• 767 Citations
  • 16 h-Index
20052019
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Research Output 2005 2019

  • 767 Citations
  • 16 h-Index
  • 58 Article
  • 1 Review article
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Article
2019

H. pylori isolates with amino acid sequence polymorphisms as presence of both HtrA-L171 & CagL-Y58/E59 increase the risk of gastric cancer

Yeh, Y. C., Kuo, H. Y., Chang, W. L., Yang, H. B., Lu, C. C., Cheng, H. C., Wu, M. S. & Sheu, B. S., 2019 Jan 5, In : Journal of biomedical science. 26, 1, 4.

Research output: Contribution to journalArticle

Pylorus
Polymorphism
Stomach Neoplasms
Amino Acid Sequence
Amino Acids

High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma

Lin, C. H., Li, H. Y., Liu, Y. P., Kuo, P. F., Wang, W. C., Lin, F. C., Chang, W. L., Sheu, B. S., Wang, Y. C., Hung, W. C., Cheng, H. C., Yao, Y. C., Calkins, M. J., Hsiao, M. & Lu, P. J., 2019 Jan 1, In : Therapeutic Advances in Medical Oncology. 11

Research output: Contribution to journalArticle

Open Access
Stem Cells
Fursultiamin
Neoplasms
Therapeutics
Neoplastic Stem Cells

Multifocal gastrointestinal varices: a rare manifestation of immunoglobulin G4-related disease

Lin, T-C. & Chang, W-L., 2019 Apr 3, In : Postgraduate Medicine. 131, 3, p. 176-181 6 p.

Research output: Contribution to journalArticle

Varicose Veins
Immunoglobulins
Hemorrhage
Retroperitoneal Fibrosis
Melena

Radiotherapy for inferior vena cava tumor thrombus in patients with hepatocellular carcinoma

Pao, T. H., Hsueh, W. T., Chang, W. L., Chiang, N. J., Lin, Y. J., Liu, Y. S. & Lin, F. C., 2019 Jun 10, In : BMC cancer. 19, 1, 560.

Research output: Contribution to journalArticle

Open Access
Inferior Vena Cava
Hepatocellular Carcinoma
Thrombosis
Radiotherapy
Neoplasms
2 Citations (Scopus)
Open Access
Esophageal Neoplasms
DNA Repair
DNA Damage
Repair
Down-Regulation
Metaplasia
Helicobacter pylori
Stomach Neoplasms
MicroRNAs
spasmolytic polypeptide
2018
2 Citations (Scopus)

A training program of a new simplified classification of magnified narrow band imaging for superficial esophageal squamous cell carcinoma

Wang, W. L., Chiu, S. Y. H., Lee, C. T., Tseng, C. H., Chen, C. C., Han, M. L., Chung, C. S., Hsieh, P. H., Chang, W-L., Wu, P. H., Hsu, W. H., Yen, H. H., Wang, H. P. & Chang, C. Y., 2018 Jun 1, In : Journal of Gastroenterology and Hepatology (Australia). 33, 6, p. 1248-1255 8 p.

Research output: Contribution to journalArticle

Narrow Band Imaging
Education
Light
Endoscopy
Blood Vessels
1 Citation (Scopus)

Survey of the adherence to the consensus of gastroesophageal reflux disease before and after the implementation course

Liou, J. M., Sheu, B-S., Lee, Y. C., Cheng, H-C., Chang, W-L., Wu, D. C., Hsu, P. I., Wu, C. Y., Wu, M. S., Chiu, C. T. & Lin, J. T., 2018 May 1, In : Journal of the Formosan Medical Association. 117, 5, p. 440-449 10 p.

Research output: Contribution to journalArticle

Gastroesophageal Reflux
Medical Education
Physicians
Surveys and Questionnaires
Gastroenterology
1 Citation (Scopus)

The implementation of the consensus on the management of Helicobacter pylori and barriers to consensus

Cheng, H-C., Liou, J. M., Luo, J. C., Chiu, C. T., Wu, M. S., Lee, Y. C., Wu, C. Y., Wu, D. C., Hsu, P. I., Chang, C. C., Chang, W-L., Lin, J. T. & Sheu, B-S., 2018 Oct 1, In : Helicobacter. 23, 5, e12533.

