• 2464 Citations
  • 24 h-Index
1990 …2020
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Research Output 1990 2019

2019
Stomach Neoplasms
Liver
Robotics
Punctures
Lymph Node Excision
Open Access
pioglitazone
Diet
Hepatic Stellate Cells
Insulin Resistance
Autophagy
Ficus
Gastrointestinal Stromal Tumors
Sequence Deletion
Codon
Exons

Experience of applying cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian teratoma with malignant transformation and peritoneal dissemination

Yu, H. H., Yonemura, Y., Hsieh, M. C., Lu, C. Y., Wu, S. Y. & Shan, Y-S., 2019 Jan 1, In : Therapeutics and Clinical Risk Management. 15, p. 129-136 8 p.

Research output: Contribution to journalArticle

Open Access
Chemotherapy
Teratoma
Surgery
surgery
Drug Therapy
Open Access
cardiac arrest
rating scales
Heart Arrest
Retrospective Studies
Emergency rooms
1 Citation (Scopus)

Loss of the transcriptional repressor TGIF1 results in enhanced Kras-driven development of pancreatic cancer

Weng, C. C., Hsieh, M. J., Wu, C. C., Lin, Y. C., Shan, Y-S., Hung, W. C., Chen, L. T. & Cheng, K. H., 2019 May 20, In : Molecular cancer. 18, 1, 96.

Research output: Contribution to journalArticle

Open Access
Pancreatic Neoplasms
Adenocarcinoma
Epithelial-Mesenchymal Transition
Neoplasm Metastasis
Epigenomics
1 Citation (Scopus)

Low cd8+ t cell infiltration and high pd-l1 expression are associated with level of cd44+/cd133+ cancer stem cells and predict an unfavorable prognosis in pancreatic cancer

Hou, Y. C., Chao, Y-J., Hsieh, M. H., Tung, H. L., Wang, H. C. & Shan, Y-S., 2019 Apr 1, In : Cancers. 11, 4, 541.

Research output: Contribution to journalArticle

Open Access
Death Domain Receptors
Neoplastic Stem Cells
Pancreatic Neoplasms
Ligands
T-Lymphocytes

Nuclear KIT induces a NFKBIB-RELA-KIT autoregulatory loop in imatinib-resistant gastrointestinal stromal tumors

Hsueh, Y. S., Chang, H. H., Shan, Y. S., Sun, H. S., Fletcher, J. A., Li, C. F. & Chen, L. T., 2019 Sep 19, In : Oncogene. 38, 38, p. 6550-6565 16 p.

Research output: Contribution to journalArticle

Open Access
Gastrointestinal Stromal Tumors
Stromal Cells
Chromatin Immunoprecipitation
Valproic Acid
Carcinogenesis

Pancreatic stellate cells activated by mutant KRAS-mediated PAI-1 upregulation foster pancreatic cancer progression via IL-8

Wang, H. C., Lin, Y. L., Hsu, C. C., Chao, Y. J., Hou, Y. C., Chiu, T. J., Huang, P. H., Tang, M. J., Chen, L. T. & Shan, Y. S., 2019 Jan 1, In : Theranostics. 9, 24, p. 7168-7183 16 p.

Research output: Contribution to journalArticle

Open Access
Pancreatic Stellate Cells
Plasminogen Activator Inhibitor 1
Interleukin-8
Pancreatic Neoplasms
Up-Regulation
3 Citations (Scopus)

Protein arginine methyltransferase 3 enhances chemoresistance in pancreatic cancer by methylating hnRNPA1 to increase ABCG2 expression

Hsu, M. C., Pan, M. R., Chu, P. Y., Tsai, Y. L., Tsai, C. H., Shan, Y-S., Chen, L. T. & Hung, W. C., 2019 Jan 1, In : Cancers. 11, 1, 8.

Research output: Contribution to journalArticle

Open Access
Protein-Arginine N-Methyltransferases
Pancreatic Neoplasms
gemcitabine
Adenosine Triphosphate
Drug Resistance

Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer

Hsu, M. C., Tsai, Y. L., Lin, C. H., Pan, M. R., Shan, Y-S., Cheng, T. Y., Cheng, S. H. C., Chen, L. T. & Hung, W. C., 2019 Jul 19, In : Journal of Hematology and Oncology. 12, 1, 79.

