• 13573 Citations
  • 49 h-Index
19942019

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Article
2011

Lipoic acid ameliorates arsenic trioxide-induced HO-1 expression and oxidative stress in THP-1 monocytes and macrophages

Wang, L., Weng, C. Y., Wang, Y. J. & Wu, M. J., 2011 Apr 25, In : Chemico-Biological Interactions. 190, 2-3, p. 129-138 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins

Chen, C. S., Lee, C. H., Hsieh, C. D., Ho, C. T., Pan, M. H., Huang, C. S., Tu, S. H., Wang, Y. J., Chen, L. C., Chang, Y. J., Wei, P. L., Yang, Y. Y., Wu, C. H. & Ho, Y. S., 2011 Jan 1, In : Breast Cancer Research and Treatment. 125, 1, p. 73-87 15 p.

Research output: Contribution to journalArticle

83 Citations (Scopus)

Occupational hand dermatitis among cement workers in Taiwan

Wang, B. J., Wu, J. D., Sheu, S. C., Shih, T. S., Chang, H. Y., Guo, Y. L., Wang, Y. J. & Chou, T. C., 2011 Dec 1, In : Journal of the Formosan Medical Association. 110, 12, p. 775-779 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Prediction of atopic dermatitis in 2-yr-old children by cord blood IgE, genetic polymorphisms in cytokine genes, and maternal mentality during pregnancy

Wen, H. J., Wang, Y-J., Lin, Y. C., Chang, C-C., Shieh, C-C., Lung, F. W. & Guo, Y. L., 2011 Nov, In : Pediatric Allergy and Immunology. 22, 7, p. 695-703 9 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
28 Citations (Scopus)

Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathway

Chiou, Y. S., Tsai, M. L., Nagabhushanam, K., Wang, Y. J., Wu, C. H., Ho, C. T. & Pan, M. H., 2011 Mar 23, In : Journal of Agricultural and Food Chemistry. 59, 6, p. 2725-2733 9 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

Synergism between 2,3,7,8-tetrachlorodibenzo-p-dioxin and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone on lung tumor incidence in mice

Wang, Y. J., Chang, H., Kuo, Y. C., Wang, C. K., Siao, S. H., Chang, L. W. & Lin, P., 2011 Feb 15, In : Journal of Hazardous Materials. 186, 1, p. 869-875 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Synergistic effects of arsenic trioxide and radiation in osteosarcoma cells through the induction of both autophagy and apoptosis

Chiu, H. W., Lin, W., Ho, S. Y. & Wang, Y-J., 2011 May 1, In : Radiation Research. 175, 5, p. 547-560 14 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

α-Lipoic acid inhibits liver fibrosis through the attenuation of ROS-triggered signaling in hepatic stellate cells activated by PDGF and TGF-β

Foo, N. P., Lin, S. H., Lee, Y. H., Wu, M. J. & Wang, Y. J., 2011 Mar 28, In : Toxicology. 282, 1-2, p. 39-46 8 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)
2010

Hexavalent chromium induced ROS formation, Akt, NF-κB, and MAPK activation, and TNF-α and IL-1α production in keratinocytes

Wang, B. J., Sheu, H. M., Guo, Y. L., Lee, Y. H., Lai, C. S., Pan, M. H. & Wang, Y. J., 2010 Oct 1, In : Toxicology Letters. 198, 2, p. 216-224 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Increased expression of enolase α in human breast cancer confers tamoxifen resistance in human breast cancer cells

Tu, S. H., Chang, C. C., Chen, C. S., Tam, K. W., Wang, Y. J., Lee, C. H., Lin, H. W., Cheng, T. C., Huang, C. S., Chu, J. S., Shih, N. Y., Chen, L. C., Leu, S. J., Ho, Y. S. & Wu, C. H., 2010 Jun 1, In : Breast Cancer Research and Treatment. 121, 3, p. 539-553 15 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Long-term ethanol exposure causes human liver cancer cells to become resistant to mitomycin c treatment through the inactivation of bad-mediated apoptosis

Huang, C. S., Lee, Y. R., Chen, C. S., Tu, S. H., Wang, Y. J., Lee, C. H., Chen, L. C., Chang, H. W., Chang, C. H., Chih-Ming, S., Wu, C. H. & Ho, Y. S., 2010 Aug, In : Molecular Carcinogenesis. 49, 8, p. 728-738 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
55 Citations (Scopus)

