• 11729 Citations
  • 49 h-Index
19952019
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Research Output 1995 2019

2019
Open Access
Klebsiella pneumoniae
Taiwan
Pseudomonas aeruginosa
Intensive Care Units
Imipenem
Dengue
Infection
Therapeutics
Anti-Bacterial Agents
Levofloxacin
3 Citations (Scopus)

Characteristics of scrub typhus, murine typhus, and Q fever among elderly patients: Prolonged prothrombin time as a predictor for severity

Chang, K., Lee, N-Y., Ko, W-C., Lin, W. R., Chen, Y. H., Tsai, J. J., Chen, T. C., Lin, C. Y., Chang, Y. T. & Lu, P. L., 2019 Feb 1, In : Journal of Microbiology, Immunology and Infection. 52, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

Endemic Flea-Borne Typhus
Scrub Typhus
Q Fever
Prothrombin Time
Multivariate Analysis

Clinical Benefit of Empiric High-dose Levofloxacin Therapy for Adults With Community-onset Enterobacteriaceae Bacteremia

Lee, C. C., Yang, C-Y., Lee, C. H., Hsieh, C-C., Hong, M-Y., Tang, H. J. & Ko, W-C., 2019 Jan 1, (Accepted/In press) In : Clinical Therapeutics.

Research output: Contribution to journalArticle

Levofloxacin
Enterobacteriaceae
Bacteremia
Mortality
Therapeutics
4 Citations (Scopus)

Clinical manifestations of candidemia caused by uncommon Candida species and antifungal susceptibility of the isolates in a regional hospital in Taiwan, 2007–2014

Liu, W. L., Lai, C. C., Li, M-C., Wu, C. J., Ko, W-C., Hung, Y. L., Tang, H. J. & Hsueh, P. R., 2019 Aug 1, In : Journal of Microbiology, Immunology and Infection. 52, 4, p. 612-619 8 p.

Research output: Contribution to journalArticle

Candidemia
Taiwan
Candida
Azoles
Microbial Sensitivity Tests

Corrigendum: The ATP-P2X7 Signaling Axis Is an Essential Sentinel for Intracellular Clostridium difficile Pathogen-Induced Inflammasome Activation

Liu, Y. H., Chang, Y. C., Chen, L. K., Su, P. A., Ko, W-C., Tsai, Y-S., Chen, Y. H., Lai, H. C., Wu, C. Y., Hung, Y. P. & Tsai, P-J., 2019 Jan 1, In : Frontiers in Cellular and Infection Microbiology. 9, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Inflammasomes
Clostridium difficile
Adenosine Triphosphate
corrigendum
cyhalothrin
21 Citations (Scopus)
Tenofovir
Lamivudine
HIV Infections
HIV-1
Pharmaceutical Preparations

High smoking prevalence among HIV-positive individuals: A systematic review and meta-analysis

Lindayani, L., Yeh, C. Y., Ko, W-C. & Ko, N-Y., 2019 Jan 1, (Accepted/In press) In : Journal of Substance Use.

Research output: Contribution to journalReview article

Meta-Analysis
smoking
Smoking
HIV
Cross-Sectional Studies
1 Citation (Scopus)

Implementation of a national quality improvement program to enhance hand hygiene in nursing homes in Taiwan

for Infection Control Society of Taiwan, 2019 Apr 1, In : Journal of Microbiology, Immunology and Infection. 52, 2, p. 345-351 7 p.

Research output: Contribution to journalArticle

Hand Hygiene
Quality Improvement
Nursing Homes
Taiwan
Cross Infection
1 Citation (Scopus)

National bundle care program implementation to reduce ventilator-associated pneumonia in intensive care units in Taiwan

for the Infection Control Society of Taiwan, 2019 Aug 1, In : Journal of Microbiology, Immunology and Infection. 52, 4, p. 592-597 6 p.

