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2011
A locked nucleic acid clamp-mediated PCR assay for detection of a p53 codon 249 hotspot mutation in urine
Lin, S. Y., Dhillon, V., Jain, S., Chang, T. T., Hu, C. T., Lin, Y. J., Chen, S. H., Chang, K. C., Song, W., Yu, L., Block, T. M. & Su, Y. H., 2011 Sep, In: Journal of Molecular Diagnostics. 13, 5, p. 474-484 11 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
Association of intrahepatic cccDNA reduction with the improvement of liver histology in chronic hepatitis B patients receiving oral antiviral agents
Cheng, P. N., Liu, W. C., Tsai, H. W., Wu, I. C., Chang, T. T. & Young, K. C., 2011 Apr 1, In: Journal of Medical Virology. 83, 4, p. 602-607 6 p.Research output: Contribution to journal › Article › peer-review
41 Citations (Scopus) -
Discovering clinical biomarkers of chronic hepatitis B by mining mutation hotspots
Cheng, C. P., Lee, P. F., Chin, C. Y., Liu, W. C., Wu, I. C., Chang, T. T. & Tseng, V. S., 2011 Dec 1, Proceedings - 2011 Conference on Technologies and Applications of Artificial Intelligence, TAAI 2011. p. 51-56 6 p. 6120719. (Proceedings - 2011 Conference on Technologies and Applications of Artificial Intelligence, TAAI 2011).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
3 Citations (Scopus) -
Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein
Lee, J. W., Liao, P. C., Young, K. C., Chang, C. L., Chen, S. S. L., Chang, T. T., Lai, M. D. & Wang, S. W., 2011 Oct 7, In: Journal of Proteome Research. 10, 10, p. 4522-4534 13 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
Methylation of the CpG sites only on the sense strand of the APC gene is specific for hepatocellular carcinoma
Jain, S., Chang, T. T., Hamilton, J. P., Lin, S. Y., Lin, Y. J., Evans, A. A., Selaru, F. M., Lin, P. W., Chen, S. H., Block, T. M., Hu, C. T., Song, W., Meltzer, S. J. & Su, Y. H., 2011 Nov 2, In: PloS one. 6, 11, e26799.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
Novel nucleotide and amino acid covariation between the 5′UTR and the NS2/NS3 proteins of hepatitis C virus: Bioinformatic and functional analyses
Sun, H. Y., Ou, N. Y., Wang, S. W., Liu, W. C., Cheng, T. F., Shr, S. J., Sun, K. T., Chang, T. T. & Young, K. C., 2011 Sep 28, In: PloS one. 6, 9, e25530.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Tenofovir disoproxil fumarate (TDF), emtricitabine/TDF, and entecavir in patients with decompensated chronic hepatitis B liver disease
Liaw, Y. F., Sheen, I. S., Lee, C. M., Akarca, U. S., Papatheodoridis, G. V., Suet-Hing Wong, F., Chang, T. T., Horban, A., Wang, C., Kwan, P., Buti, M., Prieto, M., Berg, T., Kitrinos, K., Peschell, K., Mondou, E., Frederick, D., Rousseau, F. & Schiff, E. R., 2011 Jan, In: Hepatology. 53, 1, p. 62-72 11 p.Research output: Contribution to journal › Article › peer-review
256 Citations (Scopus) -
2012
Analysis of precore/core covariances associated with viral kinetics and genotypes in hepatitis B e antigen-positive chronic hepatitis B patients
Cheng, C. P., Lee, P. F., Liu, W. C., Wu, I. C., Chin, C. Y., Chang, T. T. & Tseng, V. S., 2012 Feb 27, In: PloS one. 7, 2, e32553.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Efficacy of telbivudine in Taiwanese chronic hepatitis B patients compared with GLOBE extension study and predicting treatment outcome by HBV DNA kinetics at Week 24
Hsu, C. W., Chao, Y. C., Lee, C. M., Chang, T. T. & Chen, Y. C., 2012 Dec 13, In: BMC Gastroenterology. 12, 178.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma
Yen, C. J., Lin, Y. J., Yen, C. S., Tsai, H. W., Tsai, T. F., Chang, K. Y., Huang, W. C., Lin, P. W., Chiang, C. W. & Chang, T. T., 2012 Jul 27, In: PloS one. 7, 7, e41931.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
High Rates of Viral Suppression After Long-term Entecavir Treatment of Asian Patients With Hepatitis B e Antigen-Positive Chronic Hepatitis B
Pan, C. Q., Tong, M., Kowdley, K. V., Hu, K. Q., Chang, T. T., Lai, C. L., Yoon, S. K., Lee, S. S., Cohen, D., Tang, H. & Tsai, N., 2012 Sep, In: Clinical Gastroenterology and Hepatology. 10, 9, p. 1047-1050.e1Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Impact of increasing alanine aminotransferase levels within normal range on incident diabetes
Wang, C. S., Chang, T. T., Yao, W. J., Wang, S. T. & Chou, P., 2012 Apr, In: Journal of the Formosan Medical Association. 111, 4, p. 201-208 8 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma
Jain, S., Chen, S., Chang, K. C., Lin, Y. J., Hu, C. T., Boldbaatar, B., Hamilton, J. P., Lin, S. Y., Chang, T. T., Chen, S. H., Song, W., Meltzer, S. J., Block, T. M. & Su, Y. H., 2012 Apr 20, In: PloS one. 7, 4, e35789.Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus) -
Long-term safety and tolerability of entecavir in patients with chronic hepatitis B in the rollover study ETV-901
Manns, M. P., Akarca, U. S., Chang, T. T., Sievert, W., Yoon, S. K., Tsai, N., Min, A., Pangerl, A., Beebe, S., Yu, M. & Wongcharatrawee, S., 2012 May, In: Expert Opinion on Drug Safety. 11, 3, p. 361-368 8 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
2014
All-oral daclatasvir plus asunaprevir for hepatitis C virus genotype 1b: A multinational, phase 3, multicohort study
Manns, M., Pol, S., Jacobson, I. M., Marcellin, P., Gordon, S. C., Peng, C. Y., Chang, T. T., Everson, G. T., Heo, J., Gerken, G., Yoffe, B., Towner, W. J., Bourliere, M., Metivier, S., Chu, C. J., Sievert, W., Bronowicki, J. P., Thabut, D., Lee, Y. J., Kao, J. H. & 6 others, , 2014, In: The Lancet. 384, 9954, p. 1597-1605 9 p.Research output: Contribution to journal › Article › peer-review
283 Citations (Scopus) -
Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production
Lin, C. C., Tsai, P., Sun, H. Y., Hsu, M. C., Lee, J. C., Wu, I. C., Tsao, C. W., Chang, T. T. & Young, K. C., 2014, In: Journal of Hepatology. 61, 5, p. 984-993 10 p.Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus) -
Association of serum IgG N-glycome and transforming growth factor-β1 with hepatitis B virus e antigen seroconversion during entecavir therapy
Ho, C. H., Chien, R. N., Cheng, P. N., Liu, C. K., Su, C. S., Wu, I. C., Liu, W. C., Chen, S. H. & Chang, T. T., 2014 Nov, In: Antiviral Research. 111, p. 121-128 8 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Effects of tenofovir disoproxil fumarate in hepatitis B e antigen-positive patients with normal levels of alanine aminotransferase and high levels of hepatitis B virus DNA
Chan, H. L. Y., Chan, C. K., Hui, A. J., Chan, S., Poordad, F., Chang, T. T., Mathurin, P., Flaherty, J. F., Lin, L., Corsa, A., Gaggar, A., Subramanian, G. M., McHutchison, J. G., Lee, S. & Gane, E. J., 2014 May, In: Gastroenterology. 146, 5, p. 1240-1248 9 p.Research output: Contribution to journal › Article › peer-review
89 Citations (Scopus) -
Efficacy of entecavir in chronic hepatitis B patients with persistently normal alanine aminotransferase: Randomized, double-blind, placebo-controlled study
