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2020

Comparative treatment outcomes for patients with idiopathic subglottic stenosis

Gelbard, A., Anderson, C., Berry, L. D., Amin, M. R., Benninger, M. S., Blumin, J. H., Bock, J. M., Bryson, P. C., Castellanos, P. F., Chen, S. C., Clary, M. S., Cohen, S. M., Crawley, B. K., Dailey, S. H., Daniero, J. J., De Alarcon, A., Donovan, D. T., Edell, E. S., Ekbom, D. C., Fernandes-Taylor, S. & 55 others, Fink, D. S., Franco, R. A., Garrett, C. G., Guardiani, E. A., Hillel, A. T., Hoffman, H. T., Hogikyan, N. D., Howell, R. J., Huang, L. C., Hussain, L. K., Johns, M. M., Kasperbauer, J. L., Khosla, S. M., Kinnard, C., Kupfer, R. A., Langerman, A. J., Lentz, R. J., Lorenz, R. R., Lott, D. G., Lowery, A. S., Makani, S. S., Maldonado, F., Mannion, K., Matrka, L., McWhorter, A. J., Merati, A. L., Mori, M. C., Netterville, J. L., ODell, K., Ongkasuwan, J., Postma, G. N., Reder, L. S., Rohde, S. L., Richardson, B. E., Rickman, O. B., Rosen, C. A., Rutter, M. J., Sandhu, G. S., Schindler, J. S., Schneider, G. T., Shah, R. N., Sikora, A. G., Sinard, R. J., Smith, M. E., Smith, L. J., Soliman, A. M. S., Sveinsdóttir, S., Van Daele, D. J., Veivers, D., Verma, S. P., Weinberger, P. M., Weissbrod, P. A., Wootten, C. T., Shyr, Y. & Francis, D. O., 2020 Jan, In : JAMA Otolaryngology - Head and Neck Surgery. 146, 1, p. 20-29 10 p.

Research output: Contribution to journalArticle

Open Access
Pathologic Constriction
Dilatation
Rare Diseases
Recurrence
Therapeutics

Immune-Related Adverse Events and Immune Checkpoint Inhibitor Efficacy in Patients with Gastrointestinal Cancer with Food and Drug Administration-Approved Indications for Immunotherapy

Das, S., Ciombor, K. K., Haraldsdottir, S., Pumpalova, Y., Sahin, I. H., Pineda, G., Shyr, Y., Lin, E. P., Hsu, C. Y., Chu, S. K., Goff, L. W., Cardin, D. B., Bilen, M. A., Fisher, G. A., Wu, C. & Berlin, J., 2020 Jan 1, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Open Access
Gastrointestinal Neoplasms
United States Food and Drug Administration
Immunotherapy
Disease-Free Survival
Biomarkers

Kidney Stone History and Adverse Outcomes After Percutaneous Coronary Intervention

Lai, C. H., Huang, L. C., Holby, S. N., Lai, Y. J., Su, P. F., Cheng, Y. S., Shyr, Y. & Hsi, R. S., 2020 Feb, In : Urology. 136, p. 75-81 7 p.

Research output: Contribution to journalArticle

Kidney Calculi
Percutaneous Coronary Intervention
Hospital Mortality
Odds Ratio
Myocardial Infarction
2019
7 Citations (Scopus)

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

Formisano, L., Lu, Y., Servetto, A., Hanker, A. B., Jansen, V. M., Bauer, J. A., Sudhan, D. R., Guerrero-Zotano, A. L., Croessmann, S., Guo, Y., Ericsson, P. G., Lee, K. M., Nixon, M. J., Schwarz, L. J., Sanders, M. E., Dugger, T. C., Cruz, M. R., Behdad, A., Cristofanilli, M., Bardia, A. & 11 others, O’Shaughnessy, J., Nagy, R. J., Lanman, R. B., Solovieff, N., He, W., Miller, M., Su, F., Shyr, Y., Mayer, I. A., Balko, J. M. & Arteaga, C. L., 2019 Dec 1, In : Nature communications. 10, 1, 1373.

