TY - GEN
T1 - 3D photo-crosslinking pattern scaffold for cell application by two-photon laser scanning system
AU - Wang, Yu Fu
AU - Liang, Jen I.
AU - Lee, Chien Te
AU - Yeh, Ming Long
AU - Chen, Shean Jen
PY - 2011/10/4
Y1 - 2011/10/4
N2 - In this study, we fabricated a photo-crosslinking, biocompatible 3D Poly(ethylene) glycol (PEG) hydrogel scaffold with inner fibrin gel for cell adhesion. We tested the material cytocompatibility with 3T3 fibroblasts then processed the cell adhesion motif inside the scaffold at regular and L-shaped 3D structural pattern by two-photon laser scanning system for further cell manipulation and recording. The results show cell could survive under UV irradiation and grew in the inner fibrin gel scaffold. The desired pattern scaffold has potential to apply in cell guided migration and physiological signal recording.
AB - In this study, we fabricated a photo-crosslinking, biocompatible 3D Poly(ethylene) glycol (PEG) hydrogel scaffold with inner fibrin gel for cell adhesion. We tested the material cytocompatibility with 3T3 fibroblasts then processed the cell adhesion motif inside the scaffold at regular and L-shaped 3D structural pattern by two-photon laser scanning system for further cell manipulation and recording. The results show cell could survive under UV irradiation and grew in the inner fibrin gel scaffold. The desired pattern scaffold has potential to apply in cell guided migration and physiological signal recording.
UR - http://www.scopus.com/inward/record.url?scp=80053310436&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80053310436&partnerID=8YFLogxK
U2 - 10.1109/NEMS.2011.6017400
DO - 10.1109/NEMS.2011.6017400
M3 - Conference contribution
AN - SCOPUS:80053310436
SN - 9781612847757
T3 - NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
SP - 491
EP - 494
BT - NEMS 2011 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems
T2 - 6th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2011
Y2 - 20 February 2011 through 23 February 2011
ER -