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2018

Design and conduct of clinical trials for breast cancer

Klimberg, V. S., Shyr, Y. & Wells, T., 2018 Jan 1, The Breast: Comprehensive Management of Benign and Malignant Diseases. Elsevier Inc., p. 362-376.e1

Research output: Chapter in Book/Report/Conference proceedingChapter

Controlled Clinical Trials
Clinical Trials
Breast Neoplasms
National Institutes of Health (U.S.)
Laboratory Animals
2016
2 Citations (Scopus)

Disrupted cooperation between transcription factors across diverse cancer types

Wang, J., Liu, Q., Sun, J. & Shyr, Y., 2016 Aug 5, In : BMC genomics. 17, 1, 560.

Research output: Contribution to journalArticle

Open Access
Transcription Factors
Neoplasms
Interferon Regulatory Factors
Survival
Proxy
15 Citations (Scopus)

Utility of [ 18 F]FSPG PET to Image Hepatocellular Carcinoma: First Clinical Evaluation in a US Population

Kavanaugh, G., Williams, J., Morris, A. S., Nickels, M. L., Walker, R., Koglin, N., Stephens, A. W., Washington, M. K., Geevarghese, S. K., Liu, Q., Ayers, D., Shyr, Y. & Manning, H. C., 2016 Dec 1, In : Molecular Imaging and Biology. 18, 6, p. 924-934 11 p.

Research output: Contribution to journalArticle

Positron-Emission Tomography
Hepatocellular Carcinoma
Population
Acetates
Neoplasms
3 Citations (Scopus)

Heterozygosity ratio, a robust global genomic measure of autozygosity and its association with height and disease risk

Samuels, D. C., Wang, J., Ye, F., He, J., Levinson, R. T., Sheng, Q., Zhao, S., Capra, J. A., Shyr, Y., Zheng, W. & Guo, Y., 2016 Nov, In : Genetics. 204, 3, p. 893-904 12 p.

Research output: Contribution to journalArticle

Open Access
Population Genetics
Population
Phenotype
Datasets
2017
7 Citations (Scopus)

Integrated molecular analysis reveals complex interactions between genomic and epigenomic alterations in esophageal adenocarcinomas

Peng, D., Guo, Y., Chen, H., Zhao, S., Washington, K., Hu, T., Shyr, Y. & El-Rifai, W., 2017 Jan 19, In : Scientific reports. 7, 40729.

Research output: Contribution to journalArticle

Open Access
Epigenomics
Adenocarcinoma
Gene Expression
Methylation
Genes
6 Citations (Scopus)

The discrepancy among single nucleotide variants detected by DNA and RNA high throughput sequencing data

Guo, Y., Zhao, S., Sheng, Q., Samuels, D. C. & Shyr, Y., 2017 Oct 3, In : BMC genomics. 18, 690.

Research output: Contribution to journalArticle

Open Access
High-Throughput Nucleotide Sequencing
Nucleotides
RNA Sequence Analysis
DNA
DNA Sequence Analysis
7 Citations (Scopus)

Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia

Chen, Z., Soutto, M., Rahman, B., Fazili, M. W., Peng, D. F., Blanca Piazuelo, M., Chen, H., Kay Washington, M., Shyr, Y. & El-Rifai, W., 2017 Jul, In : Genes Chromosomes and Cancer. 56, 7, p. 535-547 13 p.

Research output: Contribution to journalArticle

Stomach
Stomach Neoplasms
Neoplasms
Catenins
Knockout Mice
2016
10 Citations (Scopus)

Mitochondria sequence mapping strategies and practicability of mitochondria variant detection from exome and RNA sequencing data

Zhang, P., Samuels, D. C., Lehmann, B., Stricker, T., Pietenpol, J., Shyr, Y. & Guo, Y., 2016 Mar 1, In : Briefings in bioinformatics. 17, 2, p. 224-232 9 p.

