• 966 Citations
  • 19 h-Index
20102019

Research output per year

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Research Output

2019

Polysaccharides obtained from mycelia of cordyceps militaris attenuated doxorubicin-induced cytotoxic effects in chemotherapy

Lin, R. K., Choong, C. Y., Hsu, W. H., Tai, C. J. & Tai, C. J., 2019 Jun, In : African Health Sciences. 19, 2, p. 2156-2163 8 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Impact of pathogenic microbes and healthy microbiota by Lactobacillus-derived extracellular vesicles

Lee, B-H., Hsu, W-H. & Shen, T-L., 2018, ISEV 2018 annual Meeting (International Society for Extracellular Vesicles). Barcelona, Spain

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lactobacillus plantarum-derived extracellular vesicles improved the quality and safety of tuna meat

Hsu, W-H., Chen, K-C. & Shen, T-L., 2018, ISEV 2018 annual Meeting (International Society for Extracellular Vesicles). Barcelona, Spain

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optimal conditions for cordycepin production in surface liquid-cultured Cordyceps militaris treated with porcine liver extracts for suppression of oral cancer

Lin, L. T., Lai, Y. J., Wu, S. C., Hsu, W. H. & Tai, C. J., 2018 Jan, In : Journal of Food and Drug Analysis. 26, 1, p. 135-144 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The neuronal protection of a zinc-binding protein isolated from oyster

Hsu, W. H., Lin, Y. C., Chen, B. R., Wu, S. C. & Lee, B. H., 2018 Apr, In : Food and Chemical Toxicology. 114, p. 61-68 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Antimetastatic effects of cordycepin mediated by the inhibition of mitochondrial activity and estrogen-related receptor a in human ovarian carcinoma cells

Wang, C. W., Hsu, W. H. & Tai, C. J., 2017 Jan 1, In : Oncotarget. 8, 2, p. 3049-3058 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Dual degradation signals destruct GLI1: AMPK inhibits GLI1 through β-TrCP-mediated proteasome degradation

Zhang, R., Huang, S. Y., Li, K. K. W., Li, Y. H., Hsu, W. H., Zhang, G. J., Chang, C. J. & Yang, J. Y., 2017 Jan 1, In : Oncotarget. 8, 30, p. 49869-49881 13 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
5 Citations (Scopus)
2016

In vitro and in vivo anticancer activity of pardaxin against proliferation and growth of oral squamous cell carcinoma

Han, Y., Cui, Z., Li, Y. H., Hsu, W. H. & Lee, B. H., 2016 Jan, In : Marine Drugs. 14, 1, 2.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Miracle fruit (Synsepalum dulcificum) exhibits as a novel anti-hyperuricaemia agent

Shi, Y. C., Lin, K. S., Jhai, Y. F., Lee, B. H., Han, Y., Cui, Z., Hsu, W. H. & Wu, S. C., 2016 Feb, In : Molecules. 21, 2, 140.

Research output: Contribution to journalArticle

12 Citations (Scopus)

一種含有水晶冰花萃取物之組合物可用於改善阿茲海默症或糖尿病造成記憶損傷症狀(TW)

Translated title of the contribution: 一種含有水晶冰花萃取物之組合物可用於改善阿茲海默症或糖尿病造成記憶損傷症狀(TW)Hsu, W-H., 2016 May 11, Patent No. I532489

Research output: Patent

2015

Leptin-induced mitochondrial fusion mediates hepatic lipid accumulation

Hsu, W. H., Lee, B. H. & Pan, T. M., 2015 Dec 1, In : International Journal of Obesity. 39, 12, p. 1750-1756 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Monascus secondary metabolites monascin and ankaflavin inhibit activation of RBL-2H3 Cells

Chang, Y. Y., Hsu, W-H. & Pan, T. M., 2015 Jan 14, In : Journal of Agricultural and Food Chemistry. 63, 1, p. 192-199 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2014

A novel PPARgamma agonist monascin's potential application in diabetes prevention

Hsu, W-H. & Pan, T. M., 2014 Jan 1, In : Food and Function. 5, 7, p. 1334-1340 7 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)

Monascin and ankaflavin act as natural AMPK activators with PPARα agonist activity to down-regulate nonalcoholic steatohepatitis in high-fat diet-fed C57BL/6 mice

Hsu, W-H., Chen, T. H., Lee, B. H., Hsu, Y. W. & Pan, T. M., 2014 Jan 1, In : Food and Chemical Toxicology. 64, p. 94-103 10 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)
19 Citations (Scopus)

Monascus-Fermented Products

Pan, T. M. & Hsu, W. H., 2014 Apr 2, Encyclopedia of Food Microbiology: Second Edition. Elsevier Inc., p. 815-825 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Proteomic insight into the effect of ethanol on citrinin biosynthesis pathway in Monascus purpureus NTU 568

Tan, Y. Y., Hsu, W. H., Shih, T. W., Lin, C. H. & Pan, T. M., 2014 Oct, In : Food Research International. 64, p. 733-742 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Treatment of metabolic syndrome with ankaflavin, a secondary metabolite isolated from the edible fungus Monascus spp.

