A cellular ELISA to screen lectin-like compounds for cancer cell binding

C. P. Chang, W. C. Cheng, H. Y. Lei

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Lectins are carbohydrate-binding proteins that can modulate cellular activity through cell membrane glycoproteins. A cell-based binding was set up to screen the lectin-like substances in natural products. Lectins, after binding to tumor cells, are detected with a biotinylated carbohydrate-polyacrylamide complex by ELISA. Sugar specificity can also be determined within the assay.

Original languageEnglish
Pages (from-to)182-188
Number of pages7
JournalLetters in Drug Design and Discovery
Volume2
Issue number3
DOIs
Publication statusPublished - 2005 May

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery

Fingerprint

Dive into the research topics of 'A cellular ELISA to screen lectin-like compounds for cancer cell binding'. Together they form a unique fingerprint.

Cite this