• 347 Citations
  • 12 h-Index
19992019
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Research Output 1999 2019

  • 347 Citations
  • 12 h-Index
  • 31 Article
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Article
2019

Galectin-3 aggravates ox-LDL-induced endothelial dysfunction through LOX-1 mediated signaling pathway

Ou, H. C., Chou, W. C., Hung, C-H., Chu, P. M., Hsieh, P. L., Chan, S-H. & Tsai, K-L., 2019 Jul 1, In : Environmental Toxicology. 34, 7, p. 825-835 11 p.

Research output: Contribution to journalArticle

Lipoprotein Receptors
Galectin 3
Lipoproteins
NF-kappa B
antibody

Multimodal exercise ameliorates exercise responses and body composition in head and neck cancer patients receiving chemotherapy

Yen, C-J., Hung, C-H., Kao, C. L., Tsai, W. M., Chan, S-H., Cheng, H. C., Jheng, W. T., Lu, Y. J. & Tsai, K-L., 2019 Jan 1, In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Body Composition
Exercise
Drug Therapy
Heart Rate

Relationship between body mass index, antidiabetic agents, and midterm mortality in patients with both type 2 diabetes mellitus and acute coronary syndrome

Jong, C. B., Li, H. Y., Pan, S. L., Hsieh, M. Y., Su, F. Y., Chen, K. C., Yin, W. H., Chan, S-H., Wu, Y. W., Wang, K. Y., Chang, K. C., Hwang, J. J. & Wu, C. C., 2019 Jan 1, In : Journal of the American Heart Association. 8, 7, e011215.

Research output: Contribution to journalArticle

Open Access
Acute Coronary Syndrome
Hypoglycemic Agents
Type 2 Diabetes Mellitus
Body Mass Index
Mortality
2018
9 Citations (Scopus)

Chlorogenic Acid Protects Against oxLDL-Induced Oxidative Damage and Mitochondrial Dysfunction by Modulating SIRT1 in Endothelial Cells

Tsai, K-L., Hung, C-H., Chan, S-H., Hsieh, P. L., Ou, H. C., Cheng, Y. H. & Chu, P. M., 2018 Jun 1, In : Molecular Nutrition and Food Research. 62, 11, 1700928.

Research output: Contribution to journalArticle

Chlorogenic Acid
chlorogenic acid
endothelial cells
Endothelial Cells
AMP-Activated Protein Kinases
6 Citations (Scopus)

Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling

Chan, S-H., Hung, C-H., Shih, J. Y., Chu, P. M., Cheng, Y. H., Lin, H. C., Hsieh, P. L. & Tsai, K-L., 2018 Apr 1, In : Redox Biology. 14, p. 116-125 10 p.

Research output: Contribution to journalArticle

Sirtuin 1
Hyperhomocysteinemia
NADPH Oxidase
Endothelium
Wounds and Injuries
5 Citations (Scopus)

In-hospital implementation of evidence-based, medications is associated with improved survival, in diabetic patients with acute coronary, syndrome - Data from TSOC ACS-DM registry

Chen, K. C., Yin, W. H., Wu, C. C., Chan, S-H., Wu, Y. W., Wang, K. Y., Chang, K. C., Hwang, J. J., Voon, W. C., Hsieh, I. C., Chong, J. T., Lin, W. S., Hsu, C. N., Ueng, K. C., Hsia, C. P., Liu, J. C., Yeh, J. S., Mar, G. Y., Shih, J. Y., Kuo, J. Y. & 8 others, Tsao, H. M., Tseng, W. K., Yang, C. H., Chang, C. C., Chiang, C. E., Lei, M. H., Lin, J. F. & Shyu, K. G., 2018 May 1, In : Acta Cardiologica Sinica. 34, 3, p. 211-223 13 p.

Research output: Contribution to journalArticle

Acute Coronary Syndrome
Registries
Diabetes Mellitus
Survival
Taiwan
2017
2 Citations (Scopus)
Dissection
Perfusion
Myocardial Infarction
Aorta
Hospital Emergency Service
7 Citations (Scopus)

Oleate-induced PTX3 promotes head and neck squamous cell carcinoma metastasis through the up-regulation of vimentin

Chan, S-H., Tsai, J. P., Shen, C. J., Liao, Y. H. & Chen, B-K., 2017 Jan 1, In : Oncotarget. 8, 25, p. 41364-41378 15 p.