Research output: Contribution to journalArticle

Open Access
Protein-Arginine N-Methyltransferases
Glyceraldehyde-3-Phosphate Dehydrogenases
Pancreatic Neoplasms
Respiration
Oxidative Phosphorylation
2 Citations (Scopus)

β-catenin-activated autocrine PDGF/Src signaling is a therapeutic target in pancreatic cancer

Kuo, T. L., Cheng, K. H., Shan, Y-S., Chen, L. T. & Hung, W. C., 2019 Jan 1, In : Theranostics. 9, 2, p. 324-336 13 p.

Research output: Contribution to journalArticle

Open Access
Catenins
Platelet-Derived Growth Factor
Pancreatic Neoplasms
Neoplasms
Mutation
2018
4 Citations (Scopus)

Fucoidan inhibits radiation-induced pneumonitis and lung fibrosis by reducing inflammatory cytokine expression in lung tissues

Yu, H. H., Chengchuan, E. K. O., Chang, C. L., Yuan, K. S. P., Wu, A. T. H., Shan, Y-S. & Wu, S. Y., 2018 Oct 19, In : Marine Drugs. 16, 10, 392.

Research output: Contribution to journalArticle

Radiation Pneumonitis
Fibrosis
Cytokines
Lung
Radiotherapy
1 Citation (Scopus)

Laparoscopic surgery for large left lateral liver tumors: safety and oncologic outcomes

Yang, T-H., Chen, J. L., Lin, Y-J., Chao, Y-J., Shan, Y-S., Hsu, H-P., Su, C-M., Chou, C. C. & Yen, Y-T., 2018 Oct 1, In : Surgical Endoscopy. 32, 10, p. 4314-4320 7 p.

Research output: Contribution to journalArticle

Laparoscopy
Segmental Mastectomy
Safety
Liver
Neoplasms
2 Citations (Scopus)

Survival with nal-IRI (liposomal irinotecan) plus 5-fluorouracil and leucovorin versus 5-fluorouracil and leucovorin in per-protocol and non-per-protocol populations of NAPOLI-1: Expanded analysis of a global phase 3 trial

Chen, L. T., Siveke, J. T., Wang-Gillam, A., Li, C. P., Bodoky, G., Dean, A. P., Shan, Y-S., Jameson, G. S., Macarulla, T., Lee, K. H., Cunningham, D., Blanc, J. F., Chiu, C. F., Schwartsmann, G., Braiteh, F. S., Mamlouk, K., Belanger, B., de Jong, F. A. & Hubner, R. A., 2018 Dec 1, In : European Journal of Cancer. 105, p. 71-78 8 p.

Research output: Contribution to journalArticle

irinotecan
Leucovorin
Fluorouracil
Survival
Population
Pneumoperitoneum
Endometrial Neoplasms
Ventral Hernia
Hernia
Gynecologic Surgical Procedures
1 Citation (Scopus)

The clinical impact of the novel tumor marker DR-70 in unresectable gastric cancer patients

Hung, Y. P., Chen, M. H., Lin, J. S., Hsiao, C. F., Shan, Y-S., Chen, Y. C., Chen, L. T., Liu, T. W., Li, C. P. & Chao, Y., 2018 Jul 1, In : Journal of the Chinese Medical Association. 81, 7, p. 593-598 6 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
Stomach Neoplasms
Carcinoembryonic Antigen
Antigens
Drug Therapy
1 Citation (Scopus)

The decrease of glycolytic enzyme hexokinase 1 accelerates tumor malignancy via deregulating energy metabolism but sensitizes cancer cells to 2-deoxyglucose inhibition

Tseng, P. L., Chen, C. W., Hu, K. H., Cheng, H. C., Lin, Y. H., Tsai, W. H., Cheng, T. J., Wu, W. H., Yeh, C. W., Lin, C. C., Tsai, H. J., Chang, H. C., Chuang, J. H., Shan, Y. S. & Chang, W. T., 2018 Apr 10, In : Oncotarget. 9, 27, p. 18949-18969 21 p.

Research output: Contribution to journalArticle

Hexokinase
Deoxyglucose
Energy Metabolism
Enzymes
Neoplasms
2 Citations (Scopus)

The incidence and survival of pancreatic cancer by histology, including rare subtypes: a nation-wide cancer registry-based study from Taiwan

Chang, J. S., Chen, L. T., Shan, Y. S., Chu, P. Y., Tsai, C. R. & Tsai, H. J., 2018 Nov, In : Cancer medicine. 7, 11, p. 5775-5788 14 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Taiwan
Registries
Histology
Adenocarcinoma
1 Citation (Scopus)

Vitelline fistula associated with omphalocele: Diagnostic dilemma?

