Woei-Jer Chuang &ndash; Research Output

2017

Effects of the RGD loop and C-terminus of rhodostomin on regulating integrin αIIbβ3 recognition

Chang, Y. T., Shiu, J. H., Huang, C. H., Chen, Y. C., Chen, C. Y., Chang, Y. S. & Chuang, W-J., 2017 Apr 1, In : PLoS ONE. 12, 4, e0175321.

Research output: Contribution to journal › Article

integrins

Integrins

Platelets

Disintegrins

mutants

4 Citations (Scopus)

Inhibition of osteoporosis by the αvβ3 integrin antagonist of rhodostomin variants

Lin, T. H., Yang, R. S., Tu, H. J., Liou, H. C., Lin, Y. M., Chuang, W-J. & Fu, W. M., 2017 Jan 1, In : European Journal of Pharmacology. 804, p. 94-101 8 p.

Research output: Contribution to journal › Article

Osteoclasts

Integrins

Osteoporosis

Bone Resorption

Osteogenesis

2016

Epidemiology analysis of streptococcus pyogenes in a hospital in Southern Taiwan by use of the updated emm cluster typing system

Chiang-Ni, C., Zheng, P. X., Wang, S-Y., Tsai, P-J., Chuang, W-J., Lin, Y-S., Liu, C-C. & Wu, J. J., 2016 Jan 1, In : Journal of Clinical Microbiology. 54, 1, p. 157-162 6 p.

Research output: Contribution to journal › Article

Streptococcus pyogenes

Streptococcus

Taiwan

Epidemiology

Molecular Typing

3 Citations (Scopus)

Improved antithrombotic activity and diminished bleeding side effect of a PEGylated αiIbβ3 antagonist, disintegrin

Hsu, C. C., Chuang, W-J., Chung, C. H., Chang, C. H., Peng, H. C. & Huang, T. F., 2016 Jul 1, In : Thrombosis Research. 143, p. 3-10 8 p.

Research output: Contribution to journal › Article

Disintegrins

Hemorrhage

Half-Life

Platelet Aggregation

rhodostomin

Predicting the redox state and secondary structure of cysteine residues using multi-dimensional classification analysis of NMR chemical shifts

Wang, C. C., Lai, W. C. & Chuang, W-J., 2016 Sep 1, In : Journal of Biomolecular NMR. 66, 1, p. 55-68 14 p.

Research output: Contribution to journal › Article

Chemical shift

Oxidation-Reduction

Cysteine

Magnetic Resonance Spectroscopy

Nuclear magnetic resonance

5 Citations (Scopus)

Snake Venom Disintegrin Inhibits the Activation of Toll-Like Receptors and Alleviates Sepsis through Integrin alphaVbeta3 Blockade

Hsu, C. C., Chuang, W-J., Chung, C. H., Chang, C. H., Peng, H. C. & Huang, T. F., 2016 Mar 18, In : Scientific reports. 6, 23387.

Research output: Contribution to journal › Article

Integrin alphaVbeta3

Disintegrins

Snake Venoms

Toll-Like Receptors

Sepsis

Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage

Chen, C. L., Wu, Y. Y., Lin, C. F., Kuo, C. F., Han, C. L., Wang, S-Y., Chuang, W-J., Chen, C. Y., Wu, J. J., Tsai, P-J., Liu, C-C. & Lin, Y-S., 2016 May 16, In : Scientific reports. 6, 26026.

Research output: Contribution to journal › Article

Protein S

Macrophages

streptopain

Streptococcus

Phagocytosis

2015

1 Citation (Scopus)

Clustered regularly interspaced short palindromic repeats are emm type-specific in highly prevalent group A streptococci

Zheng, P. X., Chan, Y. C., Chiou, C. S., Chiang-Ni, C., Wang, S-Y., Tsai, P-J., Chuang, W-J., Lin, Y-S., Liu, C-C. & Wu, J. J., 2015 Dec 1, In : PLoS ONE. 10, 12, e0145223.

