Shun-hua Chen

Personal profile

Education

1994 PhD, Department of Microbiology and Immunology, University of South Alabama

Experience

2018/08-present Chairs of Department of Microbiology & Immunology and Parasitology, National Cheng Kung University
2009/07-present Professor, Department of Microbiology and Immunology, National Cheng Kung University
2003/08-2009/07 Associate Professor, Department of Microbiology and Immunology, National Cheng Kung University
1998/09-2003/07 Assistant Professor, Department of Microbiology and Immunology, National Cheng Kung University

Research Interests

Virology

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探討?疹病毒感染及阿滋海默症互相惡化之機制

Chen, S.

17-08-01 → 18-07-31

Project: Research project

以小鼠模式及免疫與細胞因子觀點研究腸病毒造成重症之致病機轉及最合適且新穎的療法-抑制type I IL-20 receptor cytokines降低腸病毒71型在小鼠致死率(3/3)

Chen, S.

17-01-01 → 17-12-31

Project: Research project

探討?疹病毒感染及阿滋海默症互相惡化之機制

Chen, S.

16-08-01 → 17-07-31

Project: Research project

以小鼠模式及免疫與細胞因子觀點研究腸病毒造成重症之致病機轉及最合適且新穎的療法-抑制type I IL-20 receptor cytokines降低腸病毒71型在小鼠致死率(2/3)

Chen, S.

16-01-01 → 16-12-31

Project: Research project

探討 Annexin A1 促進單純?疹病毒造成腦炎或失明的分子機制

Chen, S.

15-08-01 → 16-07-31

Project: Research project

Research Output 1992 2018

4078 Citations
35 h-Index
93 Article
2 Review article
1 Comment/debate

Flt3 ligand treatment reduces enterovirus A71 lethality in mice with enhanced B cell responses

Lin, Y. W., Wang, L. C., Lee, C. K. & Chen, S., 2018 Dec 1, In : Scientific reports. 8, 1, 12184.

Research output: Contribution to journal › Article

Enterovirus

B-Lymphocytes

Enterovirus Infections

Viral Load

Therapeutics

12 Citations (Scopus)

Herpes simplex virus 1 tegument protein VP22 abrogates cGAS/ STING-mediated antiviral innate immunity

Huang, J., You, H., Su, C., Li, Y., Chen, S. & Zheng, C., 2018 Aug 1, In : Journal of Virology. 92, 15, e00841-18.

Research output: Contribution to journal › Article

GMP synthase (glutamine-hydrolyzing)

cyclic GMP

Human herpesvirus 1

interferons

Innate Immunity

23 Citations (Scopus)

PM_2.5-induced oxidative stress increases intercellular adhesion molecule-1 expression in lung epithelial cells through the IL-6/AKT/STAT3/NF-ΚB-dependent pathway

Liu, C. W., Lee, T. L., Chen, Y. C., Liang, C. J., Wang, S. H., Lue, J. H., Tsai, J. S., Lee, S. W., Chen, S., Yang, Y. F., Chuang, T. Y. & Chen, Y. L., 2018 Jan 12, In : Particle and Fibre Toxicology. 15, 1, 4.

Research output: Contribution to journal › Article

Oxidative stress

Particulate Matter

Intercellular Adhesion Molecule-1

Interleukin-6

Oxidative Stress

Toll-like receptor 3 is involved in detection of enterovirus a71 infection and targeted by viral 2a protease

Chen, K. R., Yu, C-K., Kung, S. H., Chen, S., Chang, C-F., Ho, T. C., Lee, Y. P., Chang, H. C., Huang, L. Y., Lo, S. Y., Chang, J. C. & Ling, P., 2018 Dec 1, In : Viruses. 10, 12, 689.

Research output: Contribution to journal › Article

Toll-Like Receptor 3

Enterovirus Infections

Peptide Hydrolases

Antiviral Agents

Enterovirus

24 Citations (Scopus)

Adipose-Derived Stem Cells Protect Skin Flaps against Ischemia/Reperfusion Injury via IL-6 Expression

Pu, C. M., Liu, C. W., Liang, C. J., Yen, Y. H., Chen, S., Jiang-Shieh, Y. F., Chien, C. L., Chen, Y. C. & Chen, Y. L., 2017 Jun 1, In : Journal of Investigative Dermatology. 137, 6, p. 1353-1362 10 p.

Research output: Contribution to journal › Article

Stem cells

Reperfusion Injury

Interleukin-6

Stem Cells

Flaps