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• 2020

  Assessment of Serological Early Biomarker Candidates for Lung Adenocarcinoma by using Multiple Reaction Monitoring-Mass Spectrometry

  Wu, H. Y., Pan, Y. Y., Kopylov, A. T., Zgoda, V., Ma, M. C., Wang, C. H., Su, W. C., Lai, W. W., Cheng, P. N. & Liao, P. C., 2020 Jul 1, In: Proteomics - Clinical Applications. 14, 4, 1900095.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Biomarkers
  • Adenocarcinoma of Lung
  • Mass Spectrometry
  • Monitoring

• Calcium Kidney Stones are Associated with Increased Risk of Carotid Atherosclerosis: The Link between Urinary Stone Risks, Carotid Intima-Media Thickness, and Oxidative Stress Markers

  Huang, H. S., Liao, P. C. & Liu, C. J., 2020 Mar, In: Journal of Clinical Medicine. 9, 3, p. 729

  Research output: Contribution to journal › Article › peer-review

• Comparative UHPLC-Q-Orbitrap HRMS-Based Metabolomics Unveils Biochemical Changes of Black Garlic during Aging Process

  Chang, W. C. W., Chen, Y. T., Chen, H. J., Hsieh, C. W. & Liao, P. C., 2020 Nov 25, In: Journal of Agricultural and Food Chemistry. 68, 47, p. 14049-14058 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolomics
  • Metabolites
  • Garlic
  • garlic
  • metabolomics

• Untargeted foodomics strategy using high-resolution mass spectrometry reveals potential indicators for fish freshness

  Chang, W. C. W., Wu, H. Y., Yeh, Y. & Liao, P. C., 2020 Aug 29, In: Analytica Chimica Acta. 1127, p. 98-105 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass spectrometry
  • Fish
  • Fishes
  • Mass Spectrometry
  • mass spectrometry
  1 Citation (Scopus)
• 2019

  AKT-mediated phosphorylation enhances protein stability and transcription activity of ZNF322A to promote lung cancer progression

  Liao, S. Y., Kuo, I. Y., Chen, Y. T., Liao, P. C., Liu, Y. F., Wu, H. Y., Lai, W. W. & Wang, Y. C., 2019 Oct 10, In: Oncogene. 38, 41, p. 6723-6736 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein Stability
  • Lung Neoplasms
  • Phosphorylation
  • Cyclin D1
  • adducin
  6 Citations (Scopus)

• Assessing the Similarity between Random Copolymer Drug Glatiramer Acetate by Using LC-MS Data Coupling with Hypothesis Testing

  Wu, H. Y., Ma, M. C., Pan, Y. Y., Shih, C. L., Zgoda, V., Li, C. S., Lin, L. C. & Liao, P. C., 2019 Nov 19, In: Analytical chemistry. 91, 22, p. 14281-14289 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Liquid chromatography
  • Glatiramer Acetate
  • Mass spectrometry
  • Copolymers
  • Testing

• Development and validation of an analytical procedure for quantitation of surfactants in dishwashing detergents using ultra-performance liquid chromatography-mass spectrometry

  Wu, H. Y., Shih, C. L., Lee, T., Chen, T. Y., Lin, L. C., Lin, K. Y., Chang, H. C., Chuang, I. C., Liou, S. Y. & Liao, P. C., 2019 Mar 1, In: Talanta. 194, p. 778-785 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Liquid chromatography
  • Mass spectrometry
  • Surface-Active Agents
  • Detergents
  • terics
  6 Citations (Scopus)

• Exposure marker discovery of di-2(propylheptyl) phthalate using ultra-performance liquid chromatography-mass spectrometry and a rat model

  Shih, C. L., Hsu, J. Y., Tien, C. P., Chung, Y. N., Zgoda, V. G. & Liao, P. C., 2019 Apr, In: Journal of Food and Drug Analysis. 27, 2, p. 585-594 10 p.