Hsu, W-H. & Pan, T. M., 2014 Jan 1, In : Applied Microbiology and Biotechnology. 98, 11, p. 4853-4863 11 p.

Research output: Contribution to journalShort survey

11 Citations (Scopus)
2013

Ankaflavin regulates adipocyte function and attenuates hyperglycemia caused by high-fat diet via PPAR-γ activation

Hsu, W. H., Liao, T. H., Lee, B. H., Hsu, Y. W. & Pan, T. M., 2013 Jan 1, In : Journal of Functional Foods. 5, 1, p. 124-132 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

A novel natural Nrf2 activator with PPARγ-agonist (monascin) attenuates the toxicity of methylglyoxal and hyperglycemia

Hsu, W-H., Lee, B. H., Chang, Y. Y., Hsu, Y. W. & Pan, T. M., 2013 Nov 1, In : Toxicology and Applied Pharmacology. 272, 3, p. 842-851 10 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
25 Citations (Scopus)

Dimerumic acid protects pancreas damage and elevates insulin production in methylglyoxal-treated pancreatic RINm5F cells

Lee, B. H., Hsu, W. H., Hsu, Y. W. & Pan, T. M., 2013 Apr 1, In : Journal of Functional Foods. 5, 2, p. 642-650 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Effect of pigeon pea (Cajanus cajan L.) on high-fat diet-induced hypercholesterolemia in hamsters

Dai, F. J., Hsu, W. H., Huang, J. J. & Wu, S. C., 2013 Mar 1, In : Food and Chemical Toxicology. 53, p. 384-391 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Effects of monascin on anti-inflammation mediated by Nrf2 activation in advanced glycation end product-treated THP-1 monocytes and methylglyoxal-treated wistar rats

Lee, B. H., Hsu, W-H., Huang, T., Chang, Y. Y., Hsu, Y. W. & Pan, T. M., 2013 Feb 13, In : Journal of Agricultural and Food Chemistry. 61, 6, p. 1288-1298 11 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Graptopetalum paraguayense and resveratrol ameliorates carboxymethyllysine (CML)-induced pancreas dysfunction and hyperglycemia

Lee, B. H., Lee, C. C., Cheng, Y. H., Chang, W. C., Hsu, W. H. & Wu, S. C., 2013 Dec, In : Food and Chemical Toxicology. 62, p. 492-498 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Inhibition of Th2 cytokine production in T cells by monascin via PPAR-γ activation

Hsu, W. H., Lee, B. H., Hsu, Y. W. & Pan, T. M., 2013 Aug 28, In : Journal of Agricultural and Food Chemistry. 61, 34, p. 8126-8133 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Monacolin K and monascin attenuated pancreas impairment and hyperglycemia induced by advanced glycation endproducts in BALB/c mice

Hsu, W-H., Lu, S. S., Lee, B. H., Hsu, Y. W. & Pan, T. M., 2013 Dec 1, In : Food and Function. 4, 12, p. 1742-1750 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
15 Citations (Scopus)

Monascin improves diabetes and dyslipidemia by regulating PPARγ and inhibiting lipogenesis in fructose-rich diet-induced C57BL/6 mice

Lee, B. H., Hsu, W. H., Huang, T., Chang, Y. Y., Hsu, Y. W. & Pan, T. M., 2013 Jun, In : Food and Function. 4, 6, p. 950-959 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
19 Citations (Scopus)
13 Citations (Scopus)

The improvements of ankaflavin isolated from Monascus-fermented products on dyslipidemia in high-fat diet-induced hasmster

Hsu, W. H., Huang, Y. C., Lee, B. H., Hsu, Y. W. & Pan, T. M., 2013 Jan 1, In : Journal of Functional Foods. 5, 1, p. 434-443 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2012

Ankaflavin: A natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo

Lee, B. H., Hsu, W. H., Chang, Y. Y., Kuo, H. F., Hsu, Y. W. & Pan, T. M., 2012 Dec 1, In : Free Radical Biology and Medicine. 53, 11, p. 2008-2016 9 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Ankaflavin, a novel Nrf-2 activator for attenuating allergic airway inflammation