Tseng, K. C., Chen, C. Y., Tsai, H. W., Chang, T. T., Chuang, W. L., Hsu, P. I., Liu, W. C. & Cheng, P. N., 2014, In: Antiviral Therapy. 19, 8, p. 755-764 10 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
HBsAg expression of liver correlates with histological activities and viral replication in chronic hepatitis B
Cheng, P. N., Chiu, Y. C., Tsai, H. W., Wang, R. H., Chiu, H. C., Wu, I. C. & Chang, T. T., 2014 Nov 1, In: Annals of Hepatology. 13, 6, p. 771-780 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Peginterferon alfa-2a is associated with elevations in alanine aminotransferase at the end of treatment in chronic hepatitis C patients with sustained virologic response
Tseng, C. W., Chen, C. Y., Chang, T. T., Tzeng, S. J., Hsieh, Y. H., Hung, T. H., Lee, C. C., Wu, S. F. & Tseng, K. C., 2014 Jun 17, In: PloS one. 9, 6, e100207.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
2016
Aligning to the sample-specific reference sequence to optimize the accuracy of next-generation sequencing analysis for hepatitis B virus
Liu, W. C., Lin, C. P., Cheng, C. P., Ho, C. H., Lan, K. L., Cheng, J. H., Yen, C. J., Cheng, P. N., Wu, I. C., Li, I. C., Chang, B. C. H., Tseng, V. S., Chiu, Y. C. & Chang, T. T., 2016 Jan 1, In: Hepatology International. 10, 1, p. 147-157 11 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
All-oral daclatasvir plus asunaprevir for chronic hepatitis C virus (HCV) genotype 1b infection: a sub-analysis in Asian patients from the HALLMARK DUAL study
Kao, J. H., Lee, Y. J., Heo, J., Ahn, S. H., Lim, Y. S., Peng, C. Y., Chang, T. T., Torbeyns, A., Hughes, E., Bhore, R. & Noviello, S., 2016 Oct 1, In: Liver International. 36, 10, p. 1433-1441 9 p.Research output: Contribution to journal › Article › peer-review
20 Citations (Scopus) -
A phase 3b study of sofosbuvir plus ribavirin in Taiwanese patients with chronic genotype 2 hepatitis C virus infection
Kao, J. H., Chien, R. N., Chang, T. T., Peng, C. Y., Hu, T. H., Lo, G. H., Wang, H. Y., Chen, J. J., Yang, J. C., Knox, S. J., Han, L., Mo, H., Mathias, A., Brainard, D. M., Sheen, I. S., Hsu, Y. C., Chu, C. J. & Chuang, W. L., 2016 Aug 1, In: Liver International. 36, 8, p. 1101-1107 7 p.Research output: Contribution to journal › Article › peer-review
20 Citations (Scopus) -
Aspartate aminotransferase to platelet ratio index and sustained virologic response are associated with progression from hepatitis c associated liver cirrhosis to hepatocellular carcinoma after treatment with pegylated interferon plus ribavirin
Ng, K. J., Tseng, C. W., Chang, T. T., Tzeng, S. J., Hsieh, Y. H., Hung, T. H., Huang, H. T., Wu, S. F. & Tseng, K. C., 2016 Aug 1, In: Clinical Interventions in Aging. 11, p. 1035-1041 7 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Association of sustained virologic response with reduced progression to liver cirrhosis in elderly patients with chronic hepatitis C
Tseng, C. W., Chang, T. T., Tzeng, S. J., Hsieh, Y. H., Hung, T. H., Huang, H. T., Wu, S. F. & Tseng, K. C., 2016 Mar 17, In: Clinical Interventions in Aging. 11, p. 327-334 8 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
DeF-GPU: Efficient and effective deletions finding in hepatitis B viral genomic DNA using a GPU architecture
Cheng, C. P., Lan, K. L., Liu, W. C., Chang, T. T. & Tseng, V. S., 2016 Dec 1, In: Methods. 111, p. 56-63 8 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Ledipasvir/sofosbuvir fixed-dose combination tablet in Taiwanese patients with chronic genotype 1 hepatitis C virus