N-acetylcysteine inhibits chromium hypersensitivity in coadjuvant chromium-sensitized albino guinea pigs by suppressing the effects of reactive oxygen species

Wang, B. J., Guo, Y. L., Chang, H. Y., Sheu, H. M., Pan, M. H., Lee, Y. H. & Wang, Y. J., 2010 Aug 1, In : Experimental Dermatology. 19, 8, p. e191-e200

Research output: Contribution to journalArticle

16 Citations (Scopus)

Overexpression and activation of the α9-nicotinic receptor during tumorigenesis in human breast epithelial cells

Lee, C. H., Huang, C. S., Chen, C. S., Tu, S. H., Wang, Y. J., Chang, Y. J., Tam, K. W., Wei, P. L., Cheng, T. C., Chu, J. S., Chen, L. C., Wu, C. H. & Ho, Y. S., 2010 Sep 8, In : Journal of the National Cancer Institute. 102, 17, p. 1322-1335 14 p.

Research output: Contribution to journalArticle

105 Citations (Scopus)

Pterostilbene induces autophagy and apoptosis in sensitive and chemoresistant human bladder cancer cells

Chen, R. J., Ho, C. T. & Wang, Y. J., 2010 Dec 1, In : Molecular Nutrition and Food Research. 54, 12, p. 1819-1832 14 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Pterostilbene inhibits colorectal aberrant crypt foci (ACF) and colon carcinogenesis via suppression of multiple signal transduction pathways in azoxymethane-treated mice

Chiou, Y. S., Tsai, M. L., Wang, Y-J., Cheng, A. C., Lai, W. M., Badmaev, V., Ho, C. T. & Pan, M. H., 2010 Aug 11, In : Journal of Agricultural and Food Chemistry. 58, 15, p. 8833-8841 9 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2009

Apple polyphenol phloretin potentiates the anticancer actions of paclitaxel through induction of apoptosis in human Hep G2 cells

Yang, K. C., Tsai, C. Y., Wang, Y. J., Wei, P. L., Lee, C. H., Chen, J. H., Wu, C. H. & Ho, Y. S., 2009 May 1, In : Molecular Carcinogenesis. 48, 5, p. 420-431 12 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Carbonyl compounds and toxicity assessments of emissions from a diesel engine running on biodiesels

Liu, Y. Y., Lin, T. C., Wang, Y. J. & Ho, W. L., 2009 Feb, In : Journal of the Air and Waste Management Association. 59, 2, p. 163-171 9 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Combination treatment with arsenic trioxide and irradiation enhances apoptotic effects in U937 cells through increased mitotic arrest and ROS generation

Ho, S. Y., Chen, W. C., Chiu, H. W., Lai, C. S., Guo, H. R. & Wang, Y. J., 2009 May 15, In : Chemico-Biological Interactions. 179, 2-3, p. 304-313 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
83 Citations (Scopus)

EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells

Huang, C. H., Tsai, S. J., Wang, Y. J., Pan, M. H., Kao, J. Y. & Way, T. D., 2009 Oct 9, In : Molecular Nutrition and Food Research. 53, 9, p. 1156-1165 10 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Inhibitory effects of chitooligosaccharides on tumor growth and metastasis

Shen, K. T., Chen, M. H., Chan, H. Y., Jeng, J. H. & Wang, Y. J., 2009 Aug 1, In : Food and Chemical Toxicology. 47, 8, p. 1864-1871 8 p.