  Research output: Contribution to journal › Article › peer-review

  • bis(2-propylheptyl)phthalate
  • ultra-performance liquid chromatography
  • phthalates
  • Liquid Chromatography
  • Mass Spectrometry

• Profiling and comparison of toxicant metabolites in hair and urine using a mass spectrometry-based metabolomic data processing method

  Shih, C. L., Wu, H. Y., Liao, P. M., Hsu, J. Y., Tsao, C. Y., Zgoda, V. G. & Liao, P. C., 2019 Apr 4, In: Analytica Chimica Acta. 1052, p. 84-95 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Metabolomics
  • Metabolites
  • Mass spectrometry
  • bis(2-propylheptyl)phthalate
  • hair
  1 Citation (Scopus)

• Quantitative Proteomics of Human Blood Exosomes

  Shushkova, N. A., Vavilov, N. E., Novikova, S. E., Farafonova, T. E., Tikhonova, O. V., Liao, P. C. & Zgoda, V. G., 2019 Apr 1, In: Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 13, 2, p. 132-139 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ultracentrifugation
  • Proteomics
  • Exosomes
  • Sucrose
  • Blood
  1 Citation (Scopus)

• Quantitative Targeted Screening of Proteins Associated with Lung Adenocarcinoma by the Method of Selected Reaction Monitoring

  Kopylov, A. T., Tikhonova, O. V., Farafonova, T. E., Novikova, S. E., Shushkova, N. A., Shevchenko, V. E., Liao, P. C., Archakov, A. I. & Zgoda, V. G., 2019 Jan 1, In: Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 13, 1, p. 60-67 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Adenocarcinoma of Lung
  • Screening
  • Lung Neoplasms
  • Epithelial Cells
  • Plasmas

• Using a high-resolution mass spectrometry-based metabolomics strategy for comprehensively screening and identifying biomarkers of phthalate exposure: Method development and application

  Hsu, J. F., Tien, C. P., Shih, C. L., Liao, P. M., Wong, H. I. & Liao, P. C., 2019 Jul, In: Environment International. 128, p. 261-270 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • phthalate
  • biomarker
  • screening
  • mass spectrometry
  • exposure
  1 Citation (Scopus)
• 2017

  Secretomic Analysis of Host-Pathogen Interactions Reveals That Elongation Factor-Tu Is a Potential Adherence Factor of Helicobacter pylori during Pathogenesis

  Chiu, K. H., Wang, L. H., Tsai, T. T., Lei, H. Y. & Liao, P. C., 2017 Jan 6, In: Journal of Proteome Research. 16, 1, p. 264-273 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Elongation Factor Tu
  • Pathogens
  • Host-Pathogen Interactions
  • Helicobacter pylori
  • THP-1 Cells
  6 Citations (Scopus)
• 2016

  Identification of phosphorylated cyclin-dependent kinase 1 associated with colorectal cancer survival using label-free quantitative analyses

  Lin, P. C., Yang, Y. F., Tyan, Y. C., Hsiao, E. S. L., Chu, P. C., Lee, C. T., Lee, J. C., Chen, Y. M. A. & Liao, P. C., 2016 Jul 1, In: PloS one. 11, 7, e0158844.

  Research output: Contribution to journal › Article › peer-review

  • CDC2 Protein Kinase
  • cyclin-dependent kinase
  • Phosphotyrosine
  • colorectal neoplasms
  • Labels
  10 Citations (Scopus)

• Phosphorylation of CPAP by Aurora-A Maintains Spindle Pole Integrity during Mitosis

  Chou, E. J., Hung, L. Y., Tang, C. J. C., Hsu, W. B., Wu, H. Y., Liao, P. C. & Tang, T. K., 2016 Mar 29, In: Cell Reports. 14, 12, p. 2975-2987 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Phosphorylation
  • Spindle Poles
  • Mitosis
  • Poles
  • Centrioles
  11 Citations (Scopus)

• Urinary exposure marker discovery for toxicants using ultra-high pressure liquid chromatography coupled with Orbitrap high resolution mass spectrometry and three untargeted metabolomics approaches

  Hsu, J. Y., Hsu, J. F., Chen, Y. R., Shih, C. L., Hsu, Y. S., Chen, Y. J., Tsai, S. H. & Liao, P. C., 2016 Oct 5, In: Analytica Chimica Acta. 939, p. 73-83 11 p.