Chuang, W. L., Chien, R. N., Peng, C. Y., Chang, T. T., Lo, G. H., Sheen, I. S., Wang, H. Y., Chen, J. J., Yang, J. C., Knox, S. J., Gao, B., Garrison, K. L., Mo, H., Pang, P. S., Hsu, Y. C., Hu, T. H., Chu, C. J. & Kao, J. H., 2016 Jul 1, In: Journal of Gastroenterology and Hepatology (Australia). 31, 7, p. 1323-1329 7 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Peginterferon lambda for the treatment of HBeAg-positive chronic hepatitis B: A randomized phase 2b study (LIRA-B)
LIRA-B Study Team, 2016 May 1, In: Journal of Hepatology. 64, 5, p. 1011-1019 9 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase
Ho, C. H., Chuang, H. C., Wu, I. C., Tsai, H. W., Lin, Y. J., Sun, H. Y., Young, K. C., Chiu, Y. C., Cheng, P. N., Liu, W. C., Tan, T. H. & Chang, T. T., 2016, In: Oncotarget. 7, 31, p. 49765-49776 12 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma
Tsai, H. W., Lin, Y. J., Wu, H. C., Chang, T. T., Wu, I. C., Cheng, P. N., Yen, C. J., Chan, S. H., Huang, W. & Su, I. J., 2016 May 10, In: Oncotarget. 7, 19, p. 27724-27734 11 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
2018
Applications of next-generation sequencing analysis for the detection of hepatocellular carcinoma-associated hepatitis B virus mutations
Wu, I. C., Liu, W. C. & Chang, T. T., 2018 Jun 2, In: Journal of biomedical science. 25, 1, 51.Research output: Contribution to journal › Review article › peer-review
8 Citations (Scopus) -
Clinical utility of hepatitis B surface antigen kinetics in treatment-naïve chronic hepatitis B patients during longterm entecavir therapy
Lin, T. C., Chiu, Y. C., Chiu, H. C., Liu, W. C., Cheng, P. N., Chen, C. Y., Chang, T. T. & Wu, I. C., 2018 Feb 14, In: World journal of gastroenterology. 24, 6, p. 725-736 12 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Efficacy of Ledipasvir and Sofosbuvir Treatment of HCV Infection in Patients Coinfected With HBV
Liu, C. J., Chuang, W. L., Sheen, I. S., Wang, H. Y., Chen, C. Y., Tseng, K. C., Chang, T. T., Massetto, B., Yang, J. C., Yun, C., Knox, S. J., Osinusi, A., Camus, G., Jiang, D., Brainard, D. M., McHutchison, J. G., Hu, T. H., Hsu, Y. C., Lo, G. H., Chu, C. J. & 4 others, , 2018 Mar, In: Gastroenterology. 154, 4, p. 989-997 9 p.Research output: Contribution to journal › Article › peer-review
58 Citations (Scopus) -
Fucosyl-agalactosyl IgG1 induces cholangiocarcinoma metastasis and early recurrence by activating tumor-associated macrophage
Chang, T. T., Tsai, H. W. & Ho, C. H., 2018 Nov 21, In: Cancers. 10, 11, 460.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
High SVR12 with 8-week and 12-week glecaprevir/pibrentasvir therapy: An integrated analysis of HCV genotype 1–6 patients without cirrhosis
Puoti, M., Foster, G. R., Wang, S., Mutimer, D., Gane, E., Moreno, C., Chang, T. T., Lee, S. S., Marinho, R., Dufour, J. F., Pol, S., Hezode, C., Gordon, S. C., Strasser, S. I., Thuluvath, P. J., Zhang, Z., Lovell, S., Pilot-Matias, T. & Mensa, F. J., 2018 Aug, In: Journal of Hepatology. 69, 2, p. 293-300 8 p.Research output: Contribution to journal › Article › peer-review
74 Citations (Scopus) -
Progesterone receptor membrane component 1 as a potential prognostic biomarker for hepatocellular carcinoma