Shih, C. W., Shan, Y-S. & Lin, C-H., 2018 Jan 1, In : International Journal of Surgery Case Reports. 47, p. 45-47 3 p.

Research output: Contribution to journalArticle

Umbilical Hernia
Fistula
Meconium
Umbilical Cord
Intestines
2017
1 Citation (Scopus)
Fats
Tomography
Biopsy
Needle Biopsy
Pancreatitis

A Microfluidic Chip for Detecting Cholangiocarcinoma Cells in Human Bile

Hung, L. Y., Chiang, N. J., Tsai, W. C., Fu, C. Y., Wang, Y. C., Shan, Y-S. & Lee, G. B., 2017 Dec 1, In : Scientific reports. 7, 1, 4248.

Research output: Contribution to journalArticle

Microfluidics
Cholangiocarcinoma
Bile
Bile Duct Neoplasms
Neoplasms

A microfluidic system for detection of cholangiocarcinoma cells by using heparan sulfate octasaccharides

Tsai, W. C., Hung, L. Y., Huang, T. Y., Shan, Y-S., Hung, S. C. & Lee, G. B., 2017 Aug 25, 2017 IEEE 12th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017. Institute of Electrical and Electronics Engineers Inc., p. 489-493 5 p. 8017070. (2017 IEEE 12th International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2017).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Heparitin Sulfate
Microfluidics
beads
sulfates
cells
7 Citations (Scopus)

An opportunity in difficulty: Japan–Korea–Taiwan expert Delphi consensus on surgical difficulty during laparoscopic cholecystectomy

Iwashita, Y., Hibi, T., Ohyama, T., Honda, G., Yoshida, M., Miura, F., Takada, T., Han, H. S., Hwang, T. L., Shinya, S., Suzuki, K., Umezawa, A., Yoon, Y. S., Choi, I. S., Huang, W. S. W., Chen, K. H., Watanabe, M., Abe, Y., Misawa, T., Nagakawa, Y. & 43 others, Yoon, D. S., Jang, J. Y., Yu, H. C., Ahn, K. S., Kim, S. C., Song, I. S., Kim, J. H., Yun, S. S., Choi, S. H., Jan, Y. Y., Shan, Y-S., Ker, C. G., Chan, D. C., Wu, C. C., Lee, K. T., Toyota, N., Higuchi, R., Nakamura, Y., Mizuguchi, Y., Takeda, Y., Ito, M., Norimizu, S., Yamada, S., Matsumura, N., Shindoh, J., Sunagawa, H., Gocho, T., Hasegawa, H., Rikiyama, T., Sata, N., Kano, N., Kitano, S., Tokumura, H., Yamashita, Y., Watanabe, G., Nakagawa, K., Kimura, T., Yamakawa, T., Wakabayashi, G., Mori, R., Endo, I., Miyazaki, M. & Yamamoto, M., 2017 Apr 1, In : Journal of Hepato-Biliary-Pancreatic Sciences. 24, 4, p. 191-198 8 p.

Research output: Contribution to journalArticle

Laparoscopic Cholecystectomy
Cicatrix
Cholecystitis
Korea
Taiwan
8 Citations (Scopus)

Automated selection of aptamers against cholangiocarcinoma cells on an integrated microfluidic platform

Gopinathan, P., Hung, L. Y., Wang, C. H., Chiang, N. J., Wang, Y. C., Shan, Y-S. & Lee, G. B., 2017 Jul 1, In : Biomicrofluidics. 11, 4, 044101.

Research output: Contribution to journalArticle

Microfluidics
Cholangiocarcinoma
platforms
cells
Ligands
13 Citations (Scopus)

Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer

Shan, Y-S., Hsu, H-P., Lai, M-D., Hung, Y. H., Wang, C. Y., Yen, M. C. & Chen, Y. L., 2017 Jan 1, In : Oncology Letters. 14, 4, p. 4517-4526 10 p.

