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  • Wen-Chien Ko
24 Citations (Scopus)

Impact of inappropriate empirical antibiotic therapy on outcome of bacteremic adults visiting the ED

Lee, C. C., Lee, C-H., Chuang, M. C., Hong, M-Y., Hsu, H-C. & Ko, W-C., 2012 Jan 1, In : American Journal of Emergency Medicine. 30, 8, p. 1447-1456 10 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Impact of revised CLSI breakpoints for susceptibility to third-generation cephalosporins and carbapenems among Enterobacteriaceae isolates in the Asia-Pacific region: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2002-2010

Huang, C. C., Chen, Y. S., Toh, H. S., Lee, Y. L., Liu, Y. M., Ho, C. M., Lu, P. L., Liu, C. E., Chen, Y. H., Wang, J. H., Tang, H. J., Yu, K. W., Liu, Y. C., Chuang, Y. C., Xu, Y., Ni, Y., Ko, W. C. & Hsueh, P. R., 2012 Jun 1, In : International journal of antimicrobial agents. 40, SUPPL. 1, p. S4-S10

Research output: Contribution to journalArticle

31 Citations (Scopus)
13 Citations (Scopus)

Impact of toxigenic clostridium difficile colonization and infection among hospitalized adults at a district hospital in Southern Taiwan

Hung, Y. P., Tsai, P. J., Hung, K. H., Liu, H. C., Lee, C. I., Lin, H. J., Wu, Y. H., Wu, J. J. & Ko, W. C., 2012 Aug 2, In : PloS one. 7, 8, e42415.

Research output: Contribution to journalArticle

44 Citations (Scopus)
3 Citations (Scopus)

Implementation of a national bundle care program to reduce catheter-associated urinary tract infection in high-risk units of hospitals in Taiwan

for the & Infection Control Society of Taiwan, 2017 Aug, In : Journal of Microbiology, Immunology and Infection. 50, 4, p. 464-470 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Implementation of a national bundle care program to reduce central line-associated bloodstream infections in intensive care units in Taiwan

for the Infection Control Society of Taiwan, 2018 Oct, In : Journal of Microbiology, Immunology and Infection. 51, 5, p. 666-671 6 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Implementation of a national quality improvement program to enhance hand hygiene in nursing homes in Taiwan

for Infection Control Society of Taiwan, 2019 Apr, In : Journal of Microbiology, Immunology and Infection. 52, 2, p. 345-351 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Improved outcome of Pneumocystis pneumonia by early treatment

Lee, N. Y., Chang, C. M., Lee, C. C., Lee, H. C., Li, M. C. & Ko, W. C., 2012 Apr 1, In : Journal of Microbiology, Immunology and Infection. 45, 2, p. 163-164 2 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)

Incidence of Aeromonas bacteremia in southern Taiwan: Vibrio and Salmonella bacteremia as comparators

Wu, C. J., Chen, P. L., Tang, H. J., Chen, H. M., Tseng, F. C., Shih, H. I., Hung, Y. P., Chung, C. H. & Ko, W. C., 2014 Apr, In : Journal of Microbiology, Immunology and Infection. 47, 2, p. 145-148 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Incidence of Neurological Disorders among HIV-Infected Individuals with Universal Health Care in Taiwan from 2000 to 2010

Tsai, Y. T., Chen, Y. C., Hsieh, C. Y., Ko, W. C. & Ko, N. Y., 2017 Aug 15, In : Journal of Acquired Immune Deficiency Syndromes. 75, 5, p. 509-516 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Increased repeat syphilis among HIV-infected patients: A nationwide population-based cohort study in Taiwan

Lee, N. Y., Chen, Y. C., Liu, H. Y., Li, C-Y., Li, C. W., Ko, W. C. & Ko, N. Y., 2020 Jul 10, In : Medicine. 99, 28, p. e21132

Research output: Contribution to journalArticle

Open Access

Increasing cytomegalovirus detection rate from respiratory tract specimens by a new laboratory-developed automated molecular diagnostic test

Tsai, H. P., Yeh, C. S., Lin, I. T., Ko, W. C. & Wang, J. R., 2020 Jul, In : Microorganisms. 8, 7, p. 1-12 12 p., 1063.

