@article{343f2c3a60444420b61df29b209ea23e,
title = "3D localization of clustered microcalcifications using cranio-caudal and medio-lateral oblique views",
abstract = "This paper presents a 3D localization method to register clustered microcalcifications on mammograms from cranio-caudal (CC) and medio-lateral oblique (MLO) views. The method consists of three major components: registration of clustered microcalcifications in CC and MLO views, 3D localization of clustered microcalcifications and 3D visualization of clustered microcalcifications. The registration is performed based on three features, gradient, energy and local entropy codes that are independent of spatial locations of microcalcifications in two different views and are prioritized by discriminability in a binary decision tree. The 3D localization is determined by a sequence of coordinate corrections of calcified pixels using the breast nipple as a controlling point. Finally, the 3D visualization implements a virtual reality modeling language viewer (VRMLV) to view the exact location of the lesion as a guide for needle biopsy. In order to validate our proposed 3D localization system, a set of breast lesions, which appear both in mammograms and in MR Images is used for experiments where the depth of clustered microcalcifications can be verified by the MR images.",
author = "Yang, {Sheng Chih} and Hsu, {Hsian He} and Hsu, {Giu Cheng} and Chung, {Pau Choo} and Guo, {Shu Mei} and Lo, {Chien Shen} and Yang, {Ching Wen} and Lee, {San Kan} and Chang, {Chein I.}",
note = "Funding Information: The work was supported by National Science Council and Taichung Veterans General Hospital, Taiwan under the grant NSC90-2213-E-006-092, TCVGH-895501C, respectively. Funding Information: Chein-I Chang received his BS degree from Soochow University, Taipei, Taiwan, 1973, MS degree from the Institute of Mathematics at National Tsing Hua University, Hsinchu, Taiwan, 1975 and MA degree from the State University of New York at Stony Brook, in 1977, all in mathematics. He also received his MS, MSEE degrees from the University of Illinois at Urbana-Champaign, in 1982 and PhD degree in electrical engineering from the University of Maryland, College Park, in 1987. Dr Chang has been with the University of Maryland Baltimore County (UMBC) since 1987, as a visiting assistant professor from January 1987 to August 1987, Assistant Professor from 1987 to 1993, associate professor from 1993 to 2001 and professor in the Department of Computer Science and Electrical Engineering since 2001. He was a visiting research specialist in the Institute of Information Engineering at the National Cheng Kung University, Taiwan, from 1994 to 1995. He received an NRC (National Research Council) senior research associate ship award from 2002 to 2003 sponsored by the US Army Soldier and Biological Chemical Command, Edgewood Chemical and Biological Center, Aberdeen Proving Ground, Maryland. He has three patents and several patents pending. He is on the editorial board of the Journal of High Speed Networks and was the guest editor of a special issue of the same journal on telemedicine and applications. His research interests include multispectral/hyperspectral image processing, automatic target recognition, medical imaging, information theory and coding, signal detection and estimation and neural networks. He has authored a book, Hyperspectral Imaging: Techniques for Spectral Detection and Classification published by Kluwer Academic Publishers. Dr Chang is an Associate Editor in the area of hyperspectral signal processing for IEEE Transaction on Geoscience and Remote Sensing and a Fellow of SPIE and a member of Phi Kappa Phi and Eta Kappa Nu.",
year = "2005",
month = oct,
doi = "10.1016/j.compmedimag.2005.05.001",
language = "English",
volume = "29",
pages = "521--532",
journal = "Computerized Medical Imaging and Graphics",
issn = "0895-6111",
publisher = "Elsevier Limited",
number = "7",
}