• 3183 Citations
  • 26 h-Index
1988 …2018
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Personal profile

Education

  • 1990 PhD, Department of Biochemistry, University of Virginia

Experience

  • 1994~2003, Associate professor, Department of Pharmacology, College of Medicine, National Cheng Kung University
  • 2003~present Professor, Department of Pharmacology, College of Medicine, National Cheng Kung Universit
  • 2008~2014, Chairperson, Department of Pharmacology, College of Medicine, National Cheng Kung University

Research Interests

  • Oncogene

Fingerprint Dive into the research topics where Tzeng-Horng Leu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Focal Adhesion Protein-Tyrosine Kinases Medicine & Life Sciences
Macrophages Chemical Compounds
Tetrahydrofolate Dehydrogenase Medicine & Life Sciences
Phosphorylation Chemical Compounds
Cricetulus Medicine & Life Sciences
Lipopolysaccharides Medicine & Life Sciences
Chemical activation Chemical Compounds
Toll-Like Receptors Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1995 2018

研究Eps8-IRSp53交互作用參與細胞癌化之機制探討

Leu, T.

17-08-0118-07-31

Project: Research project

Eps8-IRSp53交互作用參與細胞癌化之機制探討

Leu, T.

14-08-0115-07-31

Project: Research project

以Eps8作為大腸直腸癌治療的標靶(3/3)

Leu, T.

13-05-0114-04-30

Project: Research project

以Eps8作為大腸直腸癌治療的標靶(2/3)

Leu, T.

12-05-0113-04-30

Project: Research project

以Eps8作為大腸直腸癌治療的標靶(1/3)

Leu, T.

11-05-0112-04-30

Project: Research project

Research Output 1988 2017

  • 3183 Citations
  • 26 h-Index
  • 43 Article
  • 4 Review article
  • 1 Short survey
6 Citations (Scopus)

Vibrio vulnificus MARTX cytotoxin causes inactivation of phagocytosis-related signaling molecules in macrophages

Chen, C. L., Chien, S. C., Leu, T-H., Harn, H. I. C., Tang, M-J. & Hor, L. I., 2017 Aug 19, In : Journal of biomedical science. 24, 1, 58.

Research output: Contribution to journalArticle

Vibrio vulnificus
Macrophages
Cytotoxins
Phagocytosis
Focal Adhesion Kinase 2
11 Citations (Scopus)

Src is required for migration, phagocytosis, and interferon beta production in Toll-like receptor-engaged macrophages

Maa, M. C. & Leu, T-H., 2016 Sep 1, In : BioMedicine (Netherlands). 6, 3, p. 5-9 5 p., e65.

Research output: Contribution to journalReview article

Macrophages
Toll-Like Receptors
Interferon-beta
Phagocytosis
Nitric Oxide Synthase Type II
13 Citations (Scopus)

Berberine reduces Toll-like receptor-mediated macrophage migration by suppression of Src enhancement

Cheng, W. E., Ying Chang, M., Wei, J. Y., Chen, Y. J., Maa, M. C. & Leu, T-H., 2015 Jun 15, In : European Journal of Pharmacology. 757, p. 1-10 10 p.

Research output: Contribution to journalArticle

Berberine
Toll-Like Receptors
Macrophages
Lipopolysaccharides
S-Nitroso-N-Acetylpenicillamine
16 Citations (Scopus)

Lipopolysaccharide-promoted proliferation of Caco-2 cells is mediated by c-Src induction and ERK activation

Lin, T. Y., Fan, C. W., Maa, M. C. & Leu, T-H., 2015 Mar 1, In : BioMedicine (Netherlands). 5, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

Caco-2 Cells
Lipopolysaccharides
Chemical activation
Colon
Growth
5 Citations (Scopus)

The iNOS/Src/FAK axis contributes to lithium chloride-mediated macrophage migration

Chen, H. C., Chien, W. C., Chang, M. Y., Hsieh, M. Y., Lai, M-D., Maa, M. C. & Leu, T-H., 2015 May 1, In : Nitric Oxide - Biology and Chemistry. 47, p. 58-64 7 p.

Research output: Contribution to journalArticle

Lithium Chloride
Macrophages
kenpaullone
Peritoneal Macrophages
Phosphorylation

Thesis

Eps8 在骨重塑中所扮演的角色

Author: 昌達, 李., 2015 Aug 6

Supervisor: Leu, T. (Supervisor)

Student thesis: Master's Thesis

Functional study of v-HRas ubiquitination

Author: 國允, 高., 2015 Aug 5

Supervisor: Leu, T. (Supervisor)

Student thesis: Master's Thesis

Study the role of Eps8 in the interaction between cancer cells and macrophages

Author: 薇螢, 曾., 2017 Aug 1

Supervisor: Leu, T. (Supervisor)

Student thesis: Master's Thesis

Study the role of IRSp53 isoforms in colorectal cancer

Author: 韻如, 彭., 2016 Aug 4

Supervisor: Leu, T. (Supervisor)

Student thesis: Master's Thesis

The role of Eps8/Src axis in macrophage-mediated innate immunity

Author: 銘育, 謝., 2015 Jul 8

Supervisor: Leu, T. (Supervisor)

Student thesis: Doctoral Thesis