Research output: Contribution to journalArticle

132 Citations (Scopus)

In vitro and in vivo study of phloretin-induced apoptosis in human liver cancer cells involving inhibition of type II glucose transporter

Wu, C. H., Ho, Y. S., Tsai, C. Y., Wang, Y-J., Tseng, H., Wei, P. L., Lee, C. H., Liu, R. S. & Lin, S. Y., 2009 May 1, In : International Journal of Cancer. 124, 9, p. 2210-2219 10 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Protective role of estrogen receptor-alpha on lower chlorinated PCB congener-induced DNA damage and repair in human tumoral breast cells

Lin, C. H., Huang, C. L., Chuang, M. C., Wang, Y. J., Chen, D. R., Chen, S. T. & Lin, P. H., 2009 Jul 10, In : Toxicology Letters. 188, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Rosmanol potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-κB, STAT3 and C/EBP signaling pathways

Lai, C. S., Lee, J. H., Ho, C. T., Liu, C. B., Wang, J-M., Wang, Y-J. & Pan, M. H., 2009 Nov 25, In : Journal of Agricultural and Food Chemistry. 57, 22, p. 10990-10998 9 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Signaling pathways for induction of platelet aggregation by sas tongue cancer cells - A mechanism of hematogenous metastasis

Chang, M. C., Chan, C. P., Ho, Y. S., Lee, J. J., Lin, P. S., Lin, B. R., Huang, Y. L., Hahn, L. J., Yeh, H. W., Wang, Y. J. & Jeng, J. H., 2009 May 1, In : Journal of Oral Pathology and Medicine. 38, 5, p. 434-440 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2008

Anti-inflammatory and antitumor promotional effects of a novel urinary metabolite, 3′,4′-didemethylnobiletin, derived from nobiletin

Lai, C. S., Li, S., Chai, C. Y., Lo, C. Y., Dushenkov, S., Ho, C. T., Pan, M. H. & Wang, Y-J., 2008 Dec 15, In : Carcinogenesis. 29, 12, p. 2415-2424 10 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Antitumor activity of 3,5,4′-trimethoxystilbene in COLO 205 cells and xenografts in SCID mice

Pan, M. H., Gao, J. H., Lai, C. S., Wang, Y. J., Chen, W. M., Lo, C. Y., Wang, M., Dushenkov, S. & Ho, C. T., 2008 Mar 1, In : Molecular Carcinogenesis. 47, 3, p. 184-196 13 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)
20 Citations (Scopus)

Dihydrolipoic acid inhibits tetrachlorohydroquinone-induced tumor promotion through prevention of oxidative damage

Wang, Y. J., Yang, M. C. & Pan, M. H., 2008 Dec 1, In : Food and Chemical Toxicology. 46, 12, p. 3739-3748 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Effects of fungal-derived high molecular weight chitosan on 5-fluorouracil-induced adverse reactions

Uen, Y. H., Wang, Y. J., Hsu, T. M., Chen, M. H., Chan, H. Y., Ho, Y. S. & Lin, S. Y., 2008 Sep 1, In : Journal of Bioactive and Compatible Polymers. 23, 5, p. 458-472 15 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Exposure to a mixture of Polychlorinated biphenyls and polychlorinated dibenzofurans resulted in a prolonged time to pregnancy in women

Yang, C. Y., Wang, Y. J., Chen, P. C., Tsai, S. J. & Guo, Y. L., 2008 May, In : Environmental Health Perspectives. 116, 5, p. 599-604 6 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

NF-κB-activated tissue transglutaminase is involved in ethanol-induced hepatic injury and the possible role of propolis in preventing fibrogenesis

Chen, C. S., Wu, C. H., Lai, Y. C., Lee, W. S., Chen, H. M., Chen, R. J., Chen, L. C., Ho, Y. S. & Wang, Y. J., 2008 Apr 18, In : Toxicology. 246, 2-3, p. 148-157 10 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells

Chen, R. J., Ho, Y. S., Guo, H. R. & Wang, Y. J., 2008 Aug 1, In : Toxicological Sciences. 104, 2, p. 283-293 11 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Reduced expression of von Hippel-Lindau gene in subjects exposed to polychlorinated biphenyls and dibenzofurans

Tsai, P. C., Wang, Y-J., Tsai, J. H., Guo, Y. L., Ueng, T. H., Liu, H-S. & Huang, W-Y., 2008 Oct 1, In : Environmental Research. 108, 2, p. 247-251 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

SP1-regulated p27/Kip1 gene expression is involved in terbinafine-induced human A431 cancer cell differentiation: An in vitro and in vivo study

Huang, C. S., Ho, W. L., Lee, W. S., Sheu, M. T., Wang, Y. J., Tu, S. H., Chen, R. J., Chu, J. S., Chen, L. C., Lee, C. H., Tseng, H., Ho, Y. S. & Wu, C. H., 2008 May 1, In : Biochemical Pharmacology. 75, 9, p. 1783-1796 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Thrombin activates Ras-CREB/ATF-1 signaling and stimulates c-fos, c-jun, and c-myc expression in human gingival fibroblasts