Research output: Contribution to journalArticle

Open Access
breast
inhibitors
cancer
Breast Neoplasms
Protein-Tyrosine Kinases
3 Citations (Scopus)

beRBP: binding estimation for human RNA-binding proteins

Yu, H., Wang, J., Sheng, Q., Liu, Q. & Shyr, Y., 2019 Mar 18, In : Nucleic acids research. 47, 5, p. e26

Research output: Contribution to journalArticle

Open Access
RNA-Binding Proteins
RNA
Benchmarking
Protein Binding

Erratum for the research article: Genomic proling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance (Science Translational Medicine DOI: 10.1126/scitranslmed.aai7993)

Giltnane, J. M., Hutchinson, K. E., Stricker, T. P., Formisano, L., Young, C. D., Estrada, M. V., Nixon, M. J., Du, L., Sanchez, V., Ericsson, P. G., Kuba, M. G., Sanders, M. E., Mu, X. J., Van Allen, E. M., Wagle, N., Mayer, I. A., Abramson, V., Gόmez, H., Rizzo, M., Toy, W. & 15 others, Chandarlapaty, S., Mayer, E. L., Christiansen, J., Murphy, D., Fitzgerald, K., Wang, K., Ross, J. S., Miller, V. A., Stephens, P. J., Yelensky, R., Garraway, L., Shyr, Y., Meszoely, I., Balko, J. M. & Arteaga, C. L., 2019 Feb 13, In : Science Translational Medicine. 11, 479, eaaw7620.

Research output: Contribution to journalComment/debate

Translational Medical Research
Estrogens
Breast Neoplasms
Research

Establishing and Evaluating an ASCO Learning Cohort: a Longitudinal Project Assessing the Learning Needs and Behaviors of Oncology Professionals

Manochakian, R., George, T. J., Wood, M., Polansky, M., Baer, A., Grupe, A., Shyr, Y., Wang, C. & Horn, L., 2019 Jan 1, (Accepted/In press) In : Journal of Cancer Education.

Research output: Contribution to journalArticle

Medical Oncology
Learning
Demography
Delivery of Health Care
Continuing Education

Extramedullary leukemia behaving as solid cancer: clinical, histologic, and genetic clues to chemoresistance in organ sites

Cunningham, I., Hamele-Bena, D., Guo, Y., Shiomi, T., Papp, A. C., Chakravarti, B., Yang, J., Shyr, Y. & Fisher, R. A., 2019 Nov 1, In : American Journal of Hematology. 94, 11, p. 1200-1207 8 p.

Research output: Contribution to journalArticle

Leukemia
Neoplasms
Bone Marrow
Breast Neoplasms
Treatment Failure
1 Citation (Scopus)

HACER: An atlas of human active enhancers to interpret regulatory variants

Wang, J., Dai, X., Berry, L. D., Cogan, J. D., Liu, Q. & Shyr, Y., 2019 Jan 8, In : Nucleic acids research. 47, D1, p. D106-D112

Research output: Contribution to journalArticle

Open Access
Atlases
Transcription Factors
Gene Regulatory Networks
Nucleic Acid Regulatory Sequences
Genome-Wide Association Study
3 Citations (Scopus)

Human PAH is characterized by a pattern of lipid-related insulin resistance

Hemnes, A. R., Luther, J. M., Rhodes, C. J., Burgess, J. P., Carlson, J., Fan, R., Fessel, J. P., Fortune, N., Gerszten, R. E., Halliday, S. J., Hekmat, R., Howard, L., Newman, J. H., Niswender, K. D., Pugh, M. E., Robbins, I. M., Sheng, Q., Shibao, C. A., Shyr, Y., Sumner, S. & 7 others, Talati, M., Wharton, J., Wilkins, M. R., Ye, F., Yu, C., West, J. & Brittain, E. L., 2019 Jan 10, In : JCI Insight. 4, 1

