Shih-Huang Chan

Associate Professor

  • 1218 Citations
  • 20 h-Index
1991 …2018
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Research Output 1991 2018

  • 1218 Citations
  • 20 h-Index
  • 39 Article
  • 1 Conference contribution
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Article
2018

Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection

Yen, C., Ai, Y., Tsai, H., Chan, S., Yen, C., Cheng, K., Lee, Y., Kao, C., Wang, Y., Chen, Y., Lin, C., Liu, T., Tsai, H., Wang, J., Su, I. & Huang, W., 2018 Sep 1, In : Hepatology. 68, 3, p. 815-826

Research output: Contribution to journalArticle

5 Citations (Scopus)

Hepatitis B virus surface gene pre-S 2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection

Yen, C-J., Ai, Y. L., Tsai, H-W., Chan, S-H., Yen, C. S., Cheng, K. H., Lee, Y. P., Kao, C. W., Wang, Y. C., Chen, Y. L., Lin, C. H., Liu, T., Tsai, H. P., Wang, J-R., Su, I. J. & Huang, W-Y., 2018 Sep 1, In : Hepatology. 68, 3, p. 815-826 12 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Biomarkers
Recurrence
Surface Antigens
1 Citation (Scopus)

NEK2 promotes hepatoma metastasis and serves as biomarker for high recurrence risk after hepatic resection

Chang, Y. Y., Yen, C-J., Chan, S-H., Chou, Y. W., Lee, Y. P., Bao, C. Y., Huang, C. J. & Huang, W-Y., 2018 Sep 1, In : Annals of Hepatology. 17, 5, p. 843-856 14 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Biomarkers
Neoplasm Metastasis
Recurrence
Liver

NEK2 Promotes Hepatoma Metastasis and Serves as Biomarker for High Recurrence Risk after Hepatic Resection

Chang, Y., Yen, C., Chan, S., Chou, Y., Lee, Y., Bao, C., Huang, C. & Huang, W., 2018 Aug 24, In : Annals of Hepatology. 17, 5, p. 843-856

Research output: Contribution to journalArticle

1 Citation (Scopus)

Progesterone receptor membrane component 1 as a potential prognostic biomarker for hepatocellular carcinoma

Tsai, H-W., Ho, C-L., Cheng, S. W., Lin, Y-J., Chen, C. C., Cheng, P-N., Yen, C-J., Chang, T-T., Chiang, P-M., Chan, S-H., Ho, C. H., Chen, S-H., Wang, Y. W., Chow, N-H. & Lin, J. C., 2018 Mar 14, In : World journal of gastroenterology. 24, 10, p. 1152-1166 15 p.

Research output: Contribution to journalArticle

Progesterone Receptors
Hepatocellular Carcinoma
Biomarkers
Membranes
Atlases
2016
6 Citations (Scopus)
Chronic Hepatitis B
Antiviral Agents
Glass
Hepatocytes
Hepatocellular Carcinoma
2013
30 Citations (Scopus)

Lin28B is an oncofetal circulating cancer stem cell-like marker associated with recurrence of hepatocellular carcinoma

Cheng, S. W., Tsai, H-W., Lin, Y-J., Cheng, P-N., Chang, Y. C., Yen, C-J., Huang, H. P., Chuang, Y. P., Chang, T-T., Lee, C-T., Chao, A., Chou, C-Y., Chan, S-H., Chow, N-H. & Ho, C-L., 2013 Nov 14, In : PLoS ONE. 8, 11, e80053.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
hepatoma
Stem cells
stem cells
Tumors
2011
38 Citations (Scopus)

A clustered ground-glass hepatocyte pattern represents a new prognostic marker for the recurrence of hepatocellular carcinoma after surgery

Tsai, H-W., Lin, Y-J., Lin, P. W., Wu, H. C., Hsu, K. H., Yen, C-J., Chan, S-H., Huang, W-Y. & Su, I. J., 2011 Jul 1, In : Cancer. 117, 13, p. 2951-2960 10 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Glass
Hepatocytes
Hepatocellular Carcinoma
Hepatitis B Surface Antigens
2009
1 Citation (Scopus)

A robust ratio estimator of gene expression via inverse-variance weighting for cDNA microarray images

Chan, S-H. & Chang, W. C., 2009 Mar 15, In : Computational Statistics and Data Analysis. 53, 5, p. 1577-1589 13 p.

