• 3636 Citations
  • 30 h-Index
1989 …2019
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Research Output 1989 2019

  • 3636 Citations
  • 30 h-Index
  • 206 Article
  • 5 Letter
  • 3 Review article
  • 1 Conference article
2000
14 Citations (Scopus)

Differential regulation of Ca2+ influx by fMLP and PAF in human neutrophils: Possible involvement of store-operated Ca2+ channel

Chen, L. W., Shen, A. Y., Chen, J. S. & Wu, S-N., 2000 Jan 1, In : Shock. 13, 3, p. 175-182 8 p.

Research output: Contribution to journalArticle

methionyl-leucyl-phenylalanine
Platelet Activating Factor
Neutrophils
Calcium Channels
Calcium
113 Citations (Scopus)

Evidence for the stimulatory effect of resveratrol on Ca2+-activated K+ current in vascular endothelial cells

Li, H. F., Chen, S. A. & Wu, S-N., 2000 Mar 1, In : Cardiovascular Research. 45, 4, p. 1035-1045 11 p.

Research output: Contribution to journalArticle

Endothelial Cells
Large-Conductance Calcium-Activated Potassium Channels
Islets of Langerhans
resveratrol
Bungarotoxins
18 Citations (Scopus)

Regulation of Ca2+-activated K+ currents by ciglitazone in rat pituitary GH3 cells

Wu, S-N., Ho, L. L. T., Li, H. F. & Chiang, H. T., 2000, In : Journal of Investigative Medicine. 48, 4, p. 259-269 11 p.

Research output: Contribution to journalArticle

Rats
Large-Conductance Calcium-Activated Potassium Channels
troglitazone
Peroxisome Proliferators
Clamping devices
19 Citations (Scopus)

Stimulatory effects of δ-hexachlorocyclohexane on Ca2+-activated K+ currents in GH3 lactotrophs

Wu, S-N., Li, H. F. & Chiang, H. T., 2000, In : Molecular Pharmacology. 57, 5, p. 865-873 9 p.

Research output: Contribution to journalArticle

Lactotrophs
Lindane
Large-Conductance Calcium-Activated Potassium Channels
Neuroblastoma
Aminobutyrates
18 Citations (Scopus)

The mechanism of actions of 3-(5'-(hydroxymethyl-2'-furyl)-1-benzyl indazole (YC-1) on Ca2+-activated K+ currents in GH3 lactotrophs

Wu, S-N., Hwang, T. L., Teng, C. M., Li, H. F. & Jan, C. R., 2000 Sep 1, In : Neuropharmacology. 39, 10, p. 1788-1799 12 p.

Research output: Contribution to journalArticle

Indazoles
Lactotrophs
Large-Conductance Calcium-Activated Potassium Channels
Egtazic Acid
Baths
1999
4 Citations (Scopus)

Activation of large-conductance Ca2+-activated K+ channels by pinacidil in human umbilical vascular endothelial cells

Wu, S-N., Li, H. F. & Shen, A. Y., 1999 Nov 10, In : Drug Development Research. 48, 1, p. 6-16 11 p.

Research output: Contribution to journalArticle

Pinacidil
Umbilicus
Calcium-Activated Potassium Channels
Endothelial Cells
Large-Conductance Calcium-Activated Potassium Channels
6 Citations (Scopus)

A further investigation of ATP-induced calcium mobilization in MDCK cells

Jan, C. R., Wu, S-N. & Tseng, C. J., 1999 Jan 1, In : Chinese Journal of Physiology. 42, 1, p. 33-39 7 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Adenosine Triphosphate
Calcium
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole
Econazole
34 Citations (Scopus)
Riluzole
Large-Conductance Calcium-Activated Potassium Channels
Rats
Calcium-Activated Potassium Channels
Neuroendocrine Cells
46 Citations (Scopus)

Inhibition of Ca2+-activated K+ current by clotrimazole in rat anterior pituitary GH3 cells

Wu, S-N., Li, H. F., Jan, C. R. & Shen, A. Y., 1999 Jul 1, In : Neuropharmacology. 38, 7, p. 979-989 11 p.

