A case of minimal-change nephrotic syndrome in pediatric lupus erythematosus: Just a coincidence?

Y. T. Wang, H. H. Chou, F. F. Chen, M. J. Chen, Yuan Yow Chiou

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

A 14-year old girl with lupus erythematosus (LE) who initially showed as discoid lupus and followed with nephrotic syndrome one year later. Concomitant piroxicam and indomethacin were prescribed for her arthritis, which preceded two months before the onset of nephrotic syndrome. Histology from renal biopsy showed minimal-change nephrotic syndrome (MCNS). After continuous treatment for six months, nephrotic syndrome resolved completely and no signs of relapse were noted over 14 years of follow-up. For the children, it is rare to have both LE and MCNS simultaneously; sequela of nonsteroidal anti-inflammatory drugs also seldom results in nephrotic syndrome. Though their relationship is still not defined, the possibility of LE combined with MCNS must be differentiated in patients with lupus and severe proteinuria.

Original languageEnglish
Pages (from-to)244-247
Number of pages4
JournalLupus
Volume15
Issue number4
DOIs
Publication statusPublished - 2006 May 10

All Science Journal Classification (ASJC) codes

  • Rheumatology

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