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Author

  • Ting-Tsung Chang
2020
Open Access
Open Access

Plasma proteome atlas for differentiating tumor stage and post-surgical prognosis of hepatocellular carcinoma and cholangiocarcinoma

Chang, T. T. & Ho, C. H., 2020 Aug, In : PloS one. 15, 8 August, e0238251.

Research output: Contribution to journalArticle

Open Access

Contrast-induced acute kidney injury among patients with chronic kidney disease undergoing imaging studies: A meta-analysis

Lee, Y. C., Hsieh, C. C., Chang, T. T. & Li, C. Y., 2019 Jan 1, In : American Journal of Roentgenology. 213, 4, p. 728-735 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Plasma proteome plus site-specific N-glycoprofiling for hepatobiliary carcinomas

Chang, T. T., Cheng, J. H., Tsai, H. W., Young, K. C., Hsieh, S. Y. & Ho, C. H., 2019 Jul, In : Journal of Pathology: Clinical Research. 5, 3, p. 199-212 14 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Telbivudine on IgG-associated hypergammaglobulinemia and TGF-β1 hyperactivity in hepatitis B virus-related liver cirrhosis

Ho, C. H., Chang, T. T. & Chien, R. N., 2019 Nov 1, In : PloS one. 14, 11, e0225482.

Research output: Contribution to journalArticle

Open Access
2018
6 Citations (Scopus)
2 Citations (Scopus)

Efficacy of Ledipasvir and Sofosbuvir Treatment of HCV Infection in Patients Coinfected With HBV

Liu, C. J., Chuang, W. L., Sheen, I. S., Wang, H. Y., Chen, C. Y., Tseng, K. C., Chang, T. T., Massetto, B., Yang, J. C., Yun, C., Knox, S. J., Osinusi, A., Camus, G., Jiang, D., Brainard, D. M., McHutchison, J. G., Hu, T. H., Hsu, Y. C., Lo, G. H., Chu, C. J. & 4 others, Chen, J. J., Peng, C. Y., Chien, R. N. & Chen, P. J., 2018 Mar, In : Gastroenterology. 154, 4, p. 989-997 9 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
2 Citations (Scopus)

High SVR12 with 8-week and 12-week glecaprevir/pibrentasvir therapy: An integrated analysis of HCV genotype 1–6 patients without cirrhosis

Puoti, M., Foster, G. R., Wang, S., Mutimer, D., Gane, E., Moreno, C., Chang, T. T., Lee, S. S., Marinho, R., Dufour, J. F., Pol, S., Hezode, C., Gordon, S. C., Strasser, S. I., Thuluvath, P. J., Zhang, Z., Lovell, S., Pilot-Matias, T. & Mensa, F. J., 2018 Aug, In : Journal of Hepatology. 69, 2, p. 293-300 8 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)
4 Citations (Scopus)

Viral dynamics of persistent hepatitis C virus infection in high-sensitive reporter cells resemble patient's viremia

Tsai, P., Lin, C. C., Sun, H. Y., Lee, J. C., Chang, T. T. & Young, K. C., 2018 Aug, In : Journal of Microbiology, Immunology and Infection. 51, 4, p. 446-455 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

Aligning to the sample-specific reference sequence to optimize the accuracy of next-generation sequencing analysis for hepatitis B virus

Liu, W. C., Lin, C. P., Cheng, C. P., Ho, C. H., Lan, K. L., Cheng, J. H., Yen, C. J., Cheng, P. N., Wu, I. C., Li, I. C., Chang, B. C. H., Tseng, V. S., Chiu, Y. C. & Chang, T. T., 2016 Jan 1, In : Hepatology International. 10, 1, p. 147-157 11 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

All-oral daclatasvir plus asunaprevir for chronic hepatitis C virus (HCV) genotype 1b infection: a sub-analysis in Asian patients from the HALLMARK DUAL study

