• 908 Citations
  • 17 h-Index
20052019
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Research Output 2005 2019

  • 908 Citations
  • 17 h-Index
  • 29 Article
  • 1 Comment/debate
  • 1 Review article
2019
2 Citations (Scopus)
Cell Hypoxia
Stromal Cells
Apoptosis
Endometriosis
Oxygen Consumption
1 Citation (Scopus)

Targeting anthrax toxin receptor 2 ameliorates endometriosis progression

Lin, S. C., Lee, H. C., Hsu, C. T., Huang, Y. H., Li, W. N., Hsu, P. L., Wu, M. H. & Tsai, S. J., 2019 Jan 1, In : Theranostics. 9, 3, p. 620-632 13 p.

Research output: Contribution to journalArticle

Open Access
Endometriosis
Histone Code
Choristoma
Pathologic Processes
Stromal Cells
2018
8 Citations (Scopus)

Genes involved in prostate cancer progression determine MRI visibility

Li, P., You, S., Nguyen, C., Wang, Y., Kim, J., Sirohi, D., Ziembiec, A., Luthringer, D., Lin, S. C., Daskivich, T., Wu, J., Freeman, M. R., Saouaf, R., Li, D. & Kim, H. L., 2018 Jan 1, In : Theranostics. 8, 7, p. 1752-1765 14 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Genes
Heterografts
Disease Progression
Neoplasms
1 Citation (Scopus)

MicroRNA expression pattern as an ancillary prognostic signature for radiotherapy 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

Li, A. L., Chung, T. S., Chan, Y. N., Chen, C. L., Lin, S-C., Chiang, Y. R., Lin, C. H., Chen, C. C. & Ma, N., 2018 Dec 5, In : Journal of Translational Medicine. 16, 1, 341.

Research output: Contribution to journalArticle

Open Access
Oncology
Radiotherapy
MicroRNAs
Carcinogenesis
Health
2017
5 Citations (Scopus)

Dysregulation of nuclear receptor COUP-TFII impairs skeletal muscle development

Lee, H. J., Kao, C. Y., Lin, S-C., Xu, M., Xie, X., Tsai, S. Y. & Tsai, M. J., 2017 Dec 1, In : Scientific reports. 7, 1, 3136.

Research output: Contribution to journalArticle

COUP Transcription Factor II
Muscle Development
Cytoplasmic and Nuclear Receptors
Skeletal Muscle
Cell Fusion
22 Citations (Scopus)

Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness

Hou, P. C., Li, Y. H., Lin, S. C., Lin, S. C., Lee, J. C., Lin, B. W., Liou, J. P., Chang, J. Y., Kuo, C. C., Liu, Y. M., Sun, H. S. & Tsai, S. J., 2017 Aug 15, In : Cancer Research. 77, 16, p. 4305-4316 12 p.

Research output: Contribution to journalArticle

Dual-Specificity Phosphatases
Dual Specificity Phosphatase 2
Colonic Neoplasms
Down-Regulation
Neoplasms
6 Citations (Scopus)

Hypoxia-inhibited DUSP2 expression promotes IL-6/STAT3 signaling in endometriosis

Hsiao, K. Y., Chang, N., Tsai, J. L., Lin, S-C., Tsai, S-J. & Wu, M-H., 2017 Jan 1, In : American Journal of Reproductive Immunology. 78, 4, e12690.

Research output: Contribution to journalArticle

Dual Specificity Phosphatase 2
Endometriosis
Interleukin-6
Stromal Cells
Bromodeoxyuridine
11 Citations (Scopus)

Loss of dual-specificity phosphatase-2 promotes angiogenesis and metastasis via up-regulation of interleukin-8 in colon cancer

Lin, S-C., Hsiao, K. Y., Chang, N., Hou, P. C. & Tsai, S-J., 2017 Apr 1, In : Journal of Pathology. 241, 5, p. 638-648 11 p.

Research output: Contribution to journalArticle

Dual Specificity Phosphatase 2
Interleukin-8
Colonic Neoplasms
Up-Regulation
Neoplasm Metastasis
6 Citations (Scopus)
Endometriosis
Nuclear Proteins
Fertility
Mothers
Proteins
2016
32 Citations (Scopus)

Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer

Lin, S. C., Kao, C. Y., Lee, H. J., Creighton, C. J., Ittmann, M. M., Tsai, S. J., Tsai, S. Y. & Tsai, M. J., 2016 Apr 25, In : Nature communications. 7, 11418.