  Research output: Contribution to journal › Article › peer-review

  • High pressure liquid chromatography
  • Metabolomics
  • phthalic acid
  • Metabolites
  • Mass spectrometry
  10 Citations (Scopus)
• 2014

  Detection and distribution of endogenous steroids in human stratum corneum

  Tseng, S. P., Lu, C-C., Liao, P-C., Chou, C-H., Sheu, H. M. & Tsai, J-C., 2014 Mar 1, In: Dermatologica Sinica. 32, 1, p. 19-24 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Cortisone
  • Cornea
  • Steroids
  • Hydrocortisone
  • Forearm
  2 Citations (Scopus)

• iPhos: A toolkit to streamline the alkaline phosphatase-assisted comprehensive LC-MS phosphoproteome investigation

  Yang, T. H., Chang, H. T., Hsiao, E. S. L., Sun, J. L., Wang, C. C., Wu, H. Y., Liao, P. C. & Wu, W. S., 2014 Dec 8, In: BMC Bioinformatics. 15, 16, S10.

  Research output: Contribution to journal › Article › peer-review

  • Phosphatases
  • Mass Spectrometry
  • Liquid chromatography
  • Chromatography
  • Mass spectrometry
  4 Citations (Scopus)

• Label-free proteomic analysis of environmental acidification-influenced Streptococcus pyogenes secretome reveals a novel acid-induced protein histidine triad protein A (HtpA) involved in necrotizing fasciitis

  Wen, Y. T., Wang, J. S., Tsai, S. H., Chuan, C. N., Wu, J. J. & Liao, P. C., 2014 Sep 23, In: Journal of Proteomics. 109, p. 90-103 14 p.

  Research output: Contribution to journal › Article › peer-review

  • histidine triad protein
  • Acidification
  • Necrotizing Fasciitis
  • Proteomics
  • Streptococcus pyogenes
  13 Citations (Scopus)

• Risk for estrogen-dependent diseases in relation to phthalate exposure and polymorphisms of CYP17A1 and estrogen receptor genes

  Huang, P. C., Li, W. F., Liao, P. C., Sun, C. W., Tsai, E. M. & Wang, S. L., 2014 Nov 19, In: Environmental Science and Pollution Research. 21, 24, p. 13964-13973 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogens
  • phthalic acid
  • Polymorphism
  • phthalate
  • Estrogen Receptor alpha
  25 Citations (Scopus)

• Sex steroid hormone levels and reproductive development of eight-year-old children following in utero and environmental exposure to phthalates

  Su, P. H., Chen, J. Y., Lin, C. Y., Chen, H. Y., Liao, P. C., Ying, T. H. & Wang, S. L., 2014 Sep, In: PloS one. 9, 9, ee102788.

  Research output: Contribution to journal › Article › peer-review

  • phthalic acid
  • maternal exposure
  • environmental exposure
  • phthalates
  • sex hormones
  15 Citations (Scopus)

• Small GTPase Rab37 targets tissue inhibitor of metalloproteinase 1 for exocytosis and thus suppresses tumour metastasis

  Tsai, C. H., Cheng, H. C., Wang, Y. S., Lin, P., Jen, J., Kuo, I. Y., Chang, Y. H., Liao, P. C., Chen, R. H., Yuan, W. C., Hsu, H. S., Yang, M. H., Hsu, M. T., Wu, C. Y. & Wang, Y. C., 2014 Sep 3, In: Nature communications. 5, 4804.

