If you made any changes in Pure these will be visible here soon.

Research Output

  • 1282 Citations
  • 21 h-Index
  • 55 Article
  • 18 Patent
  • 6 Conference contribution
  • 1 Review article
Filter
Article
2020

Cloning and characterisation of type I interferon receptor 1 in orange-spotted grouper (Epinephelus coioides) for response to nodavirus infection

Tang, Z. Z., Wang, T. Y., Chen, Y. M. & Chen, T. Y., 2020 Jun, In : Fish and Shellfish Immunology. 101, p. 302-311 10 p.

Research output: Contribution to journalArticle

2019

Impact of Tilapia hepcidin 2-3 dietary supplementation on the gut microbiota profile and immunomodulation in the grouper (Epinephelus lanceolatus)

Ting, C. H., Pan, C. Y., Chen, Y. C., Lin, Y. C., Chen, T. Y., Rajanbabu, V. & Chen, J. Y., 2019 Dec 1, In : Scientific reports. 9, 1, 19047.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Novel subunit vaccine with linear array epitope protect giant grouper against nervous necrosis virus infection

Lin, C. F., Jiang, H. K., Chen, N. C., Wang, T. Y. & Chen, T. Y., 2018 Mar 1, In : Fish and Shellfish Immunology. 74, p. 551-558 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Viral infection upregulates myostatin promoter activity in orange-spotted grouper (Epinephelus coioides)

Chen, Y. T., Lin, C. F., Chen, Y. M., Lo, C. E., Chen, W. E. & Chen, T. Y., 2017 Oct, In : PloS one. 12, 10, e0186506.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2016

A member of the immunoglobulin superfamily, orange-spotted grouper novel immune gene EcVig, is induced by immune stimulants and type I interferon

Yeh, Y. C., Wang, T. Y., Chou, H. Y., Lin, H. Y., Chen, T. Y., Aoki, T. & Wang, H. C., 2016 Nov 1, In : Fish and Shellfish Immunology. 58, p. 415-422 8 p.

Research output: Contribution to journalArticle

Analysis of interferon gamma protein expression in zebrafish (Danio rerio)

Yoon, S., Alnabulsi, A., Wang, T. Y., Lee, P. T., Chen, T. Y., Bird, S., Zou, J. & Secombes, C. J., 2016 Oct 1, In : Fish and Shellfish Immunology. 57, p. 79-86 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
4 Citations (Scopus)
2015

A microfluidic system integrated with buried optical fibers for detection of Phalaenopsis orchid pathogens

Lin, C. L., Chang, W. H., Wang, C. H., Lee, C. H., Chen, T. Y., Jan, F. J. & Lee, G. B., 2015 Jan 15, In : Biosensors and Bioelectronics. 63, p. 572-579 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Cordyceps s.L. (ascomycetes) species used as medicinal mushrooms are closely related with higher ability to produce cordycepin

Kuo, H. C., Huang, I. C. & Chen, T. Y., 2015 Jan 1, In : International Journal of Medicinal Mushrooms. 17, 11, p. 1077-1085 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection

Chen, N. C., Yoshimura, M., Guan, H. H., Wang, T. Y., Misumi, Y., Lin, C. C., Chuankhayan, P., Nakagawa, A., Chan, S. I., Tsukihara, T., Chen, T. Y. & Chen, C. J., 2015 Jan 1, In : PLoS pathogens. 11, 10, e1005203.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Genome sequence of Trichoderma virens FT-333 from tropical marine climate

Kuo, H. C., Wang, T. Y., Chen, P. P., Chen, R. S. & Chen, T. Y., 2015 Jan 1, In : FEMS Microbiology Letters. 362, 7, fnv036.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Molecular cloning and characterization of orange-spotted grouper (Epinephelus coioides) CXC chemokine ligand 12

Wu, C. S., Wang, T. Y., Liu, C. F., Lin, H. P., Chen, Y. M. & Chen, T. Y., 2015 Dec 1, In : Fish and Shellfish Immunology. 47, 2, p. 996-1005 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Rapid and amplification-free detection of fish pathogens by utilizing a molecular beacon-based microfluidic system

Su, Y. C., Wang, C. H., Chang, W. H., Chen, T. Y. & Lee, G. B., 2015 Jan 15, In : Biosensors and Bioelectronics. 63, p. 196-203 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Regulatory factors controlling muscle mass: Competition between innate immune function and anabolic signals in regulation of atrogin-1 in Atlantic salmon

