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Yan-Shen Shan

Professor

  • 2775 Citations
  • 24 h-Index
1990 …2020

Research output per year

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Personal profile

Education

  • 2004 PhD, Institute of Clinical Medicine, National Cheng Kung University

Experience

  • 1998.08~Present Surgeon/Department of Surgery, NCKUH
  • 2002.08~2008.07 Assistant professor/Department of Surgery, NCKU
  • 2008.08~ 2012.07 Associate professor/Department of Surgery, NCKU
  • 2010.08~2012.07 Associate professor/Institute of Clinical Medicine, NCKU
  • 2010.10~Present Convener of UGI Cancer/NCKUH
  • 2012.08~2016.07 Professor/Institute of Clinical Medicine, NCKU
  • 2016.08~Present Director/Department of Clinical Medical Research, NCKUH
  • 2016.08~Present Distinguished Professor/Institute of Clinical Medicine, NCKU
  • 2017.08~Present Director/Institute of Clinical Medicine, NCKU

Research Interests

  • Gastrointestinal physiology
  • GI Clinical Oncology
  • Tumor microenvironment (interaction between cancer cells and stromal cells)
  • Liver Fibrosis and Regeneration

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Projects

臺灣上消化道癌症臨床試驗合作聯盟 III

Shan, Y.

19-05-01 → 20-04-30

Project: Research project

多面向評估腫瘤與微環境之重設在胰臟癌致病機轉與標靶治療藥物發展之角色-腫瘤微環境對於胰腺癌惡病質與轉移的影響(2/3)子計畫一

Shan, Y.

17-08-01 → 18-07-31

Project: Research project

剖析胰臟癌發生過程中免疫調節成份之功能性變化-癌細胞與免疫浸潤巨噬細胞交互作用對胰臟癌生成過程中的免疫調節之影響(1/3)

Shan, Y.

17-08-01 → 18-07-31

Project: Research project

臺灣上消化道癌症臨床試驗合作聯盟

Shan, Y.

17-05-01 → 18-04-30

Project: Research project

胰腺癌幹細胞及腫瘤微環境間之交互作用及其轉譯應用-骨調素在胰臟癌幹細胞中可促進自噬作用活性(3/3)

Shan, Y.

16-08-01 → 17-07-31

Project: Research project

Research Output

A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study

Chiang, N. J., Tsai, K. K., Hsiao, C. F., Yang, S. H., Hsiao, H. H., Shen, W. C., Hsu, C., Lin, Y. L., Chen, J. S., Shan, Y. S. & Chen, L. T., 2020 Jan, In : European Journal of Cancer. 124, p. 123-130 8 p.

Research output: Contribution to journal › Article

    • 1 Citation (Scopus)

    An Open-Label, Single-Arm, Two-Stage, Multicenter, Phase II Study to Evaluate the Efficacy of TLC388 and Genomic Analysis for Poorly Differentiated Neuroendocrine Carcinomas

    Chen, M. H., Chou, W. C., Hsiao, C. F., Jiang, S. S., Tsai, H. J., Liu, Y. C., Hsu, C., Shan, Y. S., Hung, Y. P., Hsich, C. H., Chiu, C. H., Liu, T. C., Cho, S. F., Liu, T. W. & Chao, Y., 2020 May 1, In : Oncologist. 25, 5, p. e782-e788

    Research output: Contribution to journal › Article

    Open Access

    • Application of piezoelectric actuator to simplified haptic feedback system

    Yeh, C. H., Su, F. C., Shan, Y. S., Dosaev, M., Selyutskiy, Y., Goryacheva, I. & Ju, M. S., 2020 Mar 1, In : Sensors and Actuators, A: Physical. 303, 111820.

    Research output: Contribution to journal › Article

    • Exploring Circulating Tumor Cells in Cholangiocarcinoma Using a Novel Glycosaminoglycan Probe on a Microfluidic Platform

    Gopinathan, P., Chiang, N. J., Bandaru, A., Sinha, A., Huang, W. Y., Hung, S. C., Shan, Y. S. & Lee, G. B., 2020 Jan 1, (Accepted/In press) In : Advanced Healthcare Materials.

    Research output: Contribution to journal › Article

    • Liposomal irinotecan in metastatic pancreatic adenocarcinoma in Asian patients: Subgroup analysis of the NAPOLI-1 study

    Bang, Y. J., Li, C. P., Lee, K. H., Chiu, C. F., Park, J. O., Shan, Y. S., Kim, J. S., Chen, J. S., Shim, H. J., Rau, K. M., Choi, H. J., Oh, D. Y., Belanger, B. & Chen, L. T., 2020 Feb 1, In : Cancer Science. 111, 2, p. 513-527 15 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Citation (Scopus)

    Thesis

    Effect of extracellular matrix stiffness on pancreatic stellate cell activation in pancreatic cancer

    Author: 方馨, 曹., 2018 Aug 10

    Supervisor: Shan, Y. (Supervisor)

    Student thesis: Master's Thesis

    Identification of potential risk factors in the incidence and progression of malignant gliomas

    Author: 志偉, 陳., 2018 Jan 31

    Supervisor: Shan, Y. (Supervisor)

    Student thesis: Doctoral Thesis

    Investigating IFN-gamma Susceptibility and Oncogenic Regulation in Gastric Cancer Cells

    Author: 柏鈞, 曾., 2016 Jan 27

    Supervisor: Shan, Y. (Supervisor)

    Student thesis: Doctoral Thesis

    Investigating the clinical significance of hepatectomy: glutamine supplementation in liver regeneration and clinical outcome of miRNA in hepatocellular carcinoma

    Author: 家聖, 顏., 2019

    Supervisor: Shan, Y. (Supervisor)

    Student thesis: Doctoral Thesis

    Spleen-derived mesenchymal stem cells promote progression of pancreatic cancer

    Author: 予, 吳., 2017 Feb 7

    Supervisor: Shan, Y. (Supervisor)

    Student thesis: Master's Thesis