Research output: Contribution to journalArticle

Patient Care Bundles
Ventilator-Associated Pneumonia
Taiwan
Intensive Care Units
Mechanical Ventilators

Nationwide surveillance of antimicrobial resistance among clinically important Gram-negative bacteria, with an emphasis on carbapenems and colistin: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART) in 2018

Lee, Y. L., Lu, M. C., Shao, P. L., Lu, P. L., Chen, Y. H., Cheng, S. H., Ko, W-C., Lin, C. Y., Wu, T. S., Yen, M. Y., Wang, L. S., Liu, C. P., Lee, W. S., Shi, Z. Y., Chen, Y. S., Wang, F. D., Tseng, S. H., Lin, C. N., Chen, Y. H., Sheng, W. H. & 3 others, Lee, C. M., Liao, M. H. & Hsueh, P. R., 2019 Sep 1, In : International journal of antimicrobial agents. 54, 3, p. 318-328 11 p.

Research output: Contribution to journalArticle

Colistin
Carbapenems
Klebsiella pneumoniae
Gram-Negative Bacteria
Taiwan

Postoperative Mycobacteroides abscessus subsp. abscessus endophthalmitis: Clinical analysis of 12 clustered adults and a proposed therapeutic algorithm

Hung, J-H., Ko, W-C., Chen, C. Y., Lin, S-H., Wu, C. L., Hsu, S-M., Teng, Y. T., Wang, S. H., Tseng, S. H., Huang, F-C., Lai, C. C., Chen, C. L., Lai, C. H., Chen, P-L. & Jou-Chen Huang, E., 2019 Jan 1, (Accepted/In press) In : Journal of Microbiology, Immunology and Infection.

Research output: Contribution to journalArticle

Endophthalmitis
Temazepam
Vitrectomy
Taiwan
Nontuberculous Mycobacteria
3 Citations (Scopus)

Predominance of methicillin-resistant Staphylococcus aureus in the residents and environments of long-term care facilities in Taiwan

Infection Control Society of Taiwan, 2019 Feb 1, In : Journal of Microbiology, Immunology and Infection. 52, 1, p. 62-74 13 p.

Research output: Contribution to journalArticle

Long-Term Care
Methicillin-Resistant Staphylococcus aureus
Carbapenems
Taiwan
Acinetobacter baumannii

Prevalence and risk factors for colonization by extended-spectrum β-lactamase-producing or ST 131 escherichia coli among asymptomatic adults in community settings in Southern Taiwan

Wu, P. C., Wang, J-L., Hsueh, P. R., Lin, P. H., Cheng, M. F., Huang, I. F., Chen, Y. S., Lee, S. S. J., Guang-Yuan, M., Yu, H. C., Hsu, C. L., Wang, F. W., Chen, C. S., Hung, C. H. & Ko, W-C., 2019 Jan 1, In : Infection and Drug Resistance. 12, p. 1063-1071 9 p.

Research output: Contribution to journalArticle

Open Access
Taiwan
Escherichia coli
Odds Ratio
Confidence Intervals
Colonic Polyps

Randomized Noninferiority Trial of Cefoperazone-Sulbactam versus Cefepime in the Treatment of Hospital-Acquired and Healthcare-Associated Pneumonia

Liu, J. W., Chen, Y. H., Lee, W. S., Lin, J. C., Huang, C. T., Lin, H. H., Liu, Y. C., Chuang, Y. C., Tang, H. J., Chen, Y. S., Ko, W-C., Lu, M. C. & Wang, F. D., 2019 Aug 1, In : Antimicrobial agents and chemotherapy. 63, 8

Research output: Contribution to journalArticle

Cefoperazone
Sulbactam
Pneumonia
Delivery of Health Care
Therapeutics

Seroepidemiology of dengue virus infection among adults during the ending phase of a severe dengue epidemic in southern Taiwan, 2015

Chien, Y-W., Huang, H. M., Ho, T. C., Tseng, F. C., Ko, N-Y., Ko, W-C. & Perng, G-C., 2019 Apr 24, In : BMC Infectious Diseases. 19, 1, 338.

Research output: Contribution to journalArticle

Open Access
Severe Dengue
Dengue Virus
Virus Diseases
Taiwan
Dengue

Seroprevalence of zika and dengue virus antibodies among migrant workers, taiwan, 2017

Perng, G-C., Ho, T. C., Shih, H-I., Lee, C. H., Huang, P. W., Chung, C. H., Ko, N-Y., Ko, W-C. & Chien, Y-W., 2019 Apr 1, In : Emerging infectious diseases. 25, 4, p. 814-816 3 p.

Research output: Contribution to journalArticle

Open Access
Southeastern Asia
Dengue Virus
Seroepidemiologic Studies
Taiwan
Antibodies
Propensity Score
Bacteremia
Mortality
Therapeutics
Infection

Susceptibility rates of clinically important bacteria collected from intensive care units against colistin, carbapenems, and other comparative agents: Results from surveillance of multicenter antimicrobial resistance in Taiwan (SMART)

Lai, C. C., Chen, Y. S., Lee, N-Y., Tang, H. J., Lee, S. S. J., Lin, C. F., Lu, P. L., Wu, J. J., Ko, W-C., Lee, W. S. & Hsueh, P. R., 2019 Jan 1, In : Infection and Drug Resistance. 12, p. 627-640 14 p.

Research output: Contribution to journalArticle

Open Access
Colistin
Carbapenems
Taiwan
Intensive Care Units
Bacteria
2018
2 Citations (Scopus)

Are we ready for the global emergence of multidrug-resistant Candida auris in Taiwan?

Lu, P. L., Liu, W. L., Lo, H. J., Wang, F. D., Ko, W-C., Hsueh, P. R., Ho, M. W., Liu, C. E., Chen, Y. H., Chen, Y. C., Chuang, Y. C. & Chang, S. C., 2018 Jun 1, In : Journal of the Formosan Medical Association. 117, 6, p. 462-470 9 p.

Research output: Contribution to journalReview article

Taiwan
Candida
Disease Outbreaks
Delivery of Health Care
Hospital Laboratories
3 Citations (Scopus)

Carbapenem-resistant enterobacteriaceae infections: Taiwan aspects

Jean, S. S., Lee, N-Y., Tang, H. J., Lu, M. C., Ko, W-C. & Hsueh, P. R., 2018 Nov 27, In : Frontiers in Microbiology. 9, NOV, 2888.

Research output: Contribution to journalReview article

Enterobacteriaceae Infections
Carbapenems
Taiwan
Enterobacteriaceae
Klebsiella pneumoniae
2 Citations (Scopus)

Changing seroprevalence of hepatitis C virus infection among HIV-positive patients in Taiwan

Li, C-W., Yang, C. J., Sun, H. Y., Tsai, M. S., Lin, S. P., Lin, T. Y., Cheng, C. Y., Lee, Y. C., Huang, Y. S., Liu, C. E., Lee, Y. T., Tang, H. J., Wang, N. C., Cheng, S. H., Ko, W-C. & Hung, C. C., 2018 Mar 1, In : PloS one. 13, 3, e0194149.

Research output: Contribution to journalArticle

Hepatitis C virus
Human immunodeficiency virus
Seroepidemiologic Studies
HIV infections
Virus Diseases
4 Citations (Scopus)

Clinical and molecular features of MDR livestock-associated MRSA ST9 with staphylococcal cassette chromosome mecXII in humans

Chen, C. J., Lauderdale, T. L. Y., Lu, C. T., Chuang, Y. Y., Yang, C. C., Wu, T. S., Lee, C. Y., Lu, M. C., Ko, W-C. & Huang, Y. C., 2018 Jan 1, In : Journal of Antimicrobial Chemotherapy. 73, 1, p. 33-40 8 p., dkx357.

Research output: Contribution to journalArticle

Livestock
Methicillin-Resistant Staphylococcus aureus
Chromosomes
Swine
Chromosomes, Human, Pair 7
3 Citations (Scopus)

Clinical characteristics of patients with bacteraemia due to the emergence of mcr-1-harbouring Enterobacteriaceae in humans and pigs in Taiwan

Infection Control Society of Taiwan, 2018 Nov 1, In : International journal of antimicrobial agents. 52, 5, p. 651-657 7 p.

Research output: Contribution to journalArticle

Enterobacteriaceae
Bacteremia
Taiwan
Klebsiella pneumoniae
Swine
2 Citations (Scopus)
Clostridium Infections
Clostridium difficile
Taiwan
Health Facilities
Community Health Services

Corrigendum to “Rates of susceptibility of carbapenems, ceftobiprole, and colistin against clinically important bacteria collected from intensive care units in 2007: Results from the Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)” [J Microbiol Immunol Infect 49 (2016) 969–976] (S1684118215000213) (10.1016/j.jmii.2014.12.008))

Jean, S. S., Lee, W. S., Yu, K. W., Liao, C. H., Hsu, C. W., Chang, F. Y., Ko, W-C., Chen, R. J., Wu, J. J., Chen, Y. H., Chen, Y. S., Liu, J. W., Lu, M. C., Lam, C., Liu, C. Y. & Hsueh, P. R., 2018 Jun 1, In : Journal of Microbiology, Immunology and Infection. 51, 3, p. 423-424 2 p.

Research output: Contribution to journalComment/debate

Colistin
Carbapenems
Taiwan
Intensive Care Units
Emergency Medicine
1 Citation (Scopus)
Klebsiella
Pseudomonas
Pneumonia
Bacteremia
Febrile Neutropenia

Evaluating virulence and pathogenesis of Aeromonas Infection in a Caenorhabditis elegans model

Chen, Y. W., Ko, W-C., Chen, C-S. & Chen, P-L., 2018 Dec 1, In : Journal of Visualized Experiments. 2018, 142, e58768.

Research output: Contribution to journalArticle

Aeromonas
Caenorhabditis elegans
Toxicity
Virulence
Poisons
2 Citations (Scopus)

Implementation of a national bundle care program to reduce central line-associated bloodstream infections in intensive care units in Taiwan

for the Infection Control Society of Taiwan, 2018 Oct 1, In : Journal of Microbiology, Immunology and Infection. 51, 5, p. 666-671 6 p.

Research output: Contribution to journalArticle

Patient Care Bundles
Taiwan
Intensive Care Units
Infection
Catheters
4 Citations (Scopus)

In vitro activity of ceftazidime–avibactam, ceftolozane–tazobactam, and other comparable agents against clinically important Gram-negative bacilli: Results from the 2017 surveillance of multicenter antimicrobial resistance in Taiwan (SMART)

Jean, S. S., Lu, M. C., Shi, Z. Y., Tseng, S. H., Wu, T. S., Lu, P. L., Shao, P. L., Ko, W-C., Wang, F. D. & Hsueh, P. R., 2018 Jan 1, In : Infection and Drug Resistance. 11, p. 1983-1992 10 p.

Research output: Contribution to journalArticle

Klebsiella pneumoniae
Taiwan
Bacillus
Shigella
Escherichia coli
2 Citations (Scopus)

In vitro and in vivo antibacterial activity of tigecycline against Vibrio vulnificus

Tang, H. J., Chen, C. C., Lai, C. C., Zhang, C. C., Weng, T. C., Chiu, Y. H., Toh, H. S., Chiang, S. R., Yu, W. L., Ko, W-C. & Chuang, Y. C., 2018 Feb 1, In : Journal of Microbiology, Immunology and Infection. 51, 1, p. 76-81 6 p.

Research output: Contribution to journalArticle

Vibrio vulnificus
Cefotaxime
Minocycline
tigecycline
In Vitro Techniques
5 Citations (Scopus)

Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model

Yang, H. T., Chen, J-W., Rathod, J., Jiang, Y. Z., Tsai, P-J., Hung, Y. P., Ko, W-C., Paredes-Sabja, D. & Huang, I-H., 2018 Jan 17, In : Frontiers in Microbiology. 8, JAN, 2635.

Research output: Contribution to journalArticle

lauric acid
Clostridium difficile
Inflammation
Clostridium Infections
Growth

Legionnaires’ disease at a medical center in southern Taiwan

Hung, T. L., Li, M-C., Wang, L. R., Liu, C-C., Li, C-W., Chen, P-L., Syue, L-S., Lee, N-Y. & Ko, W-C., 2018 Jun 1, In : Journal of Microbiology, Immunology and Infection. 51, 3, p. 352-358 7 p.

