• 455 Citations
  • 12 h-Index
20062019
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Research Output 2006 2019

  • 455 Citations
  • 12 h-Index
  • 31 Article
  • 1 Letter
  • 1 Review article
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Article
2019

A new histone deacetylase inhibitor enhances radiation sensitivity through the induction of misfolded protein aggregation and autophagy in triple-negative breast cancer

Chiu, H. W., Yeh, Y. L., Ho, S. Y., Wu, Y. H., Wang, B. J., Huang, W. J., Ho, Y. S., Wang, Y. J., Chen, L. C. & Tu, S. H., 2019 Nov, In : Cancers. 11, 11, 1703.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Radiation Tolerance
Autophagy
Proteins

Cordycepin enhances radiosensitivity in oral squamous carcinoma cells by inducing autophagy and apoptosis through cell cycle arrest

Ho, S. Y., Wu, W. S., Lin, L. C., Wu, Y. H., Chiu, H. W., Yeh, Y. L., Huang, B. M. & Wang, Y. J., 2019 Nov 1, In : International journal of molecular sciences. 20, 21, 5366.

Research output: Contribution to journalArticle

Open Access
Radiation Tolerance
Autophagy
apoptosis
Cell death
radiation tolerance

Oral hygiene and the overall survival of head and neck cancer patients

Chang, C. C., Lee, W. T., Hsiao, J. R., Ou, C. Y., Huang, C. C., Tsai, S. T., Chen, K. C., Huang, J. S., Wong, T. Y., Lai, Y. H., Wu, Y. H., Hsueh, W. T., Wu, S. Y., Yen, C. J., Chang, J. Y., Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2019 Apr, In : Cancer medicine. 8, 4, p. 1854-1864 11 p.

Research output: Contribution to journalArticle

Open Access
Oral Hygiene
Head and Neck Neoplasms
Survival
Confidence Intervals
Tooth
Head and Neck Neoplasms
Alcohol Drinking
Ethanol
Survival
Genes
Open Access
Hypopharyngeal Neoplasms
Chemoradiotherapy
Neutrophils
Lymphocytes
Serum
2018
3 Citations (Scopus)

Adjuvant radiotherapy after curative surgery for oral cavity squamous cell carcinoma and treatment effect of timing and duration on outcome—A Taiwan Cancer Registry national database analysis

Cheng, Y. J., Tsai, M. H., Chiang, C. J., Tsai, S. T., Liu, T. W., Lou, P. J., Liao, C. T., Lin, J. C., Chang, J. T. C., Tsai, M. H., Chu, P. Y., Leu, Y. S., Tsai, K. Y., Terng, S. D., Chien, C. Y., Yang, M. H., Hao, S. P., Wang, C. C., Tsai, M. H., Chen, H. H. W. & 2 others, Kuo, C. & Wu, Y. H., 2018 Jul, In : Cancer medicine. 7, 7, p. 3073-3083 11 p.

Research output: Contribution to journalArticle

Adjuvant Radiotherapy
Taiwan
Registries
Mouth
Squamous Cell Carcinoma
5 Citations (Scopus)

Bortezomib enhances radiosensitivity in oral cancer through inducing autophagy-mediated TRAF6 oncoprotein degradation

Wu, Y. H., Wu, W. S., Lin, L. C., Liu, C. S., Ho, S. Y., Wang, B. J., Huang, B. M., Yeh, Y. L., Chiu, H. W., Yang, W. L. & Wang, Y. J., 2018 Apr 27, In : Journal of Experimental and Clinical Cancer Research. 37, 1, 91.

Research output: Contribution to journalArticle

Tumor Necrosis Factor Receptor-Associated Peptides and Proteins
Mouth Neoplasms
Radiation Tolerance
Oncogene Proteins
Autophagy
7 Citations (Scopus)

The interplay between oral microbiome, lifestyle factors and genetic polymorphisms in the risk of oral squamous cell carcinoma

Hsiao, J-R., Chang, C-C., Lee, W-T., Huang, C-C., Ou, C-Y., Tsai, S-T., Chen, K-C., Huang, J-S., Wang, D-Y., Lai, Y-H., Wu, Y-H., Hsueh, W-T., Wu, S-Y., Yen, C-J., Chang, J-Y., Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2018 May 28, In : Carcinogenesis. 39, 6, p. 778-787 10 p.