Research output: Contribution to journalArticle

Clotrimazole
Large-Conductance Calcium-Activated Potassium Channels
Econazole
Ketoconazole
Patch-Clamp Techniques
26 Citations (Scopus)

Mechanism of rise and decay of 2,5-di-tert-butylhydroquinone-induced Ca2+ signals in Madin Darby canine kidney cells

Jan, C. R., Ho, C. M., Wu, S-N. & Tseng, C. J., 1999 Jan 15, In : European Journal of Pharmacology. 365, 1, p. 111-117 7 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Endoplasmic Reticulum
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole
Thapsigargin
Oligomycins
49 Citations (Scopus)
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole
Madin Darby Canine Kidney Cells
Thapsigargin
Endoplasmic Reticulum
imidazole
46 Citations (Scopus)
Econazole
Thapsigargin
Calcium Signaling
Calcium
Fura-2
19 Citations (Scopus)

Ruthenium red-mediated inhibition of large-conductance Ca2+-activated K+ channels in rat pituitary GH3 cells

Wu, S-N., Jan, C. R. & Li, H. F., 1999 Sep 1, In : Journal of Pharmacology and Experimental Therapeutics. 290, 3, p. 998-1005 8 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Ruthenium Red
Large-Conductance Calcium-Activated Potassium Channels
Carbonyl Cyanide m-Chlorophenyl Hydrazone
Mitochondria
24 Citations (Scopus)

Stimulation of large-conductance Ca2+-activated K+ channels by Evans blue in cultured endothelial cells of human umbilical veins

Wu, S-N., Jan, C. R., Li, H. F. & Chen, S. A., 1999 Jan 27, In : Biochemical and Biophysical Research Communications. 254, 3, p. 666-674 9 p.

Research output: Contribution to journalArticle

Calcium-Activated Potassium Channels
Evans Blue
Umbilical Veins
Endothelial cells
Cultured Cells
53 Citations (Scopus)

Synthesis and cytotoxicity evaluation of some 8-hydroxyquinoline derivatives

Shen, A. Y., Wu, S-N. & Chiu, C. T., 1999 May, In : Journal of Pharmacy and Pharmacology. 51, 5, p. 543-548 6 p.

Research output: Contribution to journalArticle

Oxyquinoline
Mannich Bases
Cell Line
National Cancer Institute (U.S.)
Growth
20 Citations (Scopus)

The ether lipid ET-18-OCH3 increases cytosolic Ca2+ concentrations in Madin Darby canine kidney cells

Jan, C. R., Wu, S-N. & Tseng, C. J., 1999 Aug 10, In : British Journal of Pharmacology. 127, 6, p. 1502-1510 9 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Ether
Lipids
Thapsigargin
Phospholipase D
14 Citations (Scopus)

Zn2+ increases resting cytosolic Ca2+ levels and abolishes capacitative Ca2+ entry induced by ATP in MDCK cells

Jan, C. R., Wu, S-N. & Tseng, C. J., 1999 Jan 1, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 360, 3, p. 249-255 7 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Fura-2
Adenosine Triphosphate
Endoplasmic Reticulum
Fluorescence
1998
17 Citations (Scopus)

Activation of muscarinic K+ channels by extracellular ATP and UTP in rat atrial myocytes

Wu, S-N., Liu, S. I. & Hwang, T. L., 1998 Feb, In : Journal of Cardiovascular Pharmacology. 31, 2, p. 203-211 9 p.

Research output: Contribution to journalArticle

Uridine Triphosphate
Muscle Cells
Cholinergic Agents
Adenosine Triphosphate
Adenosine
81 Citations (Scopus)

Bradykinin-evoked Ca2+ mobilization in Madin Darby canine kidney cells

Jan, C. R., Ho, C. M., Wu, S-N. & Tseng, C. J., 1998 Aug 21, In : European Journal of Pharmacology. 355, 2-3, p. 219-233 15 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Bradykinin
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole
Protein Kinase Inhibitors
Lysosomes
36 Citations (Scopus)

Cardiovascular effects of nitric oxide and adenosine in the nucleus tractus solitarii of rats

Lo, W. C., Jan, C. R., Wu, S-N. & Tseng, C. J., 1998 Jan 1, In : Hypertension. 32, 6, p. 1034-1038 5 p.

Research output: Contribution to journalArticle

Solitary Nucleus
Adenosine
Nitric Oxide
Purinergic P1 Receptor Antagonists
Arginine
35 Citations (Scopus)

Cloning and functional expression of B chains of β-bungarotoxins from Bungarus multicinctus (Taiwan banded krait)

Wu, P. F., Wu, S-N., Chang, C. C. & Chang, L. S., 1998 Aug 15, In : Biochemical Journal. 334, 1, p. 87-92 6 p.