Heidari, Z., Bickerdike, R., Tinsley, J., Zou, J., Wang, T. Y., Chen, T. Y. & Martin, S. A. M., 2015 Oct 1, In : Molecular Immunology. 67, 2, p. 341-349 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2014

Development of pedigree classification using microsatellite and mitochondrial markers for giant grouper broodstock (Epinephelus lanceolatus) management in Taiwan

Kuo, H. C., Hsu, H. A., Chua, C. S., Wang, T. Y., Chen, Y. M. & Chen, T. Y., 2014 May, In : Marine Drugs. 12, 5, p. 2397-2407 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

EcVig, a novel grouper immune-gene associated with antiviral activity against NNV infection

Yeh, Y. C., Hsu, Y. J., Chen, Y. M., Lin, H. Y., Yang, H. L., Chen, T. Y. & Wang, H. C., 2014 Mar 1, In : Developmental and Comparative Immunology. 43, 1, p. 68-75 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Functional analysis of an orange-spotted grouper (Epinephelus coioides) interferon gene and characterisation of its expression in response to nodavirus infection

Chen, Y. M., Kuo, C. E., Chen, G. R., Kao, Y. T., Zou, J., Secombes, C. J. & Chen, T-Y., 2014 Jan 1, In : Developmental and Comparative Immunology. 46, 2, p. 117-128 12 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Salmonids have an extraordinary complex type I IFN system: Characterization of the IFN locus in rainbow trout oncorhynchus mykiss reveals two novel IFN subgroups

Zou, J., Gorgoglione, B., Taylor, N. G. H., Summathed, T., Lee, P. T., Panigrahi, A., Genet, C., Chen, Y. M., Chen, T. Y., Ul Hassan, M., Mughal, S. M., Boudinot, P. & Secombes, C. J., 2014 Sep 1, In : Journal of Immunology. 193, 5, p. 2273-2286 14 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
2013

Detection of viruses directly from the fresh leaves of a Phalaenopsis orchid using a microfluidic system

Chang, W. H., Yang, S. Y., Lin, C. L., Wang, C. H., Li, P. C., Chen, T. Y., Jan, F. J. & Lee, G. B., 2013 Nov 1, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 9, 8, p. 1274-1282 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Enhancing microalgal oil/lipid production from Chlorella sorokiniana CY1 using deep-sea water supplemented cultivation medium

Chen, C. Y., Chang, J. S., Chang, H. Y., Chen, T. Y., Wu, J. H. & Lee, W. L., 2013 Aug 5, In : Biochemical Engineering Journal. 77, p. 74-81 8 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Rapid isolation and detection of aquaculture pathogens in an integrated microfluidic system using loop-mediated isothermal amplification

Chang, W. H., Yang, S. Y., Wang, C. H., Tsai, M. A., Wang, P. C., Chen, T-Y., Chen, S. C. & Lee, G. B., 2013 Apr 1, In : Sensors and Actuators, B: Chemical. 180, p. 96-106 11 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
2012

An automated microfluidic chip system for detection of piscine nodavirus and characterization of its potential carrier in grouper farms

Kuo, H. C., Wang, T. Y., Hsu, H. H., Lee, S. H., Chen, Y. M., Tsai, T. J., Ou, M. C., Ku, H. T., Lee, G. B. & Chen, T. Y., 2012 Aug 9, In : PloS one. 7, 8, e42203.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Grouper (Epinephelus coioides) CXCR4 is expressed in response to pathogens infection and early stage of development

Lin, C. Y., Chen, Y. M., Hsu, H. H., Shiu, C. T., Kuo, H. C. & Chen, T-Y., 2012 Jan 1, In : Developmental and Comparative Immunology. 36, 1, p. 112-120 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Identification and characterization of DSCAM isoforms isolated from orange-spotted grouper Epinephelus coioides

Yeh, Y. C., Lee, C. W., Pan, Y. W., Hsu, Y. J., Hung, H. Y., Chen, Y. M., Lin, H. Y., Chen, T. Y., Yang, H. L. & Wang, H. C., 2012 Sep 1, In : Developmental and Comparative Immunology. 38, 1, p. 148-159 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Nervous necrosis virus replicates following the embryo development and dual infection with iridovirus at juvenile stage in grouper