Research output: Contribution to journalArticle

Open Access
Pulmonary Hypertension
Insulin Resistance
Lipids
Oxidized LDL Receptors
Lipoproteins
3 Citations (Scopus)

Identification of targetable recurrent MAP3K8 rearrangements in melanomas lacking known driver mutations

Lehmann, B. D., Shaver, T. M., Johnson, D. B., Li, Z., Gonzalez-Ericsson, P. I., Sánchez, V., Shyr, Y., Sanders, M. E. & Pietenpol, J. A., 2019 Jan 1, In : Molecular Cancer Research. 17, 9, p. 1842-1853 12 p.

Research output: Contribution to journalArticle

Melanoma
Mutation
Mitogen-Activated Protein Kinase Kinases
Mitogen-Activated Protein Kinases
Atlases

Income, costs, and health care utilization may influence surgical choice in early stage breast cancer

Sweeting, R. S., Du, L., Shyr, Y. & Hooks, M. A., 2019 Mar 1, In : Breast Journal. 25, 2, p. 334-337 4 p.

Research output: Contribution to journalComment/debate

Palliative Care Referrals for Advanced Non–small-cell Lung Cancer (NSCLC): Patient and Provider Attitudes and Practices

Feld, E., Singhi, E. K., Phillips, S., Huang, L. C., Shyr, Y. & Horn, L., 2019 May 1, In : Clinical Lung Cancer. 20, 3, p. e291-e298

Research output: Contribution to journalArticle

Palliative Care
Non-Small Cell Lung Carcinoma
Referral and Consultation

scRNABatchQC: multi-samples quality control for single cell RNA-seq data

Liu, Q., Sheng, Q., Ping, J., Ramirez, M. A., Lau, K. S., Coffey, R. J. & Shyr, Y., 2019 Dec 15, In : Bioinformatics (Oxford, England). 35, 24, p. 5306-5308 3 p.

Research output: Contribution to journalArticle

Open Access
Quality Control
RNA
Quality control
Cell
Bioinformatics
4 Citations (Scopus)

Systems Biology Analyses Show Hyperactivation of Transforming Growth Factor-β and JNK Signaling Pathways in Esophageal Cancer

Blum, A. E., Venkitachalam, S., Ravillah, D., Chelluboyina, A. K., Kieber-Emmons, A. M., Ravi, L., Kresak, A., Chandar, A. K., Markowitz, S. D., Canto, M. I., Wang, J. S., Shaheen, N. J., Guo, Y., Shyr, Y., Willis, J. E., Chak, A., Varadan, V. & Guda, K., 2019 May, In : Gastroenterology. 156, 6, p. 1761-1774 14 p.

Research output: Contribution to journalArticle

Systems Biology
Transforming Growth Factors
Esophageal Neoplasms
Adenocarcinoma
Phosphotransferases
2018
8 Citations (Scopus)

Bioinformatic analysis of endogenous and exogenous small RNAs on lipoproteins

Allen, R. M., Zhao, S., Ramirez Solano, M. A., Zhu, W., Michell, D. L., Wang, Y., Shyr, Y., Sethupathy, P., Linton, M. F., Graf, G. A., Sheng, Q. & Vickers, K. C., 2018 Jan 1, In : Journal of Extracellular Vesicles. 7, 1, 1506198.