Kao, J. H., Lee, Y. J., Heo, J., Ahn, S. H., Lim, Y. S., Peng, C. Y., Chang, T-T., Torbeyns, A., Hughes, E., Bhore, R. & Noviello, S., 2016 Oct 1, In : Liver International. 36, 10, p. 1433-1441 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

A phase 3b study of sofosbuvir plus ribavirin in Taiwanese patients with chronic genotype 2 hepatitis C virus infection

Kao, J. H., Chien, R. N., Chang, T. T., Peng, C. Y., Hu, T. H., Lo, G. H., Wang, H. Y., Chen, J. J., Yang, J. C., Knox, S. J., Han, L., Mo, H., Mathias, A., Brainard, D. M., Sheen, I. S., Hsu, Y. C., Chu, C. J. & Chuang, W. L., 2016 Aug 1, In : Liver International. 36, 8, p. 1101-1107 7 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Aspartate aminotransferase to platelet ratio index and sustained virologic response are associated with progression from hepatitis c associated liver cirrhosis to hepatocellular carcinoma after treatment with pegylated interferon plus ribavirin

Ng, K. J., Tseng, C. W., Chang, T. T., Tzeng, S. J., Hsieh, Y. H., Hung, T. H., Huang, H. T., Wu, S. F. & Tseng, K. C., 2016 Aug 1, In : Clinical Interventions in Aging. 11, p. 1035-1041 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Association of sustained virologic response with reduced progression to liver cirrhosis in elderly patients with chronic hepatitis C

Tseng, C. W., Chang, T. T., Tzeng, S. J., Hsieh, Y. H., Hung, T. H., Huang, H. T., Wu, S. F. & Tseng, K. C., 2016 Mar 17, In : Clinical Interventions in Aging. 11, p. 327-334 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

DeF-GPU: Efficient and effective deletions finding in hepatitis B viral genomic DNA using a GPU architecture

Cheng, C. P., Lan, K. L., Liu, W. C., Chang, T. T. & Tseng, V. S., 2016 Dec 1, In : Methods. 111, p. 56-63 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Ledipasvir/sofosbuvir fixed-dose combination tablet in Taiwanese patients with chronic genotype 1 hepatitis C virus

Chuang, W. L., Chien, R. N., Peng, C. Y., Chang, T. T., Lo, G. H., Sheen, I. S., Wang, H. Y., Chen, J. J., Yang, J. C., Knox, S. J., Gao, B., Garrison, K. L., Mo, H., Pang, P. S., Hsu, Y. C., Hu, T. H., Chu, C. J. & Kao, J. H., 2016 Jul 1, In : Journal of Gastroenterology and Hepatology (Australia). 31, 7, p. 1323-1329 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Peginterferon lambda for the treatment of HBeAg-positive chronic hepatitis B: A randomized phase 2b study (LIRA-B)

LIRA-B Study Team, 2016 May 1, In : Journal of Hepatology. 64, 5, p. 1011-1019 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase

Ho, C. H., Chuang, H. C., Wu, I. C., Tsai, H. W., Lin, Y. J., Sun, H. Y., Young, K. C., Chiu, Y. C., Cheng, P. N., Liu, W. C., Tan, T. H. & Chang, T. T., 2016, In : Oncotarget. 7, 31, p. 49765-49776 12 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
11 Citations (Scopus)
2014

All-oral daclatasvir plus asunaprevir for hepatitis C virus genotype 1b: A multinational, phase 3, multicohort study

Manns, M., Pol, S., Jacobson, I. M., Marcellin, P., Gordon, S. C., Peng, C. Y., Chang, T. T., Everson, G. T., Heo, J., Gerken, G., Yoffe, B., Towner, W. J., Bourliere, M., Metivier, S., Chu, C. J., Sievert, W., Bronowicki, J. P., Thabut, D., Lee, Y. J., Kao, J. H. & 6 others, McPhee, F., Kopit, J., Mendez, P., Linaberry, M., Hughes, E. & Noviello, S., 2014 Jan 1, In : The Lancet. 384, 9954, p. 1597-1605 9 p.

