α-Nitro carbonyl compounds in the synthesis of 2,3-dihydrofurans

Che Ping Chuang; Kuang Po Chen; Yu Lin Hsu; An I. Tsai; Shui Te Liu

doi:10.1016/j.tet.2008.05.122

α-Nitro carbonyl compounds in the synthesis of 2,3-dihydrofurans

Che Ping Chuang, Kuang Po Chen, Yu Lin Hsu, An I. Tsai, Shui Te Liu

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

A new method for the synthesis of 2,3-dihydrofurans from readily available starting enones and α-nitro carbonyl compounds has been developed. This protocol can provide a novel and effective methodology for the preparation of 2,3-dihydrofurans in a stereoselective fashion. With 1,4-dien-3-ones, 2,3-dihydrofurans and cyclohexenecarboxylates were produced and high chemoselectivity was observed in different solvents.

Original language	English
Pages (from-to)	7511-7516
Number of pages	6
Journal	Tetrahedron
Volume	64
Issue number	32
DOIs	https://doi.org/10.1016/j.tet.2008.05.122
Publication status	Published - 2008 Aug 4

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tet.2008.05.122

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title = "α-Nitro carbonyl compounds in the synthesis of 2,3-dihydrofurans",

abstract = "A new method for the synthesis of 2,3-dihydrofurans from readily available starting enones and α-nitro carbonyl compounds has been developed. This protocol can provide a novel and effective methodology for the preparation of 2,3-dihydrofurans in a stereoselective fashion. With 1,4-dien-3-ones, 2,3-dihydrofurans and cyclohexenecarboxylates were produced and high chemoselectivity was observed in different solvents.",

author = "Chuang, {Che Ping} and Chen, {Kuang Po} and Hsu, {Yu Lin} and Tsai, {An I.} and Liu, {Shui Te}",

note = "Funding Information: We are grateful to the National Science Council of ROC for financial support (Grant No. NSC-95-2113-M-006-010-MY3).",

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AU - Chuang, Che Ping

AU - Chen, Kuang Po

AU - Hsu, Yu Lin

AU - Tsai, An I.

AU - Liu, Shui Te

N1 - Funding Information: We are grateful to the National Science Council of ROC for financial support (Grant No. NSC-95-2113-M-006-010-MY3).

PY - 2008/8/4

Y1 - 2008/8/4

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AB - A new method for the synthesis of 2,3-dihydrofurans from readily available starting enones and α-nitro carbonyl compounds has been developed. This protocol can provide a novel and effective methodology for the preparation of 2,3-dihydrofurans in a stereoselective fashion. With 1,4-dien-3-ones, 2,3-dihydrofurans and cyclohexenecarboxylates were produced and high chemoselectivity was observed in different solvents.

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α-Nitro carbonyl compounds in the synthesis of 2,3-dihydrofurans

Abstract

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