• 2892 Citations
  • 26 h-Index
1993 …2020
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Research Output 1993 2019

  • 2892 Citations
  • 26 h-Index
  • 58 Article
  • 1 Comment/debate
  • 1 Review article
13 Citations (Scopus)

The antitumor agent PBT-1 directly targets HSP90 and hnRNP A2/B1 and inhibits lung adenocarcinoma growth and metastasis

Chen, C. Y., Yang, S. C., Lee, K. H., Yang, X., Wei, L. Y., Chow, L. P., Wang, T. C. V., Hong, T-M., Lin, J. C., Kuan, C. & Yang, P. C., 2014 Feb 13, In : Journal of Medicinal Chemistry. 57, 3, p. 677-685 9 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein Group A-B
HSP90 Heat-Shock Proteins
Antineoplastic Agents
Neoplasm Metastasis
Gastropoda
1 Citation (Scopus)

The dual PI3K/mTOR inhibitor BEZ235 restricts the growth of lung cancer tumors regardless of EGFR status, as a potent accompanist in combined therapeutic regimens

Wu, Y. Y., Wu, H. C., Wu, J. E., Huang, K. Y., Yang, S. C., Chen, S. X., Tsao, C. J., Hsu, K-F., Chen, Y. L. & Hong, T-M., 2019 Jul 1, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 282.

Research output: Contribution to journalArticle

Open Access
1-Phosphatidylinositol 4-Kinase
Sirolimus
Epidermal Growth Factor Receptor
Lung Neoplasms
Non-Small Cell Lung Carcinoma
18 Citations (Scopus)

The Motor Protein KIF14 Inhibits Tumor Growth and Cancer Metastasis in Lung Adenocarcinoma

Hung, P. F., Hong, T-M., Hsu, Y. C., Chen, H. Y., Chang, Y. L., Wu, C. T., Chang, G. C., Jou, Y. S., Pan, S. H. & Yang, P. C., 2013 Apr 23, In : PloS one. 8, 4, e61664.

Research output: Contribution to journalArticle

adenocarcinoma
metastasis
Tumors
lungs
Neoplasm Metastasis
61 Citations (Scopus)

The transcriptional factor YY1 upregulates the novel invasion suppressor HLJ1 expression and inhibits cancer cell invasion

Wang, C. C., Tsai, M. F., Hong, T-M., Chang, G. C., Chen, C. Y., Yang, W. M., Chen, J. J. W. & Yang, P. C., 2005 Jun 9, In : Oncogene. 24, 25, p. 4081-4093 13 p.

Research output: Contribution to journalArticle

Up-Regulation
Genetic Promoter Regions
Cadherins
Neoplasms
HSP40 Heat-Shock Proteins
19 Citations (Scopus)

Tid1-L inhibits EGFR signaling in lung adenocarcinoma by enhancing EGFR ubiquitinylation and degradation

Chen, C. Y., Jan, C. I., Lo, J. F., Yang, S. C., Chang, Y. L., Pan, S. H., Wang, W. L., Hong, T-M. & Yang, P. C., 2013 Jul 1, In : Cancer Research. 73, 13, p. 4009-4019 11 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Adenocarcinoma of lung
Lung Neoplasms
Protein Isoforms
Cell Proliferation
166 Citations (Scopus)

Transcription repressor Slug promotes carcinoma invasion and predicts outcome of patients with lung adenocarcinoma

Shih, J. Y., Tsai, M. F., Chang, T. H., Chang, Y. L., Yuan, A., Yu, C. J., Lin, S. B., Liou, G. Y., Lee, M. L., Chen, J. J. W., Hong, T-M., Yang, S. C., Su, J. L., Lee, Y. C. & Yang, P. C., 2005 Nov 15, In : Clinical Cancer Research. 11, 22, p. 8070-8078 9 p.

Research output: Contribution to journalArticle

Gastropoda
Carcinoma
Matrix Metalloproteinase 2
Neoplasms
Adenocarcinoma of lung
35 Citations (Scopus)

TROP2 is epigenetically inactivated and modulates IGF-1R signalling in lung adenocarcinoma

Lin, J. C., Wu, Y. Y., Wu, J. Y., Lin, T. C., Wu, C. T., Chang, Y. L., Jou, Y. S., Hong, T-M. & Yang, P. C., 2012 Jun 1, In : EMBO Molecular Medicine. 4, 6, p. 472-485 14 p.

Research output: Contribution to journalArticle

Loss of Heterozygosity
decitabine
Lung Neoplasms
Cell Line
Catenins
217 Citations (Scopus)

Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: Its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer

Chen, J. J. W., Yao, P. L., Yuan, A., Hong, T-M., Shun, C. T., Kuo, M. L., Lee, Y. C. & Yang, P. C., 2003 Feb 1, In : Clinical Cancer Research. 9, 2, p. 729-737 9 p.

Research output: Contribution to journalArticle

Interleukin-8
Non-Small Cell Lung Carcinoma
Up-Regulation
Macrophages
Survival
18 Citations (Scopus)

α-catulin drives metastasis by activating ILK and driving an αvβ3 integrin signaling axis

Liang, C. H., Chiu, S. Y., Hsu, I. L., Wu, Y. Y., Tsai, Y. T., Ke, J. Y., Pan, S. H., Hsu, Y. C., Li, K. C., Yang, P. C., Chen, Y-L. & Hong, T-M., 2013 Jan 1, In : Cancer Research. 73, 1, p. 428-438 11 p.

Research output: Contribution to journalArticle

Integrins
Neoplasm Metastasis
Non-Small Cell Lung Carcinoma
Cell Movement
Cell Aging
13 Citations (Scopus)

α-Catulin knockdown induces senescence in cancer cells

Fan, L. C., Chiang, W. F., Liang, C. H., Tsai, Y. T., Wang, D-Y., Chen, K-C., Hong, T-M. & Chen, Y-L., 2011 Jun 9, In : Oncogene. 30, 23, p. 2610-2621 12 p.

Research output: Contribution to journalArticle

Cell Aging
Neoplasms
DNA Damage
DNA Repair
Down-Regulation