Research output: Contribution to journalArticle

273 Citations (Scopus)

Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production

Lin, C. C., Tsai, P., Sun, H. Y., Hsu, M. C., Lee, J. C., Wu, I. C., Tsao, C. W., Chang, T. T. & Young, K. C., 2014 Jan 1, In : Journal of Hepatology. 61, 5, p. 984-993 10 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Association of serum IgG N-glycome and transforming growth factor-β1 with hepatitis B virus e antigen seroconversion during entecavir therapy

Ho, C. H., Chien, R. N., Cheng, P. N., Liu, C. K., Su, C. S., Wu, I. C., Liu, W. C., Chen, S. H. & Chang, T. T., 2014 Nov, In : Antiviral Research. 111, p. 121-128 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Effects of tenofovir disoproxil fumarate in hepatitis B e antigen-positive patients with normal levels of alanine aminotransferase and high levels of hepatitis B virus DNA

Chan, H. L. Y., Chan, C. K., Hui, A. J., Chan, S., Poordad, F., Chang, T. T., Mathurin, P., Flaherty, J. F., Lin, L., Corsa, A., Gaggar, A., Subramanian, G. M., McHutchison, J. G., Lee, S. & Gane, E. J., 2014 May, In : Gastroenterology. 146, 5, p. 1240-1248 9 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Efficacy of entecavir in chronic hepatitis B patients with persistently normal alanine aminotransferase: Randomized, double-blind, placebo-controlled study

Tseng, K. C., Chen, C. Y., Tsai, H. W., Chang, T. T., Chuang, W. L., Hsu, P. I., Liu, W. C. & Cheng, P. N., 2014, In : Antiviral Therapy. 19, 8, p. 755-764 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
Open Access
4 Citations (Scopus)

Peginterferon alfa-2a is associated with elevations in alanine aminotransferase at the end of treatment in chronic hepatitis C patients with sustained virologic response

Tseng, C. W., Chen, C. Y., Chang, T. T., Tzeng, S. J., Hsieh, Y. H., Hung, T. H., Lee, C. C., Wu, S. F. & Tseng, K. C., 2014 Jun 17, In : PloS one. 9, 6, e100207.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2013
11 Citations (Scopus)

Effect of human leukocyte antigen class I and II alleles on hepatitis C viral load among chronic hepatitis C patients in Southern Taiwan

Tseng, K. C., Tseng, C. W., Hsieh, Y. H., Chang, C. K., Lai, N. S., Hung, T. H. & Chang, T. T., 2013 Aug 1, In : Human Immunology. 74, 8, p. 978-982 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Improvement in liver histology among Asian patients with chronic hepatitis B after long-term treatment with entecavir

Tong, M. J., Kowdley, K. V., Pan, C., Hu, K. Q., Chang, T. T., Han, K. H., Yoon, S. K., Goodman, Z. D., Beebe, S., Iloeje, U. & Tang, H., 2013 Apr, In : Liver International. 33, 4, p. 650-651 2 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Lin28B is an oncofetal circulating cancer stem cell-like marker associated with recurrence of hepatocellular carcinoma

Cheng, S. W., Tsai, H. W., Lin, Y. J., Cheng, P. N., Chang, Y. C., Yen, C. J., Huang, H. P., Chuang, Y. P., Chang, T. T., Lee, C. T., Chao, A., Chou, C. Y., Chan, S. H., Chow, N. H. & Ho, C. L., 2013 Nov 14, In : PloS one. 8, 11, e80053.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Quantitative hepatitis B surface antigen analysis in hepatitis B e antigen-positive nucleoside-naive patients treated with entecavir

Gish, R. G., Chang, T. T., Lai, C. L., De Man, R. A., Gadano, A., Llamoso, C. & Tang, H., 2013 Nov 28, In : Antiviral Therapy. 18, 5, p. 691-698 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
26 Citations (Scopus)
2012

Analysis of precore/core covariances associated with viral kinetics and genotypes in hepatitis B e antigen-positive chronic hepatitis B patients

