某大學新生的父母親社經地位與代謝異常之相關性研究

The aim of this study was to investigate the association of parental past and current socioeconomic status (SES) with metabolic abnormalities (MA) in young adults. A total of 4,552 subjects from an entrance health checkup survey in a University in 2007 was recruited in our study. Each subject completed a self-administrated structured questionnaire and received the measurements of anthropometric indexes, blood pressure, fasting plasma sugar, and lipid profile. The parental past and current SES were classified according to the modified Hollingshead's index of social position (ISP), calculated by the sum of education level times 4 and occupation level times 7. The MA were defined if more than 2 of the below 5 criteria were met: waist circumference ≧90 cm in men and ≧80 cm in women; TG ≧150 mg/dL; HDL-c ＜40 mg/dL in men and＜50 mg/dL in women; fasting plasma glucose ≧100 mg/dL; systolic blood pressure ≧130 mmHg or diastolic blood pressure ≧85 mmHg. The prevalence of MA was 11.8%. When compared to the subjects without MA, there were older and more male, higher proportion of smoking and drinking habits, family history of diabetes and hypertension, and higher levels of systolic and diastolic blood pressure, fasting plasma glucose, TG, total cholesterol, but lower levels of HDL-c, physical activity, parental education, household income, parent occupation and ISP in the subjects with MA. The subjects with low parental past and current ISP had significantly higher proportion of central obesity, blood pressure, and blood sugar, but lower level of HDL-c than high parental ISP subjects. After adjusting for other variables, the household income, parental current and past ISP were independently associated with MA. in conclusion, the parental current and past ISP were an associated factor of MA in young adult, therefore, we must consider not only current parental SES but also past parental SES when exploring the association between SES and MA.