Research output: Contribution to journalArticle

Open Access
Exome
RNA Sequence Analysis
Mitochondria
Nucleotides
Polymorphism
2017

Implementing a standard-of-care clinic for stroke prevention in children with sickle cell disease in Nigeria: A feasible strategy outside a clinical trial setting

Galadanci, N. A., Abdullahi, S. U., Vance, L. D., Tabari, M. A., Abubakar, S., Belonwu, R., Salihu, A., Galadanci, A. A., Jibir, B. W., Gambo, S., Suwaid, S., Bello-Manga, H., Neville, K., Kirkham, F., Shyr, Y., Phillips, S., Covert, B. V., Kassim, A. A., Trevathan, E., Jordan, L. C. & 2 others, Aliyu, M. H. & DeBaun, M. R., 2017 Dec 8, In : Blood Advances. 1, p. 23-25 3 p.

Research output: Contribution to journalShort survey

Open Access
2019

Extramedullary leukemia behaving as solid cancer: clinical, histologic, and genetic clues to chemoresistance in organ sites

Cunningham, I., Hamele-Bena, D., Guo, Y., Shiomi, T., Papp, A. C., Chakravarti, B., Yang, J., Shyr, Y. & Fisher, R. A., 2019 Nov 1, In : American Journal of Hematology. 94, 11, p. 1200-1207 8 p.

Research output: Contribution to journalArticle

Leukemia
Neoplasms
Bone Marrow
Breast Neoplasms
Treatment Failure
2017
5 Citations (Scopus)

Non-Invasive Glutamine PET Reflects Pharmacological Inhibition of BRAFV600E In Vivo

Schulte, M. L., Hight, M. R., Ayers, G. D., Liu, Q., Shyr, Y., Washington, M. K. & Manning, H. C., 2017 Jun 1, In : Molecular Imaging and Biology. 19, 3, p. 421-428 8 p.

Research output: Contribution to journalArticle

Glutamine
Positron-Emission Tomography
Colonic Neoplasms
Pharmacology
Colorectal Neoplasms
2016
224 Citations (Scopus)

Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection

Lehmann, B. D., Jovanović, B., Chen, X., Estrada, M. V., Johnson, K. N., Shyr, Y., Moses, H. L., Sanders, M. E. & Pietenpol, J. A., 2016 Jan 1, In : PloS one. 11, 6, p. e0157368

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
Chemotherapy
breast neoplasms
drug therapy
Drug Therapy
2018
3 Citations (Scopus)

Dynamics of Zebrafish Heart Regeneration Using an HPLC-ESI-MS/MS Approach

Ma, D., Tu, C., Sheng, Q., Yang, Y., Kan, Z., Guo, Y., Shyr, Y., Scott, I. C. & Lou, X., 2018 Mar 2, In : Journal of Proteome Research. 17, 3, p. 1300-1308 9 p.

Research output: Contribution to journalArticle

Zebrafish
Regeneration
High Pressure Liquid Chromatography
Proteins
Functional analysis
2017
2 Citations (Scopus)

Functional data classification using covariate-adjusted subspace projection

Li, P. L., Chiou, J. M. & Shyr, Y., 2017 Nov 1, In : Computational Statistics and Data Analysis. 115, p. 21-34 14 p.

Research output: Contribution to journalArticle

Functional Data
Data Classification
Covariates
Subspace
Projection
2016
87 Citations (Scopus)

Evidence Combination from an Evolutionary Game Theory Perspective

Deng, X., Han, D., Dezert, J., Deng, Y. & Shyr, Y., 2016 Sep, In : IEEE Transactions on Cybernetics. 46, 9, p. 2070-2082 13 p., 7194765.

Research output: Contribution to journalArticle

Information fusion
Game theory
2018
3 Citations (Scopus)

Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

Wang, J., Zhao, Y., Zhou, X., Hiebert, S. W., Liu, Q. & Shyr, Y., 2018 Aug 23, In : BMC genomics. 19, 1, 633.

