Xi-Zhang Lin

Professor

  • 3644 Citations
  • 34 h-Index
1987 …2019
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Research Output 1987 2019

2019

Evaluation Efficacy of Rhenium-188-Loaded Micro-particles for Radiotherapy in a Mouse Model of Hepatocellular Carcinoma

Shih, Y. H., Peng, C. L., Weng, M. F., Chiang, P. F., Luo, T. Y. & Lin, X-Z., 2019 Mar 4, In : Molecular Pharmaceutics. 16, 3, p. 1083-1091 9 p.

Research output: Contribution to journalArticle

Rhenium
Tin
Colloids
Hepatocellular Carcinoma
Radiotherapy
2018
9 Citations (Scopus)

Hepatocellular carcinoma–related cyclin D1 is selectively regulated by autophagy degradation system

Wu, S. Y., Lan, S. H., Wu, S-R., Chiu, Y. C., Lin, X-Z., Su, I. J., Tsai, T. F., Yen, C-J., Lu, T-H., Liang, F. W., Li, C-Y., Su, H-J., Su, C. L. & Liu, H-S., 2018 Jul 1, In : Hepatology. 68, 1, p. 141-154 14 p.

Research output: Contribution to journalArticle

Cyclin D1
Autophagy
Hepatocellular Carcinoma
Neoplasms
Carcinogenesis
9 Citations (Scopus)

Management consensus guideline for hepatocellular carcinoma: 2016 updated by the Taiwan Liver Cancer Association and the Gastroenterological Society of Taiwan

Local ablation group, Surveillance group, Diagnosis group, Staging group, Surgery group, TACE/TARE/HAI group, Target therapy/systemic therapy group, Radiotherapy group, Prevention group & Drafting group, 2018 May 1, In : Journal of the Formosan Medical Association. 117, 5, p. 381-403 23 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Taiwan
Hepatocellular Carcinoma
Consensus
Guidelines
2016
2 Citations (Scopus)

A magnetic induction heating system with multi-cascaded coils and adjustable magnetic circuit for hyperthermia

Huang, C. F., Chao, H. Y., Chang, H. H. & Lin, X-Z., 2016 Jan 2, In : Electromagnetic Biology and Medicine. 35, 1, p. 59-64 6 p.

Research output: Contribution to journalArticle

Electric Impedance
Heating
Fever
NADPH Oxidase
Hematoxylin

Hemostasis Plug for an Electromagnetic Thermotherapy and Its Application for Liver Laceration

Liu, C. H., Huang, S. C., Chao, Y-J., Lin, X-Z. & Lee, G. B., 2016 Apr 1, In : Annals of biomedical engineering. 44, 4, p. 1310-1320 11 p.

Research output: Contribution to journalArticle

Liver
Temperature control
Electromagnetic fields
Surgery
Feedback control
2015
16 Citations (Scopus)
Ethiodized Oil
Porifera
Gelatin
Microspheres
Doxorubicin
2014
2 Citations (Scopus)

An electromagnetic thermotherapy system with a deep penetration depth for percutaneous thermal ablation

Huang, S. C., Chang, Y. Y., Kang, J-W., Tsai, H-W., Shan, Y-S., Lin, X-Z. & Lee, G. B., 2014 Jan 1, In : Annals of biomedical engineering. 42, 1, p. 86-96 11 p.

Research output: Contribution to journalArticle

Ablation
Needles
Electromagnetic fields
Animals
Tissue
23 Citations (Scopus)

Autophagy-preferential degradation of MIR224 participates in hepatocellular carcinoma tumorigenesis

Lan, S. H., Wu, S. Y., Zuchini, R., Lin, X-Z., Su, I. J., Tsai, T. F., Lin, Y. J., Wu, C. T. & Liu, H-S., 2014 Sep 1, In : Autophagy. 10, 9, p. 1687-1689 3 p.

Research output: Contribution to journalArticle

Autophagy
MicroRNAs
Hepatocellular Carcinoma
Carcinogenesis
Amiodarone
101 Citations (Scopus)

Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224

Lan, S. H., Wu, S. Y., Zuchini, R., Lin, X-Z., Su, I. J., Tsai, T. F., Lin, Y. J., Wu, C. T. & Liu, H-S., 2014 Feb 1, In : Hepatology. 59, 2, p. 505-517 13 p.