  Research output: Contribution to journal › Article › peer-review

  • metastasis
  • Tissue Inhibitor of Metalloproteinase-1
  • Monomeric GTP-Binding Proteins
  • inhibitors
  • Exocytosis
  26 Citations (Scopus)
• 2012

  Biochemical study of retired pentachlorophenol workers with and without following dietary exposure to PCDD/Fs

  Chang, J. W., Chen, H. L., Su, H. J., Liao, P. C. & Lee, C. C., 2012 Aug 1, In: Chemosphere. 88, 7, p. 813-819 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Pentachlorophenol
  • Dietary Exposure
  • Lipids
  • Polychlorinated Dibenzodioxins
  • PCP
  5 Citations (Scopus)

• Coexposure of dioxin-like polychlorinated biphenyls and polychlorinated dibenzo-p-dioxins and dibenzofurans in free-range hens and implications derived from congener profile analysis

  Lin, C., Hsu, J. F. & Liao, P-C., 2012 Feb 29, In: Journal of Agricultural and Food Chemistry. 60, 8, p. 1963-1972 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Dibenzofurans
  • dibenzofuran
  • polychlorinated dibenzodioxins
  • Dioxins
  • Polychlorinated Dibenzodioxins
  9 Citations (Scopus)

• Comparative secretome analyses using a hollow fiber culture system with label-free quantitative proteomics indicates the influence of PARK7 on cell proliferation and migration/invasion in lung adenocarcinoma

  Chang, Y. H., Lee, S. H., Chang, H. C., Tseng, Y. L., Lai, W. W., Liao, C. C., Tsay, Y. G. & Liao, P. C., 2012 Nov 2, In: Journal of Proteome Research. 11, 11, p. 5167-5185 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Cell proliferation
  • Proteomics
  • Adenocarcinoma of Lung
  • Labels
  • Protein Deglycase DJ-1
  15 Citations (Scopus)

• Dietary intake of PCDD/Fs and dioxin-like PCBs from fresh foods around Taiwan

  Chang, J. W., Liao, P. C. & Lee, C. C., 2012 Dec 1, In: Journal of Food and Drug Analysis. 20, 4, p. 805-813+982

  Research output: Contribution to journal › Article › peer-review

  • polychlorinated dibenzodioxins
  • Dioxins
  • raw foods
  • Polychlorinated Dibenzodioxins
  • Polychlorinated Biphenyls
  7 Citations (Scopus)

• Impact of uremic environment on peritoneum: A proteomic view

  Wang, H. Y., Lin, C. Y., Chien, C. C., Kan, W. C., Tian, Y. F., Liao, P. C., Wu, H. Y. & Su, S. B., 2012 Apr 3, In: Journal of Proteomics. 75, 7, p. 2053-2063 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Peritoneum
  • Uremia
  • Proteins
  • Ascitic Fluid
  9 Citations (Scopus)

• METHOD FOR ANALYZING SECRETOME, BIOMARKER FOR LUNG CANCER METASTASIS, AND siRNA COMPOUND FOR INHIBITING LUNG CANCER METASTASIS

  Liao, P-C., 2012 Oct 25, Patent No. 8912155

  Research output: Patent

  • Proteome
  • Small Interfering RNA
  • Lung Neoplasms
  • Biomarkers
  • Neoplasm Metastasis

• Patents and the development on polymer based nanomaterial (PAMAM dendrimer) for biomedical applications

  Rajasekhar, D. & Liao, P. C., 2012 Jan 1, In: Recent Patents on Biomedical Engineering. 5, 2, p. 159-174 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Dendrimers
  • Poly(amidoamine)
  • Nanostructured materials
  • Patents
  • Nanostructures
  2 Citations (Scopus)

• Proteomics Investigation Reveals Apoptosis-Associated Proteins in Aryl Hydrocarbon Receptor-Deficient Human Lung Cells Treated with 2,3,7,8-Tetrachlorobenzo-p-Dioxin

  Hsiao, E. S. L., Chang, Y. W., Lin, P. & Liao, P. C., 2012, In: Journal of Proteomics and Bioinformatics. 5, 1, p. 15-23 9 p.