Research output: Contribution to journalArticle

Open Access
RNA Sequence Analysis
Genes
Technology
DNA-Directed RNA Polymerases
Knockout Mice
2017
10 Citations (Scopus)

IGFBP3 modulates lung tumorigenesis and cell growth through IGF1 signaling

Wang, Y. A., Sun, Y., Palmer, J., Solomides, C., Huang, L. C., Shyr, Y., Dicker, A. P. & Lu, B., 2017 Jul, In : Molecular Cancer Research. 15, 7, p. 896-904 9 p.

Research output: Contribution to journalArticle

Open Access
Insulin-Like Growth Factor Binding Protein 3
Carcinogenesis
Lung
Growth
Lung Neoplasms
2 Citations (Scopus)

Shanghai score: A prognostic and adjuvant treatment-evaluating system constructed for Chinese patients with hepatocellular carcinoma after curative resection

Sun, H. C., Xie, L., Yang, X. R., Li, W., Yu, J., Zhu, X. D., Xia, Y., Zhang, T., Xu, Y., Hu, B., Du, L. P., Zeng, L. Y., Ouyang, J., Zhang, W., Song, T. Q., Li, Q., Shi, Y. H., Zhou, J., Qiu, S. J., Liu, Q. & 5 others, Li, Y. X., Tang, Z. Y., Shyr, Y., Shen, F. & Fan, J., 2017 Nov 20, In : Chinese Medical Journal. 130, 22, p. 2650-2660 11 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Therapeutics
Survival
Fetal Proteins
Cancer Care Facilities
24 Citations (Scopus)

The Utilization of Formalin Fixed-Paraffin-Embedded Specimens in High Throughput Genomic Studies

Zhang, P., Lehmann, B. D., Shyr, Y. & Guo, Y., 2017 Jan 1, In : International Journal of Genomics. 2017, 1926304.

Research output: Contribution to journalReview article

Open Access
Paraffin
Formaldehyde
Throughput
Assays
Tissue
22 Citations (Scopus)

Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance

Giltnane, J. M., Hutchinson, K. E., Stricker, T. P., Formisano, L., Young, C. D., Estrada, M. V., Nixon, M. J., Du, L., Sanchez, V., Ericsson, P. G., Kuba, M. G., Sanders, M. E., Mu, X. J., Van Allen, E. M., Wagle, N., Mayer, I. A., Abramson, V., Gómez, H., Rizzo, M., Toy, W. & 15 others, Chandarlapaty, S., Mayer, E. L., Christiansen, J., Murphy, D., Fitzgerald, K., Wang, K., Ross, J. S., Miller, V. A., Stephens, P. J., Yelensky, R., Garraway, L., Shyr, Y., Meszoely, I., Balko, J. M. & Arteaga, C. L., 2017 Aug 9, In : Science Translational Medicine. 9, 402, aai7993.

Research output: Contribution to journalArticle

Open Access
letrozole
Estrogens
Breast Neoplasms
Estrogen Receptor Modulators
Neoplasms
2018
3 Citations (Scopus)

LNK deficiency promotes acute aortic dissection and rupture

Laroumanie, F., Korneva, A., Bersi, M. R., Alexander, M. R., Xiao, L., Zhong, X., Van Beusecum, J. P., Chen, Y., Saleh, M. A., McMaster, W. G., Gavulic, K. A., Dale, B. L., Zhao, S., Guo, Y., Shyr, Y., Perrien, D. S., Cox, N. J., Curci, J. A., Humphrey, J. D. & Madhur, M. S., 2018 Oct 18, In : JCI Insight. 3, 20

Research output: Contribution to journalArticle

Open Access
Aortic Rupture
Dissection
Angiotensin II
Neutrophils
Adoptive Transfer
2017
14 Citations (Scopus)

Feasibility trial for primary stroke prevention in children with sickle cell anemia in Nigeria (SPIN trial)

Galadanci, N. A., Umar Abdullahi, S., Vance, L. D., Musa Tabari, A., Ali, S., Belonwu, R., Salihu, A., Amal Galadanci, A., Wudil Jibir, B., Bello-Manga, H., Neville, K., Kirkham, F. J., Shyr, Y., Phillips, S., Covert, B. V., Kassim, A. A., Jordan, L. C., Aliyu, M. H. & DeBaun, M. R., 2017 Aug, In : American Journal of Hematology. 92, 8, p. 780-788 9 p.