Research output: Contribution to journalArticle

Autophagy
MicroRNAs
Hepatitis B virus
Hepatocellular Carcinoma
Carcinogenesis
2 Citations (Scopus)

Design techniques for antenna needles used in microwave hyperthermia therapy for tumor treatment

Huang, C. F., Tien, Y. W., Chen, C-Y. & Lin, X-Z., 2014 Jan 1, 2014 IEEE-APS Topical Conference on Antennas and Propagation in Wireless Communications, APWC 2014. Institute of Electrical and Electronics Engineers Inc., p. 37-39 3 p. 6905520. (2014 IEEE-APS Topical Conference on Antennas and Propagation in Wireless Communications, APWC 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hyperthermia therapy
Needles
Tumors
Microwaves
Antennas
2 Citations (Scopus)

Electromagnetic thermotherapy for deep organ ablation by using a needle array under a synchronized-coil system

Huang, S. C., Kang, J-W., Tsai, H-W., Shan, Y-S., Lin, X-Z. & Lee, G. B., 2014 Nov 1, In : IEEE Transactions on Biomedical Engineering. 61, 11, p. 2733-2739 7 p., 6860281.

Research output: Contribution to journalArticle

Ablation
Needles
Electromagnetic fields
Surgery
Tumors
4 Citations (Scopus)

Electromagnetic thermotherapy system with needle arrays: A practical tool for the removal of cancerous tumors

Huang, S. C., Kang, J-W., Tsai, H-W., Shan, Y-S., Lin, X-Z. & Lee, G. B., 2014 Feb, In : IEEE Transactions on Biomedical Engineering. 61, 2, p. 598-605 8 p., 6645388.

Research output: Contribution to journalArticle

Needles
Tumors
Oncology
Medical applications
Ablation
3 Citations (Scopus)

Oxidative Stress and Frailty: A Closer Look at the Origin of a Human Aging Phenotype

Wu, I. C., Hsiung, C. A., Hsu, C. C. & Lin, X-Z., 2014 Jan 1, Aging: Oxidative Stress and Dietary Antioxidants. Elsevier Inc., p. 3-14 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Oxidative Stress
Phenotype
Sarcopenia
Multiple Abnormalities
Endoplasmic Reticulum Stress
3 Citations (Scopus)

Preparation and therapeutic evaluation of (188)Re-thermogelling emulsion in rat model of hepatocellular carcinoma

Shih, Y. H., Lin, X-Z., Yeh, C. H., Peng, C. L., Shieh, M. J., Lin, W. J. & Luo, T. Y., 2014 Jan 1, In : International journal of nanomedicine. 9, p. 4191-4201 11 p.

Research output: Contribution to journalArticle

Hydrogel
Ethiodized Oil
Emulsions
Hydrogels
glycolic acid

深度磁場產生裝置

Lin, X-Z., Huang, S-J. & Tai, C-C., 2014 Mar 26, Patent No. 2398486

Research output: Patent

深度磁場產生裝置

Lin, X-Z., Huang, S-J. & Tai, C-C., 2014 Mar 20, Patent No. 9320912

Research output: Patent

2013
4 Citations (Scopus)
Splenic Artery
Spleen
Cone-Beam Computed Tomography
Liver Function Tests
Porifera
1 Citation (Scopus)

Partial nephrectomy without renal ischemia using an electromagnetic thermal surgery system in a porcine model

Ou, J-H., Yang, W-H., Tsai, H-W., Lee, T. J., Chen, S. Y., Huang, S. C., Chang, Y. Y., Lee, G. B. & Lin, X-Z., 2013 May 1, In : Urology. 81, 5, p. 1101-1107 7 p.

Research output: Contribution to journalArticle

Electromagnetic Phenomena
Nephrectomy
Swine
Ischemia
Hot Temperature
4 Citations (Scopus)

Successfully seal pancreatic end after thermal distal pancreatectomy using needle arrays in alternating electromagnetic fields

Chao, Y-J., Shan, Y-S., Zuchini, R., Tsai, H-W., Lin, P. W., Lee, G. B. & Lin, X-Z., 2013 Apr 1, In : Surgical Innovation. 20, 2, p. 150-157 8 p.

Research output: Contribution to journalArticle

Pancreatectomy
Electromagnetic Fields
Magnetic Fields
Needles
Hot Temperature
6 Citations (Scopus)

Using modern teaching strategies to teach upper abdominal sonography to medical students

Cheng, W. C., Lin, X-Z. & Chen, C-Y., 2013 Jul 1, In : Journal of the Chinese Medical Association. 76, 7, p. 395-400 6 p.

Research output: Contribution to journalArticle

Medical Students
Ultrasonography
Teaching
Students
Learning
2012
6 Citations (Scopus)

Dual-row needle arrays under an electromagnetic thermotherapy system for bloodless liver resection surgery

Huang, S. C., Chang, Y. Y., Chao, Y-J., Shan, Y-S., Lin, X-Z. & Lee, G. B., 2012 Mar 1, In : IEEE Transactions on Biomedical Engineering. 59, 3, p. 824-831 8 p., 6108353.

Research output: Contribution to journalArticle

Liver
Needles
Surgery
Tissue
Coagulation
11 Citations (Scopus)
Ethiodized Oil
Nitroglycerin
Hepatocellular Carcinoma
Neoplasms
Absorbable Gelatin Sponge
5 Citations (Scopus)

Tailored nanoparticles for tumour therapy

Jiang, P. S., Drake, P., Cho, H. J., Kao, C. H., Lee, K. F., Kuo, C. H., Lin, X-Z. & Lin, Y. J., 2012, In : Journal of Nanoscience and Nanotechnology. 12, 6, p. 5076-5081 6 p.

Research output: Contribution to journalArticle

Nanoparticles
Tumors
therapy
tumors
nanoparticles
2011

A new inductive thermotherapy system for minimal invasive surgery in splenomegaly

Huang, S. C., Chang, Y. Y., Lin, X-Z. & Lee, G. B., 2011, Proceedings of the 8th IASTED International Conference on Biomedical Engineering, Biomed 2011. p. 220-226 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Surgery
Coagulation
Temperature control
Needles
Electromagnetic fields

Clinical importance of adverse effect in long term use of proton-pump inhibitors

Cheng, W. C., Chen, C-Y. & Lin, X-Z., 2011 Oct 1, In : Journal of Internal Medicine of Taiwan. 22, 5, p. 304-313 10 p.

Research output: Contribution to journalArticle

Proton Pump Inhibitors
clopidogrel
Bone Fractures
Drug Interactions
Acids
11 Citations (Scopus)

Electromagnetic thermotherapy using fine needles for hepatoma treatment

Zuchini, R., Tsai, H-W., Chen, C-Y., Huang, C. H., Huang, S. C., Lee, G. B., Huang, C. F. & Lin, X-Z., 2011 Jul 1, In : European Journal of Surgical Oncology. 37, 7, p. 604-610 7 p.

Research output: Contribution to journalArticle

Induced Hyperthermia
Electromagnetic Phenomena
Needles
Hepatocellular Carcinoma
Magnetic Fields
5 Citations (Scopus)

Partial splenectomy using an electromagnetic thermal surgery system in a porcine model

Lo, C. J., Chen, C-Y., Tsai, H-W., Zuchini, R., Lee, G. B. & Lin, X-Z., 2011 Mar 1, In : International Journal of Hyperthermia. 27, 2, p. 108-115 8 p.

Research output: Contribution to journalArticle

Electromagnetic Phenomena
Splenectomy
Swine
Spleen
Hot Temperature
19 Citations (Scopus)

Selection of alkaline phosphatase-positive induced pluripotent stem cells from human amniotic fluid-derived cells by feeder-free system

Lu, H. E., Tsai, M. S., Yang, Y. C., Yuan, C. C., Wang, T. H., Lin, X-Z., Tseng, C. P. & Hwang, S. M., 2011 Jan 1, In : Experimental Cell Research. 317, 13, p. 1895-1903 9 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Cell-Free System
Amniotic Fluid
Alkaline Phosphatase
Phosphates
2010

APPARATUS FOR ELECTROMAGNETIC HYPERTHERMIA THERAPY

Lin, X-Z., 2010 Oct 1, Patent No. I397398

Research output: Patent

10 Citations (Scopus)

Bloodless liver resection using needle arrays under alternating electromagnetic fields

Shan, Y-S., Zuchini, R., Tsai, H-W., Lin, P. W., Lee, G. B. & Lin, X-Z., 2010 Jan 1, In : Surgical Innovation. 17, 2, p. 95-100 6 p.