Research output: Contribution to journalArticle

Open Access

Increasing resistance to fluoroquinolones among Haemophilus species in Southern Taiwan

Chang, C. M., Tang, H. J., Wang, L. R., Shih, H. I., Huang, C. C., Lee, N. Y., Lee, C. C. & Ko, W. C., 2017 Apr, In : Journal of Microbiology, Immunology and Infection. 50, 2, p. 258-260 3 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

In vitro activity of ceftazidime–avibactam, ceftolozane–tazobactam, and other comparable agents against clinically important Gram-negative bacilli: Results from the 2017 surveillance of multicenter antimicrobial resistance in Taiwan (SMART)

Jean, S. S., Lu, M. C., Shi, Z. Y., Tseng, S. H., Wu, T. S., Lu, P. L., Shao, P. L., Ko, W. C., Wang, F. D. & Hsueh, P. R., 2018, In : Infection and Drug Resistance. 11, p. 1983-1992 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
Open Access

In vitro and in vivo antibacterial activity of tigecycline against Vibrio vulnificus

Tang, H. J., Chen, C. C., Lai, C. C., Zhang, C. C., Weng, T. C., Chiu, Y. H., Toh, H. S., Chiang, S. R., Yu, W. L., Ko, W. C. & Chuang, Y. C., 2018 Feb, In : Journal of Microbiology, Immunology and Infection. 51, 1, p. 76-81 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

In vitro and in vivo intracellular killing effects of tigecycline against clinical nontyphoid Salmonella isolates using ceftriaxone as a comparator

Tang, H. J., Ko, W. C., Chen, C. C., Chen, P. L., Toh, H. S., Weng, T. C., Yu, W. L., Chiang, S. R. & Chuang, Y. C., 2011 Jun, In : Antimicrobial agents and chemotherapy. 55, 6, p. 2755-2759 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

In vitro diagnostics of coronavirus disease 2019: Technologies and application

Lai, C. C., Wang, C. Y., Ko, W. C. & Hsueh, P. R., 2020, (Accepted/In press) In : Journal of Microbiology, Immunology and Infection.

Research output: Contribution to journalReview article

Open Access
13 Citations (Scopus)

In Vitro efficacies and resistance profiles of rifampin-based combination regimens for biofilm-embedded methicillin-resistant Staphylococcus aureus

Tang, H. J., Chen, C. C., Cheng, K. C., Wu, K. Y., Lin, Y. C., Zhang, C. C., Weng, T. C., Yu, W. L., Chiu, Y. H., Toh, H. S., Chiang, S. R., Su, B. A., Ko, W. C. & Chuang, Y. C., 2013 Nov, In : Antimicrobial agents and chemotherapy. 57, 11, p. 5717-5720 4 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)
33 Citations (Scopus)

In vitro efficacy of fosfomycin-based combinations against clinical vancomycin-resistant Enterococcus isolates

Tang, H. J., Chen, C. C., Zhang, C. C., Su, B. A., Li, C. M., Weng, T. C., Chiang, S. R., Ko, W-C. & Chuang, Y. C., 2013 Nov 1, In : Diagnostic Microbiology and Infectious Disease. 77, 3, p. 254-257 4 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

In vitro efficacy of fosfomycin-containing regimens against methicillin-resistant Staphylococcus aureus in biofilms

Tang, H. J., Chen, C. C., Cheng, K. C., Toh, H. S., Su, B. A., Chiang, S. R., Ko, W. C. & Chuang, Y. C., 2012 Apr 1, In : Journal of Antimicrobial Chemotherapy. 67, 4, p. 944-950 7 p., dkr535.