  Research output: Contribution to journal › Article › peer-review

  • human AHR protein
  • 1,4-dioxin
  • Cell death
  • Proteomics
  • Aryl Hydrocarbon Receptors
  1 Citation (Scopus)

• Secretomic analysis identifies alpha-1 antitrypsin (A1AT) as a required protein in cancer cell migration, invasion, and pericellular fibronectin assembly for facilitating lung colonization of lung adenocarcinoma cells

  Chang, Y. H., Lee, S. H., Liao, I. C., Huang, S. H., Cheng, H. C. & Liao, P. C., 2012 Nov, In: Molecular and Cellular Proteomics. 11, 11, p. 1320-1339 20 p.

  Research output: Contribution to journal › Article › peer-review

  • alpha 1-Antitrypsin
  • Adenocarcinoma of Lung
  • Fibronectins
  • Cells
  • Cell Movement
  41 Citations (Scopus)
• 2011

  An occupational exposure assessment of polychlorinated dibenzo-p-dioxin and dibenzofurans in firefighters

  Hsu, J. F., Guo, H. R., Wang, H. W., Liao, C. K. & Liao, P. C., 2011 May 1, In: Chemosphere. 83, 10, p. 1353-1359 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Dibenzofurans
  • Firefighters
  • Polychlorinated Dibenzodioxins
  • dibenzofuran
  • occupational exposure
  18 Citations (Scopus)

• Antibacterial activity of poloxamer-modified montmorillonite clay against E. coli

  Nien, Y. T., Liao, Y. H. & Liao, P. C., 2011 Oct 1, In: Materials Letters. 65, 19-20, p. 3092-3094 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Bentonite
  • Clay
  • Clay minerals
  • Poloxamer
  • montmorillonite
  16 Citations (Scopus)

• Associations between maternal phthalate exposure and cord sex hormones in human infants

  Lin, L. C., Wang, S. L., Chang, Y. C., Huang, P. C., Cheng, J. T., Su, P. H. & Liao, P. C., 2011 May, In: Chemosphere. 83, 8, p. 1192-1199 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Steroid hormones
  • sex hormone
  • Hormones
  • phthalic acid
  • Maternal Exposure
  79 Citations (Scopus)

• Collection of in vivo-like liver cell secretome with alternative sample enrichment method using a hollow fiber bioreactor culture system combined with tangential flow filtration for secretomics analysis

  Wen, Y. T., Chang, Y. C., Lin, L. C. & Liao, P. C., 2011 Jan 17, In: Analytica Chimica Acta. 684, 1-2, p. 81-88 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Bioreactors
  • Liver
  • bioreactor
  • fiber
  • Fibers
  11 Citations (Scopus)

• Differential secretomics of Streptococcus pyogenes reveals a novel peroxide regulator (PerR)-regulated extracellular virulence factor mitogen factor3 (MF3)

  Wen, Y. T., Tsou, C. C., Kuo, H. T., Wang, J. S., Wu, J. J. & Liao, P. C., 2011 Sep, In: Molecular and Cellular Proteomics. 10, 9

  Research output: Contribution to journal › Article › peer-review

  • Peroxides
  • Streptococcus pyogenes
  • Virulence Factors
  • Mitogens
  • Virulence
  15 Citations (Scopus)

• Identification of di-isononyl phthalate metabolites for exposure marker discovery using in vitro/In vivo metabolism and signal mining strategy with LC-MS data

  Hsu, J. F., Peng, L. W., Li, Y. J., Lin, L. C. & Liao, P. C., 2011 Nov 15, In: Analytical chemistry. 83, 22, p. 8725-8731 7 p.