Research output: Contribution to journalArticle

Open Access
Computational Biology
Lipoproteins
Genome
RNA
MicroRNAs

Design and conduct of clinical trials for breast cancer

Klimberg, V. S., Shyr, Y. & Wells, T., 2018 Jan 1, The Breast: Comprehensive Management of Benign and Malignant Diseases. Elsevier Inc., p. 362-376.e1

Research output: Chapter in Book/Report/Conference proceedingChapter

Controlled Clinical Trials
Clinical Trials
Breast Neoplasms
National Institutes of Health (U.S.)
Laboratory Animals
5 Citations (Scopus)

Directed solutions to address differences in access to liver transplantation

Ye, F., Sheng, Q., Feurer, I. D., Zhao, Z., Fan, R., Teng, J., Ping, J., Rega, S. A., Hanto, D. W., Shyr, Y. & Karp, S. J., 2018 Nov, In : American Journal of Transplantation. 18, 11, p. 2670-2678 9 p.

Research output: Contribution to journalArticle

End Stage Liver Disease
Liver Transplantation
Transplants
Quality of Health Care
Hepatitis C
3 Citations (Scopus)

Dynamics of Zebrafish Heart Regeneration Using an HPLC-ESI-MS/MS Approach

Ma, D., Tu, C., Sheng, Q., Yang, Y., Kan, Z., Guo, Y., Shyr, Y., Scott, I. C. & Lou, X., 2018 Mar 2, In : Journal of Proteome Research. 17, 3, p. 1300-1308 9 p.

Research output: Contribution to journalArticle

Zebrafish
Regeneration
High Pressure Liquid Chromatography
Proteins
Functional analysis

Erratum to: Feasibility trial for primary stroke prevention in children with sickle cell anemia in Nigeria (SPIN trial) (American Journal of Hematology, (2017), 92, 8, (780-788), 10.1002/ajh.24770)

Galadanci, N. A., Umar Abdullahi, S., Vance, L. D., Musa Tabari, A., Ali, S., Belonwu, R., Salihu, A., Amal Galadanci, A., Wudil Jibir, B., Bello-Manga, H., Neville, K., Kirkham, F. J., Shyr, Y., Phillips, S., Covert, B. V., Kassim, A. A., Jordan, L. C., Aliyu, M. H. & DeBaun, M. R., 2018 Mar, In : American Journal of Hematology. 93, 3, p. E83

Research output: Contribution to journalComment/debate

Open Access
Medication Adherence
Sickle Cell Anemia
Hematology
Primary Prevention
Nigeria

First-line Chemotherapy Responsiveness and Patterns of Metastatic Spread Identify Clinical Syndromes Present Within Advanced KRAS Mutant Non–Small-cell Lung Cancer With Different Prognostic Significance

Iams, W. T., Yu, H., Shyr, Y., Patil, T., Horn, L., McCoach, C., Kelly, K., Doebele, R. C. & Camidge, D. R., 2018 Nov, In : Clinical Lung Cancer. 19, 6, p. 531-543 13 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Drug Therapy
Survival
Confidence Intervals
Disease-Free Survival
8 Citations (Scopus)

Forecasting Construction Cost Index based on visibility graph: A network approach

Zhang, R., Ashuri, B., Shyr, Y. & Deng, Y., 2018 Mar 1, In : Physica A: Statistical Mechanics and its Applications. 493, p. 239-252 14 p.

Research output: Contribution to journalArticle

Visibility Graph
visibility
forecasting
Forecasting
costs
6 Citations (Scopus)

Interplay between miRNAs and host genes and their role in cancer

Liu, B., Shyr, Y., Cai, J. & Liu, Q., 2018 Jan 1, In : Briefings in functional genomics. 18, 4, p. 255-266 12 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Genes
Neoplasms
Tumors
Biological Phenomena
3 Citations (Scopus)

LNK deficiency promotes acute aortic dissection and rupture

Laroumanie, F., Korneva, A., Bersi, M. R., Alexander, M. R., Xiao, L., Zhong, X., Van Beusecum, J. P., Chen, Y., Saleh, M. A., McMaster, W. G., Gavulic, K. A., Dale, B. L., Zhao, S., Guo, Y., Shyr, Y., Perrien, D. S., Cox, N. J., Curci, J. A., Humphrey, J. D. & Madhur, M. S., 2018 Oct 18, In : JCI Insight. 3, 20

