@inproceedings{74dc8cf7dbc74226aeee087d464a72d5,
title = "22.7 A Programmable Wireless EEG Monitoring SoC with Open/Closed-Loop Optogenetic and Electrical Stimulation for Epilepsy Control",
abstract = "The number of studies on closed-loop detection and electrical stimulation systems [1]-[2] for efficient control of neurological disorders is increasing, because recent clinical studies have shown their efficiency and usefulness in symptom suppression. Electrical stimulation can produce enough stimulation to affect a large range of nerves. However, all nerves near the stimulus are excited and hurt, and over time, currents start to exceed acceptable limits. Therefore, optogenetic stimulation [3]-[4] has become compelling in recent years due to several advantages: (1) no artificial noise on the EEG; (2) ability to stimulate specific nerves; and (3) no injurious effects on nerves. In this study, a wireless programmable stimulating system-on-chip (WPSSoC) is reported that provides wireless open/closed-loop optogenetic and electrical stimulation to improve treatment for epilepsy suppression. The system is demonstrated on programmable stimulation parameters wirelessly controlled by a software Graphical User Interface (GUI) on a computer. Moreover, an animal experiment conducted on optogenetic tissue was successful, thereby demonstrating that the nerve injury on optogenetic stimulation is lower than that of electrical stimulation.",
author = "Lee, {Shuenn Yuh} and Chieh Tsou and Huang, {Peng Wei} and Cheng, {Po Hao} and Liao, {Chi Chung} and Liao, {Zhan Xien} and Lee, {Hao Yun} and Lin, {Chou Ching} and Hsieh, {Chia Hsiang}",
year = "2019",
month = mar,
day = "6",
doi = "10.1109/ISSCC.2019.8662385",
language = "English",
series = "Digest of Technical Papers - IEEE International Solid-State Circuits Conference",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "372--374",
booktitle = "2019 IEEE International Solid-State Circuits Conference, ISSCC 2019",
address = "United States",
note = "2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 ; Conference date: 17-02-2019 Through 21-02-2019",
}