6-Pentadecylsalicylic acid; An antithrombin component isolated from the stem of Rhus semialata var. roxburghii

S. C. Kuo; C. M. Teng; L. G. Lee; T. H. Chiu; T. S. Wu; S. C. Huang; J. B. Wu; T. Y. Shieh; R. J. Chang; T. C. Chou

doi:10.1055/s-2006-960083

6-Pentadecylsalicylic acid; An antithrombin component isolated from the stem of Rhus semialata var. roxburghii

S. C. Kuo, C. M. Teng, L. G. Lee, T. H. Chiu, T. S. Wu, S. C. Huang, J. B. Wu, T. Y. Shieh, R. J. Chang, T. C. Chou

School of Pharmacy

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

Bioassay-directed fractionation of the n-hexane extract of the stem of Rhus semialata Murr. var. roxburghii DC (Anacardiaceae) has led to the isolation of 6-pentadecylsalicylic acid. It showed antithrombin activity at 50 μg/ml in the amidolytic method. It also prolonged the clotting time in a dose-dependent manner in the clotting assay of thrombin-fibrinogen interaction.

Original language	English
Pages (from-to)	247-249
Number of pages	3
Journal	Planta Medica
Volume	57
Issue number	3
DOIs	https://doi.org/10.1055/s-2006-960083
Publication status	Published - 1991

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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title = "6-Pentadecylsalicylic acid; An antithrombin component isolated from the stem of Rhus semialata var. roxburghii",

abstract = "Bioassay-directed fractionation of the n-hexane extract of the stem of Rhus semialata Murr. var. roxburghii DC (Anacardiaceae) has led to the isolation of 6-pentadecylsalicylic acid. It showed antithrombin activity at 50 μg/ml in the amidolytic method. It also prolonged the clotting time in a dose-dependent manner in the clotting assay of thrombin-fibrinogen interaction.",

author = "Kuo, {S. C.} and Teng, {C. M.} and Lee, {L. G.} and Chiu, {T. H.} and Wu, {T. S.} and Huang, {S. C.} and Wu, {J. B.} and Shieh, {T. Y.} and Chang, {R. J.} and Chou, {T. C.}",

year = "1991",

doi = "10.1055/s-2006-960083",

language = "English",

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T1 - 6-Pentadecylsalicylic acid; An antithrombin component isolated from the stem of Rhus semialata var. roxburghii

AU - Kuo, S. C.

AU - Teng, C. M.

AU - Lee, L. G.

AU - Chiu, T. H.

AU - Wu, T. S.

AU - Huang, S. C.

AU - Wu, J. B.

AU - Shieh, T. Y.

AU - Chang, R. J.

AU - Chou, T. C.

PY - 1991

Y1 - 1991

N2 - Bioassay-directed fractionation of the n-hexane extract of the stem of Rhus semialata Murr. var. roxburghii DC (Anacardiaceae) has led to the isolation of 6-pentadecylsalicylic acid. It showed antithrombin activity at 50 μg/ml in the amidolytic method. It also prolonged the clotting time in a dose-dependent manner in the clotting assay of thrombin-fibrinogen interaction.

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JF - Planta Medica

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ER -

6-Pentadecylsalicylic acid; An antithrombin component isolated from the stem of Rhus semialata var. roxburghii

Abstract

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