Kuo, H. C., Wang, T. Y., Hsu, H. H., Chen, P. P., Lee, S. H., Chen, Y. M., Tsai, T. J., Wang, C. K., Ku, H. T., Lee, G. B. & Chen, T. Y., 2012 Apr 26, In : PloS one. 7, 4, e36183.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2011

A gene delivery system based on the N-terminal domain of human topoisomerase I

Chen, Y. A., Kuo, H. C., Chen, Y. M., Huang, S. Y., Liu, Y. R., Lin, S. C., Yang, H. L. & Chen, T. Y., 2011 Jun 1, In : Biomaterials. 32, 17, p. 4174-4184 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

An integrated microfluidic loop-mediated-isothermal-amplification system for rapid sample pre-treatment and detection of viruses

Wang, C. H., Lien, K. Y., Wang, T. Y., Chen, T. Y. & Lee, G. B., 2011 Jan 15, In : Biosensors and Bioelectronics. 26, 5, p. 2045-2052 8 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

An oral nervous necrosis virus vaccine using Vibrio anguillarum as an expression host provides early protection

Chen, Y-M., Shih, C. H., Liu, H. C., Wu, C. L., Lin, C. C., Wang, H-C., Chen, T-Y., Yang, H. L. & Lin, J. H. Y., 2011 Nov 16, In : Aquaculture. 321, 1-2, p. 26-33 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Cloning of crystallin from orange-spotted grouper and characterization of its activity as potential protective agent

Chen, Y. M., Kuo, C. E., Lin, C. M., Shiea, P. S. & Chen, T-Y., 2011 Jan 1, In : Results in Immunology. 1, 1, p. 60-69 10 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Identification of antigens for the development of a subunit vaccine against Photobacterium damselae ssp. piscicida

Ho, L. P., Han-You Lin, J., Liu, H. C., Chen, H. E., Chen, T-Y. & Yang, H. L., 2011 Jan 1, In : Fish and Shellfish Immunology. 30, 1, p. 412-419 8 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Molecular cloning and functional analysis of an orange-spotted grouper (Epinephelus coioides) secreted protein acidic and rich in cysteine (SPARC) and characterization of its expression response to nodavirus

Chen, Y. M., Kuo, C. E., Huang, Y. L., Shie, P. S., Liao, J. J., Yang, Y. C. & Chen, T. Y., 2011 Aug, In : Fish and Shellfish Immunology. 31, 2, p. 232-242 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Real-time quantitative PCR assay for monitoring of nervous necrosis virus infection in grouper aquaculture

Kuo, H. C., Wang, T. Y., Chen, P. P., Chen, Y. M., Chuang, H. C. & Chen, T. Y., 2011 Mar 1, In : Journal of Clinical Microbiology. 49, 3, p. 1090-1096 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

The expression of two novel orange-spotted grouper (Epinephelus coioides) TNF genes in peripheral blood leukocytes, various organs, and fish larvae

Lam, F. W. S., Wu, S. Y., Lin, S. J., Lin, C. C., Chen, Y. M., Wang, H. C., Chen, T. Y., Lin, H. T. & Lin, J. H. Y., 2011 Feb, In : Fish and Shellfish Immunology. 30, 2, p. 618-629 12 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)
2010

Cloning of an orange-spotted grouper Epinephelus coioides heat shock protein 90AB (HSP90AB) and characterization of its expression in response to nodavirus

Chen, Y. M., Kuo, C. E., Wang, T. Y., Shie, P. S., Wang, W. C., Huang, S. L., Tsai, T. J., Chen, P. P., Chen, J. C. & Chen, T-Y., 2010 Jan 1, In : Fish and Shellfish Immunology. 28, 5-6, p. 895-904 10 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
98 Citations (Scopus)
2009

A microfluidic-based system using reverse transcription polymerase chain reactions for rapid detection of aquaculture diseases

Lien, K. Y., Lee, S. H., Tsai, T. J., Chen, T. Y. & Lee, G. B., 2009 Dec 1, In : Microfluidics and Nanofluidics. 7, 6, p. 795-806 12 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2008

A comparison of the expression of immunity-related rag 1 and ikaros genes with histogenesis of the thymus in Epinephelus malabaricus (Bloch & Schneider)