Research output: Contribution to journal › Article

Clustered Regularly Interspaced Short Palindromic Repeats

Streptococcus

molecular epidemiology

loci

nucleic acids

14 Citations (Scopus)

Role of spinal CXCL1 (GROα) in opioid tolerance a human-to-rodent translational study

Lin, C. P., Kang, K. H., Lin, T. H., Wu, M. Y., Liou, H. C., Chuang, W-J., Sun, W. Z. & Fu, W. M., 2015 Mar 4, In : Anesthesiology. 122, 3, p. 666-676 11 p.

Research output: Contribution to journal › Article

Opioid Analgesics

Rodentia

Morphine

Cerebrospinal Fluid

Chemokines

2014

3 Citations (Scopus)

Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus

Zheng, P. X., Chiang-Ni, C., Wang, S-Y., Tsai, P-J., Kuo, C. F., Chuang, W-J., Lin, Y-S., Liu, C-C. & Wu, J. J., 2014 Jan 1, In : Clinical Microbiology and Infection. 20, 6, p. 516-523 8 p.

Research output: Contribution to journal › Article

Clustered Regularly Interspaced Short Palindromic Repeats

Erythromycin

Streptococcus

Nucleic Acids

Streptococcus pyogenes

9 Citations (Scopus)

Distinct structural features of the peroxide response regulator from group A streptococcus drive DNA binding

Lin, C. S. H., Chao, S. Y., Hammel, M., Nix, J. C., Tseng, H. L., Tsou, C. C., Fei, C. H., Chiou, H. S., Jeng, U. S., Lin, Y-S., Chuang, W-J., Wu, J. J. & Wang, S-Y., 2014 Feb 21, In : PloS one. 9, 2, e89027.

Research output: Contribution to journal › Article

Streptococcus

Peroxides

peroxides

DNA

X ray scattering

5 Citations (Scopus)

Invasive hypermucoid variant of group A Streptococcus is defective in growth and susceptible to DNA-damaging treatments

Chiang-Ni, C., Zheng, P. X., Wang, S-Y., Tsai, P-J., Kuo, C. F., Chuang, W-J., Lin, Y-S., Liu, C-C. & Wu, J. J., 2014 Jan 1, In : Pathogens and Disease. 70, 2, p. 194-201 8 p.

Research output: Contribution to journal › Article

Streptococcus

Capsules

DNA

Growth

Virulence

2 Citations (Scopus)

Type i and II β-turns prediction using NMR chemical shifts

Wang, C. C., Lai, W. C. & Chuang, W-J., 2014 Jan 1, In : Journal of Biomolecular NMR. 59, 3, p. 175-184 10 p.

Research output: Contribution to journal › Article

Chemical shift

Magnetic Resonance Spectroscopy

Nuclear magnetic resonance

Secondary Protein Structure

Cluster Analysis

2013

11 Citations (Scopus)

Complete genome sequence of emm1 Streptococcus pyogenes A20, a strain with an intact two-component system, CovRS, isolated from a patient with necrotizing fasciitis

Zheng, P. X., Chung, K. T., Chiang-Ni, C., Wang, S-Y., Tsai, P-J., Chuang, W-J., Lin, Y-S., Liu, C-C. & Wu, J. J., 2013 Jan 1, In : Genome Announcements. 1, 1, e00149-12.

Research output: Contribution to journal › Article

Necrotizing Fasciitis

Streptococcus pyogenes

Pandemics

Genome

24 Citations (Scopus)

Kallistatin modulates immune cells and confers anti-inflammatory response to protect mice from group a streptococcal infection

Lu, S. L., Tsai, C. Y., Luo, Y. H., Kuo, C. F., Lin, W-C., Chang, Y-T., Wu, J. J., Chuang, W-J., Liu, C-C., Chao, L., Chao, J. & Lin, Y-S., 2013 Nov 1, In : Antimicrobial Agents and Chemotherapy. 57, 11, p. 5366-5372 7 p.