Hsu, W. H., Lee, B. H., Huang, Y. C., Hsu, Y. W. & Pan, T. M., 2012 Oct 1, In : Free Radical Biology and Medicine. 53, 9, p. 1643-1651 9 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
22 Citations (Scopus)

Antioxidant and anti-inflammatory effects of pigeon pea (Cajanus cajan L.) extracts on hydrogen peroxide- and lipopolysaccharide-treated RAW264.7 macrophages

Lai, Y. S., Hsu, W-H., Huang, J. J. & Wu, S. C., 2012 Dec 1, In : Food and Function. 3, 12, p. 1294-1301 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Buckwheat extracts (Fagopyrum tataricum) and rutin attenuate Th2 cytokines production and cellular allergic effects in vitro and in vivo

Shen, S. R., Hsu, W-H., Lee, C. C., Chang, W. C. & Wu, S. C., 2012 Oct 1, In : Journal of Functional Foods. 4, 4, p. 793-799 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Fagopyrum tataricum (Buckwheat) improved high-glucose-induced insulin resistance in mouse hepatocytes and diabetes in fructose-rich diet-induced mice

Lee, C. C., Hsu, W. H., Shen, S. R., Cheng, Y. H. & Wu, S. C., 2012 May 21, In : Experimental Diabetes Research. 2012, 375673.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Inhibition of leukemia proliferation by a novel polysaccharide identified from Monascus-fermented dioscorea via inducing differentiation

Lee, B. H., Hsu, W-H., Liao, T. H. & Pan, T. M., 2012 Jul 1, In : Food and Function. 3, 7, p. 758-764 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Monascus-fermented metabolite monascin suppresses inflammation via PPAR-γ regulation and JNK inactivation in THP-1 monocytes

Hsu, W. H., Lee, B. H., Liao, T. H., Hsu, Y. W. & Pan, T. M., 2012 May 1, In : Food and Chemical Toxicology. 50, 5, p. 1178-1186 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Monascus-fermented product monascin acts as a novel PPAR-γ ligand to suppress histamine-induced Th2 cytokines production thereby exerting anti-allergic activity

Hsu, W-H., Lee, B-H. & Pan, T-M., 2012, The ISEKI (Integrating Food Science and Engineering Knowledge Into the Food Chain)-Food Association (IFA). Palmerston North, New Zealand

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Monascus purpureus-fermented products and oral cancer: A review

Hsu, W-H. & Pan, T. M., 2012 Mar 1, In : Applied Microbiology and Biotechnology. 93, 5, p. 1831-1842 12 p.

Research output: Contribution to journalShort survey

19 Citations (Scopus)

Red Mold Rice against Hepatic Inflammatory Damage in Zn-deficient Rats

Lee, B. H., Hsu, W. H. & Pan, T. M., 2012 Jan 1, In : Journal of Traditional and Complementary Medicine. 2, 1, p. 52-60 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2011

A novel adjuvant therapeutic material: Chemoprevention of monascus-fermented product on oral cancer

Hsu, W-H. & Pan, T. M., 2011 Apr 1, Oral Cancer: Causes, Diagnosis and Treatment. Nova Science Publishers, Inc., p. 233-252 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Antihypertensive effects of Lactobacillus-fermented milk orally administered to spontaneously hypertensive rats

Liu, C. F., Tung, Y. T., Wu, C. L., Lee, B. H., Hsu, W-H. & Pan, T. M., 2011 May 11, In : Journal of Agricultural and Food Chemistry. 59, 9, p. 4537-4543 7 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Effects of red mold dioscorea on oral carcinogenesis in DMBA-induced hamster animal model

Hsu, W. H., Lee, B. H. & Pan, T. M., 2011 Jun 1, In : Food and Chemical Toxicology. 49, 6, p. 1292-1297 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Immunomodulatory and antioxidant potential of Lactobacillus exopolysaccharides

Liu, C. F., Tseng, K. C., Chiang, S. S., Lee, B. H., Hsu, W-H. & Pan, T. M., 2011 Sep 1, In : Journal of the Science of Food and Agriculture. 91, 12, p. 2284-2291 8 p.

Research output: Contribution to journalArticle

118 Citations (Scopus)

Inhibitory effects of dioscorea polysaccharide on TNF-α-induced insulin resistance in mouse FL83B cells

Lee, B. H., Hsu, W-H. & Pan, T. M., 2011 May 25, In : Journal of Agricultural and Food Chemistry. 59, 10, p. 5279-5285 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)