Lin, J. H. Y., Lin, H. T., Lopez, C., Chen, T. Y., Chen, M. S. & Yang, H. L., 2008 Feb 1, In : Aquaculture Research. 39, 3, p. 252-262 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Establishment and application of PCR-SSCP profile for molecular typing of Cordyceps fungi

Kuo, H. C., Su, Y. L., Yang, H. L. & Chen, T-Y., 2008 Oct 1, In : Food Biotechnology. 22, 4, p. 311-325 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Grouper Mx confers resistance to nodavirus and interacts with coat protein

Chen, Y. M., Su, Y. L., Shie, P. S., Huang, S. L., Yang, H. L. & Chen, T. Y., 2008 Jan 1, In : Developmental and Comparative Immunology. 32, 7, p. 825-836 12 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)
2007
14 Citations (Scopus)

Myostatin gene organization and nodavirus-influenced expression in orange-spotted grouper (Epinephelus coioides)

Chen, Y. M., Wei, C. Y., Chien, C. H., Chang, H. W., Huang, S. I., Yang, H. L. & Chen, T. Y., 2007 Sep, In : Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics. 2, 3, p. 215-227 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2006

Cloning of an orange-spotted grouper (Epinephelus coioides) Mx cDNA and characterisation of its expression in response to nodavirus

Chen, Y. M., Su, Y. L., Lin, J. H. Y., Yang, H. L. & Chen, T. Y., 2006 Jan, In : Fish and Shellfish Immunology. 20, 1, p. 58-71 14 p.

Research output: Contribution to journalArticle

Differentiation of Cordyceps sinensis by a PCR-single-stranded conformation polymorphism-based method and characterization of the fermented products in Taiwan

Kuo, H. C., Su, Y. L., Yang, H. L., Huang, I. C. & Chen, T. Y., 2006 Aug 1, In : Food Biotechnology. 20, 2, p. 161-170 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST

Lu, T. J., Lai, W. Y., Huang, C. Y. F., Hsieh, W. J., Yu, J. S., Hsieh, Y. J., Chang, W. T., Leu, T. H., Chang, W. C., Chuang, W. J., Tang, M. J., Chen, T. Y., Lu, T. L. & Lai, M. D., 2006 Dec 15, In : Journal of Biological Chemistry. 281, 50, p. 38405-38417 13 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Vaccination with three inactivated pathogens of cobia (Rachycentron canadum) stimulates protective immunity

Lin, J. H. Y., Chen, T. Y., Chen, M. S., Chen, H. E., Chou, R. L., Chen, T. I., Su, M. S. & Yang, H. L., 2006 May 31, In : Aquaculture. 255, 1-4, p. 125-132 8 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)
2005

Identification of Chinese medicinal fungus Cordyceps sinensis by PCR-single-stranded conformation polymorphism and phylogenetic relationship

Kou, H. C., Yong-Lin, S. U., Yang, H. L. & Chen, T. Y., 2005 May 18, In : Journal of Agricultural and Food Chemistry. 53, 10, p. 3963-3968 6 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening

Wu, J. C., Chen, T. Y., Yu, C. T. R., Tsai, S. J., Hsu, J. M., Tang, M. J., Chou, C. K., Lin, W. J., Yuan, C. J. & Huang, C. Y. F., 2005 Mar 11, In : Journal of Biological Chemistry. 280, 10, p. 9013-9022 10 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

Isovitexin suppresses lipopolysaccharide-mediated inducible nitric oxide synthase through inhibition of NF-kappa B in mouse macrophages

Lin, C. M., Huang, S. T., Liang, Y. C., Lin, M. S., Shih, C. M., Chang, Y. C., Chen, T. Y. & Chen, C. T., 2005 Aug 1, In : Planta Medica. 71, 8, p. 748-753 6 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2003

Isodiospyrin as a novel human DNA topoisomerase I inhibitor

Ting, C. Y., Hsu, C. T., Hsu, H. T., Su, J. S., Chen, T. Y., Tarn, W. Y., Kuo, Y. H., Whang-Peng, J., Liu, L. F. & Hwang, J., 2003 Nov 15, In : Biochemical Pharmacology. 66, 10, p. 1981-1991 11 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2001

Characterization of drug resistance to VM-26 in A2780 ovarian carcinoma cells

Lin, C. M., Chen, T. Y., Wang, L. F., Hui, C. F. & Hwang, J., 2001 Jan 1, In : Zoological Studies. 40, 1, p. 71-78 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)