Research output: Contribution to journalArticle

Cyclin D1
Stomach Neoplasms
Cyclin D2
Stomach
Cyclin D
14 Citations (Scopus)

Dysregulation of Rab37-mediated cross-talk between cancer cells and endothelial cells via thrombospondin-1 promotes tumor neovasculature and metastasis

Tzeng, H. T., Tsai, C. H., Yen, Y-T., Cheng, H-C., Chen, Y. C., Pu, S. W., Wang, Y. S., Shan, Y-S., Tseng, Y-L., Su, W-C., Lai, W-W., Wu, L-W. & Wang, Y-C., 2017 May 1, In : Clinical Cancer Research. 23, 9, p. 2335-2345 11 p.

Research output: Contribution to journalArticle

Thrombospondin 1
Endothelial Cells
Neoplasm Metastasis
Tumor Microenvironment
Exocytosis

Effectiveness of trauma team on medical resource utilization and quality of care for patients with major trauma

Wang, C. J., Yen, S. T., Huang, S. F., Hsu, S. C., Ying, J. C. & Shan, Y. S., 2017 Jul 24, In : BMC Health Services Research. 17, 1, 505.

Research output: Contribution to journalArticle

Quality of Health Care
Wounds and Injuries
Databases
Health Expenditures
Taiwan
5 Citations (Scopus)

Increased risk of brain cancer incidence in stroke patients: A clinical case series, population-based and longitudinal follow-up study

Chen, C. W., Cheng, T. J., Ho, C. H., Wang, J. J., Weng, S. F., Hou, Y. C., Cheng, H. C., Chio, C. C., Shan, Y. S. & Chang, W. T., 2017 Jan 1, In : Oncotarget. 8, 65, p. 108989-108999 11 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Stroke
Incidence
Population
Confidence Intervals

Laparoscopic pancreaticoduodenectomy

Chao, Y-J. & Shan, Y-S., 2017 Jul 19, Innovation of Diagnosis and Treatment for Pancreatic Cancer. Springer Singapore, p. 129-145 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) regulates the cell metabolism of pancreatic neuroendocrine tumors (pNET) and de-sensitizes pNET to mTOR inhibitors

Chu, P. Y., Jiang, S. S., Shan, Y. S., Hung, W. C., Chen, M. H., Lin, H. Y., Chen, Y. L., Tsai, H. J. & Chen, L. T., 2017 Jan 1, In : Oncotarget. 8, 61, p. 103613-103625 13 p.

Research output: Contribution to journalArticle

Phosphoenolpyruvate
Neuroendocrine Tumors
Neuroendocrine Cells
Glycolysis
Neoplasms

Screening of peptide specific to cholangiocarcinoma cancer cells using an integrated microfluidic system and phage display technology

Yu, C. W., Fu, C. Y., Hung, L. Y., Wang, C. H., Chiang, N. J., Wang, Y. C., Shan, Y-S. & Lee, G. B., 2017 Sep 1, In : Microfluidics and Nanofluidics. 21, 9, 145.

Research output: Contribution to journalArticle

Bacteriophages
Biomarkers
Microfluidics
Peptides
peptides
4 Citations (Scopus)

TGFβ promotes mesenchymal phenotype of pancreatic cancer cells, in part, through epigenetic activation of VAV1

Huang, P. H., Lu, P. J., Ding, L. Y., Chu, P. C., Hsu, W. Y., Chen, C. S., Tsao, C. C., Chen, B. H., Lee, C. T., Shan, Y. S. & Chen, C. S., 2017 Apr 20, In : Oncogene. 36, 16, p. 2202-2214 13 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Epigenomics
Phenotype
Epithelial-Mesenchymal Transition
gemcitabine
2 Citations (Scopus)

The regulatory role of aberrant Phosphatase and Tensin Homologue and Liver Kinase B1 on AKT/mTOR/c-Myc axis in pancreatic neuroendocrine tumors

Chang, T. M., Shan, Y. S., Chu, P. Y., Jiang, S. S., Hung, W. C., Chen, Y. L., Tu, H. C., Lin, H. Y., Tsai, H. J. & Chen, L. T., 2017 Jan 1, In : Oncotarget. 8, 58, p. 98068-98083 16 p.