Cheng, C. P., Lee, P. F., Liu, W. C., Wu, I. C., Chin, C. Y., Chang, T. T. & Tseng, V. S., 2012 Feb 27, In : PloS one. 7, 2, e32553.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Efficacy of telbivudine in Taiwanese chronic hepatitis B patients compared with GLOBE extension study and predicting treatment outcome by HBV DNA kinetics at Week 24

Hsu, C. W., Chao, Y. C., Lee, C. M., Chang, T. T. & Chen, Y. C., 2012 Dec 13, In : BMC Gastroenterology. 12, 178.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Hepatitis B virus X protein upregulates mTOR signaling through IKKβ to increase cell proliferation and VEGF production in hepatocellular carcinoma

Yen, C. J., Lin, Y. J., Yen, C. S., Tsai, H. W., Tsai, T. F., Chang, K. Y., Huang, W. C., Lin, P. W., Chiang, C. W. & Chang, T. T., 2012 Jul 27, In : PloS one. 7, 7, e41931.

Research output: Contribution to journalArticle

42 Citations (Scopus)

High Rates of Viral Suppression After Long-term Entecavir Treatment of Asian Patients With Hepatitis B e Antigen-Positive Chronic Hepatitis B

Pan, C. Q., Tong, M., Kowdley, K. V., Hu, K. Q., Chang, T. T., Lai, C. L., Yoon, S. K., Lee, S. S., Cohen, D., Tang, H. & Tsai, N., 2012 Sep, In : Clinical Gastroenterology and Hepatology. 10, 9, p. 1047-1050.e1

Research output: Contribution to journalArticle

12 Citations (Scopus)

Impact of increasing alanine aminotransferase levels within normal range on incident diabetes

Wang, C. S., Chang, T. T., Yao, W. J., Wang, S. T. & Chou, P., 2012 Apr 1, In : Journal of the Formosan Medical Association. 111, 4, p. 201-208 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma

Jain, S., Chen, S., Chang, K. C., Lin, Y. J., Hu, C. T., Boldbaatar, B., Hamilton, J. P., Lin, S. Y., Chang, T. T., Chen, S. H., Song, W., Meltzer, S. J., Block, T. M. & Su, Y. H., 2012 Apr 20, In : PloS one. 7, 4, e35789.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Long-term safety and tolerability of entecavir in patients with chronic hepatitis B in the rollover study ETV-901

Manns, M. P., Akarca, U. S., Chang, T. T., Sievert, W., Yoon, S. K., Tsai, N., Min, A., Pangerl, A., Beebe, S., Yu, M. & Wongcharatrawee, S., 2012 May 1, In : Expert Opinion on Drug Safety. 11, 3, p. 361-368 8 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2011

A locked nucleic acid clamp-mediated PCR assay for detection of a p53 codon 249 hotspot mutation in urine

Lin, S. Y., Dhillon, V., Jain, S., Chang, T. T., Hu, C. T., Lin, Y. J., Chen, S. H., Chang, K. C., Song, W., Yu, L., Block, T. M. & Su, Y. H., 2011 Sep, In : Journal of Molecular Diagnostics. 13, 5, p. 474-484 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
39 Citations (Scopus)

Discovering clinical biomarkers of chronic hepatitis B by mining mutation hotspots

Cheng, C. P., Lee, P. F., Chin, C. Y., Liu, W. C., Wu, I. C., Chang, T. T. & Tseng, V. S., 2011 Dec 1, Proceedings - 2011 Conference on Technologies and Applications of Artificial Intelligence, TAAI 2011. p. 51-56 6 p. 6120719. (Proceedings - 2011 Conference on Technologies and Applications of Artificial Intelligence, TAAI 2011).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein

Lee, J. W., Liao, P. C., Young, K. C., Chang, C. L., Chen, S. S. L., Chang, T. T., Lai, M. D. & Wang, S. W., 2011 Oct 7, In : Journal of Proteome Research. 10, 10, p. 4522-4534 13 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)