Research output: Contribution to journalArticle

Legionnaires' Disease
Taiwan
Pneumonia
Caregivers
Delivery of Health Care
2 Citations (Scopus)

Less severe but prolonged course of acute hepatitis a in Human Immunodeficiency Virus (HIV)-infected patients compared with HIV-uninfected patients during an outbreak: A multicenter observational study

Lee, Y. L., Chen, G. J., Chen, N. Y., Liou, B. H., Wang, N. C., Lee, Y. T., Yang, C. J., Huang, Y. S., Tang, H. J., Huang, S. S., Lin, Y. C., Cheng, C. Y., Lee, C. H., Chen, T. C., Wu, T. S., Liu, C. E., Lu, P. L., Hung, C. C., Lee, Y. C., Cheng, C. Y. & 22 others, Cheng, S. H., Huang, Y. S., Lee, Y. T., Lin, C. C., Lin, S. P., Hsieh, C. Y., Wang, H. W., Ho, M. W., Liu, C. E., Lee, Y. L., Lee, Y. C., Tang, H. J., Ku, H. C., Li, C-W., Lee, N-Y., Ko, W-C., Lu, P. L., Chen, Y. H., Lin, H. H., Huang, W. C., Lee, C. H. & Che, T. C., 2018 Oct 30, In : Clinical Infectious Diseases. 67, 10, p. 1595-1602 8 p.

Research output: Contribution to journalArticle

Hepatitis
Multicenter Studies
Observational Studies
Disease Outbreaks
Hepatitis A
2 Citations (Scopus)

Methicillin-resistant Staphylococcus aureus sequence type 45 with high rates of ciprofloxacin and tetracycline resistance in the residents and environments of long-term care facilities in Taiwan

Lai, C. C., Lee, C. M., Chiang, H. T., Lu, M. C., Wang, L. F., Tsai, T. L., Kang, M. Y., Jan, Y. N., Lo, Y. T., Ko, W-C., Tseng, S. H. & Hsueh, P. R., 2018 Mar 1, In : Journal of Infection. 76, 3, p. 305-307 3 p.

Research output: Contribution to journalLetter

Tetracycline Resistance
Long-Term Care
Methicillin-Resistant Staphylococcus aureus
Ciprofloxacin
Taiwan
2 Citations (Scopus)
Ribotyping
Clostridium difficile
Doxycycline
Metronidazole
Taiwan
1 Citation (Scopus)

Oligonucleotide array and VITEK matrix-assisted laser desorption ionization-time of flight mass spectrometry in species identification of blood yeast isolates

Li, M-C., Chang, T. C., Chen, H. M., Wu, C. J., Su, S. L., Lee, S. S. J., Chen, P-L., Lee, N-Y., Lee, C. C., Li, C-W., Syue, L-S. & Ko, W-C., 2018 Jan 26, In : Frontiers in Microbiology. 9, JAN, 51.

Research output: Contribution to journalArticle

Oligonucleotide Array Sequence Analysis
Candida
Mass Spectrometry
Lasers
Yeasts
2 Citations (Scopus)

Photodynamic inactivation of methicillin-resistant Staphylococcus aureus by indocyanine green and near infrared light

Wong, T-W., Wu, E. C., Ko, W-C., Lee, C. C., Hor, L. I. & Huang, I-H., 2018 Mar 1, In : Dermatologica Sinica. 36, 1, p. 8-15 8 p.

Research output: Contribution to journalArticle

Indocyanine Green
Methicillin-Resistant Staphylococcus aureus
Light
Photochemotherapy
Singlet Oxygen
4 Citations (Scopus)

Prolonged persistence of IgM against dengue virus detected by commonly used commercial assays

Chien, Y-W., Liu, Z. H., Tseng, F. C., Ho, T. C., Guo, H-R., Ko, N-Y., Ko, W-C. & Perng, G-C., 2018 Apr 2, In : BMC Infectious Diseases. 18, 1, 156.

Research output: Contribution to journalArticle

Dengue Virus
Immunoglobulin M
Dengue
Enzyme-Linked Immunosorbent Assay
Taiwan
3 Citations (Scopus)
Proteus mirabilis
Klebsiella
Bacteremia
Escherichia coli
Comorbidity
3 Citations (Scopus)

QuantiFERON-TB gold plus is a more sensitive screening tool than QuantiFERON-TB gold in-tube for latent tuberculosis infection among older adults in long-term care facilities

Chien, J. Y., Chiang, H. T., Lu, M. C., Ko, W-C., Yu, C. J., Chen, Y. H. & Hsueh, P. R., 2018 Aug 1, In : Journal of Clinical Microbiology. 56, 8, e00427-18.