Research output: Contribution to journalArticle

Open Access
Aortic Rupture
Dissection
Angiotensin II
Neutrophils
Adoptive Transfer
21 Citations (Scopus)

Longitudinal Cell-Free DNA Analysis in Patients with Small Cell Lung Cancer Reveals Dynamic Insights into Treatment Efficacy and Disease Relapse

Almodovar, K., Iams, W. T., Meador, C. B., Zhao, Z., York, S., Horn, L., Yan, Y., Hernandez, J., Chen, H., Shyr, Y., Lim, L. P., Raymond, C. K. & Lovly, C. M., 2018 Jan, In : Journal of Thoracic Oncology. 13, 1, p. 112-123 12 p.

Research output: Contribution to journalArticle

Open Access
Small Cell Lung Carcinoma
Recurrence
DNA
Genes
myc Genes
3 Citations (Scopus)

Nascent RNA sequencing analysis provides insights into enhancer-mediated gene regulation

Wang, J., Zhao, Y., Zhou, X., Hiebert, S. W., Liu, Q. & Shyr, Y., 2018 Aug 23, In : BMC genomics. 19, 1, 633.

Research output: Contribution to journalArticle

Open Access
RNA Sequence Analysis
Genes
Technology
DNA-Directed RNA Polymerases
Knockout Mice

Proteome analysis implicates adaptive changes in metabolism and body wall musculature of Caenorhabditis elegans Dauer Larva

Zaidi, A. K., Vukoti, K., Sheng, Q., Shyr, Y. & Miyagi, M., 2018 Jun, In : Journal of Integrated OMICS. 8, 1, p. 46-53 8 p., 237.

Research output: Contribution to journalArticle

Caenorhabditis elegans
Proteome
Metabolism
Larva
Proteins
5 Citations (Scopus)

Quantitative assessment of cell population diversity in single-cell landscapes

Liu, Q., Herring, C. A., Sheng, Q., Ping, J., Simmons, A. J., Chen, B., Banerjee, A., Li, W., Gu, G., Coffey, R. J., Shyr, Y. & Lau, K. S., 2018 Oct 1, In : PLoS biology. 16, 10, p. e2006687

Research output: Contribution to journalArticle

Open Access
Cells
Population
cells
RNA
Tissue
3 Citations (Scopus)

RnaSeqSampleSize: Real data based sample size estimation for RNA sequencing

Zhao, S., Li, C. I., Guo, Y., Sheng, Q. & Shyr, Y., 2018 May 30, In : BMC Bioinformatics. 19, 1, 191.

Research output: Contribution to journalArticle

RNA Sequence Analysis
RNA
Sample Size
Sequencing
Genes
2 Citations (Scopus)

Strategies for processing and quality control of Illumina genotyping arrays

Zhao, S., Jing, W., Samuels, D. C., Sheng, Q., Shyr, Y. & Guo, Y., 2018 Sep 28, In : Briefings in bioinformatics. 19, 5, p. 765-775 11 p.

Research output: Contribution to journalArticle

Quality Control
Quality control
Processing
Genome-Wide Association Study
Nucleotides
54 Citations (Scopus)

The impact of smoking and tp53 mutations in lung adenocarcinoma patients with targetable mutations—the lung cancer mutation consortium (LCMC2)

Aisner, D. L., Sholl, L. M., Berry, L. D., Rossi, M. R., Chen, H., Fujimoto, J., Moreira, A. L., Ramalingam, S. S., Villaruz, L. C., Otterson, G. A., Haura, E., Politi, K., Glisson, B., Cetnar, J., Garon, E. B., Schiller, J., Waqar, S. N., Sequist, L. V., Brahmer, J., Shyr, Y. & 7 others, Kugler, K., Wistuba, I. I., Johnson, B. E., Minna, J. D., Kris, M. G., Bunn, P. A. & Kwiatkowski, D. J., 2018 Mar 1, In : Clinical Cancer Research. 24, 5, p. 1038-1047 10 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Smoking
Mutation
High-Throughput Nucleotide Sequencing
Survival
3 Citations (Scopus)