Research output: Contribution to journalArticle

CDNA Microarray
Ratio Estimator
Robust Estimators
Microarrays
Gene expression
2007
33 Citations (Scopus)

Prohibitin in the pathogenesis of transitional cell bladder cancer

Wu, T. F., Wu, H., Wang, Y. W., Chang, T. Y., Chan, S-H., Lin, Y. P., Liu, H-S. & Chow, N-H., 2007 Mar 1, In : Anticancer Research. 27, 2, p. 895-900 6 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Carcinogenesis
Neoplasms
prohibitin
Genistein
2006
20 Citations (Scopus)

Genetic polymorphisms in CYP1A1 and GSTM1 predispose humans to PCBs/PCDFs-induced skin lesions

Tsai, P. C., Huang, W-Y., Lee, Y. C., Chan, S-H. & Guo, Y. L., 2006 May 1, In : Chemosphere. 63, 8, p. 1410-1418 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP1A1
Polychlorinated Biphenyls
dibenzofuran
Genetic Polymorphisms
Polymorphism
2005
2 Citations (Scopus)
Microarrays
Genes
Acoustic waves
Urinary Bladder Neoplasms
Real-Time Polymerase Chain Reaction
40 Citations (Scopus)

Nasopharyngeal carcinoma-susceptibility locus is localized to a 132 kb segment containing HLA-A using high-resolution microsatellite mapping

Lu, C-C., Chen, J. C., Tsai, S-T., Jin, Y. T., Tsai, J-C., Chan, S-H. & Su, I. J., 2005 Jul 10, In : International Journal of Cancer. 115, 5, p. 742-746 5 p.

Research output: Contribution to journalArticle

HLA-A Antigens
Microsatellite Repeats
Genes
HLA-A2 Antigen
Nasopharyngeal carcinoma
2003
19 Citations (Scopus)

Clinical significance of allelotype profiling for urothelial carcinoma

Tzai, T. S., Chen, H. H. W., Chan, S-H., Ho, C-L., Tsai, Y-S., Cheng, H-L., Dai, Y. C., Lin, J. S. N., Yang, W-H. & Chow, N-H., 2003 Aug 1, In : Urology. 62, 2, p. 378-384 7 p.

Research output: Contribution to journalArticle

Loss of Heterozygosity
Carcinoma
Carcinogenesis
Chromosomes
Survival
56 Citations (Scopus)

Genetic susceptibility to nasopharyngeal carcinoma within the HLA-A locus in Taiwanese

Lu, C-C., Chen, J. C., Jin, Y. T., Yang, H. B., Chan, S-H. & Tsai, S-T., 2003 Mar 1, In : International Journal of Cancer. 103, 6, p. 745-751 7 p.

Research output: Contribution to journalArticle

HLA-A Antigens
Genetic Predisposition to Disease
varespladib methyl
Population
Genes
2002
67 Citations (Scopus)
Transitional Cell Carcinoma
Urinary Bladder
Urinary Bladder Neoplasms
Neoplasms
Proto-Oncogenes
2001
23 Citations (Scopus)

Education and cognitive decline in parkinson's disease: A study of 102 patients

Pai, M-C. & Chan, S-H., 2001 Apr 26, In : Acta Neurologica Scandinavica. 103, 4, p. 243-247 5 p.

Research output: Contribution to journalArticle

Parkinson Disease
Education
Cognition
Language
Aptitude
198 Citations (Scopus)
Transitional Cell Carcinoma
Epidermal Growth Factor Receptor
Urinary Bladder
Urinary Bladder Neoplasms
Survival
2000
12 Citations (Scopus)

The clinical value of p21(WAF1/CIP1) expression in superficial bladder cancer

Chow, N-H., Tzai, T. S., Cheng, H-L., Liu, H-S., Chan, S-H. & Tong, Y-C., 2000 Jan 1, In : Anticancer Research. 20, 2 B, p. 1173-1176 4 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Neoplasms
Survival
p53 Genes
Disease Progression
26 Citations (Scopus)

The role of nm23-H1 in the progression of transitional cell bladder cancer

Chow, N-H., Liu, H-S. & Chan, S-H., 2000, In : Clinical Cancer Research. 6, 9, p. 3595-3599 5 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Neoplasms
Neoplasm Metastasis
Survival
Tumor Suppressor Genes
1999
36 Citations (Scopus)