Research output: Contribution to journal › Article

Streptococcal Infections

Anti-Inflammatory Agents

Streptococcus

Infection

kallistatin

10 Citations (Scopus)

Peroxide responsive regulator PerR of group A streptococcus is required for the expression of phage-associated DNase Sda1 under oxidative stress

Wang, C. H., Chiang-Ni, C., Kuo, H. T., Zheng, P. X., Tsou, C. C., Wang, S-Y., Tsai, P-J., Chuang, W-J., Lin, Y-S., Liu, C-C. & Wu, J. J., 2013 Dec 3, In : PLoS ONE. 8, 12, e81882.

Research output: Contribution to journal › Article

deoxyribonucleases

Bacteriophages

Oxidative stress

Deoxyribonucleases

Streptococcus

24 Citations (Scopus)

Upregulation of drug transporter expression by osteopontin in prostate cancer cellss

Hsieh, I. S., Huang, W. H., Liou, H. C., Chuang, W-J., Yang, R. S. & Fu, W. M., 2013 May 1, In : Molecular Pharmacology. 83, 5, p. 968-977 10 p.

Research output: Contribution to journal › Article

Osteopontin

Prostatic Neoplasms

Up-Regulation

Daunorubicin

Pharmaceutical Preparations

2 Citations (Scopus)

Zinc-dependent interaction between JAB1 and Pre-S₂ mutant large surface antigen of hepatitis B virus and its implications for viral hepatocarcinogenesis

Hsu, J. L., Chuang, W-J., Su, I. J., Gui, W. J., Chang, Y. Y., Lee, Y. P., Ai, Y. L., Chuang, D. T. & Huang, W-Y., 2013 Dec 1, In : Journal of Virology. 87, 23, p. 12675-12684 10 p.

Research output: Contribution to journal › Article

Hepatitis B virus

surface antigens

Surface Antigens

binding proteins

Zinc

2012

3 Citations (Scopus)

Dynamics and functional differences between dendroaspin and rhodostomin: Insights into protein scaffolds in integrin recognition

Cheng, C. H., Chen, Y. C., Shiu, J. H., Chang, Y. T., Chang, Y. S., Huang, C. H., Chen, C. Y. & Chuang, W-J., 2012 Dec 1, In : Protein Science. 21, 12, p. 1872-1884 13 p.

Research output: Contribution to journal › Article

Scaffolds

Integrins

Proteins

mambin

rhodostomin

9 Citations (Scopus)

Effect of p to a mutation of the n-terminal residue adjacent to the rgd motif on rhodostomin: Importance of dynamics in integrin recognition

Shiu, J. H., Chen, C. Y., Chen, Y. C., Chang, Y. T., Chang, Y. S., Huang, C. H. & Chuang, W-J., 2012 Jan 4, In : PLoS ONE. 7, 1, e28833.

Research output: Contribution to journal › Article

integrins

Integrins

mutation

mutants

Mutation

9 Citations (Scopus)

Environmental pH changes, but not the LuxS signalling pathway, regulate SpeB expression in M1 group A streptococci

Chiang-Ni, C., Zheng, P. X., Tsai, P-J., Chuang, W-J., Lin, Y-S., Liu, C-C. & Wu, J. J., 2012 Jan 1, In : Journal of Medical Microbiology. 61, 1, p. 16-22 7 p.

Research output: Contribution to journal › Article

Streptococcus

Quorum Sensing

Cysteine Proteases

Virulence Factors

Mutation

6 Citations (Scopus)

Expression in Pichia pastoris and characterization of echistatin, an RGD-containing short disintegrin

Chen, Y. C., Cheng, C. H., Shiu, J. H., Chang, Y. T., Chang, Y. S., Huang, C. H., Lee, J-C. & Chuang, W-J., 2012 Dec 5, In : Toxicon. 60, 8, p. 1342-1348 7 p.

