• 2076 Citations
  • 23 h-Index
19972020
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Research Output 1997 2019

  • 2076 Citations
  • 23 h-Index
  • 63 Article
  • 5 Review article
  • 1 Letter
2019

Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis

Yen, C. J., Yang, S. T., Chen, R. Y., Huang, W., Chayama, K., Lee, M. H., Yang, S. J., Lai, H. S., Yen, H. Y., Hsiao, Y. W., Wang, J. M., Lin, Y. J. & Hung, L. Y., 2019 Jun 6, In : Journal of biomedical science. 26, 1, 44.

Research output: Contribution to journalArticle

Open Access
Proteins
Hepatocellular Carcinoma
Viruses
Hepatitis B virus
Cyclic AMP Response Element-Binding Protein
2018

Ground glass hepatocytes provide targets for therapy or prevention of hepatitis B virus-related hepatocellular carcinoma

Chang, H., Tsai, H., Teng, C., Hui-ching Wang, L., Huang, W. & Su, I., 2018 Mar 1, In : AIMS Medical Science. 5, 2, p. 90-101

Research output: Contribution to journalArticle

5 Citations (Scopus)

Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection

Yen, C. J., Ai, Y. L., Tsai, H. W., Chan, S. H., Yen, C. S., Cheng, K. H., Lee, Y. P., Kao, C. W., Wang, Y. C., Chen, Y. L., Lin, C. H., Liu, T., Tsai, H. P., Wang, J. R., Su, I. J. & Huang, W., 2018 Sep, In : Hepatology. 68, 3, p. 815-826 12 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Hepatocellular Carcinoma
Biomarkers
Recurrence
Surface Antigens

Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection

Yen, C., Ai, Y., Tsai, H., Chan, S., Yen, C., Cheng, K., Lee, Y., Kao, C., Wang, Y., Chen, Y., Lin, C., Liu, T., Tsai, H., Wang, J., Su, I. & Huang, W., 2018 Sep 1, In : Hepatology. 68, 3, p. 815-826

Research output: Contribution to journalArticle

3 Citations (Scopus)

NEK2 promotes hepatoma metastasis and serves as biomarker for high recurrence risk after hepatic resection

Chang, Y. Y., Yen, C-J., Chan, S-H., Chou, Y. W., Lee, Y. P., Bao, C. Y., Huang, C. J. & Huang, W-Y., 2018 Sep 1, In : Annals of Hepatology. 17, 5, p. 843-856 14 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Biomarkers
Neoplasm Metastasis
Recurrence
Liver

NEK2 Promotes Hepatoma Metastasis and Serves as Biomarker for High Recurrence Risk after Hepatic Resection

Chang, Y., Yen, C., Chan, S., Chou, Y., Lee, Y., Bao, C., Huang, C. & Huang, W., 2018 Aug 24, In : Annals of Hepatology. 17, 5, p. 843-856

Research output: Contribution to journalArticle

2016
12 Citations (Scopus)

A biphasic response pattern of lipid metabolomics in the stage progression of hepatitis B virus X tumorigenesis

Teng, C. F., Hsieh, W. C., Yang, C. W., Su, H. M., Tsai, T. F., Sung, W. C., Huang, W-Y. & Su, I. J., 2016 Jan 1, In : Molecular Carcinogenesis. 55, 1, p. 105-114 10 p.

Research output: Contribution to journalArticle

Metabolomics
Hepatitis B virus
Carcinogenesis
Lipids
1-Acylglycerol-3-Phosphate O-Acyltransferase
10 Citations (Scopus)

Hepatitis B virus preS2-mutant large surface antigen activates store-operated calcium entry and promotes chromosome instability

Yen, T. T. C., Yang, A., Chiu, W-T., Li, T. N., Wang, L. H., Wu, Y. H., Wang, H. C., Chen, L., Wang, W. C., Huang, W-Y., Chang, C. W., Chang, M. D. T., Shen, M-R., Su, I. J. & Wang, L. H. C., 2016 Apr 26, In : Oncotarget. 7, 17, p. 23346-23360 15 p.

Research output: Contribution to journalArticle

Chromosomal Instability
Surface Antigens
Hepatitis B virus
Calcium
Endoplasmic Reticulum
7 Citations (Scopus)
Chronic Hepatitis B
Antiviral Agents
Glass
Hepatocytes
Hepatocellular Carcinoma
5 Citations (Scopus)

RON nuclear translocation under hypoxia potentiates chemoresistance to DNA double-strand break-inducing anticancer drugs

Chang, H. Y., Chang, T. C., Huang, W-Y., Lee, C-T., Yen, C-J., Tsai, Y-S., Tzai, T. S., Chen, S-H. & Chow, N-H., 2016 Feb 1, In : Molecular Cancer Therapeutics. 15, 2, p. 276-286 11 p.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Pharmaceutical Preparations
DNA End-Joining Repair
DNA-Activated Protein Kinase
Epirubicin
2015
12 Citations (Scopus)

Hepatitis B virus pre-S2 mutant induces aerobic glycolysis through mammalian target of rapamycin signal cascade

Teng, C. F., Hsieh, W. C., Wu, H. C., Lin, Y. J., Tsai, H. W., Huang, W. & Su, I. J., 2015 Apr 24, In : PloS one. 10, 4, e0122373.

Research output: Contribution to journalArticle

Hepatitis B virus
glycolysis
Glycolysis
Sirolimus
Viruses
16 Citations (Scopus)

Hepatitis B virus pre-S2 mutant large surface protein inhibits DNA double-strand break repair and leads to genome instability in hepatocarcinogenesis

Hsieh, Y. H., Chang, Y. Y., Su, I. J., Yen, C-J., Liu, Y. R., Liu, R. J., Hsieh, W. C., Tsai, H-W., Wang, L. H. C. & Huang, W-Y., 2015 Jul 1, In : Journal of Pathology. 236, 3, p. 337-347 11 p.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Genomic Instability
Hepatitis B virus
Membrane Proteins
Karyopherins
2014
2 Citations (Scopus)

Pathogenesis of virus-associated human cancers: Epstein-Barr virus and hepatitis B virus as two examples

Chang, K-C., Chang, Y., Wang, L. H. C., Tsai, H-W., Huang, W-Y. & Su, I. J., 2014 Jan 1, In : Journal of the Formosan Medical Association. 113, 9, p. 581-590 10 p.

Research output: Contribution to journalReview article

Human Herpesvirus 4
Hodgkin Disease
Hepatitis B virus
Viruses
Endoplasmic Reticulum Stress
32 Citations (Scopus)

The emerging role of hepatitis B virus Pre-S2 deletion mutant proteins in HBV tumorigenesis

Su, I. J., Wang, L. H. C., Hsieh, W. C., Wu, H. C., Teng, C. F., Tsai, H-W. & Huang, W-Y., 2014 Jan 1, In : Journal of biomedical science. 21, 1, 98.

Research output: Contribution to journalReview article

Mutant Proteins
Endoplasmic Reticulum Stress
Viruses
Hepatitis B virus
Carcinogenesis
5 Citations (Scopus)

Verification of wild-type EGFR status in non-small cell lung carcinomas using a mutant-enriched PCR on selected cases

Chen, Y. L., Lu, C-C., Yang, S. C., Su, W-P., Lin, Y. L., Chen, W. L., Huang, W-Y., Su, W-C., Chow, N-H. & Ho, C-L., 2014 Jan 1, In : Journal of Molecular Diagnostics. 16, 5, p. 486-494 9 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Peptide Nucleic Acids
Polymerase Chain Reaction
Mutation
DNA
2013
16 Citations (Scopus)

Essential role of β-human 8-oxoguanine DNA glycosylase 1 in mitochondrial oxidative DNA repair

Su, Y. H., Lee, Y. L., Chen, S. F., Lee, Y. P., Hsieh, Y. H., Tsai, J. H., Hsu, J. L., Tian, W. T. & Huang, W-Y., 2013 Jan 1, In : Environmental and Molecular Mutagenesis. 54, 1, p. 54-64 11 p.

Research output: Contribution to journalArticle

DNA Glycosylases
Mitochondrial DNA
DNA Repair
Mitochondrial Membranes
Electron Transport Complex I
16 Citations (Scopus)

Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis b virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients

Hsieh, Y. H., Su, I. J., Yen, C. J., Tsai, T. F., Tsai, H. W., Tsai, H. N., Huang, Y. J., Chen, Y. Y., Ai, Y. L., Kao, L. Y., Hsieh, W. C., Wu, H. C. & Huang, W., 2013 Feb 1, In : Carcinogenesis. 34, 2, p. 475-485 11 p.

Research output: Contribution to journalArticle

Hepatitis Viruses
Histone Deacetylase Inhibitors
Oncogene Proteins
Chronic Hepatitis B
Hepatitis B virus
2 Citations (Scopus)

Zinc-dependent interaction between JAB1 and Pre-S2 mutant large surface antigen of hepatitis B virus and its implications for viral hepatocarcinogenesis

Hsu, J. L., Chuang, W-J., Su, I. J., Gui, W. J., Chang, Y. Y., Lee, Y. P., Ai, Y. L., Chuang, D. T. & Huang, W-Y., 2013 Dec 1, In : Journal of Virology. 87, 23, p. 12675-12684 10 p.

Research output: Contribution to journalArticle

Hepatitis B virus
surface antigens
Surface Antigens
binding proteins
Zinc
2012
38 Citations (Scopus)

Aberrant cyclin a expression and centrosome overduplication induced by hepatitis B virus pre-S2 mutants and its implication in hepatocarcinogenesis

Wang, L. H. C., Huang, W., Lai, M. D. & Su, I. J., 2012 Feb 8, In : Carcinogenesis. 33, 2, p. 466-472 7 p.

Research output: Contribution to journalArticle

Cyclin A
Centrosome
Cyclins
Hepatitis B virus
Endoplasmic Reticulum Stress
20 Citations (Scopus)

Crystal structure and DNA-binding mode of Klebsiella pneumoniae primosomal PriB protein

Huang, Y. H., Lo, Y. H., Huang, W-Y. & Huang, C. Y., 2012 Oct 1, In : Genes to Cells. 17, 10, p. 837-849 13 p.

Research output: Contribution to journalArticle

Klebsiella pneumoniae
Single-Stranded DNA
Proteins
Nucleic Acids
Databases
9 Citations (Scopus)

Human herpesvirus 8-associated lymphoma mimicking cutaneous anaplastic large T-cell lymphoma in a patient with human immunodeficiency virus infection

Li, M. F., Hsiao, C. H., Chen, Y. L., Huang, W-Y., Lee, Y. H., Huang, H. N. & Lien, H. C., 2012 Feb 1, In : Journal of Cutaneous Pathology. 39, 2, p. 274-278 5 p.

Research output: Contribution to journalArticle

Anaplastic Large-Cell Lymphoma
Human Herpesvirus 8
T-Cell Lymphoma
Virus Diseases
Primary Effusion Lymphoma
8 Citations (Scopus)

Tumorous proliferations of plasmacytoid dendritic cells and Langerhans cells associated with acute myeloid leukaemia

Song, H. L., Huang, W-Y., Chen, Y-P. & Chang, K-C., 2012 Nov 1, In : Histopathology. 61, 5, p. 974-983 10 p.

Research output: Contribution to journalArticle

Langerhans Cells
Acute Myeloid Leukemia
Dendritic Cells
Myeloproliferative Disorders
Leukemia, Myelomonocytic, Chronic
2011
38 Citations (Scopus)

A clustered ground-glass hepatocyte pattern represents a new prognostic marker for the recurrence of hepatocellular carcinoma after surgery

Tsai, H-W., Lin, Y-J., Lin, P. W., Wu, H. C., Hsu, K. H., Yen, C-J., Chan, S-H., Huang, W-Y. & Su, I. J., 2011 Jul 1, In : Cancer. 117, 13, p. 2951-2960 10 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Glass
Hepatocytes
Hepatocellular Carcinoma
Hepatitis B Surface Antigens
25 Citations (Scopus)

ACSL3 and GSK-3β are essential for lipid upregulation induced by endoplasmic reticulum stress in liver cells

Chang, Y. S., Tsai, C. T., Huangfu, C. A., Huang, W. Y., Lei, H. Y., Lin, C. F., Su, I. J., Chang, W. T., Wu, P. H., Chen, Y. T., Hung, J. H., Young, K. C. & Lai, M. D., 2011 Mar 1, In : Journal of Cellular Biochemistry. 112, 3, p. 881-893 13 p.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Endoplasmic Reticulum Stress
Liver
Up-Regulation
Lipids
22 Citations (Scopus)

Genomic instability caused by hepatitis B virus: Into the hepatoma inferno

Hsieh, Y. H., Hsu, J. L., Su, I. J. & Huang, W-Y., 2011 Jun 1, In : Frontiers in Bioscience. 16, 7, p. 2586-2597 12 p.

Research output: Contribution to journalArticle

Genomic Instability
Viruses
Hepatitis B virus
Hepatocellular Carcinoma
Chromosomal Instability
18 Citations (Scopus)

Induction of Bcl-2 expression by hepatitis B virus pre-S2 mutant large surface protein resistance to 5-fluorouracil treatment in Huh-7 cells

Hung, J. H., Teng, Y. N., WangLily, L. H. C., Su, I. J., Wang, C. C. C., Huang, W., Lee, K. H., Lu, K. Y. & Wang, L. H., 2011 Dec 22, In : PloS one. 6, 12, e28977.

Research output: Contribution to journalArticle

fluorouracil
Hepatitis B virus
surface proteins
Surface Antigens
surface antigens
38 Citations (Scopus)

Novel feedback inhibition of surface antigen synthesis by mammalian target of rapamycin (mTOR) signal and its implication for hepatitis B virus tumorigenesis and therapy

Teng, C. F., Wu, H. C., Tsai, H. W., Shiah, H. S., Huang, W. & Su, I. J., 2011 Oct 1, In : Hepatology. 54, 4, p. 1199-1207 9 p.

Research output: Contribution to journalArticle

Sirolimus
Surface Antigens
Hepatitis B virus
Carcinogenesis
Histone Deacetylase 1
2010
4 Citations (Scopus)

Agaricus blazei Murill ameliorates myocardial ischemia-reperfusion injury

Huang, C. H., Tsai, H. N., Peng, R. H., Hsieh, Y. H., Chuang, W-J., Hsu, G. C., Huang, W-Y. & Chen, W. J., 2010 Dec 1, In : Acta Cardiologica Sinica. 26, 4, p. 235-241 7 p.

Research output: Contribution to journalArticle

Agaricus
Myocardial Reperfusion Injury
Reperfusion Injury
Myocardial Ischemia
Myocardial Reperfusion
6 Citations (Scopus)

Beta interferon plus gamma interferon efficiently reduces acyclovir-resistant herpes simplex virus infection in mice in a T-cell-independent manner

Huang, W. Y., Su, Y. H., Yao, H. W., Ling, P., Tung, Y. Y., Chen, S. H., Wang, X. & Chen, S. H., 2010 Feb 23, In : Journal of General Virology. 91, 3, p. 591-598 8 p.

Research output: Contribution to journalArticle

Acyclovir
Interferon-beta
Virus Diseases
Simplexvirus
Interferons
23 Citations (Scopus)

BIOMED-2 protocols to detect clonal immunoglobulin and T-cell receptor gene rearrangements in B- and T-cell lymphomas in southern Taiwan

Chen, Y. L., Su, I. J., Cheng, H. Y., Chang, K-C., Lu, C-C., Chow, N-H., Ho, C-L. & Huang, W-Y., 2010 Apr 1, In : Leukemia and Lymphoma. 51, 4, p. 650-655 6 p.

Research output: Contribution to journalArticle

T-Lymphocyte Gene Rearrangement
T-Cell Receptor Genes
T-Cell Lymphoma
B-Cell Lymphoma
Taiwan
7 Citations (Scopus)

Hepatitis B virus surface antigen interacts with acid alpha-glucosidase and alters glycogen metabolism

Hung, J. H., Yan, C. W., Su, I. J., Wang, H. C., Lei, H. Y., Lin, W. C., Chang, W. T., Huang, W., Lu, T. J. & Lai, M. D., 2010 Jun 1, In : Hepatology Research. 40, 6, p. 633-640 8 p.

Research output: Contribution to journalArticle

Glucosidases
alpha-Glucosidases
Hepatitis B Surface Antigens
Glycogen
Hepatitis B virus
2009
17 Citations (Scopus)

A pre-S gene chip to detect pre-S deletions in hepatitis B virus large surface antigen as a predictive marker for hepatoma risk in chronic hepatitis B virus carriers

Shen, F. C., Su, I. J., Wu, H. C., Hsieh, Y. H., Yao, W-J., Young, K-C., Chang, T. C., Hsieh, H. C., Tsai, H. N. & Huang, W-Y., 2009 Oct 12, In : Journal of biomedical science. 16, 1, 84.