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Sirolimus
Phosphoric Monoester Hydrolases
Phosphotransferases
Liver
14 Citations (Scopus)

The “right” way is not always popular: comparison of surgeons’ perceptions during laparoscopic cholecystectomy for acute cholecystitis among experts from Japan, Korea and Taiwan

Hibi, T., Iwashita, Y., Ohyama, T., Honda, G., Yoshida, M., Takada, T., Han, H. S., Hwang, T. L., Shinya, S., Suzuki, K., Umezawa, A., Yoon, Y. S., Choi, I. S., Huang, W. S. W., Chen, K. H., Miura, F., Watanabe, M., Abe, Y., Misawa, T., Nagakawa, Y. & 42 others, Yoon, D. S., Jang, J. Y., Yu, H. C., Ahn, K. S., Kim, S. C., Song, I. S., Kim, J. H., Yun, S. S., Choi, S. H., Jan, Y. Y., Sheen-Chen, S. M., Shan, Y. S., Ker, C. G., Chan, D. C., Wu, C. C., Toyota, N., Higuchi, R., Nakamura, Y., Mizuguchi, Y., Takeda, Y., Ito, M., Norimizu, S., Yamada, S., Matsumura, N., Shindoh, J., Sunagawa, H., Gocho, T., Hasegawa, H., Rikiyama, T., Sata, N., Kano, N., Kitano, S., Tokumura, H., Yamashita, Y., Watanabe, G., Nakagawa, K., Kimura, T., Yamakawa, T., Wakabayashi, G., Endo, I., Miyazaki, M. & Yamamoto, M., 2017 Jan 1, In : Journal of Hepato-Biliary-Pancreatic Sciences. 24, 1, p. 24-32 9 p.

Research output: Contribution to journalArticle

Acute Cholecystitis
Laparoscopic Cholecystectomy
Korea
Taiwan
Japan
10 Citations (Scopus)

Tumor-associated macrophages promote epigenetic silencing of gelsolin through DNA methyltransferase 1 in gastric cancer cells

Wang, H. C., Chen, C. W., Yang, C. L., Tsai, I. M., Hou, Y. C., Chen, C. J. & Shan, Y-S., 2017 Oct 1, In : Cancer Immunology Research. 5, 10, p. 885-897 13 p.

Research output: Contribution to journalArticle

Gelsolin
Methyltransferases
Epigenomics
Stomach Neoplasms
Macrophages
2016
9 Citations (Scopus)

An increase in galectin-3 causes cellular unresponsiveness to IFN-γ-induced signal transduction and growth inhibition in gastric cancer cells

Tseng, P. C., Chen, C. L., Shan, Y-S. & Lin, C. F., 2016 Mar 22, In : Oncotarget. 7, 12, p. 15150-15160 11 p.

Research output: Contribution to journalArticle

Galectin 3
Interferons
Stomach Neoplasms
Signal Transduction
Glycogen Synthase Kinase 3

An integrated microfluidic platform for screening of aptamers specific to cholangiocarcinoma by utilizing on-chip cell selex process

Gopinathan, P., Hung, L. Y., Wang, C. H., Chiang, N. J., Wang, Y. C., Shan, Y-S. & Lee, G. B., 2016 Jan 1, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 930-931 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Microfluidics
Screening
Biomarkers
Ligands

An integrated microfluidic system for screening of peptides specific to cholangiocarcinoma (CCA) cancer cell lines using the phage display technology

Yu, C. W., Hung, L. Y., Fu, C. Y., Wang, C. H., Chiang, N. J., Wang, Y. C., Shan, Y-S. & Lee, G. B., 2016 Nov 28, 2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2016. Institute of Electrical and Electronics Engineers Inc., p. 561-564 4 p. 7758314. (2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bacteriophages
Microfluidics
Peptides
Screening
Display devices
3 Citations (Scopus)

A phase II study of sequential capecitabine plus oxaliplatin followed by docetaxel plus capecitabine in patients with unresectable gastric adenocarcinoma: The TCOG 3211 clinical trial

Chen, M. H., Lin, J., Hsiao, C. F., Shan, Y-S., Chen, Y. C., Chen, L. T., Liu, T. W., Li, C. P. & Chao, Y., 2016 Jan 1, In : Medicine (United States). 95, 3, e2565.

Research output: Contribution to journalArticle

oxaliplatin
docetaxel
Stomach
Adenocarcinoma
Clinical Trials
5 Citations (Scopus)

Cost effectiveness of cancer treatment in Taiwan

Hung, M. C., Lai, W-W., Chen, H. H. W., Lee, J-C., Lin, Y-J., Hsiao, J-R., Cheng, Y-M., Shan, Y-S., Su, W-C. & Wang, J-D., 2016 Aug 1, In : Journal of the Formosan Medical Association. 115, 8, p. 609-618 10 p.