Research output: Contribution to journalArticle

Open Access
Sickle Cell Anemia
Primary Prevention
Nigeria
Hydroxyurea
Stroke
2018
54 Citations (Scopus)

The impact of smoking and tp53 mutations in lung adenocarcinoma patients with targetable mutations—the lung cancer mutation consortium (LCMC2)

Aisner, D. L., Sholl, L. M., Berry, L. D., Rossi, M. R., Chen, H., Fujimoto, J., Moreira, A. L., Ramalingam, S. S., Villaruz, L. C., Otterson, G. A., Haura, E., Politi, K., Glisson, B., Cetnar, J., Garon, E. B., Schiller, J., Waqar, S. N., Sequist, L. V., Brahmer, J., Shyr, Y. & 7 others, Kugler, K., Wistuba, I. I., Johnson, B. E., Minna, J. D., Kris, M. G., Bunn, P. A. & Kwiatkowski, D. J., 2018 Mar 1, In : Clinical Cancer Research. 24, 5, p. 1038-1047 10 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Smoking
Mutation
High-Throughput Nucleotide Sequencing
Survival
2016

Practicability of mitochondrial heteroplasmy detection through an Illumina genotyping array

Zhang, P., Samuels, D. C., Zhao, S., Wang, J., Shyr, Y. & Guo, Y., 2016 Nov 1, In : Mitochondrion. 31, p. 75-78 4 p.

Research output: Contribution to journalArticle

Fluorescence
Exome
Molecular Epidemiology
Validation Studies
Mitochondrial DNA
2017

Sample size calculation for differential expression analysis of RNA-seq data

Hoskins, S. P., Shyr, D. & Shyr, Y., 2017 Oct 3, Frontiers of Biostatistical Methods and Applications in Clinical Oncology. Springer Singapore, p. 359-379 21 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Sample Size Calculation
Precision Medicine
Differential Expression
Sample Size
Research Design
2016
3 Citations (Scopus)

Mitochondria single nucleotide variation across six blood cell types

Zhang, P., Samuels, D. C., Wang, J., Zhao, S., Shyr, Y. & Guo, Y., 2016 May 1, In : Mitochondrion. 28, p. 16-22 7 p.

Research output: Contribution to journalArticle

Blood Cells
Mitochondria
Nucleotides
Mitochondrial DNA
Single Nucleotide Polymorphism
3 Citations (Scopus)

A novel resistance mutation in eccC5 of the ESX-5 secretion system confers ofloxacin resistance in Mycobacterium tuberculosis

Eilertson, B., Maruri, F., Blackman, A., Guo, Y., Herrera, M., van der Heijden, Y., Shyr, Y. & Sterling, T. R., 2016 Sep 1, In : The Journal of antimicrobial chemotherapy. 71, 9, p. 2419-2427 9 p.

Research output: Contribution to journalArticle

Open Access
Ofloxacin
Mycobacterium tuberculosis
Mutation
DNA Gyrase
Fluoroquinolones
2018

First-line Chemotherapy Responsiveness and Patterns of Metastatic Spread Identify Clinical Syndromes Present Within Advanced KRAS Mutant Non–Small-cell Lung Cancer With Different Prognostic Significance

Iams, W. T., Yu, H., Shyr, Y., Patil, T., Horn, L., McCoach, C., Kelly, K., Doebele, R. C. & Camidge, D. R., 2018 Nov, In : Clinical Lung Cancer. 19, 6, p. 531-543 13 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Drug Therapy
Survival
Confidence Intervals
Disease-Free Survival

Proteome analysis implicates adaptive changes in metabolism and body wall musculature of Caenorhabditis elegans Dauer Larva

Zaidi, A. K., Vukoti, K., Sheng, Q., Shyr, Y. & Miyagi, M., 2018 Jun, In : Journal of Integrated OMICS. 8, 1, p. 46-53 8 p., 237.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Proteome
Metabolism
Larva
Proteins
2017