Research output: Contribution to journal › Article

Disintegrins

Pichia

Integrins

Platelets

Platelet Aggregation

8 Citations (Scopus)

Recombinant Expression of Margatoxin and Agitoxin-2 in Pichia pastoris: An Efficient Method for Production of K_V1.3 Channel Blockers

Anangi, R., Koshy, S., Huq, R., Beeton, C., Chuang, W-J. & King, G. F., 2012 Dec 29, In : PloS one. 7, 12, e52965.

Research output: Contribution to journal › Article

Pichia pastoris

Pichia

T-cells

toxins

Disulfides

2011

12 Citations (Scopus)

Emergence of uncommon emm types of Streptococcus pyogenes among adult patients in southern Taiwan

Chiang-Ni, C., Wu, A-B., Liu, C-C., Chen, K. T., Lin, Y-S., Chuang, W-J., Fang, H. Y. & Wu, J. J., 2011 Dec 1, In : Journal of Microbiology, Immunology and Infection. 44, 6, p. 424-429 6 p.

Research output: Contribution to journal › Article

Streptococcus pyogenes

Taiwan

Cellulitis

Infection

Population

7 Citations (Scopus)

Epitope mapping and structural analysis of the anti-Der p 1 monoclonal antibody: Insight into therapeutic potential

Dai, Y. C., Chuang, W-J., Chua, K. Y., Shieh, C-C. & Wang, J-Y., 2011 Jul 1, In : Journal of Molecular Medicine. 89, 7, p. 701-712 12 p.

Research output: Contribution to journal › Article

Epitope Mapping

Monoclonal Antibodies

Cysteine Proteases

Allergens

Immunoglobulin E

11 Citations (Scopus)

Improvements in endotoxemic syndromes using a disintegrin, rhodostomin, through integrin αvβ3-dependent pathway

Hsu, C. C., Chuang, W-J., Chang, C. H., Tseng, Y. L., Peng, H. C. & Huang, T. F., 2011 Mar 1, In : Journal of Thrombosis and Haemostasis. 9, 3, p. 593-602 10 p.

Research output: Contribution to journal › Article

Disintegrins

Integrins

Lipopolysaccharides

Phagocytes

Monocytes

16 Citations (Scopus)

Solution structure and backbone dynamics of the DNA-binding domain of FOXP1: Insight into its domain swapping and DNA binding

Chu, Y. P., Chang, C. H., Shiu, J. H., Chang, Y. T., Chen, C. Y. & Chuang, W-J., 2011 May 1, In : Protein Science. 20, 5, p. 908-924 17 p.

Research output: Contribution to journal › Article

Monomers

Dimers

DNA

Hinges

Forkhead Transcription Factors

7 Citations (Scopus)

The deficient cleavage of M protein-bound IgG by IdeS: Insight into the escape of Streptococcus pyogenes from antibody-mediated immunity

Su, Y. F., Chuang, W-J., Wang, S-M., Chen, W. Y., Chiang-Ni, C., Lin, Y-S., Wu, J. J. & Liu, C-C., 2011 Oct 1, In : Molecular Immunology. 49, 1-2, p. 134-142 9 p.

Research output: Contribution to journal › Article

Streptococcus pyogenes

Immunity

Immunoglobulin G

Antibodies

Enzymes

2010

4 Citations (Scopus)

Agaricus blazei Murill ameliorates myocardial ischemia-reperfusion injury

Huang, C. H., Tsai, H. N., Peng, R. H., Hsieh, Y. H., Chuang, W-J., Hsu, G. C., Huang, W-Y. & Chen, W. J., 2010 Dec 1, In : Acta Cardiologica Sinica. 26, 4, p. 235-241 7 p.

Research output: Contribution to journal › Article

Agaricus

Myocardial Reperfusion Injury

Reperfusion Injury

Myocardial Ischemia

Myocardial Reperfusion

13 Citations (Scopus)

Expression in Pichia pastoris and characterization of APETx2, a specific inhibitor of acid sensing ion channel 3

Anangi, R., Chen, C. C., Lin, Y. W., Cheng, Y. R., Cheng, C. H., Chen, Y. C., Chu, Y. P. & Chuang, W-J., 2010 Dec 1, In : Toxicon. 56, 8, p. 1388-1397 10 p.

