Projects per year
Personal profile
Education
德國Technische Universit?t Dortmu 化學暨化學生物學系 博士
Research Interests
有機化學、化學生物學
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Dive into the research topics where Yen-Chun Lee is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Projects
- 1 Finished
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Mirror-image ligand discovery enabled by single-shot fast-flow synthesis of D-proteins
Callahan, A. J., Gandhesiri, S., Travaline, T. L., Reja, R. M., Lozano Salazar, L., Hanna, S., Lee, Y. C., Li, K., Tokareva, O. S., Swiecicki, J. M., Loas, A., Verdine, G. L., McGee, J. H. & Pentelute, B. L., 2024 Dec, In: Nature communications. 15, 1, 1813.Research output: Contribution to journal › Article › peer-review
Open Access16 Citations (Scopus) -
A Pt(IV)-conjugated brain penetrant macrocyclic peptide shows pre-clinical efficacy in glioblastoma
Jimenez-Macias, J. L., Lee, Y. C., Miller, E., Finkelberg, T., Zdioruk, M., Berger, G., Farquhar, C. E., Nowicki, M. O., Cho, C. F., Fedeles, B. I., Loas, A., Pentelute, B. L. & Lawler, S. E., 2022 Dec, In: Journal of Controlled Release. 352, p. 623-636 14 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus) -
Binary combinatorial scanning reveals potent poly-alanine-substituted inhibitors of protein-protein interactions
Ye, X., Lee, Y. C., Gates, Z. P., Ling, Y., Mortensen, J. C., Yang, F. S., Lin, Y. S. & Pentelute, B. L., 2022 Dec, In: Communications Chemistry. 5, 1, 128.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein
Pomplun, S., Jbara, M., Quartararo, A. J., Zhang, G., Brown, J. S., Lee, Y. C., Ye, X., Hanna, S. & Pentelute, B. L., 2021 Jan 27, In: ACS Central Science. 7, 1, p. 156-163 8 p.Research output: Contribution to journal › Article › peer-review
Open Access70 Citations (Scopus) -
A Platinum(IV) Prodrug - Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain
Fadzen, C. M., Wolfe, J. M., Zhou, W., Cho, C. F., Von Spreckelsen, N., Hutchinson, K. T., Lee, Y. C., Chiocca, E. A., Lawler, S. E., Yilmaz, O. H., Lippard, S. J. & Pentelute, B. L., 2020 Jul 9, In: Journal of Medicinal Chemistry. 63, 13, p. 6741-6747 7 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Citations (Scopus)