• 255 Citations
  • 8 h-Index
19932017

Research output per year

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Personal profile

Education

  • 1992 PhD, College of Pharmacy, University of Kentucky

Experience

  • 1993-1994 Lecturer, Department of Biochemitry, The Chinese University of Hong Kong
  • 1994~2003, Associate professor, Department of Pharmacology, College of Medicine, National Cheng Kung University

Research Interests

  • Leukemia drug therapy and resistance

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Projects

Research Output

  • 255 Citations
  • 8 h-Index
  • 28 Article
  • 1 Review article

Cyclic AMP (cAMP) confers drug resistance against DNA damaging agents via PKAIA in CML cells

Xiao, L. Y. & Kan, W. M., 2017 Jan 1, In : European Journal of Pharmacology. 794, p. 201-208 8 p.

Research output: Contribution to journalArticle

  • 5 Citations (Scopus)

    p53 modulates the effect of ribosomal protein S6 kinase1 (S6K1) on cisplatin toxicity in chronic myeloid leukemia cells

    Xiao, L. Y. & Kan, W-M., 2017 May 1, In : Pharmacological Research. 119, p. 443-462 20 p.

    Research output: Contribution to journalArticle

  • 2 Citations (Scopus)

    Poly ADP-ribose polymerase inhibition suppresses cisplatin toxicity in chronic myeloid leukemia cells

    Xiao, L. Y. & Kan, W. M., 2017 Jan 1, In : Anti-Cancer Drugs. 28, 3, p. 316-321 6 p.

    Research output: Contribution to journalArticle

  • 3 Citations (Scopus)

    Astrocytic CCAAT/Enhancer-Binding Protein Delta Contributes to Glial Scar Formation and Impairs Functional Recovery After Spinal Cord Injury

    Wang, S. M., Hsu, J. Y. C., Ko, C. Y., Chiu, N. E., Kan, W. M., Lai, M. D. & Wang, J. M., 2016 Nov 1, In : Molecular Neurobiology. 53, 9, p. 5912-5927 16 p.

    Research output: Contribution to journalArticle

  • 7 Citations (Scopus)
  • 3 Citations (Scopus)

    Thesis

    The role of ribosomal protein S6 kinase 1(S6K1) on cisplatin resistance in chronic myeloid leukemia (CML)

    Author: 綾儀, 蕭., 2017 May 19

    Supervisor: Kan, W. (Supervisor)

    Student thesis: Doctoral Thesis

    The role of superoxide dismutase 1 in myeloid leukemia

    Author: 玉霖, 陳., 2016 Jan 7

    Supervisor: Kan, W. (Supervisor)

    Student thesis: Doctoral Thesis

    探討cAMP和ROS對於PMA誘導人類血癌細胞模型的細胞分化為巨核細胞之影響研究

    Author: 嘉熙, 張., 2015 Aug 10

    Supervisor: Kan, W. (Supervisor)

    Student thesis: Master's Thesis

    探討cAMP次級傳遞因子對於PMA刺激人類血癌細胞株HEL細胞轉移之影響

    Author: 瑋珊, 張., 2015 May 21

    Supervisor: Kan, W. (Supervisor)

    Student thesis: Master's Thesis

    探討S6K1抑制劑對HEL細胞的影響

    Author: 翊亭, 劉., 2014 Jan 13

    Supervisor: Kan, W. (Supervisor)

    Student thesis: Master's Thesis