Expression of vascular endothelial growth factor in primary superficial bladder cancer

Chow, N-H., Liu, H-S., Chan, S-H., Cheng, H-L. & Tzai, T. S., 1999, In : Anticancer Research. 19, 5 C, p. 4593-4597 5 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Vascular Endothelial Growth Factor A
Neoplasms
Urothelium
Mucous Membrane
28 Citations (Scopus)

The role of bcl-2 in the progression of the colorectal adenoma-carcinoma sequence

Yang, H. B., Chow, N-H., Sheu, B-S., Chan, S-H., Chien, C. H. & Su, I. J., 1999 Apr 20, In : Anticancer research. 19, 1 B, p. 727-730 4 p.

Research output: Contribution to journalArticle

Adenoma
Colorectal Neoplasms
Adenocarcinoma
Proto-Oncogenes
Mucous Membrane
1998
21 Citations (Scopus)
Fibroblast Growth Factor 1
Fibroblast Growth Factor 2
Hepatocellular Carcinoma
Liver
Angiogenesis Inducing Agents
1997
1 Citation (Scopus)

Effect of Thyroid Hormone on Urinary Excretion of Epidermal Growth Factor

Huang, S-M., Chan, S-H., Wu, T. J. & Chow, N-H., 1997 Jan 1, In : European Surgical Research. 29, 3, p. 222-228 7 p.

Research output: Contribution to journalArticle

Thyroid Hormones
Epidermal Growth Factor
Thyrotropin
Thyroxine
Serum
107 Citations (Scopus)

Expression of vascular endothelial growth factor in normal liver and hepatocellular carcinoma: An immunohistochemical study

Chow, N-H., Hsu, P. I., Lin, X-Z., Yang, H. B., Chan, S-H., Cheng, K-S., Huang, S-M. & Su, I. J., 1997 Jan 1, In : Human Pathology. 28, 6, p. 698-703 6 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Hepatocellular Carcinoma
Liver
Portal Vein
Extracellular Matrix
57 Citations (Scopus)

Expression patterns of erbB receptor family in normal urothelium and transitional cell carcinoma. An immunohistochemical study

Chow, N-H., Liu, H-S., Yang, H. B., Chan, S-H. & Su, I. J., 1997 Aug 14, In : Virchows Archiv. 430, 6, p. 461-466 6 p.

Research output: Contribution to journalArticle

Urothelium
Transitional Cell Carcinoma
Epidermal Growth Factor Receptor
Carcinogenesis
Ki-67 Antigen
40 Citations (Scopus)

Implications of serum basic fibroblast growth factor levels in chronic liver diseases and hepatocellular carcinoma

Hsu, P. I., Chow, N-H., Lai, K. H., Yang, H. B., Chan, S-H., Lin, X-Z., Cheng, J. S., Huang, J. S., Ger, L. P., Huang, S-M., Yen, M. Y. & Yang, Y. F., 1997 Sep 3, In : Anticancer Research. 17, 4 A, p. 2803-2809 7 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Liver Diseases
Hepatocellular Carcinoma
Chronic Disease
Serum
12 Citations (Scopus)

Prognostic significance of proliferating cell nuclear antigen expression in transitional cell carcinoma of the upper urinary tract

Cheng, H-L., Chow, N-H., Tzai, T. S., Tong, Y-C., Lin, J. S. N., Chan, S-H., Yang, W-H., Chang, C. C. & Lin, Y., 1997 Sep 3, In : Anticancer Research. 17, 4 A, p. 2789-2793 5 p.

Research output: Contribution to journalArticle

Transitional Cell Carcinoma
Proliferating Cell Nuclear Antigen
Urinary Tract
Neoplasms
Survival
91 Citations (Scopus)

Significance of urinary epidermal growth factor and its receptor expression in human bladder cancer

Chow, N-H., Liu, H-S., Lee, E. I. C., Chang, C-J., Chan, S-H., Cheng, H-L., Tzai, T. S. & Lin, J. S. N., 1997 Dec 1, In : Anticancer Research. 17, 2B, p. 1293-1296 4 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Urinary Bladder Neoplasms
Epidermal Growth Factor
Urine
Neoplasms
1996
36 Citations (Scopus)

Clinical presentation and prognostic factors in sodium monofluoroacetate intoxication

Chi, C-H., Chen, K. W., Chan, S-H., Wu, M. H. & Huang, J. J., 1996 Jan 1, In : Journal of Toxicology - Clinical Toxicology. 34, 6, p. 707-712 6 p.