Research output: Contribution to journalArticle

Continuing Medical Education
Helicobacter pylori
Consensus
Motivation
District Hospitals
2017
3 Citations (Scopus)
Chemoradiotherapy
DNA Methylation
Biomarkers
Methylation
Therapeutics
20 Citations (Scopus)

Consensus on the clinical management, screening-to-treat, and surveillance of Helicobacter pylori infection to improve gastric cancer control on a nationwide scale

Sheu, B-S., Wu, M. S., Chiu, C. T., Lo, J. C., Wu, D. C., Liou, J. M., Wu, C. Y., Cheng, H-C., Lee, Y. C., Hsu, P. I., Chang, C. C., Chang, W-L. & Lin, J. T., 2017 Jun 1, In : Helicobacter. 22, 3, e12368.

Research output: Contribution to journalArticle

Helicobacter Infections
Helicobacter pylori
Stomach Neoplasms
Taiwan
Chemoprevention
1 Citation (Scopus)
Pylorus
Medical problems
Type 2 Diabetes Mellitus
Stomach
Inflammation
2 Citations (Scopus)

Osteopontin polymorphism increases gastric precancerous intestinal metaplasia susceptibility in Helicobacter pylori infected male

Chang, W-L., Lin, M-Y., Kuo, H. Y., Yang, H. B., Cheng, H-C., Lu, C-C. & Sheu, B-S., 2017 Jul 1, In : Future Oncology. 13, 16, 0006.

Research output: Contribution to journalArticle

Osteopontin
Metaplasia
Helicobacter pylori
Stomach
Haplotypes
3 Citations (Scopus)

Serum Level of Trefoil Factor 2 can Predict the Extent of Gastric Spasmolytic Polypeptide-Expressing Metaplasia in the H. pylori-Infected Gastric Cancer Relatives

Kuo, H. Y., Chang, W. L., Yeh, Y. C., Tsai, Y. C., Wu, C. T., Cheng, H. C., Yang, H. B., Lu, C. C. & Sheu, B. S., 2017 Feb 1, In : Helicobacter. 22, 1, e12320.

Research output: Contribution to journalArticle

Pylorus
Metaplasia
Stomach Neoplasms
Stomach
Serum
5 Citations (Scopus)
Levofloxacin
Helicobacter pylori
Type 2 Diabetes Mellitus
Clarithromycin
Helicobacter Infections
5 Citations (Scopus)

The corpus-predominant gastritis index can be an early and reversible marker to identify the gastric cancer risk of Helicobacter pylori-infected nonulcer dyspepsia

Cheng, H. C., Tsai, Y. C., Yang, H. B., Yeh, Y. C., Chang, W. L., Kuo, H. Y., Lu, C. C. & Sheu, B. S., 2017 Aug, In : Helicobacter. 22, 4, e12385.

Research output: Contribution to journalArticle

Dyspepsia
Gastritis
Helicobacter pylori
Stomach Neoplasms
Metaplasia
2016
2 Citations (Scopus)

Low disabled-2 expression promotes tumor progression and determines poor survival and high recurrence of esophageal squamous cell carcinoma

Wang, W. L., Chang, W-L., Yang, H. B., Wang, Y. C., Chang, I. W., Lee, C. T., Chang, C. Y., Lin, J. T. & Sheu, B-S., 2016 Jan 1, In : Oncotarget. 7, 44, p. 71169-71181 13 p.