Research output: Contribution to journal › Article

Acid Sensing Ion Channel Blockers

Pichia

Acid Sensing Ion Channels

Nuclear magnetic resonance

Neurology

15 Citations (Scopus)

Molecular mimicry between streptococcal pyrogenic exotoxin B and endothelial cells

Luo, Y. H., Chuang, W-J., Wu, J. J., Lin, M. T., Liu, C-C., Lin, P-Y., Roan, J-N., Wong, T-W., Chen, Y-L. & Lin, Y-S., 2010 Oct 1, In : Laboratory Investigation. 90, 10, p. 1492-1506 15 p.

Research output: Contribution to journal › Article

Molecular Mimicry

B-Lymphocytes

Endothelial Cells

Monoclonal Antibodies

Bovine Serum Albumin

20 Citations (Scopus)

Oxidative stress and metal ions regulate a ferritin-like gene, dpr, in Streptococcus pyogenes

Tsou, C. C., Chiang-Ni, C., Lin, Y-S., Chuang, W-J., Lin, M. T., Liu, C-C. & Wu, J. J., 2010 Apr 1, In : International Journal of Medical Microbiology. 300, 4, p. 259-264 6 p.

Research output: Contribution to journal › Article

Streptococcus pyogenes

Peroxides

Ferritins

Hydrogen Peroxide

Oxidative Stress

2009

12 Citations (Scopus)

Changing epidemiology of Streptococcus pyogenes emm types and associated invasive and noninvasive infections in southern Taiwan

Su, Y. F., Wang, S-M., Lin, Y. L., Chuang, W-J., Lin, Y-S., Wu, J. J., Lin, M. T. & Liu, C-C., 2009 Aug 1, In : Journal of Clinical Microbiology. 47, 8, p. 2658-2661 4 p.

Research output: Contribution to journal › Article

Streptococcus pyogenes

Taiwan

Epidemiology

Scarlet Fever

Pharyngitis

8 Citations (Scopus)

Effect of D to E mutation of the RGD motif in rhodostomin on its activity, structure, and dynamics: Importance of the interactions between the D residue and integrin

Chen, C. Y., Shiu, J. H., Hsieh, Y. H., Liu, Y. C., Chen, Y. C., Chen, Y. C., Jeng, W-Y., Tang, M-J., Lo, S. J. & Chuang, W-J., 2009 Sep 1, In : Proteins: Structure, Function and Bioinformatics. 76, 4, p. 808-821 14 p.

Research output: Contribution to journal › Article

Integrins

Mutation

Platelets

Platelet Aggregation

Hydrogen

12 Citations (Scopus)

emm1/sequence type 28 strains of group A streptococci that express covR at early stationary phase are associated with increased growth and earlier speB secretion

Chiang-Ni, C., Zheng, P. X., Ho, Y-R., Wu, H. M., Chuang, W-J., Lin, Y-S., Lin, M. T., Liu, C-C. & Wu, J. J., 2009 Oct 1, In : Journal of Clinical Microbiology. 47, 10, p. 3161-3169 9 p.

Research output: Contribution to journal › Article

Streptococcus

Growth

Necrotizing Fasciitis

Multilocus Sequence Typing

Streptococcus pyogenes

17 Citations (Scopus)

Procaspase 8 and bax are up-regulated by distinct pathways in streptococcal pyrogenic exotoxin B-induced apoptosis

Chang, C. W., Tsai, W. H., Chuang, W-J., Lin, Y-S., Wu, J. J., Liu, C-C., Tsai, P-J. & Lin, M. T., 2009 Nov 27, In : Journal of Biological Chemistry. 284, 48, p. 33195-33205 11 p.