Research output: Contribution to journalArticle

45 Citations (Scopus)

In vitro susceptibilities of non-Enterobacteriaceae isolates from patients with intra-abdominal infections in the Asia-Pacific region from 2003 to 2010: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART)

Liu, Y. M., Chen, Y. S., Toh, H. S., Huang, C. C., Lee, Y. L., Ho, C. M., Lu, P. L., Ko, W. C., Chen, Y. H., Wang, J. H., Tang, H. J., Yu, K. W., Liu, Y. C., Chuang, Y. C., Xu, Y., Ni, Y., Liu, C. E. & Hsueh, P. R., 2012 Jun 1, In : International journal of antimicrobial agents. 40, SUPPL. 1, p. S11-S17

Research output: Contribution to journalArticle

28 Citations (Scopus)
Open Access
7 Citations (Scopus)

Jarisch-Herxheimer reaction among HIV-positive patients with early syphilis: Azithromycin versus benzathine penicillin G therapy

Tsai, M. S., Yang, C. J., Lee, N. Y., Hsieh, S. M., Lin, Y. H., Sun, H. Y., Sheng, W. H., Lee, K. Y., Yang, S. P., Liu, W. C., Wu, P. Y., Ko, W. C. & Hung, C. C., 2014, In : Journal of the International AIDS Society. 17, 18993.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model

Yang, H. T., Chen, J. W., Rathod, J., Jiang, Y. Z., Tsai, P. J., Hung, Y. P., Ko, W. C., Paredes-Sabja, D. & Huang, I. H., 2018 Jan 17, In : Frontiers in Microbiology. 8, JAN, 2635.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Legionnaires’ disease at a medical center in southern Taiwan

Hung, T. L., Li, M. C., Wang, L. R., Liu, C. C., Li, C. W., Chen, P. L., Syue, L. S., Lee, N. Y. & Ko, W. C., 2018 Jun, In : Journal of Microbiology, Immunology and Infection. 51, 3, p. 352-358 7 p.

Research output: Contribution to journalArticle

Less severe but prolonged course of acute hepatitis a in Human Immunodeficiency Virus (HIV)-infected patients compared with HIV-uninfected patients during an outbreak: A multicenter observational study

Lee, Y. L., Chen, G. J., Chen, N. Y., Liou, B. H., Wang, N. C., Lee, Y. T., Yang, C. J., Huang, Y. S., Tang, H. J., Huang, S. S., Lin, Y. C., Cheng, C. Y., Lee, C. H., Chen, T. C., Wu, T. S., Liu, C. E., Lu, P. L., Hung, C. C., Lee, Y. C., Cheng, C. Y. & 22 others, Cheng, S. H., Huang, Y. S., Lee, Y. T., Lin, C. C., Lin, S. P., Hsieh, C. Y., Wang, H. W., Ho, M. W., Liu, C. E., Lee, Y. L., Lee, Y. C., Tang, H. J., Ku, H. C., Li, C. W., Lee, N. Y., Ko, W. C., Lu, P. L., Chen, Y. H., Lin, H. H., Huang, W. C., Lee, C. H. & Che, T. C., 2018 Oct 30, In : Clinical Infectious Diseases. 67, 10, p. 1595-1602 8 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Low papanicolaou smear screening rate of women with hiv infection: A nationwide population-based study in Taiwan, 2000-2010

Chen, Y. C., Liu, H. Y., Li, C. Y., Lee, N. Y., Ko, W. C., Chou, C. Y., Hsieh, T. H. & Ko, N. Y., 2013 Dec 1, In : Journal of Women's Health. 22, 12, p. 1016-1022 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Low seroprevalence of Zika virus infection among adults in Southern Taiwan

Chien, Y. W., Ho, T. C., Huang, P. W., Ko, N. Y., Ko, W. C. & Perng, G. C., 2019 Oct 23, In : BMC infectious diseases. 19, 1, 884.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Matrix-assisted laser desorption ionization-time of flight mass spectrometry can accurately differentiate Aeromonas dhakensis from A. hydrophila, A. caviae, and A. veronii