Chan, C. P., Chang, M. C., Wang, Y-J., Chen, L. I., Tsai, Y. L., Lee, J. J., Jia, H. W. & Jeng, J. H., 2008 Jul 1, In : Journal of periodontology. 79, 7, p. 1248-1254 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2007

5-Hydroxy-3,6,7,8,3′,4′-hexamethoxyflavone induces apoptosis through reactive oxygen species production, growth arrest and DNA damage-inducible gene 153 expression, and caspase activation in human leukemia cells

Pan, M. H., Lai, Y. S., Lai, C. S., Wang, Y. J., Li, S., Lo, C. Y., Dushenkov, S. & Ho, C. T., 2007 Jun 27, In : Journal of Agricultural and Food Chemistry. 55, 13, p. 5081-5091 11 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Antiplatelet effect of sanguinarine is correlated to calcium mobilization, thromboxane and cAMP production

Jeng, J. H., Wu, H. L., Lin, B. R., Lan, W. H., Chang, H. H., Ho, Y. S., Lee, P. H., Wang, Y. J., Wang, J. S., Chen, Y. J. & Chang, M. C., 2007 Apr 1, In : Atherosclerosis. 191, 2, p. 250-258 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Chitosan prevents the development of AOM-induced aberrant crypt foci in mice and suppressed the proliferation of AGS cells by inhibiting DNA synthesis

Lin, S. Y., Chan, H. Y., Shen, F. H., Chen, M. H., Wang, Y-J. & Yu, C-K., 2007 Apr 15, In : Journal of Cellular Biochemistry. 100, 6, p. 1573-1580 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Dihydrolipoic acid inhibits skin tumor promotion through anti-inflammation and anti-oxidation

Ho, Y. S., Lai, C. S., Liu, H. I., Ho, S. Y., Tai, C., Pan, M. H. & Wang, Y. J., 2007 Jun 1, In : Biochemical Pharmacology. 73, 11, p. 1786-1795 10 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)
18 Citations (Scopus)

Induction of necrosis and apoptosis to KB cancer cells by sanguinarine is associated with reactive oxygen species production and mitochondrial membrane depolarization

Chang, M. C., Chan, C. P., Wang, Y. J., Lee, P. H., Chen, L. I., Tsai, Y. L., Lin, B. R., Wang, Y. L. & Jeng, J. H., 2007 Jan 15, In : Toxicology and Applied Pharmacology. 218, 2, p. 143-151 9 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Inhibitory effect of citrus 5-hydroxy-3,6,7,8,3′,4′-hexamethoxyflavone on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice

Lai, C. S., Li, S., Chai, C. Y., Lo, C. Y., Ho, C. T., Wang, Y. J. & Pan, M. H., 2007 Dec 1, In : Carcinogenesis. 28, 12, p. 2581-2588 8 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Protection against arsenic trioxide-induced autophagic cell death in U118 human glioma cells by use of lipoic acid

Cheng, T. J., Wang, Y. J., Kao, W. W., Chen, R. J. & Ho, Y. S., 2007 Jun 1, In : Food and Chemical Toxicology. 45, 6, p. 1027-1038 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2006

Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice

Pan, M. H., Lai, C. S., Wang, Y. J. & Ho, C. T., 2006 Nov 15, In : Biochemical Pharmacology. 72, 10, p. 1293-1303 11 p.

Research output: Contribution to journalArticle

107 Citations (Scopus)
16 Citations (Scopus)
2 Citations (Scopus)

Involvement of proapoptotic Bcl-2 family members in terbinafine-induced mitochondrial dysfunction and apoptosis in HL60 cells

Yang, K. C., Wu, C. C., Wu, C. H., Chen, J. H., Chu, C. H., Chen, C. H., Chou, Y. H., Wang, Y. J., Lee, W. S., Tseng, H., Lin, S. Y., Lee, C. H. & Ho, Y. S., 2006 Feb 1, In : Food and Chemical Toxicology. 44, 2, p. 214-226 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)