  Research output: Contribution to journal › Article › peer-review

  • phthalic acid
  • Metabolites
  • Metabolism
  • Esters
  • Isotopes
  11 Citations (Scopus)

• Identification of hnRNPH1, NF45, and C14orf166 as novel host interacting partners of the mature hepatitis C virus core protein

  Lee, J. W., Liao, P. C., Young, K. C., Chang, C. L., Chen, S. S. L., Chang, T. T., Lai, M. D. & Wang, S. W., 2011 Oct 7, In: Journal of Proteome Research. 10, 10, p. 4522-4534 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Hepatitis C virus nucleocapsid protein
  • Heterogeneous-Nuclear Ribonucleoproteins
  • Cytoplasm
  • Nuclear Factor 45 Protein
  • Proteins
  30 Citations (Scopus)

• Predicting the risk of cardiovascular disease in people exposed to moderate to high levels of dioxin

  Chang, J. W., Chen, H-L., Chang, C-C., Su, H-J., Liao, P-C. & Lee, C-C., 2011 Dec 30, In: Journal of Hazardous Materials. 198, p. 317-322 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Dioxins
  • cardiovascular disease
  • dioxin
  • Cardiovascular Diseases
  • serum
  3 Citations (Scopus)

• Protein tyrosine phosphatase non-receptor type 14 is a novel sperm-motility biomarker.

  Chao, H. C. A., Chung, C. L., Pan, H. A., Liao, P. C., Kuo, P. L. & Hsu, C. C., 2011 Sep, In: Journal of assisted reproduction and genetics. 28, 9, p. 851-861 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Non-Receptor Protein Tyrosine Phosphatases
  • Sperm Motility
  • Spermatozoa
  • Biomarkers
  • Proteins
  12 Citations (Scopus)

• Quantitative secretome analysis reveals that COL6A1 is a metastasis-associated protein using stacking gel-aided purification combined with iTRAQ labeling

  Chiu, K. H., Chang, Y. H., Wu, Y. S., Lee, S. H. & Liao, P. C., 2011 Mar 4, In: Journal of Proteome Research. 10, 3, p. 1110-1125 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Purification
  • Labeling
  • Gels
  • Chemical analysis
  • Neoplasm Metastasis
  50 Citations (Scopus)

• Simultaneous detection of nine cyanotoxins in drinking water using dual solid-phase extraction and liquid chromatography-mass spectrometry

  Yen, H. K., Lin, T. F. & Liao, P. C., 2011 Aug 1, In: Toxicon. 58, 2, p. 209-218 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Liquid chromatography
  • Solid Phase Extraction
  • Mass spectrometry
  • cylindrospermopsin
  • Liquid Chromatography
  50 Citations (Scopus)

• Simultaneous exposure of non-diabetics to high levels of dioxins and mercury increases their risk of insulin resistance

  Chang, J. W., Chen, H. L., Su, H. J., Liao, P. C., Guo, H. R. & Lee, C. C., 2011 Jan 30, In: Journal of Hazardous Materials. 185, 2-3, p. 749-755 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Insulin
  • Dioxins
  • Mercury
  • dioxin
  • Blood
  54 Citations (Scopus)

• Urinary protein profiling by liquid chromatography/tandem mass spectrometry: ADAM28 is overexpressed in bladder transitional cell carcinoma

  Tyan, Y. C., Yang, M. H., Chen, S. C. J., Jong, S. B., Chen, W. C., Yang, Y. H., Chung, T. W. & Liao, P. C., 2011 Oct 15, In: Rapid Communications in Mass Spectrometry. 25, 19, p. 2851-2862 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Liquid chromatography
  • Mass spectrometry
  • Cells
  • Proteomics
  • Serine Peptidase Inhibitor Kazal-Type 5
  18 Citations (Scopus)