Research output: Contribution to journalArticle

Chronic Hepatitis B
Surface Antigens
Oligonucleotide Array Sequence Analysis
Viruses
Hepatitis B virus
81 Citations (Scopus)

Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis

Yang, J. C., Teng, C. F., Wu, H. C., Tsai, H-W., Chuang, H. C., Tsai, T. F., Hsu, Y. H., Huang, W-Y., Wu, L-W. & Su, I. J., 2009 Jun 1, In : Hepatology. 49, 6, p. 1962-1971 10 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Vascular Endothelial Growth Factor A
Glass
Hepatocytes
Hepatocellular Carcinoma
13 Citations (Scopus)

Solution structure and backbone dynamics of streptopain: Insight into diverse substrate specificity

Wang, C. C., Houng, H. C., Chen, C. L., Wang, P. J., Kuo, C. F., Lin, Y-S., Wu, J. J., Lin, M. T., Liu, C-C., Huang, W-Y. & Chuang, W-J., 2009 Apr 17, In : Journal of Biological Chemistry. 284, 16, p. 10957-10967 11 p.

Research output: Contribution to journalArticle

streptopain
Substrate Specificity
Substrates
X-Rays
X rays
2008
81 Citations (Scopus)

Ground glass hepatocytes contain pre-S mutants and represent preneoplastic lesions in chronic hepatitis B virus infection

Su, I. J., Wang, H. C., Wu, H. C. & Huang, W. Y., 2008 Aug, In : Journal of Gastroenterology and Hepatology (Australia). 23, 8 PART1, p. 1169-1174 6 p.

Research output: Contribution to journalReview article

Chronic Hepatitis B
Virus Diseases
Hepatitis B virus
Glass
Hepatocytes
7 Citations (Scopus)

Reduced expression of von Hippel-Lindau gene in subjects exposed to polychlorinated biphenyls and dibenzofurans

Tsai, P. C., Wang, Y-J., Tsai, J. H., Guo, Y. L., Ueng, T. H., Liu, H-S. & Huang, W-Y., 2008 Oct 1, In : Environmental Research. 108, 2, p. 247-251 5 p.

Research output: Contribution to journalArticle

Malformed Nails
Polychlorinated Biphenyls
PCDF
Nails
PCB
4 Citations (Scopus)

Streptococcal pyrogenic exotoxin B cleaves human S-adenosylhomocysteine hydrolase and induces hypermethioninemia

Hsu, J. F., Chuang, W-J., Shiesh, S-C., Lin, Y-S., Liu, C-C., Wang, C. C., Fu, T-F., Tsai, J. H., Tsai, W. L., Huang, Y. J., Hsieh, Y. H., Wu, J. J., Lin, M. T. & Huang, W-Y., 2008 Aug 1, In : Journal of Infectious Diseases. 198, 3, p. 367-374 8 p.

Research output: Contribution to journalArticle

Adenosylhomocysteinase
Cysteine Proteases
Impetigo
Myositis
Pharyngitis
17 Citations (Scopus)
p38 Mitogen-Activated Protein Kinases
Virus Replication
Hepatitis B virus
Antiviral Agents
Hepatocellular Carcinoma
2007
26 Citations (Scopus)

Differential endoplasmic reticulum stress signaling pathways mediated by iNOS

Hsieh, Y. H., Su, I. J., Lei, H. Y., Lai, M-D., Chang, W. W. & Huang, W-Y., 2007 Aug 3, In : Biochemical and Biophysical Research Communications. 359, 3, p. 643-648 6 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Oxidative stress
Nitric Oxide Synthase Type II
Oxidative Stress
Endoplasmic Reticulum
56 Citations (Scopus)

Hepatitis B virus pre-S2 mutant surface antigen induces degradation of cyclin-dependent kinase inhibitor p27Kip1 through c-Jun activation domain-binding protein 1

Hsieh, Y. H., Su, I. J., Wang, H. C., Tsai, J. H., Huang, Y. J., Chang, W. W., Lai, M. D., Lei, H. Y. & Huang, W., 2007 Oct 1, In : Molecular Cancer Research. 5, 10, p. 1063-1072 10 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinases
Surface Antigens
Hepatitis B virus
Carrier Proteins
Cyclin-Dependent Kinase 2
46 Citations (Scopus)

Increased liver and lupus mortalities in 24-year follow-up of the Taiwanese people highly exposed to polychlorinated biphenyls and dibenzofurans

Tsai, P. C., Ko, Y. C., Huang, W-Y., Liu, H-S. & Guo, Y. L., 2007 Mar 15, In : Science of the Total Environment. 374, 2-3, p. 216-222 7 p.

Research output: Contribution to journalArticle

Polychlorinated Biphenyls
PCDF
Polychlorinated biphenyls
Liver
PCB
2006
9 Citations (Scopus)

Competition and complementation between thymidine kinase-negative and wild-type herpes simplex virus during co-infection of mouse trigeminal ganglia

Chen, S. H., Lin, Y. W., Griffiths, A., Huang, W-Y. & Chen, S., 2006 Dec 1, In : Journal of General Virology. 87, 12, p. 3495-3502 8 p.