Research output: Contribution to journalArticle

Latent Tuberculosis
Long-Term Care
Gold
Taiwan
Interferon-gamma Release Tests
1 Citation (Scopus)

RIOK-1 is a suppressor of the p38 MAPK innate immune pathway in Caenorhabditis elegans

Chen, Y. W., Ko, W-C., Chen, C-S. & Chen, P-L., 2018 Apr 17, In : Frontiers in Immunology. 9, APR, 774.

Research output: Contribution to journalArticle

Caenorhabditis elegans
p38 Mitogen-Activated Protein Kinases
Infection
Genetic Epistasis
Aeromonas
1 Citation (Scopus)

Salvage therapy with intravenous fosfomycin plus ceftriaxone for necrotizing fasciitis caused by penicillin-nonsusceptible Streptococcus pneumoniae

Zhang, C. C., Weng, T. C., Su, B. A., Lai, C. C., Chuang, Y. C., Ko, W-C. & Tang, H. J., 2018 Aug 1, In : Journal of Microbiology, Immunology and Infection. 51, 4, p. 573-574 2 p.

Research output: Contribution to journalLetter

Fosfomycin
Necrotizing Fasciitis
Salvage Therapy
Ceftriaxone
Streptococcus pneumoniae

The ATP-P2X 7 signaling axis is an essential sentinel for intracellular Clostridium difficile pathogen-induced inflammasome activation

Liu, Y. H., Chang, Y. C., Chen, L. K., Su, P. A., Ko, W-C., Tsai, Y-S., Chen, Y. H., Lai, H. C., Wu, C. Y., Hung, Y. P. & Tsai, P-J., 2018 Mar 16, In : Frontiers in Cellular and Infection Microbiology. 8, MAR, 84.

Research output: Contribution to journalArticle

Inflammasomes
Clostridium difficile
Adenosine Triphosphate
Clostridium Infections
Caspase 1

Thiazolidinediones and reduced risk of incident bacterial abscess in adults with type 2 diabetes: A population-based cohort study

Wang, J-L., Dong, Y. H., Ko, W-C., Chang, C. H., Wu, L. C., Chuang, L. M. & Chen, P. C., 2018 Dec 1, In : Diabetes, Obesity and Metabolism. 20, 12, p. 2811-2820 10 p.

Research output: Contribution to journalArticle

Thiazolidinediones
Abscess
Type 2 Diabetes Mellitus
Cohort Studies
Population

Two fatal cases of Aeromonas dhakensis bacteremia and necrotizing fasciitis in severe dengue patients

Chang, H. L., Chen, P-L., Lin, S. Y., Chen, T. C., Chang, K., Ko, W-C., Lu, P. L. & Chen, Y. H., 2018 Oct 1, In : Journal of Microbiology, Immunology and Infection. 51, 5, p. 692-694 3 p.

Research output: Contribution to journalLetter

Severe Dengue
Necrotizing Fasciitis
Aeromonas
Bacteremia

檢測困難梭狀桿菌核醣分型027之序列、技術平台及其方法

Tsai, P-J., 蔡博仰, 洪元斌 & Ko, W-C., 2018, Patent No. ZL 2014 1 0494105.7

Research output: Patent

2017
6 Citations (Scopus)
Severe Dengue
Partial Thromboplastin Time
Intensive Care Units
Dengue Virus
Cohort Studies
5 Citations (Scopus)

A disease model of muscle necrosis caused by aeromonas dhakensis infection in caenorhabditis elegans

Chen, P-L., Chen, Y. W., Ou, C. C., Lee, T-M., Wu, C. J., Ko, W-C. & Chen, C-S., 2017 Jan 4, In : Frontiers in Microbiology. 7, JAN, 2058.

Research output: Contribution to journalArticle

Aeromonas
Caenorhabditis elegans
Necrosis
Muscles
RNA Interference