Research output: Contribution to journalArticle

Recurrence
Survival
Neoplasms
Epithelial-Mesenchymal Transition
Biomarkers
13 Citations (Scopus)

MiR-193a-5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma

Lin, C. H., Tsai, C. H., Yeh, C. T., Liang, J. L., Hung, W. C., Lin, F-C., Chang, W-L., Li, H. Y., Yao, Y. C., Hsu, T. I., Lee, Y. C., Wang, Y-C., Sheu, B-S., Lai, W-W., Calkins, M. J., Hsiao, M. & Lu, P-J., 2016 Jan 1, In : Oncotarget. 7, 26, p. 39680-39693 14 p.

Research output: Contribution to journalArticle

Radiation Tolerance
Therapeutics
Esophageal Neoplasms
Animal Disease Models
Recurrence
3 Citations (Scopus)

Predictors for postoperative esophageal stricture after balloon-based radiofrequency ablation for early esophageal squamous neoplasia: A multicenter validation study

Wang, W. L., Chang, I. W., Chen, C. C., Chang, W. L., Chu, Y. Y., Wu, P. H., Tai, W. C., Chen, P. Y., Hsieh, P. H., Chung, C. S., Chang, C. Y., Lin, J. T., Wang, H. P. & Lee, C. T., 2016 Jan 1, In : Therapeutic Advances in Gastroenterology. 9, 3, p. 257-264 8 p.

Research output: Contribution to journalArticle

Esophageal Stenosis
Validation Studies
Multicenter Studies
Pathologic Constriction
Squamous Cell Neoplasms
2015
3 Citations (Scopus)

Consensus of gastroesophageal reflux disease in Taiwan with endoscopy-based approach covered by National Health Insurance

Sheu, B-S., Chiu, C. T., Lee, Y. C., Chang, C. Y., Wu, D. C., Liou, J. M., Wu, M. S., Chang, W-L., Wu, C. Y. & Lin, J. T., 2015 Sep 1, In : Advances in Digestive Medicine. 2, 3, p. 85-94 10 p., 79.

Research output: Contribution to journalArticle

National Health Programs
Gastroesophageal Reflux
Taiwan
Endoscopy
Proton Pump Inhibitors
4 Citations (Scopus)
Pylorus
Metaplasia
Polymorphism
Interleukin-10
Stomach Neoplasms
3 Citations (Scopus)

Intracellular Osteopontin Induced by CagA-positive Helicobacter pylori Promotes Beta-catenin Accumulation and Interleukin-8 Secretion in Gastric Epithelial cells

Chang, W. L., Yang, H. B., Cheng, H. C., Yeh, Y. C., Kao, C. Y., Wu, J. J., Lu, C. C. & Sheu, B. S., 2015 Dec 1, In : Helicobacter. 20, 6, p. 476-484 9 p.

Research output: Contribution to journalArticle

Osteopontin
beta Catenin
Pylorus
Interleukin-8
Helicobacter pylori
15 Citations (Scopus)

Quantification of tumor infiltrating Foxp3+ regulatory T cells enables the identification of high-risk patients for developing synchronous cancers over upper aerodigestive tract

Wang, W. L., Chang, W. L., Yang, H. B., Chang, I. W., Lee, C. T., Chang, C. Y., Lin, J. T. & Sheu, B. S., 2015 Jul 1, In : Oral Oncology. 51, 7, p. 698-703 6 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Neoplasms
Squamous Cell Carcinoma
Interleukin-10
Chemokine CCL22
7 Citations (Scopus)
Chemoradiotherapy
Tomography
Therapeutics
Esophageal Stenosis
Endoscopy
2014
15 Citations (Scopus)
Esomeprazole
Peptic Ulcer
Intravenous Infusions
Hemorrhage
Ulcer
22 Citations (Scopus)

Heteroresistance of Helicobacter pylori from the same patient prior to antibiotic treatment

Kao, C. Y., Lee, A. Y., Huang, A. H., Song, P. Y., Yang, Y., Sheu, S. M., Chang, W-L., Sheu, B-S. & Wu, J. J., 2014 Jan 1, In : Infection, Genetics and Evolution. 23, p. 196-202 7 p.