Research output: Contribution to journalArticle

Vimentin
Oleic Acid
Up-Regulation
Neoplasm Metastasis
Neoplasms
9 Citations (Scopus)

Oleic acid-induced ANGPTL4 enhances head and neck squamous cell carcinoma anoikis resistance and metastasis via up-regulation of fibronectin

Shen, C. J., Chan, S-H., Lee, C-T., Huang, W. C., Tsai, J. P. & Chen, B-K., 2017 Feb 1, In : Cancer Letters. 386, p. 110-122 13 p.

Research output: Contribution to journalArticle

Anoikis
Oleic Acid
Fibronectins
Up-Regulation
Neoplasm Metastasis
13 Citations (Scopus)

SIRT1 inhibition causes oxidative stress and inflammation in patients with coronary artery disease

Chan, S-H., Hung, C-H., Shih, J. Y., Chu, P. M., Cheng, Y. H., Lin, H. C. & Tsai, K-L., 2017 Oct 1, In : Redox Biology. 13, p. 301-309 9 p.

Research output: Contribution to journalArticle

Sirtuin 1
Oxidative stress
Coronary Artery Disease
Oxidative Stress
Inflammation
2 Citations (Scopus)

The efficacy and safety of using extension catheters in complex coronary interventions: A single center experience

Huang, M. S., Wu, C. I., Chang, F. H., Chang, H. Y., Lee, P-T., Chen, Z-Y., Li, W-H., Lin, C-C., Chan, S-H., Liu, P-Y. & Lee, C-H., 2017 Sep 1, In : Acta Cardiologica Sinica. 33, 5, p. 468-476 9 p.

Research output: Contribution to journalArticle

Catheters
Stents
Safety
Percutaneous Coronary Intervention
Dissection
2016
6 Citations (Scopus)
Percutaneous Coronary Intervention
Cause of Death
Quality of Health Care
Hospital Mortality
Tertiary Care Centers
4 Citations (Scopus)

Baicalein is an available anti-atherosclerotic compound through modulation of nitric oxide-related mechanism under oxLDL exposure

Chan, S-H., Hung, C-H., Shih, J. Y., Chu, P. M., Cheng, Y. H., Tsai, Y-J., Lin, H. C. & Tsai, K-L., 2016 Jan 1, In : Oncotarget. 7, 28, p. 42881-42891 11 p.

Research output: Contribution to journalArticle

Nitric Oxide
Oxidants
Caspase 3
Reactive Oxygen Species
Oxidative Stress
13 Citations (Scopus)

Baicalein protects against oxLDL-caused oxidative stress and inflammation by modulation of AMPK- alpha

Tsai, K-L., Hung, C-H., Chan, S-H., Shih, J. Y., Cheng, Y. H., Tsai, Y-J., Lin, H. C. & Chu, P. M., 2016 Jan 1, In : Oncotarget. 7, 45, p. 72458-72468 11 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Oxidative Stress
Inflammation
Endothelial Cells
Vasodilation
11 Citations (Scopus)

Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling

Hung, C-H., Chan, S-H., Chu, P. M., Lin, H. C. & Tsai, K-L., 2016 Jan 1, In : Oncotarget. 7, 10, p. 10773-10787 15 p.

Research output: Contribution to journalArticle

Metformin
AMP-Activated Protein Kinases
Human Umbilical Vein Endothelial Cells
Wounds and Injuries
Oxidative Stress
3 Citations (Scopus)

Oleic acid activates MMPs up-regulation through SIRT1/PPAR-γ inhibition: A probable linkage between obesity and coronary arterial disease

Chan, S-H., Chu, P. M., Kao, C. L., Cheng, Y. H., Hung, C-H. & Tsai, K-L., 2016 Oct 1, In : Journal of biochemistry. 160, 4, p. 217-225 9 p.