Research output: Contribution to journal › Article

Caspase 8

Small Interfering RNA

Phosphorylation

Apoptosis

Tyrosine

13 Citations (Scopus)

Solution structure and backbone dynamics of streptopain: Insight into diverse substrate specificity

Wang, C. C., Houng, H. C., Chen, C. L., Wang, P. J., Kuo, C. F., Lin, Y-S., Wu, J. J., Lin, M. T., Liu, C-C., Huang, W-Y. & Chuang, W-J., 2009 Apr 17, In : Journal of Biological Chemistry. 284, 16, p. 10957-10967 11 p.

Research output: Contribution to journal › Article

streptopain

Substrate Specificity

Substrates

X-Rays

X rays

4 Citations (Scopus)

The IL-8 production by streptococcal pyrogenic exotoxin B

Chang, C. W., Wu, S. Y., Chuang, W-J., Lin, Y-S., Wu, S. Y., Liu, C-C., Tsai, P-J. & Lin, M. T., 2009 Nov 1, In : Experimental Biology and Medicine. 234, 11, p. 1316-1326 11 p.

Research output: Contribution to journal › Article

Caspase 8

Interleukin-8

Chemical activation

CD95 Antigens

Phosphorylation

2008

32 Citations (Scopus)

An iron-binding protein, Dpr, decreases hydrogen peroxide stress and protects Streptococcus pyogenes against multiple stresses

Tsou, C. C., Chiang-Ni, C., Lin, Y-S., Chuang, W-J., Lin, M. T., Liu, C-C. & Wu, J. J., 2008 Sep 1, In : Infection and Immunity. 76, 9, p. 4038-4045 8 p.

Research output: Contribution to journal › Article

Iron-Binding Proteins

Streptococcus pyogenes

Hydrogen Peroxide

Iron

Peroxides

30 Citations (Scopus)

Degradation of complement 3 by streptococcal pyrogenic exotoxin B inhibits complement activation and neutrophil opsonophagocytosis

Kuo, C. F., Lin, Y-S., Chuang, W-J., Wu, J. J. & Tsao, N., 2008 Mar 1, In : Infection and Immunity. 76, 3, p. 1163-1169 7 p.

Research output: Contribution to journal › Article

Complement C3

Complement Activation

Neutrophils

Serum

Zymosan

5 Citations (Scopus)

Group A streptococcal infection caused by emm1 strains among children in southern Taiwan

Lin, H. C., Wang, S-M., Lin, Y. L., Lin, Y-S., Wu, J. J., Chuang, W-J., Lin, M. T. & Liu, C-C., 2008 Dec 1, In : European Journal of Clinical Microbiology and Infectious Diseases. 27, 12, p. 1253-1256 4 p.

Research output: Contribution to journal › Article

Streptococcal Infections

Streptococcus

Taiwan

Molecular Epidemiology

Erythromycin

4 Citations (Scopus)

Streptococcal pyrogenic exotoxin B cleaves human S-adenosylhomocysteine hydrolase and induces hypermethioninemia

Hsu, J. F., Chuang, W-J., Shiesh, S-C., Lin, Y-S., Liu, C-C., Wang, C. C., Fu, T-F., Tsai, J. H., Tsai, W. L., Huang, Y. J., Hsieh, Y. H., Wu, J. J., Lin, M. T. & Huang, W-Y., 2008 Aug 1, In : Journal of Infectious Diseases. 198, 3, p. 367-374 8 p.

Research output: Contribution to journal › Article

Adenosylhomocysteinase

Cysteine Proteases

Impetigo

Myositis

Pharyngitis

14 Citations (Scopus)

Streptococcal pyrogenic exotoxin B-induced apoptosis in A549 cells is mediated through α_vβ₃ integrin and Fas

Tsai, W. H., Chang, C. W., Lin, Y-S., Chuang, W-J., Wu, J. J., Liu, C-C., Tsai, P-J. & Lin, M. T., 2008 Apr 1, In : Infection and Immunity. 76, 4, p. 1349-1357 9 p.