Corrigendum to "Comparative Study of Exome Copy Number Variation Estimation Tools Using Array Comparative Genomic Hybridization as Control"

Guo, Y., Sheng, Q., Samuels, D. C., Lehmann, B., Bauer, J. A., Pietenpol, J. & Shyr, Y., 2017 Jan 1, In : BioMed research international. 2017, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Exome
Comparative Genomic Hybridization
corrigendum
2016
1 Citation (Scopus)
Sample Size Calculation
Differential Expression
Generalized Linear Model
RNA
Sample Size
14 Citations (Scopus)

Practicability of detecting somatic point mutation from RNA high throughput sequencing data

Sheng, Q., Zhao, S., Li, C. I., Shyr, Y. & Guo, Y., 2016 May 1, In : Genomics. 107, 5, p. 163-169 7 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Point Mutation
Mutation
DNA Sequence Analysis
Research Personnel
2018
3 Citations (Scopus)

RnaSeqSampleSize: Real data based sample size estimation for RNA sequencing

Zhao, S., Li, C. I., Guo, Y., Sheng, Q. & Shyr, Y., 2018 May 30, In : BMC Bioinformatics. 19, 1, 191.

Research output: Contribution to journalArticle

RNA Sequence Analysis
RNA
Sample Size
Sequencing
Genes
2016
63 Citations (Scopus)

Clinical and Biological Insights Into Combined Post- and Pre-Capillary Pulmonary Hypertension

Assad, T. R., Hemnes, A. R., Larkin, E. K., Glazer, A. M., Xu, M., Wells, Q. S., Farber-Eger, E. H., Sheng, Q., Shyr, Y., Harrell, F. E., Newman, J. H. & Brittain, E. L., 2016 Dec 13, In : Journal of the American College of Cardiology. 68, 23, p. 2525-2536 12 p.

Research output: Contribution to journalArticle

Open Access
Pulmonary Hypertension
Heart Diseases
Vascular Diseases
Lung Diseases
Single Nucleotide Polymorphism
18 Citations (Scopus)

Connecting the Dots: Therapy-Induced Senescence and a Tumor-Suppressive Immune Microenvironment

Vilgelm, A. E., Johnson, C. A., Prasad, N., Yang, J., Chen, S. C., Ayers, G. D., Pawlikowski, J. S., Raman, D., Sosman, J. A., Kelley, M., Ecsedy, J. A., Shyr, Y., Levy, S. E. & Richmond, A., 2016 Jun 1, In : Journal of the National Cancer Institute. 108, 6, djv406.

Research output: Contribution to journalArticle

Open Access
Neoplasms
Leukocytes
Therapeutics
Melanoma
Immunotherapy
2017
6 Citations (Scopus)

Power and sample size calculations for high-throughput sequencing-based experiments

Li, C-I., Samuels, D. C., Zhao, Y. Y., Shyr, Y. & Guo, Y., 2017 May 30, In : Briefings in bioinformatics. 19, 6, p. 1247-1255 9 p.

Research output: Contribution to journalArticle

Sample Size
Throughput
Microarrays
Experiments
RNA Sequence Analysis
4 Citations (Scopus)

Estimating relative mitochondrial DNA copy number using high throughput sequencing data

Zhang, P., Lehmann, B. D., Samuels, D. C., Zhao, S., Zhao, Y. Y., Shyr, Y. & Guo, Y., 2017 Oct, In : Genomics. 109, 5-6, p. 457-462 6 p.

Research output: Contribution to journalArticle

Open Access
Mitochondrial DNA
Mitochondria
Polymerase Chain Reaction
Genome
Exome
5 Citations (Scopus)

A comparative analysis between sequential boost and integrated boost intensity-modulated radiation therapy with concurrent chemotherapy for locally-advanced head and neck cancer

Vlacich, G., Stavas, M. J., Pendyala, P., Chen, S. C., Shyr, Y. & Cmelak, A. J., 2017 Jan 13, In : Radiation Oncology. 12, 1, 13.