Research output: Contribution to journalArticle

Electromagnetic Fields
Needles
Liver
Segmental Mastectomy
Swine
5 Citations (Scopus)

Design and construction of a hyperthermia system with improved interaction of magnetic induction-heating

Huang, C. F., Lin, X-Z. & Lo, W. H., 2010 Dec 1, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10. p. 3229-3232 4 p. 5627199. (2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Induction heating
Electromagnetic induction
Heating
Fever
Magnetic circuits
7 Citations (Scopus)

Electromagnetic thermal surgery system for liver resection: An animal study

Chen, C-Y., Zuchini, R., Tsai, H-W., Huang, C. H., Huang, S. C., Lee, G. B. & Lin, X-Z., 2010 Sep 1, In : International Journal of Hyperthermia. 26, 6, p. 604-609 6 p.

Research output: Contribution to journalArticle

Electromagnetic Phenomena
Hot Temperature
Needles
Liver
Magnetic Fields
13 Citations (Scopus)

Electromagnetic thermoablation to treat thrombocytopenia in cirrhotic and hypersplenic rats

Zuchini, R., Huang, C. H., Tsai, H-W., Huang, S. C., Lin, C. P., Chen, C-Y., Lee, G. B. & Lin, X-Z., 2010 Jan 1, In : Journal of Gastroenterology and Hepatology (Australia). 25, 9, p. 1578-1586 9 p.

Research output: Contribution to journalArticle

Electromagnetic Phenomena
Thrombocytopenia
Hypersplenism
Spleen
Platelet Count
18 Citations (Scopus)

Hydrogel-delivered GM-CSF overcomes nonresponsiveness to hepatitis B vaccine through the recruitment and activation of dendritic cells

Chou, H. Y., Lin, X-Z., Pan, W. Y., Wu, P. Y., Chang, C. M., Lin, T. Y., Shen, H. H. & Tao, M. H., 2010 Nov 1, In : Journal of Immunology. 185, 9, p. 5468-5475 8 p.

Research output: Contribution to journalArticle

Hepatitis B Vaccines
Hydrogel
Granulocyte-Macrophage Colony-Stimulating Factor
Hepatitis B
Dendritic Cells
1 Citation (Scopus)

Hydropneumothorax

Chen, P. H. & Lin, X-Z., 2010 Jan 21, In : New England Journal of Medicine. 362, 3

Research output: Contribution to journalArticle

Hydropneumothorax
Hydrothorax
Paracentesis
Pulmonary Atelectasis
Liver Cirrhosis
27 Citations (Scopus)

Low serum testosterone and frailty in older men and women

Wu, I. C., Lin, X-Z., Liu, P. F., Tsai, W. L. & Shiesh, S-C., 2010 Dec 1, In : Maturitas. 67, 4, p. 348-352 5 p.

Research output: Contribution to journalArticle

Testosterone
Serum
Odds Ratio
Confidence Intervals
Hand Strength
2009
18 Citations (Scopus)

A microfluidic device for separation of amniotic fluid mesenchymal stem cells utilizing louver-array structures

Wu, H. W., Lin, X-Z., Hwang, S. M. & Lee, G. B., 2009 Dec 1, In : Biomedical Microdevices. 11, 6, p. 1297-1307 11 p.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Microfluidics
Amniotic Fluid
Cell- and Tissue-Based Therapy
Stem cells

Application of magnetic circuit and multiple-coils array in induction heating for improving localized hyperthermia

Huang, C. F., Lin, X-Z. & Yang, Y. R., 2009 Oct 1, In : World Academy of Science, Engineering and Technology. 58, p. 724-727 4 p.

Research output: Contribution to journalArticle

Induction heating
Magnetic circuits
Electromagnetic induction
Magnetic fields
Hardware
1 Citation (Scopus)

Clulture and diferentiation of amniotic stem cells in a microfluidic system

Wu, H. W., Lin, X-Z., Hwang, S. M. & Lee, G. B., 2009 Dec 11, TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems. p. 2381-2384 4 p. 5285452. (TRANSDUCERS 2009 - 15th International Conference on Solid-State Sensors, Actuators and Microsystems).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Stem cells
Microfluidics
Phosphatases
Microchannels
Fluids
35 Citations (Scopus)

Electroporation-mediated IL-12 gene therapy in a transplantable canine cancer model

Chuang, T. F., Lee, S. C., Liao, K. W., Hsiao, Y. W., Lo, C. H., Chiang, B. L., Lin, X-Z., Tao, M. H. & Chu, R. M., 2009 Aug 1, In : International Journal of Cancer. 125, 3, p. 698-707 10 p.