Research output: Contribution to journalArticle

Hypotension
Creatinine
Sodium
Survival
Mortality
29 Citations (Scopus)

Growth kinetics of colorectal adenoma-carcinoma sequence: An immunohistochemical study of proliferating cell nuclear antigen expression

Yang, H. B., Hsu, P. I., Chan, S-H., Lee, J-C., Shin, J. S. & Chow, N-H., 1996 Jan 1, In : Human Pathology. 27, 10, p. 1071-1076 6 p.

Research output: Contribution to journalArticle

Proliferating Cell Nuclear Antigen
Adenoma
Colorectal Neoplasms
Growth
Carcinoma
13 Citations (Scopus)

Implications of urinary basic fibroblast growth factor excretion in patients with urothelial carcinoma

Chow, N-H., Chang, C-J., Yeh, T-M., Chan, S-H., Tzai, T. S. & Lin, J. S. N., 1996 Jan 1, In : Clinical Science. 90, 2, p. 127-133 7 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Carcinoma
Urine
Neoplasms
Urologic Diseases
1995
18 Citations (Scopus)

Adenoma‐carcinoma sequence: A reappraisal with immunohistochemical expression of ferritin

Yang, HB. B., Hsu, PI. I., Lee, JC. C., Chan, S-H., Lin, X-Z. & Chow, N-H., 1995 Jan 1, In : Journal of Surgical Oncology. 60, 1, p. 35-40 6 p.

Research output: Contribution to journalArticle

Ferritins
Adenoma
Mucous Membrane
Neoplasms
Colorectal Neoplasms
3 Citations (Scopus)

Prognostic significance of ferritin expression in colorectal adenocarcinoma

Hsu, P. I., Chow, N-H., Lin, X-Z., Yang, H. B., Chan, S-H. & Lee, P. C., 1995 Jan 1, In : Anticancer Research. 15, 3, p. 1087-1093 7 p.

Research output: Contribution to journalArticle

Ferritins
Adenocarcinoma
Neoplasm Metastasis
Neoplasms
Stromal Cells
15 Citations (Scopus)

Significance of urinary tissue polypeptide specific antigen (TPS). Determination in patients with urothelial carcinoma

Yao, W-J., Chang, C-J., Chan, S-H., Chow, N-H., Cheng, H-L., Tzai, T. S. & Lin, S. N., 1995 Dec 1, In : Anticancer Research. 15, 6 B, p. 2819-2823 5 p.

Research output: Contribution to journalArticle

Urine
Carcinoma
Transitional Cell Carcinoma
Urologic Diseases
tissue polypeptide specific antigen
1994
63 Citations (Scopus)

Bleeding peptic ulcer - Risk factors for rebleeding and sequential changes in endoscopic findings

Hsu, P. I., Lin, X-Z., Chan, S-H., Lin, C. Y., Chang, T-T., Shin, J. S., Hsu, L. Y., Yang, C. C. & Chen, K. W., 1994 Jan 1, In : Gut. 35, 6, p. 746-749 4 p.

Research output: Contribution to journalArticle

Peptic Ulcer
Ulcer
Hemorrhage
Shock
Endoscopy
15 Citations (Scopus)

Urinary cytodiagnosis: Can it have a different prognostic implication than a diagnostic test?

Chow, N-H., Tzai, T. S., Cheng, H-L., Chan, S-H. & Lin, J. S. N., 1994 Jan 1, In : Urologia Internationalis. 53, 1, p. 18-23 6 p.

Research output: Contribution to journalArticle

Cytodiagnosis
Routine Diagnostic Tests
Cell Biology
Neoplasms
Transitional Cell Carcinoma
1993
16 Citations (Scopus)

Reappraisal of the biological role of epidermal growth factor receptor in transitional cell carcinoma

Chow, N-H., Tzai, T. S., Lin, S. N., Chan, S-H. & Tang, M-J., 1993 Jan 1, In : European Urology. 24, 1, p. 140-143 4 p.

Research output: Contribution to journalArticle

Transitional Cell Carcinoma
Epidermal Growth Factor Receptor
Neoplasms
DNA
Ploidies
1991
1 Citation (Scopus)
Polynomial Splines
Maximum Likelihood Estimate
Maximum Likelihood Estimator
Knot
Regression Model