Chen, P. L., Lee, T. F., Wu, C. J., Teng, S. H., Teng, L. J., Ko, W. C. & Hsueh, P. R., 2014 Jul, In : Journal of Clinical Microbiology. 52, 7, p. 2625-2628 4 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Mediating effects of social support on depression and quality of life among patients with HIV infection in Taiwan

Hou, W. L., Chen, C. E., Liu, H. Y., Lai, Y. Y., Lee, H. C., Lee, N. Y., Chang, C. M., Chen, P. L., Ko, W. C., Shu, B. C. & Ko, N. Y., 2014 Aug 3, In : AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. 26, 8, p. 996-1003 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Membrane Cholesterol Is Crucial for Clostridium difficile Surface Layer Protein Binding and Triggering Inflammasome Activation

Chen, Y., Huang, K., Chen, L. K., Wu, H. Y., Hsu, C. Y., Tsai, Y. S., Ko, W. C. & Tsai, P. J., 2020 Jul 31, In : Frontiers in Immunology. 11, 1675.

Research output: Contribution to journalArticle

Open Access

Metastatic complications of pericarditis and cardiac tamponade as a result of Staphylococcus aureus bacteremia developing during antimicrobial therapy

Shih, H. I., Wu, C. J., Chi, C. Y., Lee, H. C., Lauderdale, T. L. Y., Lin, Y. T., Lin, C. C., Lee, N. Y., Chang, C. M. & Ko, W. C., 2013 Feb 13, In : Internal Medicine. 52, 3, p. 389-391 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Methicillin-resistant Staphylococcus aureus sequence type 45 with high rates of ciprofloxacin and tetracycline resistance in the residents and environments of long-term care facilities in Taiwan

Lai, C. C., Lee, C. M., Chiang, H. T., Lu, M. C., Wang, L. F., Tsai, T. L., Kang, M. Y., Jan, Y. N., Lo, Y. T., Ko, W. C., Tseng, S. H. & Hsueh, P. R., 2018 Mar, In : Journal of Infection. 76, 3, p. 305-307 3 p.

Research output: Contribution to journalLetter

4 Citations (Scopus)

Molecular epidemiology and antimicrobial resistance of methicillin- resistant Staphylococcus aureus bloodstream isolates in Taiwan, 2010

Chen, C. J., Huang, Y. C., Su, L. H., Wu, T. L., Huang, S. H., Chien, C. C., Chen, P. Y., Lu, M. C. & Ko, W. C., 2014 Jun 26, In : PloS one. 9, 6, e101184.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Monomicrobial Aeromonas and Vibrio bacteremia in cirrhotic adults in southern Taiwan: Similarities and differences

Syue, L-S., Chen, P-L., Wu, C. J., Lee, N-Y., Lee, C. C., Li, C-W., Li, M-C., Tang, H. J., Hsueh, P. R. & Ko, W-C., 2016 Aug 1, In : Journal of Microbiology, Immunology and Infection. 49, 4, p. 509-515 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Multicenter evaluation of two chemiluminescence and three lateral flow immunoassays for the diagnosis of COVID-19 and assessment of antibody dynamic responses to SARS-CoV-2 in Taiwan

Chen, S. Y., Lee, Y. L., Lin, Y. C., Lee, N. Y., Liao, C. H., Hung, Y. P., Lu, M. C., Wu, J. L., Tseng, W. P., Lin, C. H., Chung, M. Y., Kang, C. M., Lee, Y. F., Lee, T. F., Cheng, C. Y., Chen, C. P., Huang, C. H., Liu, C. E., Cheng, S. H., Ko, W. C. & 2 others, Hsueh, P. R. & Chen, S. C., 2020 Jan 1, In : Emerging Microbes and Infections. 9, 1, p. 2157-2168 12 p.

