Projects per year
Personal profile
Education
- 1993 PhD,Department of Genetics, Michigan State University
Experience
- 1995~1999 Associate Professor, Institute of Toxicology, Chung Shan Medical Univ., Taichung, Taiwan
- 1999~2006 Professor, Department of Life Science, National Taiwan Normal Univ., Taipei, Taiwan
- 2006~2015 Distinguished Professor, Department of Pharmacology, National Cheng Kung University, Tainan, Taiwan
- 2015~now Chair Professor, Department of Pharmacology & Institute of Basic Medical Science & Institute of Clinical Medical Science, National Cheng Kung University, Tainan, Taiwan
Research Interests
- Molecular cancer biology
- Cancer epigenetics
- Transcription deregulation in cancer
- Vesicle trafficking in tumor microenvironment
- Anticancer drug development
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger
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SDG 3 Good Health and Well-being
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SDG 7 Affordable and Clean Energy
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SDG 9 Industry, Innovation, and Infrastructure
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Collaborations and top research areas from the last five years
Projects
- 40 Finished
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食道癌化放療抗性之轉錄體機制研究及臨床應用分析-NRF2轉錄成癮導致食道癌化放療抗性之機轉研究及臨床驗證( II )
Wang, Y.-C. (PI)
21-08-01 → 22-07-31
Project: Research project
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開發抗 Chitinase 3-like 1 的全人源抗體以應用於癌症免疫治療( I )
Wang, Y.-C. (PI)
21-06-01 → 22-05-31
Project: Research project
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浸潤免疫細胞之Rab37與癌細胞之WDR4協同調控腫瘤微環境中逃避免疫攻擊的機制
Wang, Y.-C. (PI)
20-08-01 → 21-07-31
Project: Research project
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Post-translational modifications of immune checkpoints: molecular mechanisms, tumor microenvironment remodeling, and therapeutic implications
Hsieh, H. C., Ling, L. L. & Wang, Y. C., 2026 Dec, In: Journal of biomedical science. 33, 1, 3.Research output: Contribution to journal › Review article › peer-review
Open Access9 Link opens in a new tab Citations (Scopus) -
Rab37-mediated OPN secretion enriches SPP1+ macrophages through autocrine–paracrine signaling to drive lung tumor progression
Yang, Y. E., Lin, Y. A., Ling, L. L., Kuo, I.-Y., Kuo, W. T., Liu, H. & Wang, Y. C., 2026 Dec, In: Oncogenesis. 15, 1, 4.Research output: Contribution to journal › Article › peer-review
Open Access -
Deubiquitinase USP24 activated by IL-6/STAT3 enhances PD-1 protein stability and suppresses T cell antitumor response
Hsieh, H. C., Young, M. J., Chen, K. Y., Su, W. C., Lin, C. C., Yen, Y. T., Hung, J. J. & Wang, Y. C., 2025 Apr 18, In: Science Advances. 11, 16, eadt4258.Research output: Contribution to journal › Article › peer-review
Open Access17 Link opens in a new tab Citations (Scopus) -
GDP-bound Rab37 modulates M2-like tumor-associated macrophage polarization by attenuating STAT1 translocation to downregulate the type I IFN pathway: Cellular and Molecular Biology
Hong, C. T., Yang, Y. E., Juan, H. F., Chang, C. P. & Wang, Y. C., 2025 Apr 20, In: British Journal of Cancer. 132, 7, p. 622-634 13 p., 3928.Research output: Contribution to journal › Article › peer-review
1 Link opens in a new tab Citation (Scopus) -
Macrophage activation determines muscle wasting in pancreatic cancer
Chang, C. J., Huang, P. H., Chen, S. Y., Su, P. C., Ding, L. Y., Hou, Y. C., Hung, M. N., Chen, K. L., Wu, Y. N., Wu, S. R., Lin, F. C., Lu, P. J., Wu, H. Y., Chen, Y. J., Chang, C. H., Chang, C. P., Hwang, D. Y., Wang, Y. C. & Shan, Y. S., 2025 Aug 25, In: Oncogene. 44, 32, p. 2797-2813 17 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Link opens in a new tab Citations (Scopus)