A 100-Channel 1-mW implantable neural recording IC

Xiaodan Zou, Lei Liu, Jia Hao Cheong, Lei Yao, Peng Li, Ming Yuan Cheng, Wang Ling Goh, Ramamoorthy Rajkumar, Gavin Stewart Dawe, Kuang-Wei Cheng, Minkyu Je

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73 Citations (Scopus)

Abstract

This paper presents a fully implantable 100-channel neural interface IC for neural activity monitoring. It contains 100-channel analog recording front-ends, 10 multiplexing successive approximation register ADCs, digital control modules and power management circuits. A dual sample-and-hold architecture is proposed, which extends the sampling time of the ADC and reduces the average power per channel by more than 50% compared to the conventional multiplexing neural recording system. A neural amplifier (NA) with current-reuse technique and weak inversion operation is demonstrated, consuming 800 nA under 1-V supply while achieving an input-referred noise of 4.0 μV \rm rms in a 8-kHz bandwidth and a NEF of 1.9 for the whole analog recording chain. The measured frequency response of the analog front-end has a high-pass cutoff frequency from sub-1 Hz to 248 Hz and a low-pass cutoff frequency from 432 Hz to 5.1 kHz, which can be configured to record neural spikes and local field potentials simultaneously or separately. The whole system was fabricated in a 0.18-μhbox m standard CMOS process and operates under 1 V for analog blocks and ADC, and 1.8 V for digital modules. The number of active recording channels is programmable and the digital output data rate changes accordingly, leading to high system power efficiency. The overall 100-channel interface IC consumes 1.16-mW total power, making it the optimum solution for multi-channel neural recording systems.

Original languageEnglish
Article number6479332
Pages (from-to)2584-2596
Number of pages13
JournalIEEE Transactions on Circuits and Systems I: Regular Papers
Volume60
Issue number10
DOIs
Publication statusPublished - 2013 Mar 19

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

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  • Cite this

    Zou, X., Liu, L., Cheong, J. H., Yao, L., Li, P., Cheng, M. Y., Goh, W. L., Rajkumar, R., Dawe, G. S., Cheng, K-W., & Je, M. (2013). A 100-Channel 1-mW implantable neural recording IC. IEEE Transactions on Circuits and Systems I: Regular Papers, 60(10), 2584-2596. [6479332]. https://doi.org/10.1109/TCSI.2013.2249175