Research output: Contribution to journalArticle

Open Access

Multicenter study in Taiwan of the in Vitro activities of nemonoxacin, tigecycline, doripenem, and other antimicrobial agents against clinical isolates of various Nocardia species

Lai, C. C., Liu, W. L., Ko, W. C., Chen, Y. H., Tan, H. R., Huang, Y. T. & Hsueh, P. R., 2011 May, In : Antimicrobial agents and chemotherapy. 55, 5, p. 2084-2091 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Multicenter study of azole-resistant aspergillus fumigatus clinical isolates, Taiwan

Wu, C. J., Liu, W. L., Lai, C. C., Chao, C. M., Ko, W. C., Wang, H. C., Dai, C. T., Hsieh, M. I., Choi, P. C., Yang, J. L. & Chen, Y. C., 2020 Apr, In : Emerging infectious diseases. 26, 4, p. 806-809 4 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Multicentre surveillance of prevalence of the 23S rRNA A2058G and A2059G point mutations and molecular subtypes of Treponema pallidum in Taiwan, 2009-2013

Wu, B. R., Yang, C. J., Tsai, M. S., Lee, K. Y., Lee, N. Y., Huang, W. C., Wu, H., Lee, C. H., Chen, T. C., Ko, W. C., Lin, H. H., Lu, P. L., Chen, Y. H., Liu, W. C., Yang, S. P., Wu, P. Y., Su, Y. C., Hung, C. C. & Chang, S. Y., 2014 Aug, In : Clinical Microbiology and Infection. 20, 8, p. 802-807 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Multiple brain abscesses due to aspergillus fumigatus in a patient with liver cirrhosis: A case report

Tang, H. J., Liu, W. L., Chang, T. C., Li, M. C., Ko, W. C., Wu, C. J., Chuang, Y. C. & Lai, C. C., 2016 Mar 4, In : Medicine (United States). 95, 9, e2813.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Murine typhus in Southern Taiwan during 1992-2009

Chang, K., Chen, Y. H., Lee, N. Y., Lee, H. C., Lin, C. Y., Tsai, J. J., Lu, P. L., Chen, T. C., Hsieh, H. C., Lin, W. R., Lai, P. C., Chang, C. M., Wu, C. J., Lai, C. H. & Ko, W. C., 2012 Jul 1, In : American Journal of Tropical Medicine and Hygiene. 87, 1, p. 141-147 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Nanoparticles in the treatment of infections caused by multidrug-resistant organisms

Lee, N. Y., Ko, W. C. & Hsueh, P. R., 2019, In : Frontiers in Pharmacology. 10, 1153.

Research output: Contribution to journalReview article

Open Access
17 Citations (Scopus)

National bundle care program implementation to reduce ventilator-associated pneumonia in intensive care units in Taiwan

for the Infection Control Society of Taiwan, 2019 Aug, In : Journal of Microbiology, Immunology and Infection. 52, 4, p. 592-597 6 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

National Surveillance of Antimicrobial Susceptibility of Bacteremic Gram-Negative Bacteria with Emphasis on Community-Acquired Resistant Isolates: Report from the 2019 Surveillance of Multicenter Antimicrobial Resistance in Taiwan (SMART)

Liu, P. Y., Lee, Y. L., Lu, M. C., Shao, P. L., Lu, P. L., Chen, Y. H., Cheng, S. H., Ko, W. C., Lin, C. Y., Wu, T. S., Yen, M. Y., Wang, L. S., Liu, C. P., Lee, W. S., Chen, Y. S., Wang, F. D., Tseng, S. H., Lin, C. N., Tang, H. J., Chen, Y. H. & 4 others, Sheng, W. H., Lee, C. M., Liao, M. H. & Hsueh, P. R., 2020 Sep 21, In : Antimicrobial agents and chemotherapy. 64, 10

Research output: Contribution to journalArticle