Treatment options in idiopathic subglottic stenosis: Protocol for a prospective international multicentre pragmatic trial

Gelbard, A., Shyr, Y., Berry, L., Hillel, A. T., Ekbom, D. C., Edell, E. S., Kasperbauer, J. L., Lott, D. G., Donovan, D. T., Garrett, C. G., Sandhu, G., Daniero, J. J., Netterville, J. L., Schindler, J. S., Smith, M. E., Bryson, P. C., Lorenz, R. R. & Francis, D. O., 2018 Apr 1, In : BMJ open. 8, 4, e022243.

Research output: Contribution to journalArticle

Pragmatic Clinical Trials
Multicenter Studies
Pathologic Constriction
Deglutition
Therapeutics
2017
5 Citations (Scopus)

A comparative analysis between sequential boost and integrated boost intensity-modulated radiation therapy with concurrent chemotherapy for locally-advanced head and neck cancer

Vlacich, G., Stavas, M. J., Pendyala, P., Chen, S. C., Shyr, Y. & Cmelak, A. J., 2017 Jan 13, In : Radiation Oncology. 12, 1, 13.

Research output: Contribution to journalArticle

Open Access
Head and Neck Neoplasms
Radiotherapy
Drug Therapy
Gastrostomy
Survival
2 Citations (Scopus)

A peptide-retrieval strategy enables significant improvement of quantitative performance without compromising confidence of identification

Tu, C., Shen, S., Sheng, Q., Shyr, Y. & Qu, J., 2017 Jan 30, In : Journal of Proteomics. 152, p. 276-282 7 p.

Research output: Contribution to journalArticle

Peptides
Proteins
Proteomics
Proteome
Labeling
28 Citations (Scopus)

A randomized phase II neoadjuvant study of cisplatin, paclitaxel with or without everolimus in patients with stage II/III triple-negative breast cancer (TNBC): Responses and long-term outcome correlated with increased frequency of DNA damage response gene mutations, TNBC subtype, AR status, and Ki67

Jovanovic, B., Mayer, I. A., Mayer, E. L., Abramson, V. G., Bardia, A., Sanders, M. E., Kuba, M. G., Estrada, M. V., Beeler, J. S., Shaver, T. M., Johnson, K. C., Sanchez, V., Rosenbluth, J. M., Dillon, P. M., Forero-Torres, A., Chang, J. C., Meszoely, I. M., Grau, A. M., Lehmann, B. D., Shyr, Y. & 4 others, Sheng, Q., Chen, S. C., Arteaga, C. L. & Pietenpol, J. A., 2017 Aug 1, In : Clinical Cancer Research. 23, 15, p. 4035-4045 11 p.

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
DNA Damage
Mutation
Arm
Genes

Bivariate Poisson models with varying offsets: An application to the paired mitochondrial DNA dataset

Su, P. F., Mau, Y. L., Guo, Y., Li, C. I., Liu, Q., Boice, J. D. & Shyr, Y., 2017 Mar 1, In : Statistical Applications in Genetics and Molecular Biology. 16, 1, p. 47-58 12 p.

Research output: Contribution to journalArticle

Poisson Model
Mitochondrial DNA
Poisson Regression
Mutation
DNA

Corrigendum to "Comparative Study of Exome Copy Number Variation Estimation Tools Using Array Comparative Genomic Hybridization as Control"

Guo, Y., Sheng, Q., Samuels, D. C., Lehmann, B., Bauer, J. A., Pietenpol, J. & Shyr, Y., 2017 Jan 1, In : BioMed research international. 2017, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Exome
Comparative Genomic Hybridization
corrigendum
3 Citations (Scopus)

Determining penetration of prostate-specific antigen screening recommendations

Thomas, C. R. & Shyr, Y., 2017 Jan 1, In : JAMA Oncology. 3, 5, 1 p.