Research output: Contribution to journalArticle

Helicobacter pylori
antibiotics
Anti-Bacterial Agents
antibiotic resistance
clarithromycin
36 Citations (Scopus)

Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression

Kuo, I. Y., Wu, C. C., Chang, J. M., Huang, Y. L., Lin, C. H., Yan, J. J., Sheu, B-S., Lu, P-J., Chang, W-L., Lai, W-W. & Wang, Y-C., 2014 Aug 1, In : International Journal of Cancer. 135, 3, p. 563-573 11 p.

Research output: Contribution to journalArticle

Esophageal Neoplasms
Gene Regulatory Networks
Genes
Proteins
Neoplasm Metastasis
20 Citations (Scopus)

Prognostic CpG methylation biomarkers identified by methylation array in esophageal squamous cell carcinoma patients

Kuo, I. Y., Chang, J. M., Jiang, S. S., Chen, C. H., Chang, I. S., Sheu, B-S., Lu, P-J., Chang, W-L., Lai, W-W. & Wang, Y-C., 2014 May 30, In : International Journal of Medical Sciences. 11, 8, p. 779-787 9 p.

Research output: Contribution to journalArticle

Methylation
Biomarkers
Genes
Esophageal Squamous Cell Carcinoma
Neoplasms
2013
12 Citations (Scopus)

Concomitantly elevated serum matrix metalloproteinases 3 and 9 can predict survival of synchronous squamous cell carcinoma of the upper aero-digestive tract

Wang, W. L., Chang, W. L., Yeh, Y. C., Lee, C. T., Chang, C. Y., Lin, J. T. & Sheu, B. S., 2013 Jun 1, In : Molecular Carcinogenesis. 52, 6, p. 438-445 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 3
Matrix Metalloproteinase 9
Gastrointestinal Tract
Squamous Cell Carcinoma
Survival
12 Citations (Scopus)
Achlorhydria
pylorus
Pylorus
integrins
Integrins
7 Citations (Scopus)
Hypoalbuminemia
Peptic Ulcer
Albumins
Hospitalization
Hemorrhage
6 Citations (Scopus)

Long-term celecoxib can prevent the progression of persistent gastric intestinal metaplasia after H. pylori eradication

Sheu, B. S., Tsai, Y. C., Wu, C. T., Chang, W. L., Cheng, H. C. & Yang, H. B., 2013 Apr 1, In : Helicobacter. 18, 2, p. 117-123 7 p.

Research output: Contribution to journalArticle

Celecoxib
Pylorus
Metaplasia
Stomach
Control Groups
27 Citations (Scopus)

The corpus-predominant gastritis index may serve as an early marker of helicobacter pylori-infected patients at risk of gastric cancer

Tsai, Y. C., Hsiao, W. H., Yang, H. B., Cheng, H-C., Chang, W-L., Lu, C-C. & Sheu, B-S., 2013 May 1, In : Alimentary Pharmacology and Therapeutics. 37, 10, p. 969-978 10 p.

Research output: Contribution to journalArticle

Gastritis
Helicobacter pylori
Stomach Neoplasms
Metaplasia
Stomach
2012
5 Citations (Scopus)
Peptic Esophagitis
Los Angeles
Genotype
Tablets
Therapeutics
5 Citations (Scopus)
Matrix Metalloproteinase 1
Tissue Inhibitor of Metalloproteinase-1
Matrix Metalloproteinase Inhibitors
Stomach Ulcer
Matrix Metalloproteinases
14 Citations (Scopus)

Gemifloxacin can partially overcome quinolone resistance of H. pylori with gyrA mutation in Taiwan

Chang, W. L., Kao, C. Y., Wu, C. T., Huang, A. H., Wu, J. J., Yang, H. B., Cheng, H. C. & Sheu, B. S., 2012 Jun 1, In : Helicobacter. 17, 3, p. 210-215 6 p.