Research output: Contribution to journalArticle

metastasis
MicroRNAs
Prostatic Neoplasms
cancer
Neoplasm Metastasis
23 Citations (Scopus)

MPC1, a key gene in cancer metabolism, is regulated by COUP-TFII in human prostate cancer

Wang, L., Xu, M., Qin, J., Lin, S-C., Lee, H. J., Tsai, S. Y. & Tsai, M. J., 2016 Mar 22, In : Oncotarget. 7, 12, p. 14673-14683 11 p.

Research output: Contribution to journalArticle

COUP Transcription Factor II
Neoplasm Genes
Prostatic Neoplasms
Glycolysis
Neoplasms
3 Citations (Scopus)

Peroxisome proliferator-activated receptor γ level contributes to structural integrity and component production of elastic fibers in the aorta

Tai, H. C., Tsai, P. J., Chen, J. Y., Lai, C. H., Wang, K. C., Teng, S. H., Lin, S. C., Chang, A. Y. W., Jiang, M. J., Li, Y. H., Wu, H. L., Maeda, N. & Tsai, Y. S., 2016 Jun 1, In : Hypertension. 67, 6, p. 1298-1308 11 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Elastic Tissue
Abdominal Aortic Aneurysm
Aorta
Angiotensin II
1 Citation (Scopus)

Quantitative PPARγ expression affects the balance between tolerance and immunity

Liu, Y. H., Tsai, Y. S., Lin, S. C., Liao, N. S., Jan, M. S., Liang, C. T., Hsu, S. W., Chen, W. C., Sung, J. M., Maeda, N. & Tsai, P. J., 2016 May 25, In : Scientific reports. 6, 26646.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Immunity
Lysosphingolipid Receptors
B-Lymphocytes
Spleen
17 Citations (Scopus)

Targeting TYRO3 inhibits epithelial-mesenchymal transition and increases drug sensitivity in colon cancer

Chien, C. W., Hou, P. C., Wu, H. C., Chang, Y. L., Lin, S. C., Lin, S. C., Lin, B. W., Lee, J. C., Chang, Y. J., Sun, H. S. & Tsai, S. J., 2016 Nov 10, In : Oncogene. 35, 45, p. 5872-5881 10 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Colonic Neoplasms
Pharmaceutical Preparations
Oncogenes
Antibodies
2015
21 Citations (Scopus)

MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy

Hsu, T. I., Lin, S. C., Lu, P. S., Chang, W. C., Hung, C. Y., Yeh, Y. M., Su, W. C., Liao, P. C. & Hung, J. J., 2015 Feb 12, In : Oncogene. 34, 7, p. 826-837 12 p.

Research output: Contribution to journalArticle

Neoplasms
Lung Neoplasms
RNA Stability
nucleolin
Matrix Metalloproteinase 7
16 Citations (Scopus)

Pathological functions of hypoxia in endometriosis

Hsiao, K. Y., Lin, S-C., Wu, M-H. & Tsai, S-J., 2015 Jan 1, In : Frontiers in bioscience (Elite edition). 7, p. 309-321 13 p.

Research output: Contribution to journalReview article

Endometriosis
Cyclooxygenase 2
Dinoprostone
Estrogens
Genes
2 Citations (Scopus)

Pathological functions of hypoxia in endometriosis

Hsiao, K. Y., Lin, S-C., Wu, M-H. & Tsai, S-J., 2015 Jan 15, In : Frontiers in Bioscience - Elite. 7E, 2, p. 352-366 15 p.

Research output: Contribution to journalArticle

Endometriosis
Cyclooxygenase 2
Dinoprostone
Estrogens
Genes
2014
36 Citations (Scopus)

Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer

Qin, J., Lee, H. J., Wu, S. P., Lin, S. C., Lanz, R. B., Creighton, C. J., DeMayo, F. J., Tsai, S. Y. & Tsai, M. J., 2014 Nov 3, In : Journal of Clinical Investigation. 124, 11, p. 5013-5026 14 p.

Research output: Contribution to journalArticle

Castration
Androgens
Prostatic Neoplasms
Neoplasms
Phosphatidylinositol 3-Kinases
30 Citations (Scopus)

Inhibition of dual specificity phosphatase-2 by hypoxia promotes interleukin-8-mediated angiogenesis in endometriosis

Hsiao, K. Y., Chang, N., Lin, S. C., Li, Y. H. & Wu, M. H., 2014 Jun 26, In : Human Reproduction. 29, 12, p. 2747-2755 9 p.