Research output: Contribution to journal › Article

Integrins

Apoptosis

Anti-Idiotypic Antibodies

A549 Cells

erythrogenic toxin

20 Citations (Scopus)

The severity of Streptococcus pyogenes infections in children is significantly associated with plasma levels of inflammatory cytokines

Wang, S-M., Lu, I. H., Lin, Y. L., Lin, Y-S., Wu, J. J., Chuang, W-J., Lin, M. T. & Liu, C-C., 2008 Jun 1, In : Diagnostic Microbiology and Infectious Disease. 61, 2, p. 165-169 5 p.

Research output: Contribution to journal › Article

Streptococcus pyogenes

Streptococcus

Cytokines

Interleukin-18

Interleukin-12

8 Citations (Scopus)

The transcriptional terminator sequences downstream of the covR gene terminate covR/S operon transcription to generate covR monocistronic transcripts in Streptococcus pyogenes

Chiang-Ni, C., Tsou, C. C., Lin, Y-S., Chuang, W-J., Lin, M. T., Liu, C-C. & Wu, J. J., 2008 Dec 31, In : Gene. 427, 1-2, p. 99-103 5 p.

Research output: Contribution to journal › Article

Genetic Terminator Regions

Streptococcus pyogenes

Operon

RNA

Genes

2007

16 Citations (Scopus)

2DCSi: Identification of protein secondary structure and redox state using 2D cluster analysis of NMR chemical shifts

Wang, C. C., Chen, J. H., Lai, W. C. & Chuang, W-J., 2007 May 1, In : Journal of Biomolecular NMR. 38, 1, p. 57-63 7 p.

Research output: Contribution to journal › Article

Secondary Protein Structure

Cluster analysis

Chemical shift

Oxidation-Reduction

Cluster Analysis

13 Citations (Scopus)

Abrogation of streptococcal pyrogenic exotoxin B-mediated suppression of phagocytosis in U937 cells by Cordyceps sinensis mycelium via production of cytokines

Kuo, C. F., Chen, C. C., Lin, C. F., Jan, M. S., Huang, R. Y., Luo, Y. H., Chuang, W-J., Sheu, C. C. & Lin, Y-S., 2007 Feb 1, In : Food and Chemical Toxicology. 45, 2, p. 278-285 8 p.

Research output: Contribution to journal › Article

Cordyceps

Ophiocordyceps sinensis

exotoxins

U937 Cells

Mycelium

22 Citations (Scopus)

Phosphatidylinositol 3-kinase/Akt activation by integrin-tumor matrix interaction suppresses Fas-mediated apoptosis in T cells

Su, C. C., Lin, Y. P., Cheng, Y. J., Huang, J. Y., Chuang, W-J., Shan, Y-S. & Yang, B-C., 2007 Oct 1, In : Journal of Immunology. 179, 7, p. 4589-4597 9 p.

Research output: Contribution to journal › Article

Phosphatidylinositol 3-Kinase

Integrins

Apoptosis

T-Lymphocytes

Jurkat Cells

14 Citations (Scopus)

Streptococcal pyrogenic exotoxin B antibodies in a mouse model of glomerulonephritis

Luo, Y. H., Kuo, C. F., Huang, K. J., Wu, J. J., Lei, H. Y., Lin, M. T., Chuang, W-J., Liu, C-C., Lin, C. F. & Lin, Y-S., 2007 Sep 1, In : Kidney International. 72, 6, p. 716-724 9 p.

Research output: Contribution to journal › Article

Exotoxins

Glomerulonephritis

Antibodies

Complement Activation

Proteinuria

4 Citations (Scopus)

The fate of SPE B after internalization and its implication in SPEB-induced apoptosis.

Chang, C. W., Tsai, W. H., Chuang, W-J., Lin, Y-S., Wu, J. J., Liu, C-C., Tsai, P-J. & Lin, M. T., 2007 Jan 1, In : Journal of biomedical science. 14, 3, p. 419-427 9 p.

Research output: Contribution to journal › Article

Apoptosis

Fluorescein-5-isothiocyanate

Chloroquine

Lysosomes

Degradation