Research output: Contribution to journalEditorial

Open Access
4 Citations (Scopus)

Estimating relative mitochondrial DNA copy number using high throughput sequencing data

Zhang, P., Lehmann, B. D., Samuels, D. C., Zhao, S., Zhao, Y. Y., Shyr, Y. & Guo, Y., 2017 Oct, In : Genomics. 109, 5-6, p. 457-462 6 p.

Research output: Contribution to journalArticle

Open Access
Mitochondrial DNA
Mitochondria
Polymerase Chain Reaction
Genome
Exome
33 Citations (Scopus)

Etoposide and cisplatin versus paclitaxel and carboplatin with concurrent thoracic radiotherapy in unresectable stage III non-small cell lung cancer: A multicenter randomized phase III trial

Liang, J., Bi, N., Wu, S., Chen, M., Lv, C., Zhao, L., Shi, A., Jiang, W., Xu, Y., Zhou, Z., Wang, W., Chen, D., Hui, Z., Lv, J., Zhang, H., Feng, Q., Xiao, Z., Wang, X., Liu, L., Zhang, T. & 7 others, Du, L., Chen, W., Shyr, Y., Yin, W., Li, J., He, J. & Wang, L., 2017 Apr 1, In : Annals of Oncology. 28, 4, p. 777-783 7 p., mdx009.

Research output: Contribution to journalArticle

Open Access
Carboplatin
Etoposide
Non-Small Cell Lung Carcinoma
Paclitaxel
Cisplatin
14 Citations (Scopus)

Feasibility trial for primary stroke prevention in children with sickle cell anemia in Nigeria (SPIN trial)

Galadanci, N. A., Umar Abdullahi, S., Vance, L. D., Musa Tabari, A., Ali, S., Belonwu, R., Salihu, A., Amal Galadanci, A., Wudil Jibir, B., Bello-Manga, H., Neville, K., Kirkham, F. J., Shyr, Y., Phillips, S., Covert, B. V., Kassim, A. A., Jordan, L. C., Aliyu, M. H. & DeBaun, M. R., 2017 Aug, In : American Journal of Hematology. 92, 8, p. 780-788 9 p.

Research output: Contribution to journalArticle

Open Access
Sickle Cell Anemia
Primary Prevention
Nigeria
Hydroxyurea
Stroke
2 Citations (Scopus)

Functional data classification using covariate-adjusted subspace projection

Li, P. L., Chiou, J. M. & Shyr, Y., 2017 Nov 1, In : Computational Statistics and Data Analysis. 115, p. 21-34 14 p.

Research output: Contribution to journalArticle

Functional Data
Data Classification
Covariates
Subspace
Projection
22 Citations (Scopus)

Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance

Giltnane, J. M., Hutchinson, K. E., Stricker, T. P., Formisano, L., Young, C. D., Estrada, M. V., Nixon, M. J., Du, L., Sanchez, V., Ericsson, P. G., Kuba, M. G., Sanders, M. E., Mu, X. J., Van Allen, E. M., Wagle, N., Mayer, I. A., Abramson, V., Gómez, H., Rizzo, M., Toy, W. & 15 others, Chandarlapaty, S., Mayer, E. L., Christiansen, J., Murphy, D., Fitzgerald, K., Wang, K., Ross, J. S., Miller, V. A., Stephens, P. J., Yelensky, R., Garraway, L., Shyr, Y., Meszoely, I., Balko, J. M. & Arteaga, C. L., 2017 Aug 9, In : Science Translational Medicine. 9, 402, aai7993.