Research output: Contribution to journalArticle

Bungarus
Bungarotoxins
Cloning
Taiwan
Organism Cloning
9 Citations (Scopus)

Co-activation of Nonselective Cation Channels by Store Depletion and Oxidative Stress in Monocytic U937 Cells

Li, H. F., Shen, A. Y., Jan, C. R. & Wu, S-N., 1998 Jun 30, In : Chinese Journal of Physiology. 41, 2, p. 113-119 7 p.

Research output: Contribution to journalArticle

U937 Cells
Cations
Oxidative Stress
Inositol 1,4,5-Trisphosphate
Thapsigargin
38 Citations (Scopus)

Correlation of hepatocyte growth factor-induced proliferation and calcium-activated potassium current in human gastric cancer cells

Liu, S. I., Chi, C. W., Lui, W. Y., Mok, K. T., Wu, C. W. & Wu, S-N., 1998 Jan 19, In : Biochimica et Biophysica Acta - Biomembranes. 1368, 2, p. 256-266 11 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Stomach Neoplasms
Potassium
Cells
Calcium
5 Citations (Scopus)

Effects of 1-pyrrolidinylmethyl-2-naphthol on contractile force and ionic current in cardiac and vascular smooth myocytes

Shen, A. Y. & Wu, S-N., 1998 Jun 1, In : Drug Development Research. 44, 2-3, p. 87-96 10 p.

Research output: Contribution to journalArticle

Vascular Smooth Muscle
Muscle Cells
Smooth Muscle Myocytes
Blood Vessels
Muscle
44 Citations (Scopus)

Inhibitory effects of berberine on voltage- and calcium-activated potassium currents in human myeloma cells

Wu, S-N., Yu, H. S., Jan, C. R., Li, H. F. & Yu, C. L., 1998 May 15, In : Life Sciences. 62, 25, p. 2283-2294 12 p.

Research output: Contribution to journalArticle

Berberine
Potassium
Calcium
Electric potential
Inhibitory Concentration 50
11 Citations (Scopus)

La 3+ Inhibits the UTP-induced Ca 2+ Mobilization in MDCK Cells

Jan, C. R., Ho, C. M., Wu, S-N., Huang, J. K. & Tseng, C. J., 1998 Mar 31, In : Chinese Journal of Physiology. 41, 1, p. 59-64 6 p.

Research output: Contribution to journalArticle

Uridine Triphosphate
Madin Darby Canine Kidney Cells
Fluorometry
Inositol 1,4,5-Trisphosphate
Thapsigargin
81 Citations (Scopus)

Mechanism of lanthanum inhibition of extracellular ATP-evoked calcium mobilization in MDCK cells

Jan, C. R., Ho, C. M., Wu, S-N., Huang, J. K. & Tseng, C. J., 1998 Jan 2, In : Life Sciences. 62, 6, p. 533-540 8 p.

Research output: Contribution to journalArticle

Lanthanum
Madin Darby Canine Kidney Cells
Adenosine Triphosphate
Calcium
Purinergic P2 Receptors
61 Citations (Scopus)

Mechanism of rise and decay of thapsigargin-evoked calcium signals in MDCK cells

Jan, C. R., Ho, C. M., Wu, S-N. & Tseng, C. J., 1998 Dec 18, In : Life Sciences. 64, 4, p. 259-267 9 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Thapsigargin
Calcium
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole
Econazole
7 Citations (Scopus)

Mechanisms of Rise and Decay of ADP-Evoked Calcium Signal in MDCK Cells

Jan, C. R., Ho, C. M., Wu, S-N. & Tseng, C. J., 1998 Jun 30, In : Chinese Journal of Physiology. 41, 2, p. 67-73 7 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Adenosine Diphosphate
Calcium
Adenosine Triphosphate
Fluorometry
10 Citations (Scopus)

Nifedipine, verapamil and diltiazem block shock-wave-induced rises in cytosolic calcium in MDCK cells

Jan, C. R., Chen, W. C., Wu, S-N. & Tseng, C. J., 1998 Jan 1, In : Chinese Journal of Physiology. 41, 4, p. 181-188 8 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Diltiazem
Nifedipine
Transferases
Verapamil

