Projects per year
Personal profile
Education
- 1982 Taipei Medical College, M.D.
Research Interests
- Hepatitis
- Hepatocellular Carcinoma
- Virology
Experience
- 1990/8~1993/7 Instructor of Medicine, Medical College, National Cheng Kung University (NCKU)
- 1993/8~1996/7 Associate Professor, Medical College, National Cheng Kung University (NCKU)
- 1996/8~present Professor of Medicine, Medical College, National Cheng Kung University (NCKU)
- 1998/8~2000/7 Secretary of Medical Affairs, National Cheng Kung University Hospital (NCKUH)
- 2000/8~2002/7 Director, Department of Clinical Medicine, National Cheng Kung University Hospital (NCKUH)
- 2000/8~2004/7 Director, Institute of Molecular Medicine, Medical College, National Cheng Kung University (NCKU)
- 2000/8~2004/7 Chief, Division of Gastroenterology, National Cheng Kung University Hospital (NCKUH)
- 2003~present Director, Biotechnologic Center of Hepatology, Research and Services Headquarter of National Cheng Kung University
- 2006~present Distinguished Professor of Internal Medicine, Medical College, NCKU
- 2013/8~2017/7 Associate Director, Medical College, National Cheng Kung University Hospital (NCKUH)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Projects
- 40 Finished
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探討病患肝組織、糞便及口腔之微生物菌相及其相關因子在肝細胞癌和膽道癌中所扮演的角色並探尋術後復發之生物標的
Chang, T.-T. (PI)
21-08-01 → 22-07-31
Project: Research project
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探討病患肝組織、糞便及口腔之微生物菌相及其相關因子在肝細胞癌和膽道癌中所扮演的角色並探尋術後復發之生物標的
Chang, T.-T. (PI)
20-08-01 → 21-07-31
Project: Research project
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探討新發現的B型肝炎病毒表面抗原變異株經由DNA損傷反應導致肝癌的致病 機制及臨床抗癌藥物之應用
Chang, T.-T. (PI)
19-08-01 → 20-07-31
Project: Research project
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探討病患肝組織、糞便及口腔之微生物菌相及其相關因子在肝細胞癌和膽道癌中所扮演的角色並探尋術後復發之生物標的
Chang, T.-T. (PI)
19-08-01 → 22-07-31
Project: Research project
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探討新發現的B型肝炎病毒表面抗原變異株經由DNA損傷反應導致肝癌的致病 機制及臨床抗癌藥物之應用
Chang, T.-T. (PI)
19-08-01 → 20-07-31
Project: Research project
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Comparing immunotherapy effectiveness for unresectable hepatocellular carcinoma: infiltrative versus non-infiltrative types in real-world settings
Chiang, C. M., Huang, K. K., Lee, C. T., Hong, T. C., Wu, J. S., Wu, H. T., Chang, T. T., Liu, Y. S., Chen, W. T., Wang, C. T., Chang, C., Chen, P. J., Hsieh, M. T., Chen, C. Y., Chuang, C. H., Lee, C. C., Lin, S. H., Lin, Y. J. & Kuo, H. Y., 2025 Jan 1, In: Therapeutic Advances in Medical Oncology. 17Research output: Contribution to journal › Article › peer-review
Open Access -
Development of an NGS-Based Estimation of Integrated HBV DNA in Liver Biopsies and Detection in Liquid Biopsies
Liu, H. N., Lin, S. Y., Ramirez, R., Chen, S. E., Heimer, Z. R., Kubas, R., Shieh, F. S., Kim, E. S., Liu, Y., Lau, D. T. Y., Chang, T. T., Guo, H., Wang, Z. & Su, Y. H., 2025 Mar, In: Journal of Medical Virology. 97, 3, e70290.Research output: Contribution to journal › Article › peer-review
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HBV Recurrence Detected by HBV-Related Serum Markers and Immune Escape Mutations in Chronic Hepatitis B Patients Following Liver Transplantation
Chiang, C. M., Lin, Y. J., Liu, W. C., Chou, T. C., Tsai, C. H., Chang, T. T. & Wu, I. C., 2025 Mar, In: Journal of Medical Virology. 97, 3, e70306.Research output: Contribution to journal › Article › peer-review
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Long-Term Hepatic and Extrahepatic Outcomes of Chronic Hepatitis C Patients After Sofosbuvir-Based Treatment (LONGHEAD Study)
Huang, C. F., Heo, J., Chien, R. N., Baek, Y. H., Kao, J. H., Kim, J. H., Chang, T. T., Byun, K. S., Chen, J. J., Jeong, S. H., Hu, T. H., Kim, Y. S., Peng, C. Y., Tak, W. Y., Wang, H. Y., Yoon, S. K., Sheen, I. S., Youn-Jae Lee, Hsu, Y. C. & Yim, H. J. & 10 others, , 2025 May, In: Infectious Diseases and Therapy. 14, 5, p. 1089-1101 13 p., 100705.Research output: Contribution to journal › Article › peer-review
Open Access -
Agalactosyl IgG induces liver fibrogenesis via Fc gamma receptor 3a on human hepatic stellate cells
Ho, C. H., Chang, T. T., Lin, H. C. & Wang, S. F., 2024 Aug, In: Journal of Pathology. 263, 4-5, p. 508-519 12 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus)