3-T proton magnetic resonance spectroscopy of central neurocytoma: 3 Case reports and review of the literature

Ming-Tsung Chuang, Wei Chen Lin, Huei Yi Tsai, Gin Chung Liu, Shih Wen Hu, I. Chan Chiang

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Central neurocytoma (CNC), first described by Hassoun et al in 1982, is a rare neuronal tumor of the central nervous system, accounting for 0.25% to 0.5% of all central nervous system tumors. To our knowledge, there are only 5 published articles reporting the magnetic resonance spectroscopy (MRS) findings of neurocytomas. The 3-T proton MRS findings of 3 cases with CNC confirmed by immunohistochemical stains are reported here. Increased choline (Cho)/creatine (Cr) ratios with decreased N-acetylaspartate (NAA)/Cr ratios were observed in all 3 cases, but only 1 case had an increased peak at 3.55 ppm known as glycine (Gly). The other case with an increased alanine peak at 1.5 ppm had a poor prognosis. Therefore, we conclude that the presence of a Gly peak may suggest the diagnosis of CNC but that the absence of Gly does not exclude the diagnosis of CNC.

Original languageEnglish
Pages (from-to)683-688
Number of pages6
JournalJournal of computer assisted tomography
Volume29
Issue number5
DOIs
Publication statusPublished - 2005 Sep 1

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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