• 2616 Citations
  • 24 h-Index
1990 …2020
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Personal profile


  • 2004 PhD, Institute of Clinical Medicine, National Cheng Kung University


  • 1998.08~Present Surgeon/Department of Surgery, NCKUH
  • 2002.08~2008.07 Assistant professor/Department of Surgery, NCKU
  • 2008.08~ 2012.07 Associate professor/Department of Surgery, NCKU
  • 2010.08~2012.07 Associate professor/Institute of Clinical Medicine, NCKU
  • 2010.10~Present Convener of UGI Cancer/NCKUH
  • 2012.08~2016.07 Professor/Institute of Clinical Medicine, NCKU
  • 2016.08~Present Director/Department of Clinical Medical Research, NCKUH
  • 2016.08~Present Distinguished Professor/Institute of Clinical Medicine, NCKU
  • 2017.08~Present Director/Institute of Clinical Medicine, NCKU

Research Interests

  • Gastrointestinal physiology
  • GI Clinical Oncology
  • Tumor microenvironment (interaction between cancer cells and stromal cells)
  • Liver Fibrosis and Regeneration

Fingerprint Dive into the research topics where Yan-Shen Shan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 32 Similar Profiles
gemcitabine Medicine & Life Sciences
Pancreatic Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Pancreaticoduodenectomy Medicine & Life Sciences
oxaliplatin Medicine & Life Sciences
Stomach Neoplasms Medicine & Life Sciences
Gastrointestinal Stromal Tumors Medicine & Life Sciences
Adenocarcinoma Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2000 2020

Research Output 1990 2020

A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study

Chiang, N. J., Tsai, K. K., Hsiao, C. F., Yang, S. H., Hsiao, H. H., Shen, W. C., Hsu, C., Lin, Y. L., Chen, J. S., Shan, Y. S. & Chen, L. T., 2020 Jan, In : European Journal of Cancer. 124, p. 123-130 8 p.

Research output: Contribution to journalArticle

Stomach Neoplasms
Lymph Node Excision
1 Citation (Scopus)
Open Access
Hepatic Stellate Cells
Insulin Resistance
Gastrointestinal Stromal Tumors
Sequence Deletion

Experience of applying cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian teratoma with malignant transformation and peritoneal dissemination

Yu, H. H., Yonemura, Y., Hsieh, M. C., Lu, C. Y., Wu, S. Y. & Shan, Y. S., 2019 Jan 1, In : Therapeutics and Clinical Risk Management. 15, p. 129-136 8 p.

Research output: Contribution to journalArticle

Open Access
Drug Therapy


Effect of extracellular matrix stiffness on pancreatic stellate cell activation in pancreatic cancer

Author: 方馨, 曹., 2018 Aug 10

Supervisor: Shan, Y. (Supervisor)

Student thesis: Master's Thesis

Identification of potential risk factors in the incidence and progression of malignant gliomas

Author: 志偉, 陳., 2018 Jan 31

Supervisor: Shan, Y. (Supervisor)

Student thesis: Doctoral Thesis

Investigating IFN-gamma Susceptibility and Oncogenic Regulation in Gastric Cancer Cells

Author: 柏鈞, 曾., 2016 Jan 27

Supervisor: Shan, Y. (Supervisor)

Student thesis: Doctoral Thesis

Spleen-derived mesenchymal stem cells promote progression of pancreatic cancer

Author: 予, 吳., 2017 Feb 7

Supervisor: Shan, Y. (Supervisor)

Student thesis: Master's Thesis