• 338 Citations
  • 12 h-Index
20062019
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Research Output 2006 2019

  • 338 Citations
  • 12 h-Index
  • 27 Article
2019

Protein Glycation by Glyoxal Promotes Amyloid Formation by Islet Amyloid Polypeptide

Hsu, Y. H., Chen, Y-W., Wu, M. H. & Tu, L. H., 2019 Jun 18, In : Biophysical Journal. 116, 12, p. 2304-2313 10 p.

Research output: Contribution to journalArticle

Glyoxal
Islet Amyloid Polypeptide
Amyloid
Type 2 Diabetes Mellitus
Peptide Hormones
2018
KATP Channels
Palmitic Acid
Insulin
Glucose
Glyburide

Functional engineered mesenchymal stem cells with fibronectin-gold composite coated catheters for vascular tissue regeneration

Chen, Y., Hsieh, S., Yang, Y., Hsu, S., Kung, M., Lin, P., Hsieh, H., Lin, C., Tang, C. & Hung, H., 2018 Apr 1, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 3, p. 699-711

Research output: Contribution to journalArticle

2 Citations (Scopus)
Amino Acid Transport System X-AG
High Fat Diet
Neuroglia
Lactic Acid
Hippocampus
3 Citations (Scopus)

High-fat diet suppresses the astrocytic process arborization and downregulates the glial glutamate transporters in the hippocampus of mice

Tsai, S. F., Wu, H. T., Chen, P., Chen, Y-W., Yu, M., Wang, T. F., Wu, S. Y., Tzeng, S-F. & Kuo, Y-M., 2018 Dec 1, In : Brain Research. 1700, p. 66-77 12 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
High Fat Diet
Neuronal Plasticity
Neuroglia
Hippocampus

High-fat diet suppresses the astrocytic process arborization and downregulates the glial glutamate transporters in the hippocampus of mice.

Tsai, SF., Wu, HT., Chen, PC. & Chen, Y-W., 2018 Jul 13, In : Brain Research. 18, p. 30401 3 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
High Fat Diet
Neuronal Plasticity
Neuroglia
Hippocampus
2017
3 Citations (Scopus)

Selective serotonin reuptake inhibitor, fluoxetine, impairs E-cadherin-mediated cell adhesion and alters calcium homeostasis in pancreatic beta cells

Chang, H. Y., Chen, S. L., Shen, M. R., Kung, M. L., Chuang, L. M. & Chen, Y. W., 2017 Dec 1, In : Scientific reports. 7, 1, 3515.

Research output: Contribution to journalArticle

Fluoxetine
Serotonin Uptake Inhibitors
Insulin-Secreting Cells
Cadherins
Cell Adhesion

Silver decorated copper oxide (Ag@CuO) nanocomposite enhances ROS-mediated bacterial architecture collapse

Kung, M., Tai, M., Lin, P., Wu, D., Wu, W., Yeh, B., Hung, H., Kuo, C., Chen, Y., Hsieh, S. & Hsieh, S., 2017 Jul 1, In : Colloids and Surfaces B: Biointerfaces. 155, p. 399-407

Research output: Contribution to journalArticle

4 Citations (Scopus)

STIM1-dependent Ca2+ signaling regulates podosome formation to facilitate cancer cell invasion

Chen, Y-W., Chen, Y. F., Chiu, W. T., Chen, H. C. & Shen, M. R., 2017 Dec 1, In : Scientific reports. 7, 1, 11523.

Research output: Contribution to journalArticle

Neoplasms
Cell Surface Extensions
Rosette Formation
Podosomes
Extracellular Matrix
2016
13 Citations (Scopus)

Estrogen ameliorates microglial activation by inhibiting the Kir2.1 inward-rectifier K+ channel

Wu, S. Y., Chen, Y-W., Tsai, S. F., Wu, S-N., Shih, Y. H., Jiang-Shieh, Y. F., Yang, T. T. & Kuo, Y-M., 2016 Mar 10, In : Scientific reports. 6, 22864.

Research output: Contribution to journalArticle

Inwardly Rectifying Potassium Channel
Estradiol
Dopaminergic Neurons
Estrogens
Parkinson Disease

Magnetite nanoparticle interactions with insulin amyloid fibrils

Chen, Y., Chang, C., Hung, H., Kung, M., Yeh, B. & Hsieh, S., 2016 Oct 14, In : Nanotechnology. 27, 41, p. 415702

Research output: Contribution to journalArticle

Prominent Vascularization Capacity of Mesenchymal Stem Cells in Collagen–Gold Nanocomposites

Hsieh, S., Chen, H., Hsu, S., Yang, Y., Tang, C., Chu, M., Lin, P., Fu, R., Kung, M., Chen, Y., Yeh, B. & Hung, H., 2016 Oct 26, In : ACS applied materials & interfaces. 8, 42, p. 28982-29000

Research output: Contribution to journalArticle

22 Citations (Scopus)

The STIM1-Orai1 pathway of store-operated Ca2+ entry controls the checkpoint in cell cycle G1/S transition

Chen, Y. W., Chen, Y. F., Chen, Y. T., Chiu, W. T. & Shen, M. R., 2016 Feb 26, In : Scientific reports. 26, 6, 22142.

Research output: Contribution to journalArticle

G1 Phase Cell Cycle Checkpoints
Cell Cycle
Down-Regulation
Cell Membrane Structures
Phosphorylation
2015
10 Citations (Scopus)

Aging and exercise affect hippocampal neurogenesis via different mechanisms

Yang, T. T., Lo, C. P., Tsai, P. S., Wu, S. Y., Wang, T. F., Chen, Y-W., Jiang-Shieh, Y. F. & Kuo, Y-M., 2015 Jul 6, In : PloS one. 10, 7, e0132152.

Research output: Contribution to journalArticle

neurogenesis
Neurogenesis
Neurons
stem cells
Stem cells
4 Citations (Scopus)

Glucose regulates amyloid β production via AMPK

Yang, T. T., Shih, Y. S., Chen, Y-W., Kuo, Y-M. & Lee, C. W., 2015 Oct 1, In : Journal of Neural Transmission. 122, 10, p. 1381-1390 10 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Amyloid
Glucose
Alzheimer Disease
Cultured Cells
2013
17 Citations (Scopus)

Enhancing cytokine-induced killer cell therapy of multiple myeloma

Liu, C., Suksanpaisan, L., Chen, Y-W., Russell, S. J. & Peng, K. W., 2013 Jun 1, In : Experimental Hematology. 41, 6, p. 508-517 10 p.

Research output: Contribution to journalArticle

Cytokine-Induced Killer Cells
Cell- and Tissue-Based Therapy
Multiple Myeloma
Measles virus
Cytokines
2012
24 Citations (Scopus)

Catalase prevents maternal diabetes-induced perinatal programming via the Nrf2-HO-1 defense system

Chang, S. Y., Chen, Y-W., Zhao, X. P., Chenier, I., Tran, S., Sauvé, A., Ingelfinger, J. R. & Zhang, S. L., 2012 Oct 1, In : Diabetes. 61, 10, p. 2565-2574 10 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Catalase
Mothers
Kidney
Green Fluorescent Proteins
2011
34 Citations (Scopus)

Angiotensin II type II receptor deficiency accelerates the development of nephropathy in type i diabetes via oxidative stress and ACE2

Chang, S. Y., Chen, Y-W., Chenier, I., Tran, S. L. M. & Zhang, S. L., 2011 Dec 1, In : Experimental Diabetes Research. 2011, 521076.

Research output: Contribution to journalArticle

Angiotensins
Type 1 Diabetes Mellitus
Knockout Mice
Angiotensin II
Oxidative Stress
16 Citations (Scopus)

High glucose promotes nascent nephron apoptosis via NF-κB and p53 pathways

Chen, Y-W., Chenier, I., Chang, S. Y., Tran, S., Ingelfinger, J. R. & Zhang, S. L., 2011 Jan 1, In : American Journal of Physiology - Renal Physiology. 300, 1

Research output: Contribution to journalArticle

Nephrons
Apoptosis
Glucose
Kidney
Reactive Oxygen Species
2010
39 Citations (Scopus)

Maternal diabetes programs hypertension and kidney injury in offspring

Chen, Y-W., Chenier, I., Tran, S., Scotcher, M., Chang, S. Y. & Zhang, S. L., 2010 Jul 1, In : Pediatric Nephrology. 25, 7, p. 1319-1329 11 p.

Research output: Contribution to journalArticle

Glucose Intolerance
Mothers
Hypertension
Kidney
Gene Expression
2008
10 Citations (Scopus)

Deficiency of intrarenal angiotensin II type 2 receptor impairs paired homeo box-2 and N-myc expression during nephrogenesis

Chen, Y-W., Tran, S., Chenier, I., Chan, J. S. D., Ingelfinger, J. R., Inagami, T. & Zhang, S. L., 2008 Jul 9, In : Pediatric Nephrology. 23, 10, p. 1769-1777 9 p.

Research output: Contribution to journalArticle

Angiotensin Type 2 Receptor
Homeobox Genes
Kidney
Knockout Mice
Angiotensin II
64 Citations (Scopus)

Maternal diabetes modulates renal morphogenesis in offspring

Tran, S., Chen, Y-W., Chenier, I., Chan, J. S. D., Quaggin, S., Hébert, M. J., Ingelfinger, J. R. & Zhang, S. L., 2008 May 1, In : Journal of the American Society of Nephrology. 19, 5, p. 943-952 10 p.

Research output: Contribution to journalArticle

Morphogenesis
Mothers
Kidney
Podocytes
Angiotensinogen
2007
12 Citations (Scopus)

Pax-2 and N-myc regulate epithelial cell proliferation and apoptosis in a positive autocrine feedback loop

Zhang, S. L., Chen, Y-W., Tran, S., Liu, F., Nestoridi, E., Hébert, M. J. & Ingelfinger, J. R., 2007 Jun 1, In : Pediatric Nephrology. 22, 6, p. 813-824 12 p.

Research output: Contribution to journalArticle

Homeobox Genes
Epithelial Cells
Cell Proliferation
Apoptosis
Reactive Oxygen Species
23 Citations (Scopus)

Reactive oxygen species in the presence of high glucose alter ureteric bud morphogenesis

Zhang, S. L., Chen, Y-W., Tran, S., Chenier, I., Hébert, M. J. & Ingelfinger, J. R., 2007 Jan 1, In : Journal of the American Society of Nephrology. 18, 7, p. 2105-2115 11 p.

Research output: Contribution to journalArticle

Morphogenesis
Reactive Oxygen Species
Glucose
Homeobox Genes
Kidney
2006
20 Citations (Scopus)

Heterogeneous nuclear ribonucleoprotein K modulates angiotensinogen gene expression in kidney cells

Wei, C. C., Zhang, S. L., Chen, Y-W., Guo, D. F., Ingelfinger, J. R., Bomsztyk, K. & Chan, J. S. D., 2006 Sep 1, In : Journal of Biological Chemistry. 281, 35, p. 25344-25355 12 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein K
Angiotensinogen
Gene expression
Kidney
Gene Expression
18 Citations (Scopus)

Reactive oxygen species and nuclear factor-kappa B pathway mediate high glucose-induced Pax-2 gene expression in mouse embryonic mesenchymal epithelial cells and kidney explants

Chen, Y-W., Liu, F., Tran, S., Zhu, Y., Hébert, M. J., Ingelfinger, J. R. & Zhang, S. L., 2006 Nov 1, In : Kidney International. 70, 9, p. 1607-1615 9 p.

Research output: Contribution to journalArticle

NF-kappa B
Reactive Oxygen Species
Epithelial Cells
Kidney
Gene Expression