Research output: Contribution to journalArticle

Dual Specificity Phosphatase 2
Endometriosis
Interleukin-8
Stromal Cells
Interleukin-8 Receptors
18 Citations (Scopus)

Suppression of COUP-TFII by proinflammatory cytokines contributes to the pathogenesis of endometriosis

Lin, S. C., Li, Y. H., Wu, M. H., Chang, Y. F., Lee, D. K., Tsai, S. Y., Tsai, M. J. & Tsai, S. J., 2014 Mar, In : Journal of Clinical Endocrinology and Metabolism. 99, 3, p. E427-E437

Research output: Contribution to journalArticle

COUP Transcription Factor II
Endometriosis
Cytokines
Cyclooxygenase 2
Stromal Cells
2013
2 Citations (Scopus)
Transcription factors
Transcription Factors
Genes
Gene expression
Pattern recognition
2012
74 Citations (Scopus)
Phosphorylation
Stromal Cells
MicroRNAs
Gene expression
Gene Expression
2011
32 Citations (Scopus)

Hypoxia-inhibited dual-specificity phosphatase-2 expression in endometriotic cells regulates cyclooxygenase-2 expression

Wu, M-H., Lin, S-C., Hsiao, K. Y. & Tsai, S-J., 2011 Nov 1, In : Journal of Pathology. 225, 3, p. 390-400 11 p.

Research output: Contribution to journalArticle

Dual Specificity Phosphatase 2
Cyclooxygenase 2
Stromal Cells
Hypoxia-Inducible Factor 1
Extracellular Signal-Regulated MAP Kinases
64 Citations (Scopus)

Overexpression of pyruvate dehydrogenase kinase 3 increases drug resistance and early recurrence in colon cancer

Lu, C. W., Lin, S-C., Chien, C. W., Lin, S-C., Lee, C-T., Lin, P-W., Lee, J-C. & Tsai, S-J., 2011 Sep 1, In : American Journal of Pathology. 179, 3, p. 1405-1414 10 p.

Research output: Contribution to journalArticle

Drug Resistance
Colonic Neoplasms
Recurrence
Neoplasms
Hypoxia-Inducible Factor 1
52 Citations (Scopus)

Suppression of dual-specificity phosphatase-2 by hypoxia increases chemoresistance and malignancy in human cancer cells

Lin, S. C., Chien, C. W., Lee, J. C., Yeh, Y. C., Hsu, K. F., Lai, Y. Y., Lin, S. C. & Tsai, S. J., 2011 May 2, In : Journal of Clinical Investigation. 121, 5, p. 1905-1916 12 p.

Research output: Contribution to journalArticle

Dual Specificity Phosphatase 2
Hypoxia-Inducible Factor 1
Neoplasms
Dual Specificity Phosphatase 1
Hypoxia
2010
81 Citations (Scopus)
Epithelial-Mesenchymal Transition
Transforming Growth Factors
Integrins
Fibrosis
Gene Expression
2008
185 Citations (Scopus)

Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance

Lu, C. W., Lin, S. C., Chen, K. F., Lai, Y. Y. & Tsai, S. J., 2008 Oct 17, In : Journal of Biological Chemistry. 283, 42, p. 28106-28114 9 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Drug Resistance
Switches
Cells
Assays
45 Citations (Scopus)

Regulation of CD151 by hypoxia controls cell adhesion and metastasis in colorectal cancer

Chien, C. W., Lin, S. C., Lai, Y. Y., Lin, B. W., Lin, S. C., Lee, J. C. & Tsai, S. J., 2008 Dec 15, In : Clinical Cancer Research. 14, 24, p. 8043-8051 9 p.

Research output: Contribution to journalArticle

Cell Adhesion
Colorectal Neoplasms
Neoplasm Metastasis
Neoplasms
Hypoxia-Inducible Factor 1
2007
77 Citations (Scopus)
Hypoxia-Inducible Factor 1
Stromal Cells
Leptin
Endometriosis
Gene Expression
34 Citations (Scopus)
Functional analysis
Leiomyoma
Pituitary Neoplasms
Transforming Growth Factors
Oncogenes