Research output: Contribution to journalArticle

Sirtuin 1
Peroxisome Proliferator-Activated Receptors
Oleic Acid
Matrix Metalloproteinases
Coronary Disease
2015
9 Citations (Scopus)
docetaxel
Protein Kinase C beta
Oxidative stress
Oxidative Stress
Modulation
13 Citations (Scopus)
Sirtuin 1
Hyperhomocysteinemia
Homocysteine
Protein Kinase C
Methionine
23 Citations (Scopus)

PTX3 gene activation in EGF-induced head and neck cancer cell metastasis

Chang, W. C., Wu, S. L., Huang, W. C., Hsu, J. Y., Chan, S-H., Wang, J-M., Tsai, J. P. & Chen, B-K., 2015 Jan 1, In : Oncotarget. 6, 10, p. 7741-7757 17 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Epidermal Growth Factor
Transcriptional Activation
Neoplasm Metastasis
Transcription Factor AP-1
43 Citations (Scopus)
Sirtuin 1
Quercetin
quercetin
AMP-activated protein kinase
Adenosine Monophosphate
2014
25 Citations (Scopus)
Taiwan
Myocardial Infarction
Guidelines
Incidence
Hydroxymethylglutaryl-CoA Reductase Inhibitors
2012
14 Citations (Scopus)
Extracorporeal Membrane Oxygenation
Oxygenation
Ventricular Heart Septal Defects
Surgery
Repair
7 Citations (Scopus)
Insulin Receptor Substrate Proteins
Viperidae
Polymorphism
Coronary Artery Disease
Genotype
14 Citations (Scopus)

Insulin receptor substrate-1 prevents autophagy-dependent cell death caused by oxidative stress in mouse NIH/3T3 cells

Chan, S-H., Kikkawa, U., Matsuzaki, H., Chen, J. H. & Chang, W. C., 2012 Jul 16, In : Journal of biomedical science. 19, 1, 64.

Research output: Contribution to journalArticle

Open Access
Insulin Receptor Substrate Proteins
NIH 3T3 Cells
Oxidative stress
Autophagy
Cell death
2006
29 Citations (Scopus)
Matrix Metalloproteinase 3
Genetic Association Studies
Adenine
Acute Coronary Syndrome
Smoking
17 Citations (Scopus)

Increasing post-event plasma thrombomodulin level associates with worse outcome in survival of acute coronary syndrome

Chan, S-H., Chen, J. H., Li, Y-H., Lin, L. J. & Tsai, L-M., 2006 Aug 10, In : International Journal of Cardiology. 111, 2, p. 280-285 6 p.

Research output: Contribution to journalArticle

Thrombomodulin
Acute Coronary Syndrome
Survival
Unstable Angina
Sudden Cardiac Death
5 Citations (Scopus)
Arteriovenous Fistula
Fistula
Jugular Veins
Neck
Heart Failure
2 Citations (Scopus)
Platelet Activating Factor
Acute Coronary Syndrome
Coronary Artery Disease
Exons
Genes
2005
19 Citations (Scopus)

Predictors of in-hospital mortality in patients with acute aortic dissection

Chan, S-H., Liu, P-Y., Lin, L. J. & Chen, J. H., 2005 Dec 7, In : International Journal of Cardiology. 105, 3, p. 267-273 7 p.

Research output: Contribution to journalArticle

Hospital Mortality
Dissection
Odds Ratio
Confidence Intervals
Tunica Intima
34 Citations (Scopus)

Secular trends in coronary heart disease mortality, hospitalization rates, and major cardiovascular risk factors in Taiwan, 1971-2001

Cheng, Y., Chen, K. J., Wang, C-J., Chan, S-H., Chang, W. C. & Chen, J. H., 2005 Apr 8, In : International Journal of Cardiology. 100, 1, p. 47-52 6 p.

Research output: Contribution to journalArticle

Taiwan
Coronary Disease
Hospitalization
Mortality
Developed Countries
1999
3 Citations (Scopus)

Pulmonary artery leiomyosarcoma

Chan, S-H., Tsai, L-M., Tsai, W-C., Li, Y-H., Chen, J. H. & Luo, C-Y., 1999 Aug 1, In : Journal of the Formosan Medical Association. 98, 8, p. 578-581 4 p.

Research output: Contribution to journalArticle

Leiomyosarcoma
Pulmonary Artery
Pulmonary Embolism
Heart Ventricles
Radiotherapy