Research output: Contribution to journalArticle

Microbiota
Genetic Polymorphisms
Life Style
Squamous Cell Carcinoma
Oral Hygiene
2017
6 Citations (Scopus)

A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer

Wu, Y. H., Hong, C. W., Wang, Y. C., Huang, W. J., Yeh, Y. L., Wang, B. J., Wang, Y. J. & Chiu, H. W., 2017 Aug 1, In : Cancer Letters. 400, p. 79-88 10 p.

Research output: Contribution to journalArticle

DNA-Activated Protein Kinase
Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Etoposide
DNA Repair
12 Citations (Scopus)

Investigating the Association between Alcohol and Risk of Head and Neck Cancer in Taiwan

Huang, C. C., Hsiao, J. R., Lee, W. T., Lee, Y. C., Ou, C. Y., Chang, C. C., Lu, Y. C., Huang, J. S., Wong, T. Y., Chen, K. C., Tsai, S. T., Fang, S. Y., Wu, J. L., Wu, Y. H., Hsueh, W. T., Yen, C. J., Wu, S. Y., Chang, J. Y., Lin, C. L., Wang, Y. H. & 4 others, Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 Dec 1, In : Scientific reports. 7, 1, 9701.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Taiwan
Alcohols
Hypopharyngeal Neoplasms
Oropharyngeal Neoplasms
5 Citations (Scopus)

Investigating the association between diet and risk of head and neck cancer in Taiwan

Chang, C. C., Lee, W. T., Lee, Y. C., Huang, C. C., Ou, C. Y., Lin, Y. H., Huang, J. S., Wong, T. Y., Chen, K. C., Hsiao, J. R., Lu, Y. C., Tsai, S. T., Lai, Y. H., Wu, Y. H., Hsueh, W. T., Yen, C. J., Wu, S. Y., Chang, J. Y., Fang, S. Y., Wu, J. L. & 5 others, Lin, C. L., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 Jan 1, In : Oncotarget. 8, 58, p. 98865-98875 11 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Taiwan
Vegetables
Diet
Fruit

Regular recreational physical activity and risk of head and neck cancer

Lin, C. L., Lee, W. T., Ou, C. Y., Hsiao, J. R., Huang, C. C., Huang, J. S., Wong, T. Y., Chen, K. C., Tsai, S. T., Fang, S. Y., Huang, T. T., Wu, J. L., Wu, Y. H., Hsueh, W. T., Yen, C. J., Lai, Y. H., Liao, H. C., Wu, S. Y., Yang, M. W., Lin, F. C. & 6 others, Chang, J. Y., Wang, Y. H., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2017 Apr 21, In : BMC cancer. 17, 1, 286.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Tobacco Products
Vegetables
Fruit
Logistic Models
2016
8 Citations (Scopus)

A comprehensive analysis on the association between tobacco-free betel quid and risk of head and neck cancer in Taiwanese men

Wu, Y. H., Yen, C. J., Hsiao, J. R., Ou, C. Y., Huang, J. S., Wong, T. Y., Tsai, S. T., Huang, C. C., Lee, W. T., Chen, K. C., Fang, S. Y., Wu, J. L., Hsueh, W. T., Lin, F. C., Yang, M. W., Chang, J. Y., Liao, H. C., Wu, S. Y., Lin, C. L., Wang, Y. H. & 4 others, Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2016 Oct, In : PloS one. 11, 10, 0164937.

Research output: Contribution to journalArticle

betel
Tobacco
Head and Neck Neoplasms
Mastication
tobacco
2 Citations (Scopus)

Allergy symptoms, serum total immunoglobulin E, and risk of head and neck cancer

Liao, H. C., Wu, S-Y., Ou, C-Y., Hsiao, J-R., Huang, J-S., Tsai, S-T., Huang, C-C., Wang, D-Y., Lee, W-T., Chen, K-C., Fang, S-Y., Wu, J-L., Huang, T-T., Wu, Y-H., Hsueh, W-T., Yen, C-J., Yang, M-W., Lin, F-C., Lai, Y-H., Chang, J-Y. & 6 others, Lin, C. L., Wang, Y. H., Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2016 Sep 1, In : Cancer Causes and Control. 27, 9, p. 1105-1115 11 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Immunoglobulin E
Hypersensitivity
Serum
Odds Ratio
2015
4 Citations (Scopus)

Alcohol drinking obliterates the inverse association between serum retinol and risk of head and neck cancer

Chen, K. C., Hsueh, W. T., Ou, C. Y., Huang, C. C., Lee, W. T., Fang, S. Y., Tsai, S. T., Huang, J. S., Wong, T. Y., Wu, J. L., Yen, C. J., Wu, Y. H., Lin, F. C., Yang, M. W., Chang, J. Y., Liao, H. C., Wu, S. Y., Hsiao, J. R., Lin, C. L., Wang, Y. H. & 4 others, Weng, Y. L., Yang, H. C., Chen, Y. S. & Chang, J. S., 2015 Jul 1, In : Medicine (United States). 94, 26, e1064.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Vitamin A
Alcohol Drinking
Serum
Alcohols
1 Citation (Scopus)

Genetic polymorphisms in the prostaglandin pathway genes and risk of head and neck cancer

Lee, W-T., Huang, C-C., Chen, K-C., Wang, D-Y., Ou, C-Y., Tsai, S-T., Yen, C-J., Fang, S-Y., Lo, H. I., Wu, Y-H., Hsueh, W-T., Yang, M-W., Lin, F-C., Hsiao, J-R., Huang, J-S., Chang, J-Y., Chang, K. Y., Wu, S-Y., Lin, C. L., Wang, Y. H. & 3 others, Weng, Y. L., Yang, H. C. & Chang, JS. S., 2015 Mar 1, In : Oral Diseases. 21, 2, p. 207-215 9 p.

Research output: Contribution to journalArticle

Genetic Polymorphisms
Head and Neck Neoplasms
Prostaglandins
Genes
Odds Ratio
21 Citations (Scopus)

Synergistic antitumor effects of radiation and proteasome inhibitor treatment in pancreatic cancer through the induction of autophagy and the downregulation of TRAF6

Chiu, H. W., Lin, S. W., Lin, L. C., Hsu, Y. H., Lin, Y. F., Ho, S. Y., Wu, Y-H. & Wang, Y-J., 2015 Sep 1, In : Cancer Letters. 365, 2, p. 229-239 11 p.

Research output: Contribution to journalArticle

TNF Receptor-Associated Factor 6
Proteasome Inhibitors
Radiation Effects
Autophagy
Pancreatic Neoplasms
2014
68 Citations (Scopus)

COL11A1 promotes tumor progression and predicts poor clinical outcome in ovarian cancer

Wu, Y. H., Chang, T. H., Huang, Y. F., Huang, H. D. & Chou, C. Y., 2014 Jun 26, In : Oncogene. 33, 26, p. 3432-3440 9 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Transforming Growth Factors
Neoplasms
Disease Progression
Collagen Type XI
15 Citations (Scopus)
Chemoradiotherapy
Radiation
Drug Therapy
Cisplatin
Disease-Free Survival
10 Citations (Scopus)

Tea consumption and risk of head and neck cancer

Huang, C. C., Lee, W. T., Tsai, S. T., Ou, C. Y., Lo, H. I., Wong, T. Y., Fang, S. Y., Chen, K. C., Huang, J. S., Wu, J. L., Yen, C. J., Hsueh, W. T., Wu, Y. H., Yang, M. W., Lin, F. C., Chang, J. Y., Chang, K. Y., Wu, S. Y., Hsiao, J. R., Lin, C. L. & 4 others, Wang, Y. H., Weng, Y. L., Yang, H. C. & Chang, J. S., 2014 May 5, In : PloS one. 9, 5, e96507.

Research output: Contribution to journalArticle

tea (beverage)
Tea
Head and Neck Neoplasms
odds ratio
confidence interval
32 Citations (Scopus)

The interplay between alcohol consumption, oral hygiene, ALDH2and ADH1B in the risk of head and neck cancer

Tsai, S. T., Wong, T. Y., Ou, C. Y., Fang, S. Y., Chen, K. C., Hsiao, J. R., Huang, C. C., Lee, W. T., Lo, H. I., Huang, J. S., Wu, J. L., Yen, C. J., Hsueh, W. T., Wu, Y. H., Yang, M. W., Lin, F. C., Chang, J. Y., Chang, K. Y., Wu, S. Y., Liao, H. C. & 5 others, Lin, C. L., Wang, Y. H., Weng, Y. L., Yang, H. C. & Chang, J. S., 2014 Nov 15, In : International Journal of Cancer. 135, 10, p. 2424-2436 13 p.

Research output: Contribution to journalArticle

Oral Hygiene
Head and Neck Neoplasms
Alcohol Drinking
Genotype
Acetaldehyde
2013
14 Citations (Scopus)

Allergies and Risk of Head and Neck Cancer: An Original Study plus Meta-Analysis

Hsiao, J. R., Ou, C. Y., Lo, H. I., Huang, C. C., Lee, W. T., Huang, J. S., Chen, K. C., Wong, T. Y., Tsai, S. T., Yen, C. J., Wu, Y. H., Hsueh, W. T., Yang, M. W., Wu, S. Y., Chang, J. Y., Chang, K. Y., Lin, C. L., Wang, F. T., Wang, Y. H., Weng, Y. L. & 2 others, Yang, H. C. & Chang, J. S., 2013 Feb 1, In : PloS one. 8, 2, e55138.

Research output: Contribution to journalArticle

Allergies
Head and Neck Neoplasms
meta-analysis
hypersensitivity
Meta-Analysis
48 Citations (Scopus)

Investigating the association between oral hygiene and head and neck cancer

Chang, J. S., Lo, H. I., Wong, T. Y., Huang, C. C., Lee, W. T., Tsai, S. T., Chen, K. C., Yen, C. J., Wu, Y. H., Hsueh, W. T., Yang, M. W., Wu, S. Y., Chang, K. Y., Chang, J. Y., Ou, C. Y., Wang, Y. H., Weng, Y. L., Yang, H. C., Wang, F. T., Lin, C. L. & 2 others, Huang, J. S. & Hsiao, J. R., 2013 Oct 1, In : Oral Oncology. 49, 10, p. 1010-1017 8 p.

Research output: Contribution to journalArticle

Oral Hygiene
Head and Neck Neoplasms
Dental Care
Tooth
Tobacco Products
6 Citations (Scopus)
Doppler Ultrasonography
Radiotherapy
Carcinoma
Recurrence
Biomarkers
2012
5 Citations (Scopus)
Rectal Neoplasms
Tomography
Carcinoma
Neoplasms
Therapeutics
6 Citations (Scopus)
Uterine Cervical Neoplasms
radiation therapy
Radiotherapy
cancer
activation
16 Citations (Scopus)
Intensity-Modulated Radiotherapy
Mouth
Squamous Cell Carcinoma
Radiotherapy
Survival Rate
2011
13 Citations (Scopus)

Human papilloma virus detection in neoplastic and non-neoplastic nasopharyngeal tissues in Taiwan

Huang, C-C., Hsiao, J-R., Yang, M-W., Wu, Y-H., Hsu, K-F., Chang, Y., Chen, C. W., Tsai, S-T., Wei, H. P. & Jin, Y. T., 2011 Jul 1, In : Journal of Clinical Pathology. 64, 7, p. 571-577 7 p.

Research output: Contribution to journalArticle

Papillomaviridae
Taiwan
Oncogenic Viruses
In Situ Hybridization
Carcinogenesis
2010
31 Citations (Scopus)

Hypothyroidism After Radiotherapy for Nasopharyngeal Cancer Patients

Wu, Y. H., Wang, H. M., Chen, H. H. W., Lin, C. Y., Chen, E. Y. C., Fan, K. H., Huang, S. F., Chen, I. H., Liao, C. T., Cheng, A. J. & Chang, J. T. C., 2010 Mar 15, In : International Journal of Radiation Oncology Biology Physics. 76, 4, p. 1133-1139 7 p.

Research output: Contribution to journalArticle

Nasopharyngeal Neoplasms
Hypothyroidism
radiation therapy
Radiotherapy
cancer
92 Citations (Scopus)

Increase of programmed death-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma

Hsu, M. C., Hsiao, J. R., Chang, K. C., Wu, Y. H., Su, I. J., Jin, Y. T. & Chang, Y., 2010 Oct 1, In : Modern Pathology. 23, 10, p. 1393-1403 11 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Recurrence
Neoplasms
Ligands
Tumor Microenvironment
2006
25 Citations (Scopus)
acceleration (physics)
radiation therapy
Radiotherapy
cancer
Neck