Potentiation of muscarinic K+ channel activity by PD 81,723 in rat atrial myocytes

Wu, S-N., Lee, H. F. & Tseng, C. J., 1998 Mar 20, In : FASEB Journal. 12, 5

Research output: Contribution to journalArticle

potassium channels
adenosine
myocytes
Muscle Cells
Cholinergic Agents
24 Citations (Scopus)

Regulation of Ca2+-activated nonselective cationic currents in rat pituitary GH3 cells: Involvement in L-type Ca2+ current

Wu, S-N., Li, H. F. & Jan, C. R., 1998 Nov 23, In : Brain Research. 812, 1-2, p. 133-141 9 p.

Research output: Contribution to journalArticle

Tail
tetrandrine
Egtazic Acid
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
Patch-Clamp Techniques
8 Citations (Scopus)

Selective block by glyceryl nonivamide of inwardly rectifying K+ current in rat anterior pituitary GH3 cells

Wu, S-N., Li, H. F., Jan, C. R., Chen, I. J. & Lo, Y. C., 1998 Oct 2, In : Life Sciences. 63, 19, p. PL281-PL288

Research output: Contribution to journalArticle

Rats
N-(4-O-glycerol-3-methoxybenzyl)nonivamide
Neurons
Electric potential
49 Citations (Scopus)

The phospholipase C inhibitor U73122 increases cytosolic calcium in MDCK cells by activating calcium influx and releasing stored calcium

Jan, C. R., Ho, C. M., Wu, S-N. & Tseng, C. J., 1998 Jul 31, In : Life Sciences. 63, 10, p. 895-908 14 p.

Research output: Contribution to journalArticle

Madin Darby Canine Kidney Cells
Type C Phospholipases
Calcium
Endoplasmic Reticulum
Mitochondria
1997
9 Citations (Scopus)

Characteristics of Store-Operated Ca 2+ -Permeable Current in Monocytic U937 Cells

Wu, S-N., Jan, C. R. & Li, H. F., 1997 Jan 1, In : Chinese Journal of Physiology. 40, 3, p. 115-120 6 p.

Research output: Contribution to journalArticle

U937 Cells
Nifedipine
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
Architectural Accessibility
Calcimycin
8 Citations (Scopus)

Differential effects of adenosine on antegrade and retrograde fast pathway conduction in atrioventricular nodal reentry

Lee, C. S., Lai, W. T., Wu, J. C., Sheu, S. H., Wu, S-N. & Belardinelli, L., 1997 Jan 1, In : American Heart Journal. 134, 5 I, p. 799-806 8 p.

Research output: Contribution to journalArticle

Adenosine
Verapamil
Atrioventricular Block
Atrioventricular Nodal Reentry Tachycardia
Catheter Ablation
16 Citations (Scopus)
Calcitonin Gene-Related Peptide
Capsaicin
Vasodilator Agents
Aorta
Guinea Pigs
8 Citations (Scopus)

Influence of beta-adrenergic and vagal activity on the effect of exogenous adenosine on supraventricular tachycardia termination

Tai, C. T., Chen, S. A., Chiang, C. E., Lee, S. H., Wen, Z. C., Chang, M. S. & Wu, S-N., 1997 Jun 15, In : American Journal of Cardiology. 79, 12, p. 1628-1631 4 p.

Research output: Contribution to journalArticle

Supraventricular Tachycardia
Adrenergic Agents
Adenosine
Atropine
Isoproterenol
25 Citations (Scopus)

ionic mechanisms of tetradrine in cultured rat aortic smooth muscle cells

Wu, S-N., Hwang, T. L., Jan, C. R. & Tseng, C. J., 1997 May 30, In : European Journal of Pharmacology. 327, 2-3, p. 233-238 6 p.

Research output: Contribution to journalArticle

tetrandrine
Smooth Muscle Myocytes
Vascular Smooth Muscle
Stephania
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
1996
14 Citations (Scopus)

Analysis of Mechanical Restitution and Post-rest Potentiation in Isolated Rat Atrium

Wu, S-N., Shen, A. Y. & Hwang, T. L., 1996 Jan 1, In : Chinese Journal of Physiology. 39, 1, p. 23-29 7 p.