Research output: Contribution to journalArticle

Electroporation
Interleukin-12
Genetic Therapy
Canidae
Veterinary Venereal Tumors
7 Citations (Scopus)

Evaluating the potential of 188re-ecd/lipiodol as a therapeutic radiopharmaceutical by intratumoral injection for hepatoma treatment

Luo, T. Y., Shih, Y. H., Chen, C-Y., Tang, I. C., Wu, Y. L., Kung, H. C., Lin, W. J. & Lin, X-Z., 2009 Oct 1, In : Cancer Biotherapy and Radiopharmaceuticals. 24, 5, p. 535-541 7 p.

Research output: Contribution to journalArticle

Ethiodized Oil
Radiopharmaceuticals
Hepatocellular Carcinoma
Injections
Therapeutics
11 Citations (Scopus)
Klatskin Tumor
Drainage
Bilirubin
Bile
Prothrombin Time

High Frequency Electromagnetic Thermotherapy for Cancer Treatment

Huang, S. C., Huang, C. H., Lin, X-Z. & Lee, G. B., 2009 Dec 1, 13th International Conference on Biomedical Engineering - ICBME 2008. p. 574-577 4 p. (IFMBE Proceedings; vol. 23).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Oncology
Tumors
Needles
Animals
Magnetic materials
63 Citations (Scopus)

High oxidative stress is correlated with frailty in elderly Chinese

Wu, I. C., Shiesh, S-C., Kuo, P. H. & Lin, X-Z., 2009 Sep 1, In : Journal of the American Geriatrics Society. 57, 9, p. 1666-1671 6 p.

Research output: Contribution to journalArticle

Oxidative Stress
Waist-Hip Ratio
C-Reactive Protein
Serum
Serum Albumin

Liver resection using high frequency electromagnetic thermotherapy

Huang, S. C., Tsai, H-W., Huang, C. H., Zuchini, R., Lo, C. J., Lin, X-Z. & Lee, G. B., 2009 Dec 1, World Congress on Medical Physics and Biomedical Engineering - Surgery, Minimal Invasive Interventions, Endoscopy and Image Guided Therapy. 6 ed. p. 8-11 4 p. (IFMBE Proceedings; vol. 25, no. 6).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Liver
Surgery
Needles
Animals
Magnetic materials
37 Citations (Scopus)

Localised heating of tumours utilising injectable magnetic nanoparticles for hyperthermia cancer therapy

Tseng, H. Y., Lee, G. B., Lee, C. Y., Shih, Y. H. & Lin, X-Z., 2009 Jun 11, In : IET Nanobiotechnology. 3, 2, p. 46-54 9 p.

Research output: Contribution to journalArticle

Nanoparticles
Heating
Tumors
Fever
Injections

The clinical role of the treatment for hypersplenism in patients with cirrhosis

Shing, C., Chen, C-Y. & Lin, X-Z., 2009 Oct, In : Journal of Internal Medicine of Taiwan. 20, 5, p. 403-408 6 p.

Research output: Contribution to journalArticle

Hypersplenism
Splenomegaly
Fibrosis
Portal Hypertension
Thrombocytopenia
15 Citations (Scopus)

The culture and differentiation of amniotic stem cells using a microfluidic system

Wu, H. W., Lin, X-Z., Hwang, S. M. & Lee, G. B., 2009 Apr 16, In : Biomedical Microdevices. 11, 4, p. 869-881 13 p.

Research output: Contribution to journalArticle

Microfluidics
Stem cells
Mesenchymal Stromal Cells
Cell culture
Stem Cells
2008
7 Citations (Scopus)

Clinical and imaging characteristics relating to surgical outcomes of perforated appendicitis

Tsai, H-M., Shan, Y-S., Lin, P. W., Lin, X-Z. & Chen, C-Y., 2008 Jan, In : Hepato-Gastroenterology. 55, 81, p. 127-132 6 p.

Research output: Contribution to journalArticle

Appendicitis
Appendectomy
Inflammation
Abscess
Fats