Research output: Contribution to journalArticle

Open Access
Head and Neck Neoplasms
Radiotherapy
Drug Therapy
Gastrostomy
Survival

StrandScript: Evaluation of Illumina genotyping array design and strand correction

Wang, J., Samuels, D. C., Shyr, Y. & Guo, Y., 2017 Aug 1, In : Bioinformatics. 33, 15, p. 2399-2401 3 p.

Research output: Contribution to journalArticle

Open Access
Single Nucleotide Polymorphism
Evaluation
Throughput
Meta-Analysis
Processing
2018

Erratum to: Feasibility trial for primary stroke prevention in children with sickle cell anemia in Nigeria (SPIN trial) (American Journal of Hematology, (2017), 92, 8, (780-788), 10.1002/ajh.24770)

Galadanci, N. A., Umar Abdullahi, S., Vance, L. D., Musa Tabari, A., Ali, S., Belonwu, R., Salihu, A., Amal Galadanci, A., Wudil Jibir, B., Bello-Manga, H., Neville, K., Kirkham, F. J., Shyr, Y., Phillips, S., Covert, B. V., Kassim, A. A., Jordan, L. C., Aliyu, M. H. & DeBaun, M. R., 2018 Mar, In : American Journal of Hematology. 93, 3, p. E83

Research output: Contribution to journalComment/debate

Open Access
Medication Adherence
Sickle Cell Anemia
Hematology
Primary Prevention
Nigeria
2019
7 Citations (Scopus)

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

Formisano, L., Lu, Y., Servetto, A., Hanker, A. B., Jansen, V. M., Bauer, J. A., Sudhan, D. R., Guerrero-Zotano, A. L., Croessmann, S., Guo, Y., Ericsson, P. G., Lee, K. M., Nixon, M. J., Schwarz, L. J., Sanders, M. E., Dugger, T. C., Cruz, M. R., Behdad, A., Cristofanilli, M., Bardia, A. & 11 others, O’Shaughnessy, J., Nagy, R. J., Lanman, R. B., Solovieff, N., He, W., Miller, M., Su, F., Shyr, Y., Mayer, I. A., Balko, J. M. & Arteaga, C. L., 2019 Dec 1, In : Nature communications. 10, 1, 1373.

Research output: Contribution to journalArticle

Open Access
breast
inhibitors
cancer
Breast Neoplasms
Protein-Tyrosine Kinases
2018
3 Citations (Scopus)

Treatment options in idiopathic subglottic stenosis: Protocol for a prospective international multicentre pragmatic trial

Gelbard, A., Shyr, Y., Berry, L., Hillel, A. T., Ekbom, D. C., Edell, E. S., Kasperbauer, J. L., Lott, D. G., Donovan, D. T., Garrett, C. G., Sandhu, G., Daniero, J. J., Netterville, J. L., Schindler, J. S., Smith, M. E., Bryson, P. C., Lorenz, R. R. & Francis, D. O., 2018 Apr 1, In : BMJ open. 8, 4, e022243.

Research output: Contribution to journalArticle

Pragmatic Clinical Trials
Multicenter Studies
Pathologic Constriction
Deglutition
Therapeutics
2016
6 Citations (Scopus)

Performance Investigation of Proteomic Identification by HCD/CID Fragmentations in Combination with High/Low-Resolution Detectors on a Tribrid, High-Field Orbitrap Instrument

Tu, C., Li, J., Shen, S., Sheng, Q., Shyr, Y. & Qu, J., 2016 Jan 1, In : PloS one. 11, 7, p. e0160160

Research output: Contribution to journalArticle

Open Access
Proteomics
proteomics
detectors
Ions
Detectors
2017
33 Citations (Scopus)

Etoposide and cisplatin versus paclitaxel and carboplatin with concurrent thoracic radiotherapy in unresectable stage III non-small cell lung cancer: A multicenter randomized phase III trial

Liang, J., Bi, N., Wu, S., Chen, M., Lv, C., Zhao, L., Shi, A., Jiang, W., Xu, Y., Zhou, Z., Wang, W., Chen, D., Hui, Z., Lv, J., Zhang, H., Feng, Q., Xiao, Z., Wang, X., Liu, L., Zhang, T. & 7 others, Du, L., Chen, W., Shyr, Y., Yin, W., Li, J., He, J. & Wang, L., 2017 Apr 1, In : Annals of Oncology. 28, 4, p. 777-783 7 p., mdx009.