Research output: Contribution to journalArticle

Sarcoplasmic Reticulum
Myocardium
Ryanodine
Verapamil
Isoproterenol
12 Citations (Scopus)

Analytical studies of spontaneous and vasopressin-induced calcium oscillations in cultured vascular smooth muscle cells

Wu, S-N., Yu, H. S. & Seyama, Y., 1996 Jan 1, In : Journal of biochemistry. 119, 1, p. 42-48 7 p.

Research output: Contribution to journalArticle

Calcium Signaling
Vasopressins
Vascular Smooth Muscle
Smooth Muscle Myocytes
Muscle
6 Citations (Scopus)

Effects of verapamil, propranolol, and procainamide on adenosine- induced negative dromotropism in human beings

Lai, W. T., Lee, C. S., Wu, J. C., Sheu, S. H. & Wu, S-N., 1996 Jan 1, In : American Heart Journal. 132, 4, p. 768-775 8 p.

Research output: Contribution to journalArticle

Procainamide
Verapamil
Propranolol
Adenosine
Atrioventricular Block
47 Citations (Scopus)

Endothelin-1 and vasopressin activate Ca 2+ -permeable non-selective cation channels in aortic smooth muscle cells: Mechanism of receptor-mediated Ca 2+ influx

Nakajima, T., Hazama, H., Hamada, E., Wu, S-N., Igarashi, K., Yamashita, T., Seyama, Y., Omata, M. & Kurachi, Y., 1996 Jan 1, In : Journal of Molecular and Cellular Cardiology. 28, 4, p. 707-722 16 p.

Research output: Contribution to journalArticle

Endothelin-1
Vasopressins
Smooth Muscle Myocytes
Cations
Calcium
9 Citations (Scopus)

The characteristics in the inhibitory effects of capsaicin on voltage-dependent K+ currents in rat atrial myocytes

Wu, S-N., Chen, I. J., Lo, Y. C. & Yu, H. S., 1996 Aug 15, In : Environmental Toxicology and Pharmacology. 2, 1, p. 39-47 9 p.

Research output: Contribution to journalArticle

Capsaicin
Muscle Cells
Rats
Electric potential
Clamping devices
32 Citations (Scopus)
Chloride Channels
Primary Cell Culture
Uterine Cervical Neoplasms
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
Carcinoma
1995
14 Citations (Scopus)

Induction of Ca2+ oscillations by vasopressin in the presence of tetraethylammonium chloride in cultured vascular smooth muscle cells

Wu, S-N., Yu, H. S. & Seyama, Y., 1995 Feb 1, In : Journal of biochemistry. 117, 2, p. 309-314 6 p.

Research output: Contribution to journalArticle

Tetraethylammonium
Vasopressins
Vascular Smooth Muscle
Smooth Muscle Myocytes
Muscle
7 Citations (Scopus)
Smooth Muscle Myocytes
Potassium
Ethanol
Vasoconstrictor Agents
Patch-Clamp Techniques
57 Citations (Scopus)

Volume-sensitive Chloride Channels Associated with Human Cervical Carcinogenesis

Chou, C-Y., Shen, M-R. & Wu, S-N., 1995 Dec 15, In : Cancer Research. 55, 24, p. 6077-6083 7 p.

Research output: Contribution to journalArticle

Chloride Channels
Chlorides
Carcinogenesis
Carcinoma in Situ
Cervical Intraepithelial Neoplasia
1994

Halothane myocardial depression [5]

Wu, S-N. & Nakajima, T., 1994 Jan 1, In : Anesthesia and analgesia. 78, 2, p. 406-407 2 p.

Research output: Contribution to journalLetter

Chemical Depression
Myocardial Contraction
Halothane
Sprague Dawley Rats
Rabbits
32 Citations (Scopus)

Molecular mechanism of cibenzoline-induced anticholinergic action in single atrial myocytes: Comparison with effect of disopyramide

Wu, S-N., Nakajima, T., Yamashita, T., Hamada, E., Hazama, H., Iwasawa, K., Omata, M. & Kurachi, Y., 1994 Jan 1, In : Journal of Cardiovascular Pharmacology. 23, 4, p. 618-623 6 p.

Research output: Contribution to journalArticle

Disopyramide
Cholinergic Antagonists
Guanosine Triphosphate
Muscle Cells
Guanosine 5'-O-(3-Thiotriphosphate)