Research output: Contribution to journalArticle

Taiwan
Cost-Benefit Analysis
Quality-Adjusted Life Years
Gross Domestic Product
Neoplasms
7 Citations (Scopus)

Development of nanoliposomal irinotecan (nal-IRI, MM-398, PEP02) in the management of metastatic pancreatic cancer

Chiang, N. J., Chang, J-Y., Shan, Y-S. & Chen, L. T., 2016 Jul 2, In : Expert Opinion on Pharmacotherapy. 17, 10, p. 1413-1420 8 p.

Research output: Contribution to journalReview article

irinotecan
gemcitabine
Leucovorin
Pancreatic Neoplasms
Fluorouracil
3 Citations (Scopus)

Expression levels of ROS1/ALK/c-MET and therapeutic efficacy of cetuximab plus chemotherapy in advanced biliary tract cancer

Chiang, N. J., Hsu, C., Chen, J. S., Tsou, H. H., Shen, Y. Y., Chao, Y., Chen, M. H., Yeh, T. S., Shan, Y-S., Huang, S. F. & Chen, L. T., 2016 May 3, In : Scientific reports. 6, 25369.

Research output: Contribution to journalArticle

oxaliplatin
gemcitabine
Biliary Tract Neoplasms
Cholangiocarcinoma
Immunohistochemistry
20 Citations (Scopus)

Investigating the Association between Periodontal Disease and Risk of Pancreatic Cancer

Chang, J. S., Tsai, C. R., Chen, L. T. & Shan, Y-S., 2016 Jan 1, In : Pancreas. 45, 1, p. 134-141 8 p.

Research output: Contribution to journalArticle

Periodontal Diseases
Pancreatic Neoplasms
Proxy
Confidence Intervals
Gingivitis
7 Citations (Scopus)

Kit exon 11 codons 557-558 deletion mutation promotes liver metastasis through the CXCL12/ CXCR4 Axis in gastrointestinal stromal tumors

Wang, H. C., Li, T. Y., Chao, Y-J., Hou, Y. C., Hsueh, Y. S., Hsu, K. H. & Shan, Y-S., 2016 Jul 15, In : Clinical Cancer Research. 22, 14, p. 3477-3487 11 p.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Sequence Deletion
Codon
Exons
Stromal Cells
37 Citations (Scopus)

Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells

Chan, T. S., Hsu, C. C., Pai, V. C., Liao, W. Y., Huang, S. S., Tan, K. T., Yen, C-J., Hsu, S. C., Chen, W. Y., Shan, Y-S., Li, C. R., Lee, M. T., Jiang, K. Y., Chu, J. M., Lien, G. S., Weaver, V. M. & Tsai, K. K., 2016 Jan 1, In : Journal of Experimental Medicine. 213, 13, p. 2967-2988 22 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Drug Therapy
Neoplasms
Therapeutics
Chemokines
304 Citations (Scopus)
irinotecan
gemcitabine
Leucovorin
Pancreatic Neoplasms
Fluorouracil

On-chip cholangiocarcinoma cell capture and immunofluorescence staining for clinical diagnosis by using bile juice and whole blood

Hung, L. Y., Tsai, W. C., Fu, C. Y., Chiang, N. J., Wang, Y. C., Shan, Y-S. & Lee, G. B., 2016 Jan 1, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, p. 563-564 2 p. (20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomarkers
Liver
Blood
Microfluidics

Preliminary study of the effectiveness of trauma care system at a medical center in Tainan

Wang, C-J., Yen, S. T., Huang, S. F., Shan, Y-S. & Ying, J. C., 2016 Dec 1, In : Taiwan Journal of Public Health. 35, 6, p. 587-594 8 p.

Research output: Contribution to journalArticle

Injury Severity Score
Wounds and Injuries
Hospital Emergency Service
Torso
Length of Stay
15 Citations (Scopus)

Regulation of oncogenic KRAS signaling via a novel KRAS-integrin-linked kinase-hnRNPA1 regulatory loop in human pancreatic cancer cells

Chu, P. C., Yang, M. C., Kulp, S. K., Salunke, S. B., Himmel, L. E., Fang, C. S., Jadhav, A. M., Shan, Y-S., Lee, C-T., Lai, M-D., Shirley, L. A., Bekaii-Saab, T. & Chen, C. S., 2016 Jul 28, In : Oncogene. 35, 30, p. 3897-3908 12 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Small Interfering RNA
integrin-linked kinase
Heterogeneous-Nuclear Ribonucleoproteins
G-Quadruplexes