2018 expert consensus on the management of adverse effects of antiplatelet therapy for acute coronary syndrome in Taiwan

Yi Heng Li, Chih Yuan Fang, I. Chang Hsieh, Wei Chun Huang, Tsung Hsien Lin, Shih Hsien Sung, Chiung Zuan Chiu, Chiung Jen Wu, Kou Gi Shyu, Po Yuan Chang, Ching Chang Fang, Tse Min Lu, Ching Pei Chen, Wei Chen Tai, Chau Chyun Sheu, Kai Che Wei, Yi Hsiu Huang, Hsing Mei Wu, Juey Jen Hwang

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Abstract

Antiplatelet therapy is a key component in the treatment of acute coronary syndrome (ACS). The management of ACS has evolved considerably over recent years with the development of new and more potent antiplatelet agents. Clinical trials on ACS have demonstrated that potent antiplatelet agents can more effectively reduce cardiovascular events. However, there is a tipping point between safety and efficacy, beyond which the risk of bleeding and other adverse effects can outweigh the benefits of antiplatelet therapy. Striking a balance between safety and efficacy remains a major challenge. A consensus meeting of an expert panel composed of Taiwanese experts was held to provide recommendations for the management of adverse effects in patients with ACS receiving antiplatelet therapy. The common adverse effects of antiplatelet therapy include upper gastrointestinal bleeding, ecchymosis, hematuria, epistaxis and ticagrelor-related dyspnea. In this study, a literature review of these adverse events was performed and recommendations for the management were made.

Original languageEnglish
Pages (from-to)201-210
Number of pages10
JournalActa Cardiologica Sinica
Volume34
Issue number3
DOIs
Publication statusPublished - 2018 May

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All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Li, Y. H., Fang, C. Y., Hsieh, I. C., Huang, W. C., Lin, T. H., Sung, S. H., Chiu, C. Z., Wu, C. J., Shyu, K. G., Chang, P. Y., Fang, C. C., Lu, T. M., Chen, C. P., Tai, W. C., Sheu, C. C., Wei, K. C., Huang, Y. H., Wu, H. M., & Hwang, J. J. (2018). 2018 expert consensus on the management of adverse effects of antiplatelet therapy for acute coronary syndrome in Taiwan. Acta Cardiologica Sinica, 34(3), 201-210. https://doi.org/10.6515/ACS.201805_34(3).20180302A