Research output: Contribution to journalArticle

Open Access
letrozole
Estrogens
Breast Neoplasms
Estrogen Receptor Modulators
Neoplasms
9 Citations (Scopus)

Identification of active miRNA promoters from nuclear run-on RNA sequencing

Liu, Q., Wang, J., Zhao, Y., Li, C. I., Stengel, K. R., Acharya, P., Johnston, G., Hiebert, S. W. & Shyr, Y., 2017 Jul 1, In : Nucleic acids research. 45, 13, e121.

Research output: Contribution to journalArticle

RNA Sequence Analysis
MicroRNAs
Transcription Initiation Site
Transcription Factors
Statistical Models
10 Citations (Scopus)

IGFBP3 modulates lung tumorigenesis and cell growth through IGF1 signaling

Wang, Y. A., Sun, Y., Palmer, J., Solomides, C., Huang, L. C., Shyr, Y., Dicker, A. P. & Lu, B., 2017 Jul, In : Molecular Cancer Research. 15, 7, p. 896-904 9 p.

Research output: Contribution to journalArticle

Open Access
Insulin-Like Growth Factor Binding Protein 3
Carcinogenesis
Lung
Growth
Lung Neoplasms

Implementing a standard-of-care clinic for stroke prevention in children with sickle cell disease in Nigeria: A feasible strategy outside a clinical trial setting

Galadanci, N. A., Abdullahi, S. U., Vance, L. D., Tabari, M. A., Abubakar, S., Belonwu, R., Salihu, A., Galadanci, A. A., Jibir, B. W., Gambo, S., Suwaid, S., Bello-Manga, H., Neville, K., Kirkham, F., Shyr, Y., Phillips, S., Covert, B. V., Kassim, A. A., Trevathan, E., Jordan, L. C. & 2 others, Aliyu, M. H. & DeBaun, M. R., 2017 Dec 8, In : Blood Advances. 1, p. 23-25 3 p.

Research output: Contribution to journalShort survey

Open Access
23 Citations (Scopus)

Improvements and impacts of GRCh38 human reference on high throughput sequencing data analysis

Guo, Y., Dai, Y., Yu, H., Zhao, S., Samuels, D. C. & Shyr, Y., 2017 Mar 1, In : Genomics. 109, 2, p. 83-90 8 p.

Research output: Contribution to journalArticle

Open Access
Human Genome
Genome
Single Nucleotide Polymorphism
16 Citations (Scopus)

Institute of Medicine Measures of Social and Behavioral Determinants of Health: A Feasibility Study

Giuse, N. B., Koonce, T. Y., Kusnoor, S. V., Prather, A. A., Gottlieb, L. M., Huang, L. C., Phillips, S. E., Shyr, Y., Adler, N. E. & Stead, W. W., 2017 Feb 1, In : American Journal of Preventive Medicine. 52, 2, p. 199-206 8 p.

Research output: Contribution to journalArticle

Social Determinants of Health
National Academies of Science, Engineering, and Medicine (U.S.) Health and Medicine Division
Feasibility Studies
Random Allocation
Health
7 Citations (Scopus)

Integrated expression analysis identifies transcription networks in mouse and human gastric neoplasia

Chen, Z., Soutto, M., Rahman, B., Fazili, M. W., Peng, D. F., Blanca Piazuelo, M., Chen, H., Kay Washington, M., Shyr, Y. & El-Rifai, W., 2017 Jul, In : Genes Chromosomes and Cancer. 56, 7, p. 535-547 13 p.

Research output: Contribution to journalArticle

Stomach
Stomach Neoplasms
Neoplasms
Catenins
Knockout Mice
7 Citations (Scopus)

Integrated molecular analysis reveals complex interactions between genomic and epigenomic alterations in esophageal adenocarcinomas

Peng, D., Guo, Y., Chen, H., Zhao, S., Washington, K., Hu, T., Shyr, Y. & El-Rifai, W., 2017 Jan 19, In : Scientific reports. 7, 40729.

Research output: Contribution to journalArticle

Open Access
Epigenomics
Adenocarcinoma
Gene Expression
Methylation
Genes