Research output: Contribution to journalArticle

Open Access
Carboplatin
Etoposide
Non-Small Cell Lung Carcinoma
Paclitaxel
Cisplatin
16 Citations (Scopus)

Institute of Medicine Measures of Social and Behavioral Determinants of Health: A Feasibility Study

Giuse, N. B., Koonce, T. Y., Kusnoor, S. V., Prather, A. A., Gottlieb, L. M., Huang, L. C., Phillips, S. E., Shyr, Y., Adler, N. E. & Stead, W. W., 2017 Feb 1, In : American Journal of Preventive Medicine. 52, 2, p. 199-206 8 p.

Research output: Contribution to journalArticle

Social Determinants of Health
National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division
Feasibility Studies
Random Allocation
Health
2019
4 Citations (Scopus)

Systems Biology Analyses Show Hyperactivation of Transforming Growth Factor-β and JNK Signaling Pathways in Esophageal Cancer

Blum, A. E., Venkitachalam, S., Ravillah, D., Chelluboyina, A. K., Kieber-Emmons, A. M., Ravi, L., Kresak, A., Chandar, A. K., Markowitz, S. D., Canto, M. I., Wang, J. S., Shaheen, N. J., Guo, Y., Shyr, Y., Willis, J. E., Chak, A., Varadan, V. & Guda, K., 2019 May, In : Gastroenterology. 156, 6, p. 1761-1774 14 p.

Research output: Contribution to journalArticle

Systems Biology
Transforming Growth Factors
Esophageal Neoplasms
Adenocarcinoma
Phosphotransferases
3 Citations (Scopus)

beRBP: binding estimation for human RNA-binding proteins

Yu, H., Wang, J., Sheng, Q., Liu, Q. & Shyr, Y., 2019 Mar 18, In : Nucleic acids research. 47, 5, p. e26

Research output: Contribution to journalArticle

Open Access
RNA-Binding Proteins
RNA
Benchmarking
Protein Binding
1 Citation (Scopus)

HACER: An atlas of human active enhancers to interpret regulatory variants

Wang, J., Dai, X., Berry, L. D., Cogan, J. D., Liu, Q. & Shyr, Y., 2019 Jan 8, In : Nucleic acids research. 47, D1, p. D106-D112

Research output: Contribution to journalArticle

Open Access
Atlases
Transcription Factors
Gene Regulatory Networks
Nucleic Acid Regulatory Sequences
Genome-Wide Association Study
2016
29 Citations (Scopus)

A Distinct Lung-Interstitium-Resident Memory CD8 + T Cell Subset Confers Enhanced Protection to Lower Respiratory Tract Infection

Gilchuk, P., Hill, T. M., Guy, C., McMaster, S. R., Boyd, K. L., Rabacal, W. A., Lu, P., Shyr, Y., Kohlmeier, J. E., Sebzda, E., Green, D. R. & Joyce, S., 2016 Aug 16, In : Cell Reports. 16, 7, p. 1800-1809 10 p.

Research output: Contribution to journalArticle

Open Access
T-cells
T-Lymphocyte Subsets
Respiratory Tract Infections
Vaccination
Data storage equipment
3 Citations (Scopus)

Effects of combination PPARγ agonist and angiotensin receptor blocker on glomerulosclerosis

Matsushita, K., Yang, H. C., Mysore, M. M., Zhong, J., Shyr, Y., Ma, L. J. & Fogo, A. B., 2016 Jun 1, In : Laboratory Investigation. 96, 6, p. 602-609 8 p.

Research output: Contribution to journalArticle

pioglitazone
Peroxisome Proliferator-Activated Receptors
Angiotensin Receptor Antagonists
Blood Pressure
Podocytes