Research output: Contribution to journalArticle

Trigeminal Ganglion
Thymidine Kinase
Simplexvirus
Coinfection
Viruses
23 Citations (Scopus)

Efficient reactivation of latent herpes simplex virus from mouse central nervous system tissues

Chen, S. H., Yao, H. W., Huang, W-Y., Hsu, K-S., Lei, H. Y., Shiau, A-L. & Chen, S., 2006 Dec 1, In : Journal of Virology. 80, 24, p. 12387-12392 6 p.

Research output: Contribution to journalArticle

herpes simplex
Nerve Tissue
Simplexvirus
central nervous system
Central Nervous System
20 Citations (Scopus)

Genetic polymorphisms in CYP1A1 and GSTM1 predispose humans to PCBs/PCDFs-induced skin lesions

Tsai, P. C., Huang, W-Y., Lee, Y. C., Chan, S-H. & Guo, Y. L., 2006 May 1, In : Chemosphere. 63, 8, p. 1410-1418 9 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP1A1
Polychlorinated Biphenyls
dibenzofuran
Genetic Polymorphisms
Polymorphism
47 Citations (Scopus)

Glutathione S-transferase polymorphisms associated with risk of breast cancer in southern Taiwan

Chang, T. W., Wang, S. M., Guo, Y. L. L., Tsai, P. C., Huang, C. J. & Huang, W., 2006 Dec, In : Breast. 15, 6, p. 754-761 8 p.

Research output: Contribution to journalArticle

Glutathione Transferase
Taiwan
Breast Neoplasms
Catechol Estrogens
Recombinational DNA Repair
164 Citations (Scopus)

Hepatitis B Virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis

Wang, H. C., Huang, W-Y., Lai, M-D. & Su, I. J., 2006 Aug 1, In : Cancer Science. 97, 8, p. 683-688 6 p.

Research output: Contribution to journalReview article

Endoplasmic Reticulum Stress
Hepatitis B virus
Hepatocellular Carcinoma
Hepatocytes
Cyclin A
30 Citations (Scopus)

Preparation of amino-acid-type selective isotope labeling of protein expressed in Pichia pastoris

Chen, C. Y., Cheng, C. H., Chen, Y. C., Lee, J. C., Chou, S. H., Huang, W. & Chuang, W. J., 2006 Jan 1, In : Proteins: Structure, Function and Genetics. 62, 1, p. 279-287 9 p.

Research output: Contribution to journalArticle

Isotope Labeling
Pichia
Isotopes
Labeling
Amino Acids
2005
100 Citations (Scopus)

Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes

Wang, H. C., Chang, W. T., Chang, W. W., Wu, H. C., Huang, W., Lei, H. Y., Lai, M. D., Fausto, N. & Su, I. J., 2005 Apr 1, In : Hepatology. 41, 4, p. 761-770 10 p.

Research output: Contribution to journalArticle

Cyclin A
Hepatitis B virus
Hepatocytes
Up-Regulation
Endoplasmic Reticulum Stress
10 Citations (Scopus)

HHR23A, a human homolog of Saccharomyces cerevisiae Rad23, regulates xeroderma pigmentosum C protein and is required for nucleotide excision repair

Hsieh, H. C., Hsieh, Y. H., Huang, Y. H., Shen, F. C., Tsai, H. N., Tsai, J. H., Lai, Y. T., Wang, Y. T., Chuang, W-J. & Huang, W-Y., 2005 Sep 16, In : Biochemical and Biophysical Research Communications. 335, 1, p. 181-187 7 p.

Research output: Contribution to journalArticle

Xeroderma Pigmentosum
Protein C
DNA Repair
Yeast
Saccharomyces cerevisiae
21 Citations (Scopus)

Therapeutic inhibition of hepatitis B virus surface antigen expression by RNA interference

Cheng, T. L., Chang, W. W., Su, I. J., Lai, M-D., Huang, W-Y., Lei, H. Y. & Chang, W-T., 2005 Oct 28, In : Biochemical and Biophysical Research Communications. 336, 3, p. 820-830 11 p.

Research output: Contribution to journalArticle

Surface Antigens
Hepatitis B Surface Antigens
RNA Interference
Viruses
Hepatitis B virus