Tsai, H. W., Ho, C. L., Cheng, S. W., Lin, Y. J., Chen, C. C., Cheng, P. N., Yen, C. J., Chang, T. T., Chiang, P. M., Chan, S. H., Ho, C. H., Chen, S. H., Wang, Y. W., Chow, N. H. & Lin, J. C., 2018 Mar 14, In: World journal of gastroenterology. 24, 10, p. 1152-1166 15 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Viral dynamics of persistent hepatitis C virus infection in high-sensitive reporter cells resemble patient's viremia
Tsai, P., Lin, C. C., Sun, H. Y., Lee, J. C., Chang, T. T. & Young, K. C., 2018 Aug, In: Journal of Microbiology, Immunology and Infection. 51, 4, p. 446-455 10 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
2019
Combined transarterial embolization/ chemoembolization-based locoregional treatment with sorafenib prolongs the survival in patients with advanced hepatocellular carcinoma and preserved liver function: A propensity score matching study
Chien, S. C., Chen, C. Y., Cheng, P. N., Liu, Y. S., Cheng, H. C., Chuang, C. H., Chang, T. T., Chiu, H. C., Lin, Y. J. & Chiu, Y. C., 2019, In: Liver Cancer. 8, 3, p. 186-202 17 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Contrast-induced acute kidney injury among patients with chronic kidney disease undergoing imaging studies: A meta-analysis
Lee, Y. C., Hsieh, C. C., Chang, T. T. & Li, C. Y., 2019 Jan 1, In: American Journal of Roentgenology. 213, 4, p. 728-735 8 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Fully galactosyl-fucosyl-bisected IgG 1 reduces anti-HBV efficacy and liver histological improvement
Ho, C. H., Chen, S. H., Tsai, H. W., Wu, I. C. & Chang, T. T., 2019 Mar, In: Antiviral Research. 163, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Plasma proteome plus site-specific N-glycoprofiling for hepatobiliary carcinomas
Chang, T. T., Cheng, J. H., Tsai, H. W., Young, K. C., Hsieh, S. Y. & Ho, C. H., 2019 Jul, In: Journal of Pathology: Clinical Research. 5, 3, p. 199-212 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Telbivudine on IgG-associated hypergammaglobulinemia and TGF-β1 hyperactivity in hepatitis B virus-related liver cirrhosis
Ho, C. H., Chang, T. T. & Chien, R. N., 2019 Nov 1, In: PloS one. 14, 11, e0225482.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
An Effective and Efficient Algorithm for Detecting Exact Deletion Breakpoints from Viral Next-Generation Sequencing Data
Cheng, J. H., Liu, W-C., Chang, T. T., Hsieh, S. Y. & Tseng, V. S., 2020 Dec, Proceedings - 2020 International Computer Symposium, ICS 2020. Institute of Electrical and Electronics Engineers Inc., p. 147-152 6 p. 9359089. (Proceedings - 2020 International Computer Symposium, ICS 2020).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Genotyping of immune-related loci associated with delayed HBeAg seroconversion in immune-active chronic hepatitis B patients
Liu, W. C., Wu, I. C., Chiu, Y. C., Tseng, K. C., Chen, C. Y., Chiu, H. C., Cheng, P. N. & Chang, T. T., 2020 Apr, In: Antiviral Research. 176, 104719.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Impact of Immune Checkpoint Inhibitors with or without a Combination of Tyrosine Kinase Inhibitors on Organ-Specific Efficacy and Macrovascular Invasion in Advanced Hepatocellular Carcinoma
Kuo, H. Y., Chiang, N. J., Chuang, C. H., Chen, C. Y., Wu, I. C., Chang, T. T., Tsai, H. M. & Lin, Y. J., 2020 May 1, In: Oncology Research and Treatment. 43, 5, p. 211-220 10 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Plasma proteome atlas for differentiating tumor stage and post-surgical prognosis of hepatocellular carcinoma and cholangiocarcinoma
Chang, T. T. & Ho, C. H., 2020 Aug, In: PloS one. 15, 8 August, e0238251.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus)