electroporation-induced inward currents in glioblastoma cell lines by the heat shock protein inhibitor AUY922

Chiang, N. J., Wu, S-N., Kao, C. A., Huang, Y. M. & Chen, L. T., 2014 Oct 1, In : Clinical and Experimental Pharmacology and Physiology. 41, 10, p. 830-837 8 p.

Research output: Contribution to journalArticle

Electroporation
Glioblastoma
Heat-Shock Proteins
Cell Line
tanespimycin
2013
2 Citations (Scopus)

Identification of minuscule inward currents as precursors to membrane electroporation-induced currents: Real-time prediction of pore appearance

So, E. C., Tsai, K. L., Wu, F. T., Hsu, M. C., Wu, K. C. & Wu, S. N., 2013 Sep, In : Cellular Physiology and Biochemistry. 32, 2, p. 402-416 15 p.

Research output: Contribution to journalArticle

Electroporation
Principal Component Analysis
Membranes
Carnitine
Isoflurane