Research output: Contribution to journalArticle

Levofloxacin
Pylorus
Quinolones
Taiwan
Mutation
16 Citations (Scopus)

Higher Motility Enhances Bacterial Density and Inflammatory Response in Dyspeptic Patients Infected with Helicobacter pylori

Kao, C. Y., Sheu, B. S., Sheu, S. M., Yang, H. B., Chang, W. L., Cheng, H. C. & Wu, J. J., 2012 Dec 1, In : Helicobacter. 17, 6, p. 411-416 6 p.

Research output: Contribution to journalArticle

Helicobacter pylori
Stomach
Cardia
Flagella
Mucus
2011
29 Citations (Scopus)

H. pylori cagL amino acid sequence polymorphism Y58E59 induces a corpus shift of gastric integrin α5β1 related with gastric carcinogenesis

Yeh, Y. C., Chang, W. L., Yang, H. B., Cheng, H. C., Wu, J. J. & Sheu, B. S., 2011 Oct 1, In : Molecular Carcinogenesis. 50, 10, p. 751-759 9 p.

Research output: Contribution to journalArticle

Pylorus
Helicobacter pylori
Integrins
Amino Acid Sequence
Stomach
19 Citations (Scopus)

Helicobacter pylori with stronger intensity of CagA phosphorylation lead to an increased risk of gastric intestinal metaplasia and cancer

Chuang, C-H., Yang, H. B., Sheu, S. M., Hung, K. H., Wu, J. J., Cheng, H-C., Chang, W-L. & Sheu, B-S., 2011 May 31, In : BMC microbiology. 11, 121.

Research output: Contribution to journalArticle

Intestinal Neoplasms
Metaplasia
Helicobacter pylori
Stomach Neoplasms
Phosphorylation
16 Citations (Scopus)
Osteopontin
Metaplasia
Helicobacter Infections
Helicobacter pylori
Stomach
1 Citation (Scopus)
Peptic Esophagitis
Los Angeles
Hemoglobins
Esomeprazole
Stomach
7 Citations (Scopus)
Endosonography
Pathologic Constriction
Survival
Neoplasms
Therapeutics
1 Citation (Scopus)
Serum Response Factor
Stomach Ulcer
Up-Regulation
Hemorrhage
Morbidity
2010
23 Citations (Scopus)
Peptic Esophagitis
Los Angeles
Body Mass Index
Genotype
Proton Pump Inhibitors
8 Citations (Scopus)
Matrix Metalloproteinase 3
Pylorus
Duodenal Ulcer
Genotype
Tissue Inhibitor of Metalloproteinase-1
2009
3 Citations (Scopus)
Gastrostomy
Sputum
Wounds and Injuries
Infection
Pulsed Field Gel Electrophoresis
31 Citations (Scopus)

Gender difference of circulating ghrelin and leptin concentrations in Chronic Helicobacter pylori infection

Chuang, C-H., Sheu, B-S., Yang, H. B., Lee, S. C., Kao, A. W., Cheng, H-C., Chang, W-L. & Yao, W-J., 2009 Feb 1, In : Helicobacter. 14, 1, p. 54-60 7 p.

Research output: Contribution to journalArticle

Ghrelin
Helicobacter Infections
Leptin
Helicobacter pylori
Gastritis
40 Citations (Scopus)
Esomeprazole
Peptic Esophagitis
Pylorus
Metaplasia
Helicobacter pylori
7 Citations (Scopus)
Peptic Esophagitis
Pylorus
Duodenal Ulcer
Body Mass Index
Helicobacter pylori
75 Citations (Scopus)

Prevalence of primary fluoroquinolone resistance among clinical isolates of Helicobacter pylori at a University Hospital in Southern Taiwan

Hung, K. H., Sheu, B. S., Chang, W. L., Wu, H. M., Liu, C. C. & Wu, J. J., 2009 Feb 1, In : Helicobacter. 14, 1, p. 61-65 5 p.

Research output: Contribution to journalArticle

Fluoroquinolones
Taiwan
Helicobacter pylori
Levofloxacin
Ciprofloxacin